Basic Information

Gene Symbol
Prdm15
Assembly
GCA_000572035.2
Location
NW:2810454-2814172[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 1.6 1.1e+02 2.9 0.1 2 23 242 263 241 263 0.94
2 14 0.00025 0.018 14.9 1.9 3 23 272 293 271 293 0.91
3 14 1.1e-05 0.00077 19.2 1.8 1 23 420 442 420 442 0.97
4 14 0.00043 0.031 14.1 1.9 1 23 446 469 446 469 0.96
5 14 7.1e-06 0.00051 19.7 0.7 1 23 479 501 479 501 0.97
6 14 0.14 10 6.2 5.3 2 20 506 524 506 526 0.93
7 14 0.00067 0.048 13.5 0.5 2 23 531 552 531 552 0.97
8 14 2.6e-05 0.0019 17.9 2.2 3 23 573 593 572 593 0.98
9 14 0.0012 0.084 12.7 1.1 1 23 598 620 598 620 0.98
10 14 0.00036 0.026 14.4 0.1 2 23 626 647 625 647 0.95
11 14 0.0012 0.085 12.7 8.6 1 23 652 675 652 675 0.96
12 14 0.0023 0.16 11.8 5.4 1 23 681 703 681 703 0.97
13 14 0.0027 0.19 11.6 6.6 1 23 710 733 710 733 0.95
14 14 0.15 11 6.1 6.4 1 23 738 761 738 761 0.95

