Mbic022626.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Melipona bicolor
Gene Symbol
zfy1
Assembly
GCA_030673865.1
Location
JAHYIQ010000053.1:213901-219297[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 9 9.9e+02 1.1 1.8 2 22 308 328 308 328 0.93
2 24 8.6e-07 9.5e-05 23.2 3.2 1 23 338 360 338 360 0.99
3 24 2.8e-06 0.0003 21.6 1.1 1 23 366 389 366 389 0.95
4 24 1.3e-05 0.0014 19.5 1.2 1 23 395 417 395 417 0.99
5 24 0.59 66 4.8 2.2 1 11 423 433 423 434 0.93
6 24 0.33 36 5.6 5.3 1 20 505 524 505 524 0.97
7 24 0.0012 0.14 13.3 0.4 1 23 565 588 565 588 0.94
8 24 0.00038 0.042 14.9 1.7 1 23 620 642 620 642 0.98
9 24 6.1e-05 0.0068 17.4 1.6 1 23 648 671 648 671 0.96
10 24 4.5e-05 0.005 17.8 0.3 1 23 677 699 677 699 0.98
11 24 3.9e-07 4.3e-05 24.3 0.9 1 23 705 727 705 727 0.98
12 24 6.2e-06 0.00068 20.5 1.5 1 23 733 755 733 755 0.99
13 24 0.0002 0.022 15.8 2.3 1 23 761 783 761 783 0.96
14 24 4.4e-05 0.0049 17.8 1.3 2 23 790 812 789 812 0.96
15 24 0.0077 0.85 10.8 0.1 2 23 843 865 842 865 0.95
16 24 5.1 5.6e+02 1.9 0.7 1 13 870 882 870 893 0.81
17 24 1.6e-06 0.00018 22.3 2.8 1 23 930 952 930 952 0.99
18 24 0.00098 0.11 13.6 1.5 1 23 980 1002 980 1002 0.99
19 24 0.00015 0.016 16.2 0.7 2 23 1009 1031 1008 1031 0.94
20 24 0.00049 0.054 14.5 0.0 1 23 1037 1059 1037 1059 0.97
21 24 0.0012 0.13 13.3 1.2 1 23 1065 1087 1065 1087 0.97
22 24 0.0036 0.4 11.8 9.9 1 23 1093 1115 1093 1115 0.97
23 24 5.7e-05 0.0063 17.5 0.0 1 23 1121 1143 1121 1143 0.96
24 24 0.0074 0.82 10.8 3.0 5 23 1152 1170 1150 1171 0.94

Sequence Information

Coding Sequence
ATGGAATCTGAAAGTTCTGTCATGTTGGAATCATGCGGGGaacattcaattttaattcaaacagTAAAAGATATGGTGAATGAGAATACGCGTGCTGAGTTAGAAAATGAGGAAGAAAGATTTTTCGTCGTAACAGATGTTCAGGATGAACAACAAAATATGATAGAAGTATCAAACGAAGAATCGACAGTAACACAGTCCGATGATCAATTTTCATGGTCTAATTTATGCAGATTATGTGCTAATGTTAATGATCATTTAATTCCAATATTTGATGGAGAAGGTCTACAACATGActtgtgtaataaaatacataaatatctaCCAATATGTGTATCTGAAAATGATGCACTCCCGTTGCAATTATGTTATCATTGTGCTGCTACATTATTAGCATGGCATGAACTATCGGAAGGATGCCTGAATGCAGAAAGAAGATTATTGGAGATGCAAGATGCTTTGCAAGAAAAGCAGGGATCAGAAGGATTAGAAACTTCTATACAGGATACATCTGTATCTAATATAACAGAATCACTTGTAAGTCAAGAAACTGTTGAAAAGGATGAAGTCTCTGGGAATTCAACTATTAATGATTCCGGCAGGTCCAGTAGTATGCGAACACCGTTTAAGATGTTCCTAGATATGCAGAATGTCTTTCGGAAGCCACACAGAAAAAAGTGCCAGCTCCAAGAAAGAAAGCCTACAGACAATGGAGATTGCGAATCAGTGTGGATTACCGTCATGAATTCGACGCTTGATCAGCCTGCTATAATGTCTGATCAACTGCAAGACAATGATATCACTATAAAGGAAGAGGTGTCTCAAATGTATAATTCAGACAATatcgagaaattgaaactgGACGATGGGAAGCCAACAGATTCTCCAAATACAAAAAATGGAAGTAAAAAGGCGAGAGGAAAATGTAAAGCTTGTTCGAACAATTCGAAAAGCTCGAGCGATCTTTGCGGACATGTGAAGACTAAAGCTAACATTGACGTTCAAGAGTCTTACCAATGCGTCGAATGtggaaaatgtttcaagttGAAGGATTCCTTTCTCAGACACATGAGGATACATACGGATGAAAGGCCGTTCACTTGTCACGTGTGTGGGAAACAATTTAGGGATTCCGGCGGTCTTTCTAGACATTTAAAGGACGTACACGCAAAACTAAAGAATTTCACGTGTGACATATGCAATAAGTCTTTCGCATCGAAAGCTACGAGAGAGGATCATCGTCGAACTCATACCGGCGAGAGACCCTATGTATGTGACTCGTGTGGAAAGACGTTTAAgTTTGGTCTACCTCAGAAGAGATCCTTCGCGGCATATTGCTCGTGGCAGCAAACATTCAATGAGACGAACTTgaaagaaagtagaaaagaACGAATTAGCGACAATGAGGATAATTCACTCGATAGTTTTTACAATGCAGATCTAGATATGAGAAAAATGGTGAAAGTAATACTACCTCctttaaatgaaattgctACTTCATTGAAAAACCAATACACGTGCAAACACTGTTGTCGTATCTTCGAAGGGAAATACCACTTGACGCAACATATACCTAAATGTAAAAGCGTGGCTGAAAGCTCCACTGAATGCAGCACATCAAATGCAGAGGATGCAAACAAAGTGGACAAAGATCGAGAAGATTTGAAATGTAAGAGAAACAAACTTGGAACATATCCGTGCATGTACTGCGACTATACGGTGAAGCAAAAGAAACTGTTGGAGTTACATTTATTGGAATCGCACGCGGAGTTTGCCAGAAAGAAGGATAGAAAGTTGAAATGTGCCGACAGAGAAATGGTGATGCGCGCTAAAATGGAGGTCGACGGGAAGATCTATTATCATTGCAACGAGTGTGGGAAGAATCTCTATTCGCCTTACACGTTCTTCTGGCACGTGCGTATACACACCGGAGAACGATCGTACACTTGTCATCTTTGTGGCAAACAGTTTCGCATAAATCAAGGACTGGCGAGACACTTGCGTGACACGCACGCCGGCATAAAGAACTTTCCGTGCGACGTTTGCGGCCGAATgttttcgacgaaacgaagcgCGGAGGATCACAAACGCATCCACACCGGCGAACGACCGTACATTTGCAACATTTGCGGGAAGTCGTTCAAGCAGAAAGCCTCTCTGTTCGTGCACAATCGCAGTCACTCGGACGTGTTCCCctttaaatgtaattactGCGATCAGAACTTTCGGACGAGGCCGTCGCTCGCGTTACACATAAAGAAACACACCGGCGAGAAACCGCACGCTTGCGATATATGCAGCCGACGTTTCCGTATAAAATACGAGCTGAAACGTCACCGTTTGATTCATTTCGACGATAAACCATGGCAGTGCACAGAGTGCAACCTCTCGTTCCGACAGAAACGCTATTTAGTTAATCATAGGAAAGTTAATCACAATCCGCGGTGGAAGATCGAGTCTGACACTGTTATGCAAATATCGACGGTCGAAAGCGAGAGTACGAACGTCGAGGAGATAGAGTACATCCAGTGTGCTCAATGCAACGTTGTCTTCGTGAACATGAAGTACTTCATAGATCACATGAACAACGAGCACGAGGCTCAAATGCACTATTGTCAGTATTGCAAACTGGTGTATCGTGGCCAAGATAAGGATTTTGAAGATCACGTGTCGATGCATGATATCAATTGCAAAGTAAAAGAGGATGAAAGCTTGGAATgcacgaacgaaacgagaagagaagaTAAAGATGAGTTCGATCGGCAGATCATTGAGAAGCCTCTGTGTTACACTTGCAACTTGTGCgagagaaatttcacaaaaaagtCCGAATTGAAGAAGCACATAAACCGACATTCGGATGTCAATCCGATCGAGAATCCAGACGAGACAGAGCTTGTAAATAAAGCGAAGCAAATAATCAATGACCGTGTTTCTTACAAGTGCGATATGTGTAAAAAGATCATATTCACGAAACGGGGGTTTCTACGCCACATTCGCGTGCATTCTGACAAACGACCTTGCAAGTGCGATCTATGCGGaaaatcgtatcgtatcgAGCAGGATTTAGCCAGACACATACGAGACGTTCACGAGGGATTGAAAAAATACGCCTGCGACATCTGTGGCCGGGCATTTGCGAACAAAGGAGCAAAAGACGATCATCGGAGGATTCACACCGGTGAACGGCCGTACGCGTGCGAACACTGTCCAAAAATGTTTCGAACTCTGAATTCTATTTACATTCACAATCGCGTACACACGGATTATAAACCTCATAAATGCACGTATTGCGGGAAACATTTCAGAAGCAGGCAGAGGCTGACTCATCATGAAACCACGCATACAGGTATCAAACCTTTTGCCTGTGAAGTCTGTGGTAAAACGTTCTCTGTCAAAGGAGAGGTCGTGCGACATCGCGCTATACATAACGAAGAGAAACCTTTCGACTGTAAATGTGGAATGAAATTCGGCCAGAAGAGATACCTAAGAAATCATATAAGACAACATCACAAGGAAGCATCTTCGTGGTTATTAGCAGAATTATTGGGAAGTAGTAATTGA
Protein Sequence
MESESSVMLESCGEHSILIQTVKDMVNENTRAELENEEERFFVVTDVQDEQQNMIEVSNEESTVTQSDDQFSWSNLCRLCANVNDHLIPIFDGEGLQHDLCNKIHKYLPICVSENDALPLQLCYHCAATLLAWHELSEGCLNAERRLLEMQDALQEKQGSEGLETSIQDTSVSNITESLVSQETVEKDEVSGNSTINDSGRSSSMRTPFKMFLDMQNVFRKPHRKKCQLQERKPTDNGDCESVWITVMNSTLDQPAIMSDQLQDNDITIKEEVSQMYNSDNIEKLKLDDGKPTDSPNTKNGSKKARGKCKACSNNSKSSSDLCGHVKTKANIDVQESYQCVECGKCFKLKDSFLRHMRIHTDERPFTCHVCGKQFRDSGGLSRHLKDVHAKLKNFTCDICNKSFASKATREDHRRTHTGERPYVCDSCGKTFKFGLPQKRSFAAYCSWQQTFNETNLKESRKERISDNEDNSLDSFYNADLDMRKMVKVILPPLNEIATSLKNQYTCKHCCRIFEGKYHLTQHIPKCKSVAESSTECSTSNAEDANKVDKDREDLKCKRNKLGTYPCMYCDYTVKQKKLLELHLLESHAEFARKKDRKLKCADREMVMRAKMEVDGKIYYHCNECGKNLYSPYTFFWHVRIHTGERSYTCHLCGKQFRINQGLARHLRDTHAGIKNFPCDVCGRMFSTKRSAEDHKRIHTGERPYICNICGKSFKQKASLFVHNRSHSDVFPFKCNYCDQNFRTRPSLALHIKKHTGEKPHACDICSRRFRIKYELKRHRLIHFDDKPWQCTECNLSFRQKRYLVNHRKVNHNPRWKIESDTVMQISTVESESTNVEEIEYIQCAQCNVVFVNMKYFIDHMNNEHEAQMHYCQYCKLVYRGQDKDFEDHVSMHDINCKVKEDESLECTNETRREDKDEFDRQIIEKPLCYTCNLCERNFTKKSELKKHINRHSDVNPIENPDETELVNKAKQIINDRVSYKCDMCKKIIFTKRGFLRHIRVHSDKRPCKCDLCGKSYRIEQDLARHIRDVHEGLKKYACDICGRAFANKGAKDDHRRIHTGERPYACEHCPKMFRTLNSIYIHNRVHTDYKPHKCTYCGKHFRSRQRLTHHETTHTGIKPFACEVCGKTFSVKGEVVRHRAIHNEEKPFDCKCGMKFGQKRYLRNHIRQHHKEASSWLLAELLGSSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00982424;
90% Identity
iTF_00983720;
80% Identity
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