Mgen004351.1
Basic Information
- Insect
- Megalopta genalis
- Gene Symbol
- -
- Assembly
- GCA_011865705.1
- Location
- NW:489502-496759[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 22 7.6 4.1e+02 0.9 0.1 3 17 60 74 59 75 0.91 2 22 0.93 50 3.8 6.0 2 23 243 265 242 265 0.96 3 22 0.21 11 5.8 2.2 1 23 313 335 313 335 0.97 4 22 7 3.7e+02 1.0 2.7 1 23 384 406 384 406 0.94 5 22 0.044 2.4 7.9 0.2 1 19 462 480 462 482 0.93 6 22 7.8 4.2e+02 0.9 4.5 1 23 495 518 495 518 0.81 7 22 0.00045 0.024 14.2 0.4 1 23 523 545 523 545 0.93 8 22 0.00056 0.03 13.9 0.1 1 23 593 615 593 615 0.97 9 22 0.00054 0.029 14.0 0.1 1 23 621 643 621 643 0.97 10 22 2.1e-06 0.00011 21.5 0.3 2 23 687 709 687 709 0.96 11 22 0.13 7.1 6.4 1.1 3 23 718 739 716 739 0.82 12 22 1.4e-05 0.00073 19.0 0.3 2 23 747 769 747 769 0.97 13 22 9.7e-05 0.0052 16.3 0.1 1 23 777 799 777 799 0.94 14 22 0.025 1.3 8.7 0.4 1 20 859 878 859 878 0.97 15 22 0.01 0.54 9.9 0.1 1 23 896 918 896 918 0.96 16 22 3e-05 0.0016 17.9 0.9 1 23 936 958 936 958 0.97 17 22 0.0003 0.016 14.7 6.9 1 23 980 1003 980 1003 0.94 18 22 0.0062 0.33 10.6 1.3 2 23 1060 1082 1059 1082 0.95 19 22 1.7 93 2.9 2.4 3 23 1118 1139 1116 1139 0.88 20 22 0.011 0.59 9.8 0.3 1 23 1146 1170 1146 1170 0.93 21 22 0.03 1.6 8.5 1.7 1 23 1175 1198 1175 1198 0.97 22 22 0.036 1.9 8.2 2.3 2 23 1228 1250 1228 1250 0.94
Sequence Information
- Coding Sequence
- ATGGACAAGGTGGTGGTGTTGCAAAGAATGGAAAATGTGTGCAGGCTTTGCCTCTCCGAAGACGAGCCGAAATTGTCGGTGTTCGGGTCGCAAGAAACTCCGGTATCACTGGCCACTAAGATACAAGCCTGCCTATCGATTCAGATTTTAGCCACGGATAGGTTGTCGACGCAGATATGTTCACAGTGTGTTAAAAATGTGAATCAGTGGCATAATTATAAGGAAACATGCCTTCGGTCGCAAGATAAGTTACATCAATGGTTGGAAAAACATACACAATCTAGCCCAttgGTTGTGACTATCAAAGATGAACCCGTAGATCTGGACTTTTATGAAGACAATATTGAGGTCATTTCAGAATCTTCCATCGCATCAGAACTAGAATCTACTAACCTTGATGAAAGTCTAGATGACTCTGTAAACACGCTTCATATCCAAGAGATAAGTGATGATGAAACAGATGATGCAAGAGTTCCGCCAGCGTTAACAAAACCTTTCGATTCATGTATAAAGTCAGAGCCACCAGAGGATTGTGATACAGATTGTACTATAGAGATAGAGTCCATTACTGGCAGCGAGCTGGTGTTAAACCCCCTCTCGAACAAGGAAGATAGAATCATGGAAGCTGATTCTACGCAAAAGTCCAACGCGTCAGCATCAGTGATTAAAAAGAAACTTAGAAGAGGTCCTCATACTCATTATAGGGGACCACGTGCATTTAAGCAAAAGTGTGTGCATTGCCAAATCTTTTTGCATTCTAAATATACCTATACAAAGCACATGGAACGATTTCATTCGGATAAGCAAAATGGTAACGCTGATGACCAGGTGAAAGTTGAAGAAGAAGTTGAAGATCTGGAAGATGAATTAATGAGTATGGAGAAGGACGCGCCACTGACACAGGTGCAACAGAATATAATTAGTCAACTGAAGACTTTTTCATGTTATTCCTGTCAGCAGTTGTTCAGTGATCGCAGATCTACACTTTCACATATTCGTCAACACATGCCGGATCTGAGACCGTACACGTGTATCGCATGTTTAACAGAGTTCCCTGATCGCTCGATGTATAAGCTGCATTGCGGTGCGTCTTTCGAGTGCGCAATGAAAATCGCTCTAGTGATACCAAACCAAGGcgaggaaaaatatttcacatgcAACATGTGCTTGCGTTCCATGCCAAACAGAAAGGAATTGCTCTGCCATCTTTCAAAGCACTCTGATAAACAGTATCAACAATTAGTTAAGCCATCACGATCGCCTCCTAAACTCAAGCCAATTTCTCCTCTGCCAGCTGCTAAACAAGAGTCTCCTACAAAGAAATCAATCGCAGGCGGTCCGGATGTCCCTCATCCTTACAAAAACGGTGACCCAGCGCATAACCATATTTGCGATTTATGTGGCATGATCTACAGATACAAGCCTAACATGTTGAAGCATAAAGACTTGTGTCAGCGTTTGCAGCCAGATCTTCGAATCTCCTACAAGTGTATGCACTGCGGAATGACTTATCTGGTATTCAAGAAATTCCATAACCATATCACCCAAGACCATAAAAAGAAAGACTTTTTCTGTTCCGAATGTGGCGCTAAATTTAGATCACCTAGCGAATTCTTGATGCACTACGACGGGCATCGTGGTAAAATGAACAAGAAGCCAGTGTTGGAGAAGAACGACTCAGCTGCCAAAAATGCGCAGAACTTCTCAATGCCCATCAAAGATTGGGACACGTTTGAGGCTGAAATGAATGACGGCAGGTTATCCGACAGTAACCAGTACAGTTGTGCTTTGTGCAATTTGGAATTTGCTACTAGAGCCGAGTTGACGGAGCACAGGAACCTTCATCTGAAAGTGAAGATCTATTCTTGCGTGATTTGCCGCAGTATGTTCAGCAGCGCGGGTGCTTTGGAGATCCACATGAAGGATCATGGTATAGAGGACCCCGGCGAGAGAAACGCGAACAGCTCGTGCGTAGAGTACGGAACCATGAAGGACAGTCCAGAGGATTGTAAACCGTTGAACGTGAGCGCCACCTCAGACCCAGGCCCTAAAAAGAACGAGTGCCGCGAATGCGGCAAGGTATTCTCGAATTACGCGAACGTCAGACGACACATACGTAACATCCATAAGACGAATAAGTATCGCGTGATTTGTCCCCAGTGCCCCCGGAAATTTAAGAGCAAGGAGATCTGCAGCAGGCACATTGCGACCGAGCACAAAACTGGCAAGACCATGCGCCAGTGTCCACAGTGCCCGAAGAGCTTTGTCTTCCAAGCGAACCTGAACCTCCATTTCCAGACTGCTCACAAGAACAAGAAAGTCGGTGGCTACGAGTGCGATATCTGCGGCAAGACGTTCCAAGAGGAAGCGTCCCTCAAAATACACCGGGGATGGCACAACAGAACGAACTCCCGGTTGAGCTTGCGGAAACCGCCGGCGCTCGAAGTAGACCGAAAGATTGTCAAAGATCCGTTGGCGATTAAACCTGAAGAGATACACAACGCCAGCCCCGACAAGCCCGCCAGGGCAAGGAAATCGTTCCCCAATTCGGCACCCGTGAAACCGGAGGGTAAATTCCAGTGTCAGGTATGCAACGACAAGTTCAACGATGTCACCGAACTGAGGAAACACTTGTGGGACGTACACTGCGCTCACAAAAGCGAGAAAACGTTCACAAGCGAGGGGCATATCTGCGATATCTGTAGCAATATCTATCCCGACAAAGAGACGCTCGACATTCATATGAACTGGCACAAGTCGTTCACGAGCCTCAGTCGTGTTAGGAGAGCCAGGAACCAGGGTAACTTCCCCTGCGACATCTGCGGAAAATTCTACAGCTCGAAGAAGGTGCTATGGAGACACAAGAAGCTACACAAAGCGACCAGCCTCGCCGCCGCTACGTTGCAGTCGGCGACTAGAAAGCCGATGCCGAATCAGCATATTTGCACCATTTGCCACAAGATCTTCTGCAGCAAACAGTCACTGCAACGTCACAGGATGAACATCCACAGCGAGGTATCCACCCAGCAGCAGCAGACGATATTCTCCAGCAAGAGGAGGGTGTCCCAGGAAGAGCCGAGCCCGAAGAAGCTGAAACTGGAGAAGGAAGAGGAAGTGGAGATCCTGCCGAAACCGAACATGGTCGTAAACACAGTAGCTGGCGGTAAGAAGCCGGTGATGTGCCACGTTTGCAGGAAGTTCTTCGCGAACATGAGCGTGTTGTACAAACATAAACAAGTGGTGCACAGCAAGTCCCGGCTTATGAAGCCCGCGGTGAAAGCGCCCGTGCCCGCGTCGTCGTCCACGATAAACCAATGCATCCCGGTGCCCGGAACCGACGGCAAGGTCTGCTGCAACATCTGCTACAAGGCTTTCCACGCCATACCAAGCTTGCGCCAGCACTTCACCATCAAGCACAAGAACACTCCGCCGAAGTTCGCGTGTCACATCGACGGCTGCAAGATGATATTCCCGTCGTCGGCGACCCTGAGGAATCACGAGGTGTCCCACAACAACACGATCTTCAACTGCAACCTGTGCAGTCGCCATGTGTTCAACAAGCAAGCGATGACCGACCACATGCTGACGGCGCACAACACCGTCTACGACGCTGAAAAGAGCAAGAACTTTCATCGGGAAATGGACCTGACACTCTACGTTGTGGAGAACGCGGTCGACGCAACTTGTCCCCACTGCAAGATCAAGTATCCCAACAACAGGGCCATGAAGATCCATTATTTCAAATTCCACGACTACGCCAACTAA
- Protein Sequence
- MDKVVVLQRMENVCRLCLSEDEPKLSVFGSQETPVSLATKIQACLSIQILATDRLSTQICSQCVKNVNQWHNYKETCLRSQDKLHQWLEKHTQSSPLVVTIKDEPVDLDFYEDNIEVISESSIASELESTNLDESLDDSVNTLHIQEISDDETDDARVPPALTKPFDSCIKSEPPEDCDTDCTIEIESITGSELVLNPLSNKEDRIMEADSTQKSNASASVIKKKLRRGPHTHYRGPRAFKQKCVHCQIFLHSKYTYTKHMERFHSDKQNGNADDQVKVEEEVEDLEDELMSMEKDAPLTQVQQNIISQLKTFSCYSCQQLFSDRRSTLSHIRQHMPDLRPYTCIACLTEFPDRSMYKLHCGASFECAMKIALVIPNQGEEKYFTCNMCLRSMPNRKELLCHLSKHSDKQYQQLVKPSRSPPKLKPISPLPAAKQESPTKKSIAGGPDVPHPYKNGDPAHNHICDLCGMIYRYKPNMLKHKDLCQRLQPDLRISYKCMHCGMTYLVFKKFHNHITQDHKKKDFFCSECGAKFRSPSEFLMHYDGHRGKMNKKPVLEKNDSAAKNAQNFSMPIKDWDTFEAEMNDGRLSDSNQYSCALCNLEFATRAELTEHRNLHLKVKIYSCVICRSMFSSAGALEIHMKDHGIEDPGERNANSSCVEYGTMKDSPEDCKPLNVSATSDPGPKKNECRECGKVFSNYANVRRHIRNIHKTNKYRVICPQCPRKFKSKEICSRHIATEHKTGKTMRQCPQCPKSFVFQANLNLHFQTAHKNKKVGGYECDICGKTFQEEASLKIHRGWHNRTNSRLSLRKPPALEVDRKIVKDPLAIKPEEIHNASPDKPARARKSFPNSAPVKPEGKFQCQVCNDKFNDVTELRKHLWDVHCAHKSEKTFTSEGHICDICSNIYPDKETLDIHMNWHKSFTSLSRVRRARNQGNFPCDICGKFYSSKKVLWRHKKLHKATSLAAATLQSATRKPMPNQHICTICHKIFCSKQSLQRHRMNIHSEVSTQQQQTIFSSKRRVSQEEPSPKKLKLEKEEEVEILPKPNMVVNTVAGGKKPVMCHVCRKFFANMSVLYKHKQVVHSKSRLMKPAVKAPVPASSSTINQCIPVPGTDGKVCCNICYKAFHAIPSLRQHFTIKHKNTPPKFACHIDGCKMIFPSSATLRNHEVSHNNTIFNCNLCSRHVFNKQAMTDHMLTAHNTVYDAEKSKNFHREMDLTLYVVENAVDATCPHCKIKYPNNRAMKIHYFKFHDYAN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00183438;
- 90% Identity
- iTF_00184094;
- 80% Identity
- -