Mdia006231.1
Basic Information
- Insect
- Meloe dianella
- Gene Symbol
- LZTR1
- Assembly
- GCA_028455855.1
- Location
- JAPTHL010000001.1:391691-394258[+]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 1.2e-11 2.3e-09 37.0 0.7 1 80 356 458 356 507 0.82 2 4 0.0015 0.27 11.0 0.2 78 108 507 537 498 539 0.86 3 4 2.5e-18 4.7e-16 58.5 0.0 10 97 609 696 603 711 0.83 4 4 4.5 8.3e+02 -0.2 0.0 76 101 709 734 705 742 0.78
Sequence Information
- Coding Sequence
- ATGAGTAGTTTAACAATATTGGATGATGCTGCCCTTTATGATAATGCATTAACATTAGAGATAGGTCCATTGGAGACGGTGCATCGTTGGCGGCGTATGCCCGAATGTGATGAATTCGTTGGAGCTAGACGTAGTAAACATACTGTAGTGGCATATAAAGGTGCAATCTATGTATTTGGTGGTGATAATGGTAAAAGTATGTTGAATGATCTGTTAAGATTTGATGTGAAAGAGAAATCATGGGGACGAGCCTTTGCTAATGGTACACCACCAGCATCACGTTACCACCATTCAGCTGTTGTATATAAAAATTCAATGTTTGTATTTGGTGGTTATACAGGCGATATACATTCAAATTCAAATTTAACAAATAAAAATGATTTATTCGAATATAAATTCCATTCAGGACAATGGATTGAATGGAGATTTCATGGTATCACACCTGAACCACGATCAGCACATGGTGCAGCTGTTTATGATAATAAATTATGGATATTTGCTGGTTATGATGGCAATGCCCGTTTGAATGATATGTGGACAATTTCATTATCTGGTGATAGTCGGAATTGGATTAAAATCCAACAACAAGGTGAATGTCCACCGACTTGTTGTAATTTCCCTGTAACAGTCGCCAGAGAACGAATGTATGTTTTTAGTGGACAAAGTGGAGCTCAAATAACAAATTCTCTATTCCAATTCAATTTCACAACACATACTTGGACACGTATCAATACTGATCATATAATTCGTGGAACACCACCACCACCGGCACGTCGTTATGGACATACAATGGTAGCATTTGGTCGTCATTTATATGTGTTTGGTGGTGCTGCTGATAGTACATTATCAAATGATTTGCATTGTTTCGATTTAGATACACAAACATGGTCGACAATTCTACCAGCACCAGATAGTTTCGTACCATCTGGACGTTTATTTCATGCAGCCGCTGTTGTAGATGATGCAATGTTTGTATTTGGTGGTACAATTGATAATAATGTACGTAGTGGCGAAATGTATCGCTTTCAATTCTCATGTTATCCAAAATGTACATTGCACGATGATTTTGGTAAATTATTGAAAACAAATGAATTCCACGATGTGCAATTTCTTGTTGGTATTGAAAAGAAGAAGATTTATGGACATATGGCAATTATAGCATCACGATCATCACATTTACGTGCACTATTGAAAAAGAACAAACAGAAACGTGATAATCATTTAGAGAAATTATTTGGTACAGTTAATGTGCCATTTAAGGAAGTACCATTAGTTGAAATTGAATTTCCCGATGCTAATCCGGAAGCGTTCcaattaatcttagattatatttatatggattgtattgatccaacaacaaagaaaaatgatgatgatgatgatgatgatgatgatcgtgataatttaacattaaTTTCAGCTGAACATGTTTTACGTATGATGGATGTATATCGTTTAGCTGTTGAATTTGGTATTGTACGTCTTGATCATTTGTGTGTACAATATTTGAATTCGGCAATAAATAAAAATAATGTATTAGATGTATTAGAAGCGGCGCACAATTTAAAATTGAATGTTATTAAAGATCATTGTTTAAAATTCATTATAAAAGATACAAATTATAATGATATTGTAATGTCAACGAAATTCGAAACGTTAAGTAGCCGATTGATTGTTGAAATTATACGTTTGAAACAAACATCAAATGGTTGTAAAACAACCATTATGGAACATTCAAATGTGGAATTAGGTGGTGGTGGTGGTGGTGGTGGTACAACATTAGAACAAGATATGGCAGCATTTCTCGTTTGTAATGGTGCACCATTTTATGATGTTGATTTAATATTAGATGGCCATATAATACCAGCACATAAAGCAATATTGGCAGCACGTAGTGGTTATTTTGAAGCATTATTCCGTTCATTTATGCCGACCGATTCAAAAGTTAAGATACAAATTGGCGAAATGATACCATCATTGCAATCATTCCATTCATTATTGCGTTTCATTTATTGTGGTGACATTCATATGCCACCAGAGGATTCATTATATTTATTTTCAGCACCATCATTTTATAGTTTTACAAATAATCGTTTACAGGCATTTTGTAAACAAAATTTAGAAATGAATGTATCATTCGAGAATGTCATACAAATATTGGAAGCGGCCGATGGTATGCAAGCAACTGATATGAAAAAATATGCATTAGATTTAATTGTACATCATTTTACGAAAGTGGCAAAATTACCAAGACTGAGATCATTAAGTAAAGAATTAATTTTAGATATTTTAATGGCATTAGCCAATGATATGAGTGAATCGAAATTATGCCAAGATGTATCATCAGCCAGTCTATCTACTGAAAGTAATAATTAA
- Protein Sequence
- MSSLTILDDAALYDNALTLEIGPLETVHRWRRMPECDEFVGARRSKHTVVAYKGAIYVFGGDNGKSMLNDLLRFDVKEKSWGRAFANGTPPASRYHHSAVVYKNSMFVFGGYTGDIHSNSNLTNKNDLFEYKFHSGQWIEWRFHGITPEPRSAHGAAVYDNKLWIFAGYDGNARLNDMWTISLSGDSRNWIKIQQQGECPPTCCNFPVTVARERMYVFSGQSGAQITNSLFQFNFTTHTWTRINTDHIIRGTPPPPARRYGHTMVAFGRHLYVFGGAADSTLSNDLHCFDLDTQTWSTILPAPDSFVPSGRLFHAAAVVDDAMFVFGGTIDNNVRSGEMYRFQFSCYPKCTLHDDFGKLLKTNEFHDVQFLVGIEKKKIYGHMAIIASRSSHLRALLKKNKQKRDNHLEKLFGTVNVPFKEVPLVEIEFPDANPEAFQLILDYIYMDCIDPTTKKNDDDDDDDDDRDNLTLISAEHVLRMMDVYRLAVEFGIVRLDHLCVQYLNSAINKNNVLDVLEAAHNLKLNVIKDHCLKFIIKDTNYNDIVMSTKFETLSSRLIVEIIRLKQTSNGCKTTIMEHSNVELGGGGGGGGTTLEQDMAAFLVCNGAPFYDVDLILDGHIIPAHKAILAARSGYFEALFRSFMPTDSKVKIQIGEMIPSLQSFHSLLRFIYCGDIHMPPEDSLYLFSAPSFYSFTNNRLQAFCKQNLEMNVSFENVIQILEAADGMQATDMKKYALDLIVHHFTKVAKLPRLRSLSKELILDILMALANDMSESKLCQDVSSASLSTESNN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00753081;
- 90% Identity
- iTF_01566332;
- 80% Identity
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