Mbee002083.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Melipona beecheii
Gene Symbol
Baz2b
Assembly
GCA_032399605.1
Location
JAUCMO010000078.1:3203158-3227163[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 8.1e-22 2.3e-18 65.7 0.0 4 76 534 606 531 607 0.94

Sequence Information

Coding Sequence
ATGCCGGGCGGATATGGGTTGGGGGCTCATCATTTGCCGTCGGCTTACGCGATCCTGGGCCGTGGAGGCTCCGCTCCCGGATTCGGGGGCCACACGCCAGCTTCCGCTCCGCCGCCACCCCCGTACTCTCACAGCAGCCTTGGTACTCTGAGCGTAGCTGCCAGTCAGGCTGCGAGTTTAGGTATCAATCCCGCTAGCGCAGCATGGTGGACGATGGCCTCACATCTGGCGGCACAGGACTACCTCGCGAGGTTACAGGGAGCGGCAGGACTGCCCGGATTTCCGCCTGGCGCCGAGAGCCTTCTGCCACCTTATCCCGCTTCTCTTCTTAATCCCCCGTCCCTATCGTCCCACAAGTCCAGTAAGTCTAAGTCAAGCAAGAGTCACAAGACGCCAgcgagcagcagcagcagcagcagcagctcgACGACGCCGAGTATGACGAGCAGCAGTTTACCGGTCTCGACTCAAGCACCAGTCACGTCCTCTCATCACAGCACGTCGGCCAGCAGCACGCCGAATTCGCAAACGAACGTTGTCAGCGACCCGAGCAGTATATTAGGAGGTGTACGGCTGCCGCCTGATACGGAGATTATCAAGTACACGTCGAGCATAGTCGGTCCAAAGGTTCCTGGCACGACGAACCGCGGCAGGAAGAAAACTATATCCTTGGACACGCCTAGCGTGAGCGTGCATCCGCCGCCTGTGCCAGCTCTCAGCGCTCATCAAACAAACACCACGACGTCTTCGTTGATGATGGAACCGAGAAAGTATAATCGCACCGGGaCCGAGTCGAACGACTACAGGGAGTCGGTGGATCGCGTGGAAGTGATCAAACTGCCGGCACACTCGACAAACGGCTCTGTCCTACCGGCGCCAACGTCCTACACGACGACCACTAACGCGAGCAATTCGAACGATTCGGACGCGCCTCTGAATCTCTCGCTGAAGCCCGCGACGACGAGCAGTAGCTCGCCGATTTCCGGCAGCCAGCCGCTCAGCCAGCTTAGTAATTTAAGTCAATCGTTACTCGCCTCCGATCGAACCTCGAGAAGAAAACCGGGACCGAAGCCCCGAAGAGTACCGCAGAACTCCGTGCCGGTGCCAGCGTCGCCAAGCACATCGTTGGCGCAGATGTTCGCCGCGGCGGATTCGCCTCAACGACCGAGCAGCGGAAGCGAGGAGAGCGAGAGCGCGAGCACGACCCACCACAAGGACGGTCGGCCGAGAAACTTGGGCCGCGGAGTGTCGAAACCGAAGAAGAACACGGTGGCCTCGTTGCTAGCTCAAAGCAGAGCTCTGGGGATCAAACCGACGCCCACGTTGGACCCTAGCGTGCCATTGTCTCATCAGGTCTCGTTGCTGAGGTCGAATATTCTGGCTGCTCAGCTACATGGCACTTCCACTGGTCAGATCGACGACAAGAATCAGCGGTCTTTGCAGGAGAAGATGAAGAACAAGCTGCTGGAGGTGTCCGGCGAGGAGAGCAACATGGACGTGACGAGCGAGAGCGGCAGCAACACGGACGTCGTGACGGACACCGACGACGACAACGCGGACGGCGTATCTAGCGCCAAGAGAAGAAAGATGAAGCCCAGCGAGAGGGATCTCCAGGTGCCGCTCGAGCGTGGTTGGAAGCGAGAAATCGTCATCAAAGGATTAGGGAAGTCGGGAGTGATAAAGGGTGACGTGTCTTATTACAGTCCTTGTGGAAAGACGTTCAGAAGCAGTCCGGATTTGGCGAAGTTTTTGGAACAACAGAATCCGCCCGAGTTGACGACAGCGaacttctcgttctcgtcccGGCCGCTGGTGGGCGAGTTCCTGCAACCGACGATGGGCCTCGTGGAGGCGGAATTCGTTAGATTGAGCGCTCAGGAAGTTGCGAGAAGATTGGAGGAACTGAGAACCGCCGCTGGTTTCAGGGACGTGCGGACGAACAATCAgtatgagagagagaagctagCGCACGCGAAAAAGCTGGCAAAGGAGGAGGCGCAGCGGAACAAGGTGCAGGCTAGGCTCATCAAGGAACAAGAGAAATCCGACAGGCAAGAGACGCTCAGGCGGGAGAAAGAGATTCGAAATCAACACCTGCTCGAGGGTCGAAAGCGGCTAGCGTTCACGATCAAGCAGAAAATGAAGATCATCCAAGAGATCGAACGCGGTAAGAGCAAGAGCGACGTGGCGCGCGAGCTGGGTCTGGCTAGCAGCACGGTGGCCACCATCTGGAAGAATCGAGAGAGCATCGCGGAAAGTTGGAGGAACCGCGACATGATGCATCACTCTGATGTCGAGGACTCGATCGTAAAAAAGTCCGGcctctcctcgtcgtcgtcgtcgtcgtcgtccaaTTTGGCCTCCGTCGCGTCCTTGGTGACCAACAATACGGTGTTGAACACCGTAAACACCATCAACAGCAGCACCGCCAACGTCACGTTGCCCGCTGCTGCCGTCGTGGTAACACCGCCACAGGTGCAGGTGGTGCCGCctccgccaccgccgccaccaccaccgccaccgccgccgccgccgccgccgccgccgccgcctctcCCATTGCCGACCACCTCCGCCGCGATCGTCCCGTCGACCTCGCAACCGACGCAGCTCTCCACACCGTCAACCTCCAGCACCGCGTCCACAggcaccaccaccaccatcaacGCCAGCATGGACAATACACAGCAGGCCCAGACCCAGACGCAAAGTCAGGAGCTTCTGGAGGCTCGGAAAAAACGGCAGGAAGAGGTGGAGAAGATGCGACTGGAAGAGCAACAACGGAAGCAACAGGAACGGGAGCTGAAGCGGCAGCAGGCGGTTATGCTGAAAGAACAGATATACATGCAGGAGCTCACCAAGCAGCGCGAGATGCTCTACACCGTCGAGCTGGAGAGAGAGCGGAGGAGACAGCACATGGCGTTGGTTCGAGCACTGgagaatcgtcgaaaaatggaggagaaggagaagaaacgacTGGAGGCGAGGGCCGAGAGAATAGCGACGAAGGAGAAACGCGCCGAACAGAGGAAGGTGGAGATGGAACTGATCGAACAGATCAGAAAGCCTGTGGAGGACATGGAGCTAACGGATCACAGATCACTGCCAGAATTGAAGCGAATACCCGGTCTCAAGCTGTCTGGCCAGGCATTCGCAGACATCGTGATGGTGTTCGAGTTTCTGCATAATTTTGGTGAAACCTTAGGCTTCGATATGGAGTCGCTGCCAAGCCTAAAGAGCCTTCAGCTGGCGCTACTGAACGACGAGGAAGCCGAGGAGGAACTCCTCTCGGTAATGACGCATCTGCTGGTATGCGCGATCGAGGATCCTGGGATCCCTCAACCAGCGAGACACACGACCGGCCTTGGTCAGAGTTTGCGTCAAGCTGACATAACGCACGCCAACATCAGCGAGGTTCTACGAATCTACTTGTACGCGAACGCGACAGGGGAGGTGAAGGCTTTGACAGGCGTGTGTCTGGAACGAGAACGCGACAAAAAGTTCGCGGATCATCATCAGAACGGTGGTGACTATGCCTCGACTTGCTCGGGCAAGAACGCCCAGTTCTACGAACATTTGCACAATAACGAGACCTGGAAGATGTCCGAGAGGTTGAGGGACAAACCATTCCTAGCCTTGAATCCAACGCACAAGGCGCAGATGCTCGCGTTCCTCTGCAACGAGCTGTTGCAGAACAAGGCTGTGATCAGACAGATCGAGGGTAGCTTGGAAACGGTGGCTCAATTGAGAAAAGAGAGATTCGTTTTGGACACGAAGATCAGAAAGCTGAGACAATTGCACAGTCGAAAAGTGCGAATGGAGGCGGTAGGCGTGATCGTCAATAAAACTGGAGACACTATCACcatcgagaagaaagaagtcgACGAGGAAGGCAACACGACGTCGACAGCAGTGGGAACAACGCCTACCCCCGACGAAATTCATCACGAAGACGAGGTTGAAGACATGTCCGAGAACGAGAGCGAAGGAACTCAACCCGAAGAGGAGGAGGACAAGAATCTGTCTGGCGAGGAGCTCGGCAAGAAATTGGATAAACTATTGAAACAGTCGGAAGAGCAATTGCAGAAATTGAACAGCTCCTCGAAGCAGCTACGAGCGCATATATTTGGGCAAGACAGGTACTGGCGAAGATACTGGGAACTGGCGTGCGCAGGCGGCATTTTCGTGGAGGCCATGGAAAGCGCCGAACCTGAGATCCTCGAGCTGCAGGCTGAACTAGACGAAAAGTACAAAAACGTGGCGGTGGAAGAGAAGTCGGAAACGAAACAGGAGGACACGAAAGTCGAGAATCGCGAGAACGAAGCCCCGAACGACgtgaagaaggagaagaaattcaattcgaacGAGCAAGAGGAGGACGCGAAACCTTTGGCGGATAAAACAAAGTCTGAAATCGAAGATGTTAATTGCAAGAAGGAACCGATGCAGAACTGCGAAAATTTGACGAACGtgaaggaggagaagaagaacgatTTGGACAATTCGGTGGCGGATGCGAAGACCAACGTCACGTCTGAGGAGATTAAACAGGAAACAGAAGTGGTCAATATGGATGTGGATGTGAaagaagagacgaagaaagagaacgacGAAACGGACGAAGACGTGAAACCAGCGGTGAAAATGATGGAAGataaaatcgtcgaaacgattcCAAATGGTGACAAGTTCAACCATGTTAATAACCTTCACAACGGAAAGGAATTAAACGGCACCTTTATTTCTAATAACAGCAACGAATCCAATTGGTTCTCAATTTTACCTCGGGAGACTTGCGATACTCCAGGACCAAGTACCAAGCAAATATTTGGTATAGCCGAACCAACCGAATTAAGAATACCAGTATTCCCTCCGCCGGCTAGTCCGAACTACGACAGATGTGACAGTCCGGCTCCTTTGATTTTGACTCAGGACGAGGCAGCGCAGCTTGAATACTTGAAAGTACATGGCTTGCCACCTCCCGGAGAAGCGAAACCAGTACCGAAAGACCTGAGATACGGTTGGTGGAGAATAACGGACGTCGACACGTTTCAAGAACTGTTGGAACACCTTCATTCCCGCGGCGTTCGCGAGAAGGAGCTAAAACGAACAACGTGGGCGACCATGGAATCCTTCCTAGCTGTTACCGGCAAGATCAACGTGGATCCGGGTAACCTTACCGCTACCGAACTTCAAGCGACGCCCGATGAACCCGACACACCGATTCCGAAACCGGACAACCCAGCAGACTGGAGCGAACAAGTCGCGTTACGTGTTGATGCGCAATTATTGGAACAAGTCGAGGCACTGGAAGACAAAGTTGCAAATGCCAGCATGCAGGTCAAAGGCTGGAAGTTACCTCCACGGGCAGGAACCGAAGAGGCcgaagaaattgagaaactgAACGAAATGGAGAAAATTAGCGCTGTTGAACAAGCTCGACAAAGGTTACTGTCTCTGGAAGCAGCTATCGAGAGGAGATATTTAAAACCACCGTTGGGTGTTTGTACGGGAGATCCCAATCTAGCGGCTTTGAAGGCGGAACAAGCGGCCGCTGCGAACGCAAATTCGAGTAATTCCGATCAGAGCAATCAGACCCCGGTACCTCAAGAAGAAACGACTCCAAGAGGGCTGAACAACTGGCGAGAAGCTACGGCACGAGCACATACATCCGCTCAGCTTGCTATGGCGCTTTATATGTTGGAGGCCAGCATCGCATGGGACAAGAGCATCATGAAGGCTGTGAGTCTAACACCAGCTAGAAACTCGGTCTGCGTCAAGCTACGAAACCGCTGCGTCTCACTCAAAGCTACCACTCAATACAATCAGCTATTGACTACTTCTCAAACCTCTAATTGTCAGTTTTGTCATAGCGGAGATAATGAAGACAAACTATTATTGTGTGATGGTTGTGACCGCGGCTATCATACTTATTGTTTCCGTCCAAAAATGGAAAACATTCCTGATGGTGACTGGTATTGTCACGAATGCATGAACAAAGCCACAGGAGAACGAAACTGTTTGGTATGTGGAAAGAGGGTTGGTAAAAATTTAGTGCTATGTGAACTCTGTCCACGGGCTTATCACACTGACTGCCACAATCCTGTTATGCCAAAAATGCCGAGGGGAAAATGGTACTGTTCTAATTGCCACAGTAAACAACCAAAGAAGAGAAATAGTAGTCGAAGGAGTCATACCAAAGGGGGAGGCACCAGAGAAAGTGAAAGTTCTGAACATCCACCAGCTAGTCCAACGCCGTCAACGGCATCGAACACACACGTAGAGGACGTCAGTTCATCGGAACCAGCAACCCCAACTGCCTCGCCACGGAAGGAGGGAAACAATAGGACGCTCACGAAGAAACAACAACGAGAGTTGGCTCCTTGTAAGGTGCTACTCGAACAGTTGGAGCAACAGGACGAGGCCTGGCCGTTCCTCTTGCCGGTGAACACCAAACAGTTTCCTACCtacaagaaaattattaaaacaccCATGGATCTCAGTACGATCAAGAAGAAATTGCAGGACTCCGTGTACAAGTCTCGCGATGAGTTTTGCGCCGATGTCAGACAGATGTTCATCAACTGCGAGGTATTCAACGAGGATGACAGCCCCGTGGGGAAGGCTGGACACGGAATGCGCAGTTTCTTTGAAATGCGTTGGACCGAGATTACTGGCGCACCACCTCCACACCCACAAACGCATAGCTGA
Protein Sequence
MPGGYGLGAHHLPSAYAILGRGGSAPGFGGHTPASAPPPPPYSHSSLGTLSVAASQAASLGINPASAAWWTMASHLAAQDYLARLQGAAGLPGFPPGAESLLPPYPASLLNPPSLSSHKSSKSKSSKSHKTPASSSSSSSSSTTPSMTSSSLPVSTQAPVTSSHHSTSASSTPNSQTNVVSDPSSILGGVRLPPDTEIIKYTSSIVGPKVPGTTNRGRKKTISLDTPSVSVHPPPVPALSAHQTNTTTSSLMMEPRKYNRTGTESNDYRESVDRVEVIKLPAHSTNGSVLPAPTSYTTTTNASNSNDSDAPLNLSLKPATTSSSSPISGSQPLSQLSNLSQSLLASDRTSRRKPGPKPRRVPQNSVPVPASPSTSLAQMFAAADSPQRPSSGSEESESASTTHHKDGRPRNLGRGVSKPKKNTVASLLAQSRALGIKPTPTLDPSVPLSHQVSLLRSNILAAQLHGTSTGQIDDKNQRSLQEKMKNKLLEVSGEESNMDVTSESGSNTDVVTDTDDDNADGVSSAKRRKMKPSERDLQVPLERGWKREIVIKGLGKSGVIKGDVSYYSPCGKTFRSSPDLAKFLEQQNPPELTTANFSFSSRPLVGEFLQPTMGLVEAEFVRLSAQEVARRLEELRTAAGFRDVRTNNQYEREKLAHAKKLAKEEAQRNKVQARLIKEQEKSDRQETLRREKEIRNQHLLEGRKRLAFTIKQKMKIIQEIERGKSKSDVARELGLASSTVATIWKNRESIAESWRNRDMMHHSDVEDSIVKKSGLSSSSSSSSSNLASVASLVTNNTVLNTVNTINSSTANVTLPAAAVVVTPPQVQVVPPPPPPPPPPPPPPPPPPPPPPLPLPTTSAAIVPSTSQPTQLSTPSTSSTASTGTTTTINASMDNTQQAQTQTQSQELLEARKKRQEEVEKMRLEEQQRKQQERELKRQQAVMLKEQIYMQELTKQREMLYTVELERERRRQHMALVRALENRRKMEEKEKKRLEARAERIATKEKRAEQRKVEMELIEQIRKPVEDMELTDHRSLPELKRIPGLKLSGQAFADIVMVFEFLHNFGETLGFDMESLPSLKSLQLALLNDEEAEEELLSVMTHLLVCAIEDPGIPQPARHTTGLGQSLRQADITHANISEVLRIYLYANATGEVKALTGVCLERERDKKFADHHQNGGDYASTCSGKNAQFYEHLHNNETWKMSERLRDKPFLALNPTHKAQMLAFLCNELLQNKAVIRQIEGSLETVAQLRKERFVLDTKIRKLRQLHSRKVRMEAVGVIVNKTGDTITIEKKEVDEEGNTTSTAVGTTPTPDEIHHEDEVEDMSENESEGTQPEEEEDKNLSGEELGKKLDKLLKQSEEQLQKLNSSSKQLRAHIFGQDRYWRRYWELACAGGIFVEAMESAEPEILELQAELDEKYKNVAVEEKSETKQEDTKVENRENEAPNDVKKEKKFNSNEQEEDAKPLADKTKSEIEDVNCKKEPMQNCENLTNVKEEKKNDLDNSVADAKTNVTSEEIKQETEVVNMDVDVKEETKKENDETDEDVKPAVKMMEDKIVETIPNGDKFNHVNNLHNGKELNGTFISNNSNESNWFSILPRETCDTPGPSTKQIFGIAEPTELRIPVFPPPASPNYDRCDSPAPLILTQDEAAQLEYLKVHGLPPPGEAKPVPKDLRYGWWRITDVDTFQELLEHLHSRGVREKELKRTTWATMESFLAVTGKINVDPGNLTATELQATPDEPDTPIPKPDNPADWSEQVALRVDAQLLEQVEALEDKVANASMQVKGWKLPPRAGTEEAEEIEKLNEMEKISAVEQARQRLLSLEAAIERRYLKPPLGVCTGDPNLAALKAEQAAAANANSSNSDQSNQTPVPQEETTPRGLNNWREATARAHTSAQLAMALYMLEASIAWDKSIMKAVSLTPARNSVCVKLRNRCVSLKATTQYNQLLTTSQTSNCQFCHSGDNEDKLLLCDGCDRGYHTYCFRPKMENIPDGDWYCHECMNKATGERNCLVCGKRVGKNLVLCELCPRAYHTDCHNPVMPKMPRGKWYCSNCHSKQPKKRNSSRRSHTKGGGTRESESSEHPPASPTPSTASNTHVEDVSSSEPATPTASPRKEGNNRTLTKKQQRELAPCKVLLEQLEQQDEAWPFLLPVNTKQFPTYKKIIKTPMDLSTIKKKLQDSVYKSRDEFCADVRQMFINCEVFNEDDSPVGKAGHGMRSFFEMRWTEITGAPPPHPQTHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00684165;
90% Identity
iTF_01539601;
80% Identity
-