Sequence Information

Coding Sequence
atgttgtcaataaaacaaaaatccgaagacgataataaattaattggttGCGATGTTGGCAACAACAacataacaattaatttttcaggATGCAATATTTGCGGGGATTCCCACAGCACTCATgagtgttattttttattaaatttaaactacatcaaAGACACTGAGACAATATCACGAGCACGTCAGACATTACCCAAAGACCTGGAGATCACTCGAATGGCTGATGGAACGACTAGTATAATTGCCAAGTGTGATTACCAACGAGGAACAACCTTTGGACCTTTCGAATCCAAACGTAACTGGGCAATGAACCCTGCGACTAATTTTCCTATCAAGGTTTTCGGAGAGTCGGTCAATGATACTTATTACCTAGAGTATTCCGACGAGGACATCAGTAACTGGATGTGCTTCGTACTGCCTGCCACTAACGCCCGGGAacagaatttaatttgctatcAAATGAAGCAGGATATTTTTTACACGGCGATGAGAACGATTACAGCTGGAGAAGAGTTGAGAGTCTGGTACGCGCCGTACTATGCGCAGAAGATGAAGATGCCGTTGTATATAACCGATTCTACGAGTCAAGACAAACCCATTCAGATGGTCGTGGCTAAAGATCAGGACCCGCTGGAGGTGCTAGACAAAGCTATGGCGCAGGAATTAGCCAAGAGACTTCCAGCTACGCAGCTGGGTGCTAAAGATGATAAGAAGATTTGGACATGTCGTATTTGCTCGGTGACGATTAATTCAGTGGTCGCTTACGCAAAGCATCAGATGGATCACTACAAGCCTCTAGTTGGGTCTTTTTGTACtgtttgtgataaaaaattttctagtgtCTCTGCCTTAGAGAAACATAGAGCTGACTGTCATGATTCGGCGGTCAGTGAAGATATTGGGATACCGACTTCGGCGAACCAGCAGCAGCAAAACGCCGcgactattttaaatatgagcGAGGATTTCATGACGGGAAAAGAAAATCAGCATGATCTATCACTGCTggataattcaattaatactaATGATTTGCTTCATCATGAGGGAAATCTTATAGAAAATTCTTCATTGAAATCAATCCTTGAGAATCAGTGTTTGAATATGAACATAAGTTCAATAGCTGAATCtattttatctgaaaatatATCAGGTGCTGattcagttaaatttaatgttgaaGAATTGTCATCTGAACTGCTAGACATATCTCCAGATGTTGATCAGAGAACTACTGGACGTTCGATTGATGATTTTGATTGTGATATTTGCGGTAAAAAATTCCAGcgtgttaattatttgtatcgtCATTTACGTAAACATACTGGGGAATTCATTTGTCCCACTTGTTTGTGCGTTTTTGCTAGAAAAGACAATTTGCTGTCGCATGTTTGCTCAGCTCATACGacacagaataaaaataacgtaCGCTATCAGTGCTCATATTGTCCTAAAAATTTTGCGGTtgaaaaatatctgaaaagACACATAGCGCAGCACGTGGAATTCAATCGCTGCAAGAGATGCCGTCATAAATTTACGACAAAGTCTGAACTGGACTCACACAAATGTGCGGCACCCAAGCCAGTTTGCGGACagtgtggaaaaaaatttctcaacgTAGTGTATCTTAATCGTCATATAAAAAGACACAATGAGGTGCCAAAAGTCCCcaagaaaagaataaaaaatgtggAAGAAAAGCCGGCGATTTGTGAAAAATGcggggaaatttttaaaaatctctgCAGTCTTCAGCAGCATCAAAGATCTCATGGCGAAAGAACTTATGAGTGTGATATTTGTAACCGACGTTTTCATCGGATCGGTGTTTTGAAGGAACATAAAGCCACTCATCAGAATGTCGAGCTACCTTGCAATATttgcgataaaaaattaaaaagtaaaaaagctCTGGACGTTCACATTCTGCTGCATGGAAACAAAAAGTTTCAGTGCGACAAGTGCGACAAGAGtttctttcaaaaatgtaattatctcAAGCACTACAAACACGTTCATGCAGAAAAGAGCACTCACACTTGCTCACACTGTTCAATGCAATTCaccaataaaataacttataataaACATATCGCGAGTCACAGTAAAACAACTGCTGAATTTCTCTGCAATActtgcaataaatattttcacactCAGGCTAAACTTAACAGACATGTTCAGACTTGTCACAGTGGTATTATTTATCGTTGTCCTTTCTGCAAGATGACTGCAAGACATCGTCACAGTATGAGAAGACACTTTGAGAGACAGCATAAAGATTCAAATGATGAATGGAATAAACCAGGATTTGTTAATCAGTTTGCTGAAAAATCACcggttgaatttattaaaaataattcgaaaaaaccTGGTACTTCTAATAAACGAGTTTTACATTCTAAACAACCATCAGTTGGATCAAATGCTGAACCAGTTATTGGACCAATTGCTGGATCAATTACTGGACCAATTGCTGGATCAATTACTGAACCAATTGTTGGAACAAGTACTGGACCAATTACAGGATCAGTTAATGAATCAATTACAGGTTCAGTTAATGGGCCAATAACAGGATCAGTTACTGGACCAATAACTGGATCAGTTACTGGAGCAATTACAGGTTCAGTAGTTGAATCATTtcctgttaatttaaataccgtACAAGTAAATCaagttgaagaaaataatcaagttttgatggaaaatataaaagttgatCAACAAATAAACAATACTCAGCTACTAAATGATGTACCACAACTTAGTATTGATACAGATTCACAACTTGCTGAATCTGTTTTAAataacacatatatttttggtgAAGATGGCGATATCATGTTCTACGTCTTGGATAATAATCCCATCCCGggttactaa
Protein Sequence
MLSIKQKSEDDNKLIGCDVGNNNITINFSGCNICGDSHSTHECYFLLNLNYIKDTETISRARQTLPKDLEITRMADGTTSIIAKCDYQRGTTFGPFESKRNWAMNPATNFPIKVFGESVNDTYYLEYSDEDISNWMCFVLPATNAREQNLICYQMKQDIFYTAMRTITAGEELRVWYAPYYAQKMKMPLYITDSTSQDKPIQMVVAKDQDPLEVLDKAMAQELAKRLPATQLGAKDDKKIWTCRICSVTINSVVAYAKHQMDHYKPLVGSFCTVCDKKFSSVSALEKHRADCHDSAVSEDIGIPTSANQQQQNAATILNMSEDFMTGKENQHDLSLLDNSINTNDLLHHEGNLIENSSLKSILENQCLNMNISSIAESILSENISGADSVKFNVEELSSELLDISPDVDQRTTGRSIDDFDCDICGKKFQRVNYLYRHLRKHTGEFICPTCLCVFARKDNLLSHVCSAHTTQNKNNVRYQCSYCPKNFAVEKYLKRHIAQHVEFNRCKRCRHKFTTKSELDSHKCAAPKPVCGQCGKKFLNVVYLNRHIKRHNEVPKVPKKRIKNVEEKPAICEKCGEIFKNLCSLQQHQRSHGERTYECDICNRRFHRIGVLKEHKATHQNVELPCNICDKKLKSKKALDVHILLHGNKKFQCDKCDKSFFQKCNYLKHYKHVHAEKSTHTCSHCSMQFTNKITYNKHIASHSKTTAEFLCNTCNKYFHTQAKLNRHVQTCHSGIIYRCPFCKMTARHRHSMRRHFERQHKDSNDEWNKPGFVNQFAEKSPVEFIKNNSKKPGTSNKRVLHSKQPSVGSNAEPVIGPIAGSITGPIAGSITEPIVGTSTGPITGSVNESITGSVNGPITGSVTGPITGSVTGAITGSVVESFPVNLNTVQVNQVEENNQVLMENIKVDQQINNTQLLNDVPQLSIDTDSQLAESVLNNTYIFGEDGDIMFYVLDNNPIPGY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01005513;
90% Identity
iTF_01004554;
80% Identity
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