Lacc011848.1
Basic Information
- Insect
- Lerema accius
- Gene Symbol
- Lztr1
- Assembly
- None
- Location
- scaffold949:1183909-1194300[+]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 4.5e-15 1.3e-12 47.8 0.0 4 106 372 504 369 508 0.85 2 4 0.69 2e+02 2.1 0.0 79 108 509 538 503 540 0.87 3 4 5.6e-18 1.6e-15 57.1 0.0 9 97 606 694 603 709 0.87 4 4 1.6 4.7e+02 0.9 0.0 77 106 708 737 697 740 0.79
Sequence Information
- Coding Sequence
- ATGACCAGAAAATCAGCATTAATGCAGAACCGGGAGATGTTGATCAATGATCAGCTGCGCAATCCCAATGAGCTAGATATCAGCCTCAGGATGGAGTTTGGTCCGTTTGAAACTGTGCACAAATGGAAACGCATGTCGGAATGCTATGAATTTGTTGGTGCAAGACGCAGCAAGCATACTGCTGTGGCTTATAAGGATGCAATTTATGTGTTTGGTGGGGATAATGGCAAATCCATGTTGAATGATCTAATAAGATTTGACATTAGAGAAAAATCATGGACAAAAATGGGGTGCATGGGCCCTCCTCCAGCGCCGAGATATCATCATTCTGCAGTGGTGCATAGATCATCAATGTTTGTATTCGGTGGGTATACAGGGGACATACTGGCTAACTCCAACCTAACCAATAAGAATGATCTGTTTGAATACAAGTTTCAAAGTGCACAGTGGGTGCAATGGAGGTTCACTGGACAGGAACCAGTGCCACGGTCGGCGCACGGTGCGGCTGTCTATGACGACAAGCTGTGGATATTCGCAGGGTATGACGGCAACGCTCGGCTCAATGACATGTGGACTATCAATCTAGTGCAGGGCGAGGAGCACCAGTGGGAGTGCGTGGAGCAGAAGGGCGAGTGTCCGCCGACGTGCTGCAACTTCCCGGTGGCGGTGGCGCGCGGCAAGATGTTCGTGTTCAGCGGACAGAGCGGCGCTAAGATCACCAATGCACTGTTCCAGTTCGATTTTGAAACACACACGTGGAGCCGCGTGTGCACAGAGCACCTGCTACGCAGCGCGGGCCCGGCGCCGGCGCGGCGCTACGGCCACGTGATGGTGCCGCACGGACGACACCTGTACGTGTTCGGCGGCGCCGCCGACAGCACGCTGCCCTCCGATCTGCACTGCTTCGACCTCGATACGCAGATGTGGTCGGTGATCCTCCCGGCGCCGGAGTCGCAGATCCCGCTGGGGCGACTGTTCCATGCTGGCGCGGTGGTCGGCGATGCCATGTACATCTTCGGCGGTACTGTCGATAACAATGTTCGCAGCGGAGACCTGTACAGGTTCCAGCTGTCAAACTATCCCCGCTGCACCCTGCACGACGACTTCGGTCGTATCCTGAAGTCGCAGCAGTTCTGTGACGTCACGATCCTGGTGGGCCCCGAGGAGGTCACGGTACTGGCGCACCAGGCCATGCTCGCCGCTCGCTCGCAGTACCTCCGGCTTAAGATCAAAAAAGCGCGAGTGGAGCTGGCCAGCAAGATAGCAGCGGGTGAGGTGCAGCAGGTCTCGTGGTCGTACAAGGCGCAGCCGCAGCTCGTCGTCCGCCTGCCGGAGGCCACGCCCGAGGCCTTCCACATAATACTCAACTATATATACACCGACCGCATCGATCCTACTGAGAAGGATGATGACCCGGGTTCACCAGCGACGATCCTGCTGGTGATGGAGGTGTTGCGGCTGGCTCTGACGCTGAAGATCCCGCGGCTGAAGGGGCTGTGCGCGCACTACCTCGGCCTCAACCTCGGGCTCGGGAACGTGCTGCAGGCGCTGCACGCCGCGCACTACGCTGGCTTGCACTGCATCAAGGAACATTGTATTAGGTTCGTGATAAAGGAGTACAACTTCACTCAGATAGTGATGTCGAAGGCGTTCGAGGTGTTAGAACAGAAGCTGATGGTGGAGGTGATCCGCCGCCACCAGTCGCCGCCGCTGAAGGCCTCCGCGCAGAACAATCTGGAGAACGATGAGGAAATTGTTGGTACAACGCTAGAGCAGGACATGTGCGTGTTGATGGCGGCAGGCGGCGGCGGCGCCGAGCTGGCCGACGTGCAGCTGCGAGTGGGCAGCGCCACGCGGCCCGCGCACCGCTCCGTGCTCGCCGCGCGCGCATCGTACTTCGAGGCCATGTTCCGATCCTTCTCGCCGCAGGATAACATCGTCAATATACAAATCTGTGACATAGTGCCATCAGAAGAAGCGTTTGATTCCCTGCTGAGATACATCTACTATGGAGACACTAACATGCCCACGGAAGATTCGCTTTATTTATTCCAAGCACCTATATATTACGGGTTTACAAACAATCGACTGCAGGTGTTCTGCAAGCATAATCTGCAGAGCAACGTGTCCCCGGACAACGTGCTGGCTATCTTGCAGGCGGCCGACCGCATGCGCACTGCTGACATCAAGGAGTACGCCCTCAAGATGATCGTGCATCACTTTCCATTGGTTGCCCGGCAAGACGCGATTAAGAATCTGGCACAACCCTTACTTGTAGACATAGTGACAGCACTCGCTGAGGAGAATCAATGTGATACGCCGCTCCCTCCAGCGCAACCTCGGTCACTGCCGTCTTCATCCTCAGCAGATACACTCTCTGATGACCCAGAGTACATACGTCTGCACAGGTCGTTCAAGTCCTAG
- Protein Sequence
- MTRKSALMQNREMLINDQLRNPNELDISLRMEFGPFETVHKWKRMSECYEFVGARRSKHTAVAYKDAIYVFGGDNGKSMLNDLIRFDIREKSWTKMGCMGPPPAPRYHHSAVVHRSSMFVFGGYTGDILANSNLTNKNDLFEYKFQSAQWVQWRFTGQEPVPRSAHGAAVYDDKLWIFAGYDGNARLNDMWTINLVQGEEHQWECVEQKGECPPTCCNFPVAVARGKMFVFSGQSGAKITNALFQFDFETHTWSRVCTEHLLRSAGPAPARRYGHVMVPHGRHLYVFGGAADSTLPSDLHCFDLDTQMWSVILPAPESQIPLGRLFHAGAVVGDAMYIFGGTVDNNVRSGDLYRFQLSNYPRCTLHDDFGRILKSQQFCDVTILVGPEEVTVLAHQAMLAARSQYLRLKIKKARVELASKIAAGEVQQVSWSYKAQPQLVVRLPEATPEAFHIILNYIYTDRIDPTEKDDDPGSPATILLVMEVLRLALTLKIPRLKGLCAHYLGLNLGLGNVLQALHAAHYAGLHCIKEHCIRFVIKEYNFTQIVMSKAFEVLEQKLMVEVIRRHQSPPLKASAQNNLENDEEIVGTTLEQDMCVLMAAGGGGAELADVQLRVGSATRPAHRSVLAARASYFEAMFRSFSPQDNIVNIQICDIVPSEEAFDSLLRYIYYGDTNMPTEDSLYLFQAPIYYGFTNNRLQVFCKHNLQSNVSPDNVLAILQAADRMRTADIKEYALKMIVHHFPLVARQDAIKNLAQPLLVDIVTALAEENQCDTPLPPAQPRSLPSSSSADTLSDDPEYIRLHRSFKS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01439138; iTF_01082571; iTF_00673595; iTF_00795808; iTF_01361764; iTF_00970507; iTF_00971467; iTF_00288149;
- 90% Identity
- iTF_00673595;
- 80% Identity
- -