Murs012300.1
Basic Information
- Insect
- Megathymus ursus
- Gene Symbol
- LZTR1
- Assembly
- GCA_003671415.1
- Location
- PDGT01000008.1:4579054-4591259[+]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 9.1e-16 3.3e-13 50.1 0.0 4 106 355 487 352 491 0.88 2 4 0.5 1.8e+02 2.7 0.0 80 108 493 521 487 523 0.88 3 4 3e-17 1.1e-14 54.9 0.0 9 97 591 679 588 694 0.86 4 4 1.7 6.1e+02 1.0 0.0 77 106 693 722 682 725 0.79
Sequence Information
- Coding Sequence
- ATGCAGAACCGGGAGATGTTGATCAATGATCAGCTTCGCAATCCCAATGAGCTTGACATTAGCCTCAGAATGGAGTTTGGACCATTTGAAACAGTGCACAAATGGAAACGCATACGCAGCAAGCACACAGCGGTAGCCTACAAGGATGCAATCTATGTGTTTGGCGGTGACAATGGCAAATCCATGTTGAATGATCTGATAAGATTTGACATTAGAGAAAAGTCATGGACGAAGATGGGATGCATGGGCACTCCACCAGCACCTAGATATCATCATTCTGCAGTGGTGCACAGGTCATCCATGTTCGTATTTGGAGGCTACACTGGAGACATCCTCGCCAACTCTAACCTGACCAATAAGAATGATCTATTTGAGTACAAGTTTCAAAGTGCGCAATGGGTGCAGTGGAAATTCTCTGGACAGGAACCGGTGCCCCGCTCGGCGCACGGCGCAGCAGTATATGACGACAAGCTTTGGATATTCGCGGGATATGACGGCAACGCGCGGCTCAACGACATGTGGACTATCAACTTAGTGCAGGGGGAGGAGCATCAGTGGAAATGTGTGGAGCAGAAGGGCGAGTGTCCACCGACGTGCTGCAACTTCCCGGTCGCTGTGGCCAGGGGCAAGATGTACGTGTTCAGCGGACAGAGCGGCGCTAAGATCACCAATGCGCTGTTCCAATTCGATTTTGAAACTCACACGTGGAGCAGGGTGTGCACTGAGCACCTGCTGCGCAGCGCGGGCCCGGCGCCGGCGCGGCGCTACGGGCACGTGATGGTGCCACATGGACGACACTTGTACGTGTTCGGCGGAGCCGCCGACAGCACGCTGCCTTCTGACCTGCACTGCTTCGACTTGGACACGCAGATGTGGTCGGTGATCCTCCCAGCGGCGGACTCGCAAATTCCGCTGGGGCGGCTGTTCCACGCGGGCGCGGTCGTAGGCGACGCCATGTACATATTTGGCGGTACCGTCGACAACAATGTCCGCAGTGGCGACCTCTACAGGTTCCAGCTATCAAACTATCCGCGTTGTACCTTGCACGACGACTTTGGGCGAATCCTGAAGTCGCAACAGTTCTGTGACGTCACCATCCTGGTGGGCCCCGAGGAGACCACGGTCATCGCGCACCAGGCCATGCTCGCGGCCAGGTCACAGTATCTGCGACTGAAAATTAACAAAGCACGAGTGGAGCTCGCCCGTAAGATAGCCGACAGGGAGGTGGAGCCGGTGACGTGGTCGTACAAGGCGCAGCCGCAGCTCTCCATCCGCCTGCCCGAGGCCACTCCGGAGGCCTTCCACATGATACTCAACTACATATACACGGACCGGATTGATCCCACCGAGAAAGATGACGACCCTGGCTCTCCAGCGACAATACTCCTGGTGATGGAGGTGTTGCGGCTGGCGCTCACCTTGAAAATCCCTCGACTGAAGGGGCTCTGCGCGCGGTACCTAGGCCTTAATCTAGGCCTCGGGAATGTTCTCCAGGCACTTCACGCCGCACACTACGCCGGCTTGCACTGCATCAAAGAACATTGTATTAAGTTCGTGATAAAGGAGTACAACTTCACTCAGATCGTGATGTCAAAGGCGTTCGAGGTGCTCGAGCAGAAACTGATGGTTGAGGTAATCCGCCGCCACCAGTCACCGCCGCAAAAGACCTCCACGCATAACAACCTTGAAAACGATGAGGAAATCGTGGGCACGACGTTGGAGCAGGACATGTGTATGTTCATGTCGGCGGGCGTTGGCGGTGGCGGCGCAGAGCTGGCGGACGTACAGCTGCGTGTGGGCGGCGCCGTGCGGCCCGCGCACCGCTCCGTGCTCGCCGCGCGCGCTTCATACTTCGAGGCCATGTTCCGCTCTTTTTCGCCGCAGGACAATATCGTCAACATACAAATTTGCGACACGGTGCCATCCGAGGAAGCGTTCGATTCCCTGCTGCGATACATCTACTACGGAGATACCAACATGCCAACTGAAGATTCTCTTTATTTATTCCAGGCACCGATATATTacgGGTTTACCAACAACCGGCTTCAAGTATTCTGCAAGCACAACTTGCAGAGCAATGTGTCGCCCGACAACGTGTTGGCAATCCTGCAGGCGGCTGACCGCATGCGCACGGCCGATATCAAAGAGTATGCGCTCAAGATGATCGTACATCACTTCCCGCTGGTGGCCCGGCAAGATGCAATCAAGAATCTAGCCCAACCTTTACTTGTAGACATTGTGACAGCCCTCGCCGAAGAAAACCAGTGTGACACACCCCTGCCTCCGGCGCAACCTCGGTCGCTACCATCTTCCTCCTCAGCTGATACACTCTCAGATGACCCAGAGTATATTCGTCTGCACAGATCGTTTAAGTCCTAG
- Protein Sequence
- MQNREMLINDQLRNPNELDISLRMEFGPFETVHKWKRIRSKHTAVAYKDAIYVFGGDNGKSMLNDLIRFDIREKSWTKMGCMGTPPAPRYHHSAVVHRSSMFVFGGYTGDILANSNLTNKNDLFEYKFQSAQWVQWKFSGQEPVPRSAHGAAVYDDKLWIFAGYDGNARLNDMWTINLVQGEEHQWKCVEQKGECPPTCCNFPVAVARGKMYVFSGQSGAKITNALFQFDFETHTWSRVCTEHLLRSAGPAPARRYGHVMVPHGRHLYVFGGAADSTLPSDLHCFDLDTQMWSVILPAADSQIPLGRLFHAGAVVGDAMYIFGGTVDNNVRSGDLYRFQLSNYPRCTLHDDFGRILKSQQFCDVTILVGPEETTVIAHQAMLAARSQYLRLKINKARVELARKIADREVEPVTWSYKAQPQLSIRLPEATPEAFHMILNYIYTDRIDPTEKDDDPGSPATILLVMEVLRLALTLKIPRLKGLCARYLGLNLGLGNVLQALHAAHYAGLHCIKEHCIKFVIKEYNFTQIVMSKAFEVLEQKLMVEVIRRHQSPPQKTSTHNNLENDEEIVGTTLEQDMCMFMSAGVGGGGAELADVQLRVGGAVRPAHRSVLAARASYFEAMFRSFSPQDNIVNIQICDTVPSEEAFDSLLRYIYYGDTNMPTEDSLYLFQAPIYYGFTNNRLQVFCKHNLQSNVSPDNVLAILQAADRMRTADIKEYALKMIVHHFPLVARQDAIKNLAQPLLVDIVTALAEENQCDTPLPPAQPRSLPSSSSADTLSDDPEYIRLHRSFKS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00887497;
- 90% Identity
- iTF_00673595;
- 80% Identity
- -