Mdil028469.1
Basic Information
- Insect
- Megalocaria dilatata
- Gene Symbol
- Hr39
- Assembly
- GCA_034642435.1
- Location
- CM067860.1:34390524-34403862[+]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.13 1.8e+03 -0.8 4.7 51 132 185 268 89 302 0.70 2 4 4.5e-08 0.00062 20.5 0.0 1 23 372 394 372 400 0.89 3 4 0.0076 1e+02 3.3 0.0 66 120 410 461 390 478 0.59 4 4 9.1e-73 1.3e-68 233.6 0.2 205 408 501 699 484 699 0.97
Sequence Information
- Coding Sequence
- ATGGCCGCCGAGATGAGGTCCCCCAATATATCAGTCACTCCAATCAATGTGGAGGTTTACCATCATCCAGTTCCCTCTTCCAACCCGTCGTCCGGTGAGCCACCGCCAGACGGCGCAGACGCGGAGGTTGCTCGTATCGAGTTCCACAGTTCCGTGAACATGCGCAGTCGAAATGAAGAAGAAGGGGGAAGCCATCCGCCGCGGCCGATGTCTTGGGAGGGAGAGTTATCGGACCACGAGAGGGATATGTGCGTGGATGAAGAGTCTACGCATCAGATCCCAGAGAATCTTTCCATATCTCAACAAACGAAACAAACATCAACCATCATCGTAGATTCTAAGGATAGTCCCATACTGAGGTTAAAACAACCACCGATGGGCAATTATTCACTACATAGCACCCCCAGCCATTCACCCCTGCTAGGACAACGTCACCCCATCACCGGAGTTCCGATGATGAGCCATAAAGACATGATGCACAAAGCCCTCAACGTTCCACCAACCCCAAGTCCCGACTCTGCTATCCATTCCGCCTATAGTGTGTTCAGTTCGCCTAATCAGAGTCCTCTTACTCAAAGACACATAAACTTAACTCCAAATTTGAGTCGGAATAATAGTGATGCTTCGCATTCCAGTTGCTGCAGCTATTCAAGTGTTTCTGTTTCAGTGTCACCTACACAACAGTTTTCGCCAACTCATAGCCCTATTCAGGGTCGTCACATGCATAATGTTCACGGCAGCCCTCTACATCACAACGTACTCTATCGAAGTCTCCAAGAAGACTCGCCCTCGCCATATACAAACGAAAACGATGGCCTAGATGAAGTAGAAGAAAAGACTGGCCTACTCCATACTTCACTGCCCGCACAGCCCGGTATCTCGAGACAACAACTAATCAACAGTCCCTGCCCCATATGTGGAGACAAGATATCTGGTTTTCACTATGGAATTTTTAGCTGTGAATCATGTAAAGGTTTCTTTAAGAGAACAGTACAAAACCGAAAGAACTACGTCTGTTTGAGAGGCGCTTCTTGTCCAGTTACGGTGGCCACAAGAAAAAAATGTCCTGCCTGTAGATTCGAAAAGTGTTTGCAATGTGGTATGAAGTTGGAAGCCATCAGAGAAGACAGAACAAGAGGTGGACGCTCAACATACCAATGTTCGTATTCTCTTCCGCCATCATTGACAAATCATTCCGATTTTAGAAATAGTTCCTCCGATTTACGACATAGTATGAACGATCATTCCTTAACCGTTAAATTGGAACCTCCAGAATTTGGTAGTAGTCATCATAGACGAAGTGCAATACCAGGTTCTAAAGGTGTCCCACCATTATTACAgGAAATAATGGATGTGGAGCACCTTTGGCATTACAACGAATCTGaacttcaaaaactcaacacaGAAGGACATTTAGGTAAAGAAGGTGGTAGTGGAGCAGTGCATAATTTGGCCAATCATCCTCTTCTAGCGGGTACAGCCCTAGCAGGTTCAACTGAAACCAGTCCTGACTTCGTTGCCAACCTTTGCAATATTGCTGATCATAGGCTGTATAAAATAGTGAAATGGTGCAAAAGTTTGcccttattcaaaaatatttctatcgatgatcaaattTGTCTCCTTATTAATTCCTGGTGTGAGCTACTCTTATTCTCGTGCTGTTTTCGATCCATGTCAACGCCAGGAGAAATAAGAGTGTCTCTCGGAAAAAGCATCACTCTGAGCCAAGCTAGGGAAATGGGCATGCAGGCATGTATAGAAAGAATGTTGAATTTCACTGAACAACTGAGGAGACTTAGAGTGGATCAGTACGAATATATTGCCATGAAAGTCATTCTTCTTCTAACTTCAGaTACTTCCGAACTAAAAGAAGCCGAAAAGGTTAGAATATCGcaagagaaagcattgaaagcTTTGCAAGATTATACCCTTGTTCATTATCCAGAAAGTCCTTCTAAATTTGGAGAACTGTTACTTCGAATACCTGAACTACAACGAACCTGTCAGGTTGGGAAGGAAATGCTAACAATTAAATCAAAAGATGGGGATGGACCGAGCTTCAATTTACTGATGGAGCTCCTCCGCGGGGACCACTaa
- Protein Sequence
- MAAEMRSPNISVTPINVEVYHHPVPSSNPSSGEPPPDGADAEVARIEFHSSVNMRSRNEEEGGSHPPRPMSWEGELSDHERDMCVDEESTHQIPENLSISQQTKQTSTIIVDSKDSPILRLKQPPMGNYSLHSTPSHSPLLGQRHPITGVPMMSHKDMMHKALNVPPTPSPDSAIHSAYSVFSSPNQSPLTQRHINLTPNLSRNNSDASHSSCCSYSSVSVSVSPTQQFSPTHSPIQGRHMHNVHGSPLHHNVLYRSLQEDSPSPYTNENDGLDEVEEKTGLLHTSLPAQPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGASCPVTVATRKKCPACRFEKCLQCGMKLEAIREDRTRGGRSTYQCSYSLPPSLTNHSDFRNSSSDLRHSMNDHSLTVKLEPPEFGSSHHRRSAIPGSKGVPPLLQEIMDVEHLWHYNESELQKLNTEGHLGKEGGSGAVHNLANHPLLAGTALAGSTETSPDFVANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLSQAREMGMQACIERMLNFTEQLRRLRVDQYEYIAMKVILLLTSDTSELKEAEKVRISQEKALKALQDYTLVHYPESPSKFGELLLRIPELQRTCQVGKEMLTIKSKDGDGPSFNLLMELLRGDH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00753059;
- 90% Identity
- iTF_00764767;
- 80% Identity
- iTF_00965262;