Basic Information

Insect: Melangyna quadrimaculata
Gene Symbol: wdn
Assembly: GCA_949320155.1
Location: OX439483.1:468053709-468059686[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.13 34 7.2 0.6 1 23 239 261 239 261 0.96

2 8 3.7e-06 0.00097 21.5 0.4 2 23 266 287 265 287 0.97

3 8 0.05 13 8.5 1.8 2 23 298 318 297 318 0.93

4 8 2.3e-06 0.00059 22.2 1.0 3 23 326 346 324 346 0.98

5 8 9e-06 0.0023 20.3 3.0 1 23 352 374 352 374 0.98

6 8 0.00026 0.069 15.7 3.2 1 23 380 402 380 402 0.96

7 8 1.1e-05 0.0027 20.1 1.1 1 23 408 430 408 430 0.96

8 8 0.00033 0.085 15.4 3.3 1 23 436 459 436 459 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.13	34	7.2	0.6	1	23	239	261	239	261	0.96
2	8	3.7e-06	0.00097	21.5	0.4	2	23	266	287	265	287	0.97
3	8	0.05	13	8.5	1.8	2	23	298	318	297	318	0.93
4	8	2.3e-06	0.00059	22.2	1.0	3	23	326	346	324	346	0.98
5	8	9e-06	0.0023	20.3	3.0	1	23	352	374	352	374	0.98
6	8	0.00026	0.069	15.7	3.2	1	23	380	402	380	402	0.96
7	8	1.1e-05	0.0027	20.1	1.1	1	23	408	430	408	430	0.96
8	8	0.00033	0.085	15.4	3.3	1	23	436	459	436	459	0.98

