Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.014 1.6e+02 4.2 0.3 26 49 112 135 105 143 0.86

2 7 0.13 1.5e+03 1.0 0.0 27 48 142 163 137 167 0.83

3 7 0.00053 6.2 8.7 0.0 14 44 213 244 205 248 0.78

4 7 0.02 2.4e+02 3.6 0.0 22 48 249 274 245 278 0.84

5 7 0.018 2.2e+02 3.7 0.0 21 43 276 298 273 305 0.88

6 7 0.00098 11 7.8 0.1 23 46 306 328 299 332 0.85

7 7 0.006 71 5.3 0.0 21 45 332 356 328 358 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.014	1.6e+02	4.2	0.3	26	49	112	135	105	143	0.86
2	7	0.13	1.5e+03	1.0	0.0	27	48	142	163	137	167	0.83
3	7	0.00053	6.2	8.7	0.0	14	44	213	244	205	248	0.78
4	7	0.02	2.4e+02	3.6	0.0	22	48	249	274	245	278	0.84
5	7	0.018	2.2e+02	3.7	0.0	21	43	276	298	273	305	0.88
6	7	0.00098	11	7.8	0.1	23	46	306	328	299	332	0.85
7	7	0.006	71	5.3	0.0	21	45	332	356	328	358	0.90

Coding Sequence: ATGGATCTAAACATTCCAAATCGAGAAATAAAAACTGAACCAATTGATTCTATTGAAGAGGTGAatattaaatatgaaaattgcACTGAACCCGATGTTCGGAACTCTGTTTGTGACAAACAGATTGAAACCGAGCTGAAAATAGAGTTTGTTAACATAAAAACTGAACCAAATGGTGTCGTGGAACAAGTTAAACAGGAATATTTTGATGTGGAAACTGAACCAACTATAGCTTTCGaggaaacaatcgtaaaatcggAACATTTACAAAATTCCGATAACCACAACATTGACGAACCCCAAATACAGTATATGCGTACCCATTCGGGATTCGAATGCAGCGTTTGCGACTACTCGTGCAAGACCTCATTTAATATTAAACGTCACGTAAAACGGTTACACATGGGACAAAAACACTTTAAATGCGGAACCTGCAATTTCACTGCAGTCCAATCTTACGACCTTAAAATACACCTACAAATTCACGCACTGGTCAAGTTGTACAAGTGTACTACGTGCGAATACGCTGGTAGTACAACGTGGAAGCTCAAACGTCACATGGCAATACACACAGGTGACGGAAAAACTCACAAATGCCCAACGTGTGACTTTACTTCTCCAGATACTGGTAACCTCAAAGTTCATATGAGATCTCATACAGGCGAAAAGCCTTACAAATGCACGATTTGCGTGTACGCTGGGACAACATCGTCGAAACTCAAACGTCACATGACTACGCATGGTGAAAAGATGGATGCATGCGGTATGTGTGATTTTGCTACAAACCAAGCGTATGAACTCAAAAGACATATGTTAAAGCATACCACTGAGAAGTCGTACACTTGTGATGAGTGTGATTATGTTACTGCTAAGATGAGTGATCTCCGAAGGCATAAGAGAAAACATACTGGTGTGAGGCCGCATAGCTGTGCAgtctgtgattatgctagtacacAATCATCAGATCTCAAAAGACATATGTTGAAACATACAAAGGAGAAGCCTTATACGTGCAAGTCTTGCGATTTTGCAGCGTCAACATCGTATAATCTTAAAACGCATATGCAAACACATAATTAA
Protein Sequence: MDLNIPNREIKTEPIDSIEEVNIKYENCTEPDVRNSVCDKQIETELKIEFVNIKTEPNGVVEQVKQEYFDVETEPTIAFEETIVKSEHLQNSDNHNIDEPQIQYMRTHSGFECSVCDYSCKTSFNIKRHVKRLHMGQKHFKCGTCNFTAVQSYDLKIHLQIHALVKLYKCTTCEYAGSTTWKLKRHMAIHTGDGKTHKCPTCDFTSPDTGNLKVHMRSHTGEKPYKCTICVYAGTTSSKLKRHMTTHGEKMDACGMCDFATNQAYELKRHMLKHTTEKSYTCDECDYVTAKMSDLRRHKRKHTGVRPHSCAVCDYASTQSSDLKRHMLKHTKEKPYTCKSCDFAASTSYNLKTHMQTHN

Sequence clustering based on sequence similarity using MMseqs2