Mbic005566.2
Basic Information
- Insect
- Melipona bicolor
- Gene Symbol
- -
- Assembly
- GCA_030673865.1
- Location
- JAHYIQ010000004.1:2711080-2713717[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 5.6 6.1e+02 1.8 0.2 1 10 293 302 293 308 0.86 2 15 0.0093 1 10.5 1.4 1 23 323 346 323 346 0.92 3 15 0.038 4.2 8.6 1.2 1 22 352 373 352 376 0.87 4 15 0.089 9.8 7.4 5.3 1 23 458 480 458 480 0.93 5 15 0.0081 0.89 10.7 0.5 1 23 487 510 487 510 0.91 6 15 0.00098 0.11 13.6 3.1 1 23 516 538 516 538 0.97 7 15 8.8e-05 0.0097 16.9 2.3 1 23 544 566 544 566 0.99 8 15 2.7e-06 0.0003 21.6 2.2 1 23 572 594 572 594 0.98 9 15 0.026 2.8 9.1 0.1 1 23 607 630 607 630 0.93 10 15 0.00024 0.027 15.5 3.3 1 23 646 669 646 669 0.96 11 15 0.0001 0.011 16.7 0.5 1 23 677 700 677 700 0.98 12 15 0.00064 0.071 14.2 0.7 1 23 706 728 706 728 0.97 13 15 0.0005 0.055 14.5 5.2 1 23 734 756 734 756 0.98 14 15 4.4e-06 0.00049 21.0 1.6 1 23 762 785 762 785 0.98 15 15 0.00078 0.086 13.9 0.9 2 23 791 812 791 812 0.97
Sequence Information
- Coding Sequence
- ATGGATGCTTCAAAAGATGCATTAATATGTCGTTTATGTGGTGTAAATCTTACAGAAGGAAAGCATGAAAGTATCTTTGAAGGTTCGACagatttaatacataaaataaaggaaacaTTACCAATAACAataTCTATTGATGATAGTGGCTCAAAGTATGTATGTTTATCATGTTATgacaaaatcattttttactACAAATTTATTCAAGAGGTATTAGAGTATTCTAAAAGATTGGAAAAGACATCgcaaataaaatctttttttaatctttctaaAGAAGTAACAGACTTCTCTCAGATACATAGTGATGCTGTGTATACATGTCCAAACTGTAATGTagatttaatgattttattagTTAGTAATTCTCAAGGCTGTGATTACACCTTCCAAATCTCATTAGCTATGGTAAAtcattctgaaaaaaaatatattgcaaaagAAAAGTGTATAAACATACATAAAGATATactacattttaataatatacatataaaacaaGGAAACAAAACAACAATTGATGAAGGTATTGAAAATACACCTACTGAAGTAAGTGTAACATTACCTGTTTtacaagaagaaaattttaactgtattaatgaattatctggcaaagaaaaattaaaaattgagaaagaattaagaaaaaattttaaagaagaaacatcGCATGTATCTAgtaatttacttaattatGGTTATGATTCTACAGATCCATTAGTGAAAAATGAACCTGAAAGTGATAATACTTATTGGATAGATAGTGAGACTGATTACAAAAGTGAGAAAGATACATGTGTAACTAAATCGCAAGATATGTTTGAAAAAGATGATATACAAgatgaaaatgatatatataaatcttgtTTAaagtatgtatgtaaattatgTGGAGCCCGTTATCTTTcacatttaaaatatgaatttcacaCGGAGAGGCATAAATTAggtaaaatagataaatatgaATGTACTCTATGTGATAAAGAAAcaagtaatgaaaatttattatggGATCATTATTTCCACACACACAAAAGTTTACAACGTTATATTTGTATAGAATGTGgcaaattatttacaaaacgaTCTAGACTAAATGGgcatcaaaaaaattataaacattctGGTGTGAAACAAATACAAGTTGGTACTAGTGAAGATACTATCAGTGAAGATGTCATACAAAAAGCTATAGCAACAACAAAACAGGAAAAAGTATCTATAAATTGTAATCTTTGTGGCAAATTGATCTCAGATTTAGATCCGGATGCTATTAATGATTTAGTGACATGTGTTACTTGTGAAGATTCTACACTTTCTTTGATGATAGATGGAAATGAGACAAAAGTCATTTCGCCGCGCCAATATCATTGTTCTAAATGTCCTAAACATTtcgtaagaaaagaaagattagaatttcatgaaatgagacataatgaaaatatgaatgaatTTATCTGTAGCACTTGTGGAAAAGATTTTAGAGCAGAAAATTCTTTATATGAACATTATCTTTTTGTTCATAAAGGAGCAAGACCTCACATTTGTGAATTATGTGGCAAGTCATTTCAGTTGAAAGCTAGATTAAAAGAACATCATCGAATTCATACAGGAGAAAGGCCGTATCAATGTGATATCTGTGGTCAACGATGTAGAACTACAAATGCTTTGAAACTTCacagaaaaattcatttttcttacaATAGATACActtgtaatatatgtaataaatcaTTTAGTAAAAAGCAGAATATGAATGAACATTTAGAAAAGCATtggaaaaatgataaaagtgTAACATTACCACAATTATTTACATGTCCAATTTGTATAGAAGATTTTCCAACATATCGCATGTTAAAATATCACATGGTAGAAGatcatgaaataaataatcaggatccaattttaacaaaacaaaaaccATGGTACGAATGTGCAGAATGTCatgagaaatttaaacatcAGATGTCTTTAAAAGCACATAAAGAGAGAATACATGAGGGAAGAGTAAATCCTATCTATCAATGTGACATATGTAATGCTACATATAGAGTAAAACAACTTTTAGTAAATCACATTAAAAGTAAACATAATGGCGAAAGACGTTATAAATGTGCACAGTGTGAAAAAGGATTTAATGACACTAAATCTTTATATAATCATGTATTATTACACACTGGAAAAAAACCATTTGTCTGTGAATATTGTAACATGAGTTTCAGAAGAAAAGATTCCCGAGATCATCATCGCAGAAAACATACTGGTGAACAACCTTATCAATGTCCGGATTGTGGGGAATCCTTTTCTACTTACAATAATCGATCTAAAcatcgaaaaaaagaacatgGAGAAGGAGATCCTGAATGCCCAGAGTGTggagaaaaatgtaacaatcaacaagaaattagaatacacttaaataaacatttgggagaaaaattaaaaaaattacaaaatgtagAATCTGAgaagatataa
- Protein Sequence
- MDASKDALICRLCGVNLTEGKHESIFEGSTDLIHKIKETLPITISIDDSGSKYVCLSCYDKIIFYYKFIQEVLEYSKRLEKTSQIKSFFNLSKEVTDFSQIHSDAVYTCPNCNVDLMILLVSNSQGCDYTFQISLAMVNHSEKKYIAKEKCINIHKDILHFNNIHIKQGNKTTIDEGIENTPTEVSVTLPVLQEENFNCINELSGKEKLKIEKELRKNFKEETSHVSSNLLNYGYDSTDPLVKNEPESDNTYWIDSETDYKSEKDTCVTKSQDMFEKDDIQDENDIYKSCLKYVCKLCGARYLSHLKYEFHTERHKLGKIDKYECTLCDKETSNENLLWDHYFHTHKSLQRYICIECGKLFTKRSRLNGHQKNYKHSGVKQIQVGTSEDTISEDVIQKAIATTKQEKVSINCNLCGKLISDLDPDAINDLVTCVTCEDSTLSLMIDGNETKVISPRQYHCSKCPKHFVRKERLEFHEMRHNENMNEFICSTCGKDFRAENSLYEHYLFVHKGARPHICELCGKSFQLKARLKEHHRIHTGERPYQCDICGQRCRTTNALKLHRKIHFSYNRYTCNICNKSFSKKQNMNEHLEKHWKNDKSVTLPQLFTCPICIEDFPTYRMLKYHMVEDHEINNQDPILTKQKPWYECAECHEKFKHQMSLKAHKERIHEGRVNPIYQCDICNATYRVKQLLVNHIKSKHNGERRYKCAQCEKGFNDTKSLYNHVLLHTGKKPFVCEYCNMSFRRKDSRDHHRRKHTGEQPYQCPDCGESFSTYNNRSKHRKKEHGEGDPECPECGEKCNNQQEIRIHLNKHLGEKLKKLQNVESEKI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01123228;
- 90% Identity
- iTF_00982458; iTF_01419152; iTF_00873955; iTF_01418516; iTF_01420438; iTF_01419801; iTF_01421085;
- 80% Identity
- -