Sequence Information

Coding Sequence: atgaaggAAAAGGGCCTCCTAAGTAAATCCACGCCCACGTCCAACAACGATGAGATATTAACGTCGCTGTTGAAGATCAATAATTTCGATAACAGCATCAAGGATGAGTCCCTGGACATCGATTTGTCGGCATGTGTAACTATATCCCCCGATCCGACCATCCTAAGTAAATCCACTCCCACGTCCAACAACGATGAGATATTAACGTCGCTCTTGAAGATCAATAATTTCGATAACAGCATCAAGGATGAGTCCCTGGACATAAATCTGTCGGCATGTGTAACTATATCCGCCGATCCGACCATCATCTGCAACAATAGTCTATCGTCAGACTTCTGGAAGGTCTTCGACGAAAGTGCCCAAGCCGATGAAAGCAGCAGTGCCATTACTAACCGATCTACAGCGGTGGAGAGCATTAATTTCGTAAGCCTACTTCCTCCACCGCCACCTGCAGAAGTTCACAAGGTCTTGACTGGATGGGGGAGTGCTGTGCCTTCTCCGATCTTACCCTCTCCcacaaagaaaaaacacaaaaatcgaaaacaaactaagcaaacaaaaattattcccGACGAGAAGAATGCACAACGACGAGCGCCGGATGCTCCAGCGACTACAATAAACCAACTTCCGATCTCAAATAGTTTTAAGGGTAATTTTCCGATTGCTGTAAATAAGCCGGATGCTGAAACACCACAACGACAAGCCTACAAATTCAAATGCGAACACTGTCGAGTTGTGTTGGACGGGCTGGAGGATTTCACCAAGCACGAAGCTTCTCACAAGATTCTAATCAAATGCAATGAATGTGATCGTGAATTTGCCAACGAGAGTGGCTTAAAGAAACACGTTAAGAGTCATCGGGATGACACTAGGAAGGATGGCTGGAAGAAGTGCCCCGACTGTGGCAAATGTTTGAAACTGGGAAGCATGTGGATGCACAGGAAAATCCATAGTGATAATAAAAAATACGGCTGTGATATATGTggccaaaaatttgttcaaaaaattaatcttaCCCATCATCAAAGAGTACACACAGCAGAAAAACCCTACGAATGTGCTGAATGTCCAAAAAGaTTTCAAGAACGATCTCATTTGCAACGCCATCAAAAGTACCATGCCCAAACCCGTCCTTTTCGATGTGAAAAATGTGGTAAAATGTACAAAACCGAACGTTGCCTCAAAGTACATAACCTTGTTCATCTGGAACAGCGTCCTTTTGCATGCCAAGTATGCAACAAAAGCTTCATAAGTAACTCTAAATTAAAGCAACACTCAAATATTCACACTGGTGAACGTCCGTTCAAATGCAACTACTGTACAagagattttacaaatttcCCCAATTGGTTGAAGCACACACGCAGACGTCACAAAGTAGATCATAAAACTGGAGAACTTCTAGAGCACATGCCTTCGTATTGTACAAAATCAGGAAAGAAATCTGCGGCAGCAGCTGGAGGTGATGCCGGGGCAAAATcaacgaagaagaagaagaaagtcGAGACGGAGCAGAATAAAGTAGTATTGATCACATCACAGCCGCAACCGCCACCATCGCTACCGCTACCAAAGTCTTGCCAATCACCTCCCTCCGTCCAGcttatgaaagccaaaattaaaCTGGAACCAGGCCAGGAAGCTGCGGAAGTTCGCAACAATACTAATTTCACGGATTTACACTCTCTAAGCATAACCAGTGCCGAGGAACTAATTATGGAACAAGCCCTCGAAATGGaagaattttgtttctataaatcGCAATTGGACCAGTTTTGTATGCAAAAAGAATTTTCTGTAAAGAAAGAATTCGAAAATAAAGCTTTGTGCTCAGTAGACTCTTCGCCGTTTTCTTCGCCAGCTTCTGTCGAACTTCCCATCACATACAACATTCAGTCTCTTCCGTCTACTACAGTATCGACAGCAGGAAGAACTACATCATCCGAATCTGCACCATCCAATAAAATGCGCATACAAGTCTTCAAGAATCAAACACTTCCGTCCGTCGATACTTTAATAAATGCTTGCTTCTTTAAAAGTGAAaatcaaaatatgtaa
Protein Sequence: MKEKGLLSKSTPTSNNDEILTSLLKINNFDNSIKDESLDIDLSACVTISPDPTILSKSTPTSNNDEILTSLLKINNFDNSIKDESLDINLSACVTISADPTIICNNSLSSDFWKVFDESAQADESSSAITNRSTAVESINFVSLLPPPPPAEVHKVLTGWGSAVPSPILPSPTKKKHKNRKQTKQTKIIPDEKNAQRRAPDAPATTINQLPISNSFKGNFPIAVNKPDAETPQRQAYKFKCEHCRVVLDGLEDFTKHEASHKILIKCNECDREFANESGLKKHVKSHRDDTRKDGWKKCPDCGKCLKLGSMWMHRKIHSDNKKYGCDICGQKFVQKINLTHHQRVHTAEKPYECAECPKRFQERSHLQRHQKYHAQTRPFRCEKCGKMYKTERCLKVHNLVHLEQRPFACQVCNKSFISNSKLKQHSNIHTGERPFKCNYCTRDFTNFPNWLKHTRRRHKVDHKTGELLEHMPSYCTKSGKKSAAAAGGDAGAKSTKKKKKVETEQNKVVLITSQPQPPPSLPLPKSCQSPPSVQLMKAKIKLEPGQEAAEVRNNTNFTDLHSLSITSAEELIMEQALEMEEFCFYKSQLDQFCMQKEFSVKKEFENKALCSVDSSPFSSPASVELPITYNIQSLPSTTVSTAGRTTSSESAPSNKMRIQVFKNQTLPSVDTLINACFFKSENQNM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00426595; iTF_01212259; iTF_00694934; iTF_01396825; iTF_00694078; iTF_01318496; iTF_00664333; iTF_00894241; iTF_00335342; iTF_00984494; iTF_00188463; iTF_00665967; iTF_00665113; iTF_00427550;
90% Identity: -
80% Identity: -