Mita019389.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Metalampra italica
Gene Symbol
-
Assembly
GCA_949699065.1
Location
OX452998.1:706213-714837[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 0.0026 6.4 6.8 0.1 30 58 331 359 311 417 0.66
2 3 0.0078 19 5.2 0.0 29 58 508 537 496 582 0.85
3 3 0.0071 18 5.4 0.0 30 58 604 632 591 688 0.84

Sequence Information

Coding Sequence
ATGCCAGCTAATACAAAGTTCCAAAACATCCAACTGACCCCCATAAAGATGCTATCGGTGTCTCCAATCGATATGAAAACATCCCTGGTATCCGCCCTGCATACACCATCACATCTCATGCGGCCACTTCAGCAACACGTCAACTTGGAATCCAATAACAATGAGACCAACATTTCCCTAAGTAGTGACCATTACTATCCAAAACCAATAACTGTTAGCGTCAAATCGGAAACAGCCAATCAGGCAGAGTGCGAAACTACAAgagatataaaaatagaacTCGAGAGCTGTTCTGATGTAGAAATAGAAGTACCATTAATAGAATTCAAAGGGGAAACATCTATACAGAAACTACCAAAAGATATTACGATCTATCCCGTGCATCAAAGGTACGAGGGGAAAGTGAAAATTGTAACGCTGACTAAGGAAGAGCTGATGTTAGAGAGAGACAAGGAGAGGCTGGGGGAAAAGTATTTGAAGCTTCCTTATAAATGTGAGACTTGTGTAACAGCGTTTGACCACGAAATTCTGTTAAAAAACCATATGATGAAACGACATACTTTGAAACCCGGCACAAGTGTCTGTGAGATTTGCAAGTGCGTGTTTGGATCCAGCCCCTACGCGTGTAAGGAACACATCAAGCGGCATTTTGCGAGGTATGATTGCTTGGAGTGCGGCAAGCGGTACAACAGCCTGCTGGGCGCCACGACGCACTGCGCCCAGGTCCACGGCAGCATCGCCACCAGCTACCAGTGCCAAGAGTGCGACTTCACCACGCAACGATACCGGCAGTACCGCTACCACAAACAGAAGCACCGGCAGCGCGTGCCGTGCCCGCAGTGCGACAAGAAGTTCGTCTCCACCTCCGGCCTCAAGACGCACTTGTTAGTGACCCATAGGGCGTCCGACCGCGTGTACACGTGCGAGAGCTGCGGCAAGGAGTTCCGCCATAAGTCCGCCGCGAGCAATCACCAGCGGTCCGCGCACAGCGGCCTTGGCACCGCGTACTGCGCGCCGTGCAACGCGCACTTCCGCACCGAGCAGGGGCTCTCCTACCACCTCAAGTATCACTCCAAGCATCTAGACGACAGCGCCAAGAGCCAGCACCAACGGTCCGCGCACAGCGGCCTCGGCACCGCGTACTGCGCGCCGTGCGACGCGCACTTCCGCACCGAGCAGGGGCTCTCCTACCACCTCAAGTATCACTCCAAGCATCTAGACGACAGCGCCAAGAGAGGTGAGCACTCACCAAGCCAGCACCAACGGTCTGCGTACTGCGCGCGGTGCAACGCGTACTTCCGCACCCAGCAGGGGCTCTCCTACCACCTCAAGTATCACTCCAAGCATCTAGACGACATCGCCAAGAGAGGTGAGCACTCACCAAGCCAGCACCAACGGTCTGCGTACTGCGCGCGGTGCAACGCGTACTTCCGCACCCAGCAGGGGCTCTCCTACCACCTCAAGTATCACTCCAAGCATCTAGACGACATCGCCAAGAGCCAGCACCAGCGGTCCGCGCACAGCGGCCTCGGCACCGCGTACTGCGCGCCGTGCGACGCGCACTTCCGCACCGAGCAGGGGCTCTCCTACCACCTCAAGTATCACTCCAAGCATCTAGACGACAGCGCCAAGAGAGGTGAGCACTCACCAAGCCAGCACCAACGGTCTGCGTACTGCGCGCGGTGCAACGCGTACTTCCGCACCCAGCAGGGGCTCTCCTACCACCTCAAGTATCACTCCAAGCATCTAGACGACATCGCCAAGAGAGGTGAGCACTCACCAAGCCAGCACCAGCGGTCCGCGCACAGCGGCCTCGGCACCGCGTACTGCGCGCCGTGCGACGCGCACTTCCGCACCGAGCAGGGGCTCTCCTACCACCTCAAGTATCACTCCAAGCATCTAGACGACATCGCCAAGAGGTTCGAGTGCGACTACTGCGGCAAGAGGTACCCGCTCAAGTGCAGCCTCCTGGACCACATCAACGGCATGCACCTCAAGCGGTACTGGTACTCCTGCAACCAGTGCGACGAGAAGTTCCTGTGGAAAACGTATCTGAGGAGGCACAAGGTCACGACGCACAAGAAGGGCGGAGCGCCCCGAGACAAGATCTGCCAGCACTGCGGCAAGGGCTTCACTACCAACCGCATCCTGGAAGCGCACATCCGCACGCACACGGGCGAGCGGCCGCTGGAGTGCGCGCACTGCCCCGCCACCTTCGCGCACCCCGCCGCCAGGTACAACCACATCAAGCTGGTTCACAAACGCAAGAGACCCGCCGCCGTGTGA
Protein Sequence
MPANTKFQNIQLTPIKMLSVSPIDMKTSLVSALHTPSHLMRPLQQHVNLESNNNETNISLSSDHYYPKPITVSVKSETANQAECETTRDIKIELESCSDVEIEVPLIEFKGETSIQKLPKDITIYPVHQRYEGKVKIVTLTKEELMLERDKERLGEKYLKLPYKCETCVTAFDHEILLKNHMMKRHTLKPGTSVCEICKCVFGSSPYACKEHIKRHFARYDCLECGKRYNSLLGATTHCAQVHGSIATSYQCQECDFTTQRYRQYRYHKQKHRQRVPCPQCDKKFVSTSGLKTHLLVTHRASDRVYTCESCGKEFRHKSAASNHQRSAHSGLGTAYCAPCNAHFRTEQGLSYHLKYHSKHLDDSAKSQHQRSAHSGLGTAYCAPCDAHFRTEQGLSYHLKYHSKHLDDSAKRGEHSPSQHQRSAYCARCNAYFRTQQGLSYHLKYHSKHLDDIAKRGEHSPSQHQRSAYCARCNAYFRTQQGLSYHLKYHSKHLDDIAKSQHQRSAHSGLGTAYCAPCDAHFRTEQGLSYHLKYHSKHLDDSAKRGEHSPSQHQRSAYCARCNAYFRTQQGLSYHLKYHSKHLDDIAKRGEHSPSQHQRSAHSGLGTAYCAPCDAHFRTEQGLSYHLKYHSKHLDDIAKRFECDYCGKRYPLKCSLLDHINGMHLKRYWYSCNQCDEKFLWKTYLRRHKVTTHKKGGAPRDKICQHCGKGFTTNRILEAHIRTHTGERPLECAHCPATFAHPAARYNHIKLVHKRKRPAAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00994690;
90% Identity
iTF_00994690;
80% Identity
iTF_00994690;