Mdem005844.1
Basic Information
- Insect
- Microplitis demolitor
- Gene Symbol
- -
- Assembly
- GCA_000572035.2
- Location
- NW:72483-80483[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 1.6e-13 4.4e-10 38.4 0.2 5 72 310 374 307 377 0.86 2 2 2.4 6.9e+03 -3.9 0.1 16 26 629 639 629 640 0.90
Sequence Information
- Coding Sequence
- ATGGATGTCGTGGCTACCGATGTAAATGGCGGGAACGCTGAAGTGGCGCGCGACGACGATGTGCCAGATCCAGGAGTTGTTCAACTCACTAGTAAATCGCCAAAAGTTGATGAGGATAAAGACACCAAGGATAAGGAAATTAACGACGTAAAAGAGGACAAAGATAAGGATGTTGAGATGGAAGATGATAAAAAGGATGTGAAAGTAGAAGAGGTTCAGAAAAAAGAAGAACAAGAGACGATTGTAGTTAATGAGACTGAAAAAATTGACGAGCAAGAGGTTAATGGTGATGTCAAGGGTGTCAATGTTtctgttgttaaaaaaaatatgacaccTGTGACTAAACGAAAATTACGTAAAACTAAAGCCAATTCTACTAGTGCTGTCGAGAGTGAACACCAGGATTCACCCTCAGTAAATGCAAATACTAATGTGAATGCTAATTCTAATAATACCAGAACACGGAAtcaaaagagaaaattatcAGAACCTGATAATCATACATCCGATGATTCGATGGATTTTATTGGTTTTGATAGCAGTAGTTTGTTAAAAGTTAATCCTGCTACggaaattttgttgaaattgATCGCCGAAGCTGAGGCAGAGATTTCATCACCGCAACCATCTGCTAAACGTCCTAAGCGTTCGCTGTCCAAGGGTCCAGTTCGTAGaaatgttgaattaaaaacagaCGATCATCAGAcagAAGTAGCAAAAGGTAAAAAGAAATTGGATAAATCGGACGGTGAAGTCGATAGTGGAAATGCTGGTGCTGTAACTGCTGTTGTTAAAAATGACGCTGGAAAATCACCACCGTCTGCTAAAACTCCAGTTGTGAGTAGGCGGGGAATGAGAAACTCCCATGCACCACAAACTTCTAGTATTGCTGCAGCGAAACAAAAAGTTTCGGCTGATGTGACTAATCCAGAATACAAAGAACCTTTCAAGTATGGATGGAAACGCGAGCTTGTGTATAAAACTGAGACTGATTCAACGAAAAAAGTTGTTGAAGTTTCTTATTACACGCCAAAGGGTAAAAAAGTTCGGAGTCTTAGAGAAATTGCCGAATTCctgaatacTAAAGAATTGAcggtagataattttatatttaccaaAGAACCAACGGGTATTAATGATCCGCAATATGAAATAATCAAAGACGAAACAACTCCCATCAGTACTCCAGTCAGCGCGGGGCCTGCCAAAAAAATAGGAACTGGCAAGAAAGCTGCCGTTACAAAAAGACTTACCGGAAAAATATCTCCAACACCAGCTAAAACTCttgcaaaaaatttacctttgAAAACAAGTACTCCCGGGATTAAAGTCAAAGTTCCCGTCAAAAGAGGTTCACTAAGAAAAGACGTATCACCGCCCAAAGAAACTGATGTGCTCGGGTGGACCAACTCGTCAAACACCACGAGACGCAGTCAAGCTGCCACGGAAAAAACGACGCCTTACAAATCAAAGAGGTCATTGAaGACCAAACTCCAGGAACCCTGCAGTATCCGGTGTTCTATGAGCATGGGTCTGATACCAAGTCTTCAATGCTGTGTCTGCCTCTGTCTGTATCATCCTGAATGCGTAGGCCACGCTGAGAATTCTACCAGTGAAGATTATGTTTGCaagaattgtCGGCACGACAATGAGGAAggtaaaaaagtttctataacACCACCGCCATTGATACCAATAAGTATGATCGGTACACAAAATGTTAAATCACTTTTCCCGCCAATTGATCGACAATCACCCCCGAGagttttatctaaaaattcaaaacctGACAGTGAatattattcgaaaaattcatcaaaatcaCATCGAGATTCATTGCCATCAACTGgtgacaataaattaaataccgcCGCTTGGTATTCGAGGAGAGATTTTATGCAGAGACAAGACGGCTCGGAGCCTAAACCAGCACAAAATATCGCGCTGTTAGCTGGCAAAAGATATATTGTTGTACCGAAAAATAACGCTGGTTCAGTTCAACCAGCAATCAGGCCCAATAAAacccaaaataaattatcaatcgatgacgttgataaaataaattatcctaGAGAAATAGGATCTAAAGAGTCTAAAGCGCCGAAAGAAGTATCAACTGGACTTCCAAGTGAAGAAAttgttaaagataaaaataatgaaaagagTCAAGAGTCAAAGACAGCAACGATCGACGTTGAGGAACCGCAGAGACAAAGTTCCGAGTTGAGTGACAAGATAGATGACACTAGCATTAGTGAAACTCCTGTAGGCactttagaaaaaattcacaaaacaCTTGAAGATCAAGTGGAGGATGATGCGCTGGTACAAGAAGTTAAAGATAACGACCAAGTGCAAGAACAGGAAAATTCACACGATGGTATTGAGGAAAATGTACCAGCTACTGTTGGAAGGAAAATAGATTCAGGTAAAGAGATTGCTGATGACAAATCAATTGAAGAAAAAGACATTGAAAGATCAGAGTCCATGGATACTGATGGTTCAAACGCATCTGATGAAATGCCGATCAAAGAATCTGAATTTGATGCTGTAGCTGCAGCTGCTGTATCGAAAGATATTTTAGAATCAGAAGCATCTGAGCTAACAGTGAGTCCAGTGAAACAAACGGCGGGTAATTtgaatgaggaaaaaaatcaacaagttggaaccaatgataaaaaagagGTGGAGGCAGACAAaaAGAAAGCTGTGGCACCGCTGGTTGAAGTCGATCAGAGACAGTACTTTATGTCGACAGTATGCTCTGGTTACAATGCACTGTCACGAGTTTTCCAGTATCTTAAAGTACAAGAATTATTGCGCGCAGCGCGTGTATGTAAAATGTGGCGCGATTTAGCTGCACATCCTGCGCTGTGGAAGACAGTCCGTATGAAGAATAGTCAGGTCACCGATTGGGACGGATTGGTAGCAACCCTACAGAGGCACGGTACTGAACATCTTGATTTACGTAAAATGCTGATTGCCCCTGAATCTGACAGTATTTGGCAAAAATTTGTATCAGTTATTCCCAATGTCAAGACTCTTATCAAACTCGAACTGTGCCGCTGTCCCGTGATGGTTGTAGAGGAAGTAATTAAAGTTTGTCCGCAATTGCAAGTACTCAGTGCCATGTCAATAAAATGTGATTGGCTCAATTTAGAGGATAttggtaatttaaaatcttgtGAAGAATTAAGACTCAAAGCCATCACTGGTATGTCATTACACGGTGATTTAACGCCACTACAAAATCTCACTCAGCTGTCGCACTTGAGTCTAACGTCAGTTAAAGaacttggtaaaaaaaaaatagacataCTGGCGTCGCTTGTTAATCTCGAGTCACTTGAGTTGGGCGAGTGCTCGGATTTTTCATCAAAGTTTGGCACTGCGGTGTTGTGTAAACTCACAAAACTCGAACGATTGAGACTTGAAAAGGGTCAAGGTACTTGTTGTACCTTTGATATACTTAAAGGTGTTGCTAAACTCGATAAATTACATCAATTGGAACTGGTCAACTTTGACGTTAAAAATGGCTTTGATAAACACCTGgcaaattgtaaaaatattaagaggCTGCTTATTATACCGACGTATATCTCACAGTCAGCTACGTCAAATAATATGGTATTGGGTGGTGTTACTGAGTTATCTGACAGTCTCACGTATTTCGTCTGGGGTGTAACACTAGAATTGTTAAGAGTTACTCAATTATTTGTCGACCAATGTAATCAAATGAATAAACAAGTGTCTGGTGATTCGATACCCGTATTGAAACCAGTACCTTGTTTGAAACTTATTGAGGATGCTGATGACACGAAGATGGCGTCCAaagCTGAAGAAAAATCAACAAATTCATCAAATCCTCAAGTAGATATTTTACCTTTACCACAACTGCAAAAACTTCTTTTGACAGCATTACCGAAAACAcgagtgaaaatattaatgataccTTTCCAAGCTACCTGGAGACAAAGTATTTCAGACACTGCATCACAGTAa
- Protein Sequence
- MDVVATDVNGGNAEVARDDDVPDPGVVQLTSKSPKVDEDKDTKDKEINDVKEDKDKDVEMEDDKKDVKVEEVQKKEEQETIVVNETEKIDEQEVNGDVKGVNVSVVKKNMTPVTKRKLRKTKANSTSAVESEHQDSPSVNANTNVNANSNNTRTRNQKRKLSEPDNHTSDDSMDFIGFDSSSLLKVNPATEILLKLIAEAEAEISSPQPSAKRPKRSLSKGPVRRNVELKTDDHQTEVAKGKKKLDKSDGEVDSGNAGAVTAVVKNDAGKSPPSAKTPVVSRRGMRNSHAPQTSSIAAAKQKVSADVTNPEYKEPFKYGWKRELVYKTETDSTKKVVEVSYYTPKGKKVRSLREIAEFLNTKELTVDNFIFTKEPTGINDPQYEIIKDETTPISTPVSAGPAKKIGTGKKAAVTKRLTGKISPTPAKTLAKNLPLKTSTPGIKVKVPVKRGSLRKDVSPPKETDVLGWTNSSNTTRRSQAATEKTTPYKSKRSLKTKLQEPCSIRCSMSMGLIPSLQCCVCLCLYHPECVGHAENSTSEDYVCKNCRHDNEEGKKVSITPPPLIPISMIGTQNVKSLFPPIDRQSPPRVLSKNSKPDSEYYSKNSSKSHRDSLPSTGDNKLNTAAWYSRRDFMQRQDGSEPKPAQNIALLAGKRYIVVPKNNAGSVQPAIRPNKTQNKLSIDDVDKINYPREIGSKESKAPKEVSTGLPSEEIVKDKNNEKSQESKTATIDVEEPQRQSSELSDKIDDTSISETPVGTLEKIHKTLEDQVEDDALVQEVKDNDQVQEQENSHDGIEENVPATVGRKIDSGKEIADDKSIEEKDIERSESMDTDGSNASDEMPIKESEFDAVAAAAVSKDILESEASELTVSPVKQTAGNLNEEKNQQVGTNDKKEVEADKKKAVAPLVEVDQRQYFMSTVCSGYNALSRVFQYLKVQELLRAARVCKMWRDLAAHPALWKTVRMKNSQVTDWDGLVATLQRHGTEHLDLRKMLIAPESDSIWQKFVSVIPNVKTLIKLELCRCPVMVVEEVIKVCPQLQVLSAMSIKCDWLNLEDIGNLKSCEELRLKAITGMSLHGDLTPLQNLTQLSHLSLTSVKELGKKKIDILASLVNLESLELGECSDFSSKFGTAVLCKLTKLERLRLEKGQGTCCTFDILKGVAKLDKLHQLELVNFDVKNGFDKHLANCKNIKRLLIIPTYISQSATSNNMVLGGVTELSDSLTYFVWGVTLELLRVTQLFVDQCNQMNKQVSGDSIPVLKPVPCLKLIEDADDTKMASKAEEKSTNSSNPQVDILPLPQLQKLLLTALPKTRVKILMIPFQATWRQSISDTASQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01004250;
- 90% Identity
- iTF_01006067; iTF_01005087; iTF_01004250;
- 80% Identity
- -