Mgen007619.1
Basic Information
- Insect
- Megalopta genalis
- Gene Symbol
- Hr39
- Assembly
- GCA_011865705.1
- Location
- NW:596278-621106[-]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 5 2.8 8.9e+03 -5.2 5.7 120 159 67 105 23 136 0.42 2 5 2.3 7.1e+03 -4.9 16.8 38 163 344 464 330 485 0.45 3 5 3 9.4e+03 -5.5 10.7 70 160 476 567 454 584 0.58 4 5 4.2e-08 0.00013 20.6 0.0 1 23 650 672 650 681 0.92 5 5 1.7e-70 5.4e-67 226.1 0.1 185 408 806 1025 693 1025 0.89
Sequence Information
- Coding Sequence
- ATGTCGGAGCAAAACGGGCCCAGCGAGGGCCCAGGGCCGGGTCCGGGACCGGGCCCTGGATGGTGGCCTACCTCGCAGTCCTGGAAGTCTagctcggcggcggcggcggctgcggcggcggccgcgtccGCGTCGGTGCCCGCGTCGGGCCCCGGGCCCCTGCCCGCGCCAGCGTCCGCGTCCGCTTCCTCGACCGCCGGCTCCACCGCTCCGAACAGCTCCGACTCCGTCTCTGCGTCCTGCACCGCCGCCTCTACCTCCTCCTTGGCGACCACCGCTTCGCCGGCTCCCTCGTCCAGCTGTTGTTCCTCGACCCCCGGCGGACACGCGTGCACCATCACCGCGGCCCGCACCTCCGAGACCGGCAAGAACGTCTCTGTTACGACCATCAATGTACCTCAGAACCAAGACTTACACGATGGAAAAGGCATATGCAAATACCTTACCGGGCAGAACGGCGTGACAGTGTCCGTGGTATCGAGTTGCGGGTCCGTCCTTGGATGTGGAAACGCGAACGTGGTGTCGACGACGGGAATCGGGAGCGGTTCCGGCATCCATAGCATAGGCATCGGTATCGGAGTCGGAGTCGGCGTCGGGGTCGGTATCCTCGGTCAAAACGCCGCGGAGAACGACGCCGAGGACAGCGACGGCGAGATAAGCAAGATCGATTTCCGAGGCGTGAATTTACGTACAAAGAAGAAACGGGATGTGTCCGGGAACGGCGAGAAGATCGGCGACGGGGACGTCGACGATGGGAACGGCTGCTACGACGGTAACGACGTTTCGCAGCAGCAGCCCGAGAGACCCATGTCGTGGGAAGGGGAATTGTCGGATCAAGAAATGTCTTCCAACACGATCACGAATCAGGACACGCACGAGGAAACCTCGATGGAAGGTGTCCAGGTTTGCGGTTCGAGTCCTGGACCCATGGAGCAGAAGTTCCCTATAAAACCGGAACCGGATTTCCGATCCAGCCCAGGATTCGCGTTAGGTTCCTTTCACGATGCAGGAGCGTCGCTGGCCCACGGTCAGCAGatgcagcaacagcaacaacaacagcagcaacagcagcagcaacaacaacaacagcaacagcgaACAATAGAGAACATCGAACAGACGCAGCAGAGCGATTTGCCTCTTTTGGTGGGGAAACTGCTCGGCGGTTACAATAGCTCCACCCCGAATCACAGTCCGGTATTGAACCCGAGACATCATTTGACCAAGCATAGCCACACGAGATCTCAGGTGCCGTCACCGGATTCCGCGATTCACTCGGCGTACAGCGTGTTCAGTTCGCCGACGCAGAGTCCTCACGCGGCTCGGCACTCCGCTCTAGGAGCAGGAAGCCCGGTCCCTTCGTCGTCGCTCTCCTTGTCCCGGCACAGCTTCAACAACTCCACCTCCTCGTTGTCACTGTCCCTGTCGCACTCGCTGTCCAGAAACAACTCGGACGCATCGAGCAGCTGCTACAGCTACGGCTCCCTCAGTCCGCCCACGCATTCTCCCGTCCAACAACCGAGGCATCCGCAGCACCATCAGCACCAGGTTGCTCAAGGAAGTCCTCTCCACTTGCCGGCCACGGCCACGTCCAGCGTGTCCCATCACTCTTATTCCTCTTCCGTGCCCGGTTCCGAGCTCTCTCCCGAAGCGCACGCCGCCGGAGACGACCAGGAGGACTGCCGAATACCCTCGGCCCCCTCCGGCATCTCGACCAGACAGCAGCTGATCAACAGTCCCTGTCCGATCTGCGGCGACAAGATCAGCGGTTTTCATTACGGCATCTTCTCCTGCGAGTCGTGCAAGGGCTTCTTCAAACGCACCGTCCAAAACCGGAAGAACTACGTGTGCCTTAGGGGCGCCGGTTGTCCGGTCACCGTCGCCACCAGGAAGAAGTGTCCGGCCTGTCGATTCGACAAGTGCCTCAACATGGGTATGAAACTCGAAGCCATCAGAGAAGACCGTACCAGAGGCGGTAGAAGCACCTACCAATGCACCTACACTCTGCCGGCGAGTCTGGTCGGTAGTCCTGCCAGCGGCATGACGGGCGACAAGCTAGGCGTCGGCGGAAACTGTAGTCCGGCACCGGCTGGCAGCGAGCATCATTATTCCGCCAGGCATCATTCGAATCACTCGCACAAGATGCAGGTGGTGCCGCAGCTTCTGCAGGATATCATGGACGTGGAACACCTGTGGCACTACAACGACAACGACCGAATGTCCGGCGTTCAACCGGGAGGAGGAAACGTCACCAGAAACAACGATGCCATGTTACTGGGGGGCGTAGGACCGGCGACCGGGAACGACGCCGGCTCGGGAGTCGAGTGTTCGTCGAACGGCACGGCGGGGAATGGGAATTTGAACAACAGAAGAGACGGCAGGTCGTGTCCGAATATCGCTAGCGTGAACAACGACCAACGGGCCCCGCCGGTCAACAGCAATTCCCAGTTGGGGAACAACGCGAACGGCAATCCTACTCAGCATCCCGATTTCCTCTCGAACCTTTGCAACATCGCGGACCATCGACTCTACAAGATAGTGAAGTGGTGTAAAAGTCTGCCGTTGTTCAAGAACATCTCTATCGACGACCAGATTTGCCTTTTGATCAACTCCTGGTGCGAGCTGTTGCTCTTCTCGTGCTGCTTTCGCAGCATGAGCACGCCCGGTGAAATTCGAGTGTCTCTCGGCAAGTCGATCACCTTGGAACAAGCCAGGCAGCTTGGCCTGGCGACCTGTATCGAGAGGATGCTCGCGTTCACCAATAATCTGAGAAGGCTCAGAGTGGATCAGTACGAATACGTTGCGATGAAGGTGATAGTACTGTTAACATCCGACACGAGCGAGCTGAAAGAACCGGAGAAAGTGCGAGCATCGCAGGAGAAGGCTCTTCAGGCCTTGCAGCAGTACACAATAGCAAGGTATCCCGAGATGCCTGCCAAGTTCGGCGAACTGCTACTCAGAATTCCAGACTTGCAAAGGACGTGTCAGGCAGGGAAGGAATTGCTGAGCGCAAAACGCGCGGAAGGAGAAGGCAGTTCGTTCAACTTGCTGATGGAATTGTTGAGAGGAGATCATTGA
- Protein Sequence
- MSEQNGPSEGPGPGPGPGPGWWPTSQSWKSSSAAAAAAAAAASASVPASGPGPLPAPASASASSTAGSTAPNSSDSVSASCTAASTSSLATTASPAPSSSCCSSTPGGHACTITAARTSETGKNVSVTTINVPQNQDLHDGKGICKYLTGQNGVTVSVVSSCGSVLGCGNANVVSTTGIGSGSGIHSIGIGIGVGVGVGVGILGQNAAENDAEDSDGEISKIDFRGVNLRTKKKRDVSGNGEKIGDGDVDDGNGCYDGNDVSQQQPERPMSWEGELSDQEMSSNTITNQDTHEETSMEGVQVCGSSPGPMEQKFPIKPEPDFRSSPGFALGSFHDAGASLAHGQQMQQQQQQQQQQQQQQQQQQQRTIENIEQTQQSDLPLLVGKLLGGYNSSTPNHSPVLNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAARHSALGAGSPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRHPQHHQHQVAQGSPLHLPATATSSVSHHSYSSSVPGSELSPEAHAAGDDQEDCRIPSAPSGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPASLVGSPASGMTGDKLGVGGNCSPAPAGSEHHYSARHHSNHSHKMQVVPQLLQDIMDVEHLWHYNDNDRMSGVQPGGGNVTRNNDAMLLGGVGPATGNDAGSGVECSSNGTAGNGNLNNRRDGRSCPNIASVNNDQRAPPVNSNSQLGNNANGNPTQHPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGSSFNLLMELLRGDH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00733987;
- 90% Identity
- iTF_00763268;
- 80% Identity
- iTF_00966053;