Basic Information

Insect: Megachile ligniseca
Gene Symbol: Hr39
Assembly: GCA_945859565.1
Location: CAMAOB010000012.1:5170604-5176177[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 1.6 9e+03 -4.0 6.5 120 156 49 85 17 110 0.49

2 4 0.67 3.8e+03 -2.7 4.3 73 163 309 397 251 418 0.63

3 4 4 2.3e+04 -8.0 11.6 70 160 432 521 406 539 0.47

4 4 2.2e-75 1.2e-71 242.6 0.7 1 408 604 982 604 982 0.79

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	1.6	9e+03	-4.0	6.5	120	156	49	85	17	110	0.49
2	4	0.67	3.8e+03	-2.7	4.3	73	163	309	397	251	418	0.63
3	4	4	2.3e+04	-8.0	11.6	70	160	432	521	406	539	0.47
4	4	2.2e-75	1.2e-71	242.6	0.7	1	408	604	982	604	982	0.79

Sequence Information

Coding Sequence: ATGTCGGAGCAAAACGGGCCCAGCGAGGGCCCAGGACCAGGACCAGGACCAGGCCCCGCTTGGTGGCCAGCCTCGCAGTCCTGGAAAACGAACTCCTGTGCATCCGTCTCCTCATCCAGTACTTCCACTGCTCCAGACAGCTCCGCCTCCGTCTCTGTATCCTGCACCATTTCTACCTCTTCCCTGACGACTACCACTTCGACTACTTCCTCGACAAGTTGCTGTTCCTCGACTCCTAGCGGACCTTCGTGTACGATCACGGCTGCCCGTTCCACGGAAACAGGAAAGAACGTTTCTGTCACCACGATTAACGTACCGAACAATCAGGATATACATGATGGCAAAGGCATTTGTAAGTATCTAACCGGCCAGAATGGCGTCACAGTGTCCGTAGTTTCAAGCTGTGGCTCCGTATTGGACTGTGGAAATGCGAATGTTGTATCCACCACAGGGATTGGCATCAATAACGCCTCGCACAGCATCGGGATTGGCATTGGAGTTAATGTCCTTCAGTCTCAAAACACTGCAGATGATGATGCAGAGGATAGCGACGTAGAAATAAGCAAGATTGATTTTCGTGGAGTGAACTTACGTACGAAGAAGAAACGAGACGTGCCGGGGAACCAGGGTGGAGAGAAAATAGGTGACGGAGATACCGAAGATAGAAATGGTTGTTACGATGGAAATGATATCTCCCAGCAACAACCAGAAAGACCCATGTCATGGGAAGGTGAATTGTCTGACCAAGAAATGTCTTCCAATACAATTACAAATCAGGATACACATGAGGACACATCCATGGAAGGTGTCCAAGTATGCGGTGCGAGTCCGGGCCCTATAGAGCAAAAATTTCCTATAAAACCAGAGCCTGACTTTCGGTCTAGTCCTGGATTTGCATTTGGTTCTTTTCATGATACTGGATTACCTTTGGCACATGGCCAACAGATGCAACAACAACAACAACGCAACATAGAGAACCTTGAACAGACACAACAAAATGATTTGCCTCTTCTCGTAGGAAAACTACTGGGTGGTTACAATAGTTCAACTCCAAATCACAGTCCAGTTTTAAATCCCAGACATCATTTGACTAAACATAGTCATACGAGATCACAGGTGCCGTCTCCAGATTCCGCAATTCACTCGGCATACAGCGTATTTAGTTCGCCAACACAGAGCCCTCACGCAGCTCGCCATTCTGCTTTAGGAGCAGGAAGTCCGGTACCGTCTTCGTCGCTTTCTCTCTCGCGACACAGCTTCAACAATTCAACTTCCTCTTTATCGTTGTCACTATCGCATTCTCTCTCGAGGAACAATTCGGATGCCTCAAGCAGCTGTTACAGCTACGGTTCTCTTAGCCCACCTACGCATTCACCCGTCCAACAACCAAGACATCCACAACATCATCAGCACCAGGTGGCCCAGGGAAGTCCGCTTCATCTACCAGCAACAGCCTCGTCCATTGCTCATCATTATTCTTCCTCTACACCGGGTTCTGAACTCTCCCCTGAAGGACATACCGCTCCTGATGATCAAGAAGACTGTCGAATACCCTCAGCTCCTTCCAGTATCTCCACTAGACAACAACTGATCAATAGTCCATGTCCAATTTGTGGTGATAAGATCAGCGGTTTCCATTATGGAATCTTCTCGTGTGAATCATGTAAAGGATTCTTTAAACGCACCGTCCAAAACCGGAAAAATTATGTGTGCCTTAGAGGCGCGGGCTGTCCAGTCACCGTTGCCACCAGAAAGAAGTGCCCAGCCTGTCGTTTTGACAAGTGCCTCAATATGGGTATGAAGCTTGAGGCTATTAGAGAAGATCGCACCAGGGGCGGACGAAGTACCTATCAGTGTACGTACACTCTTCCAGCAAGTCTTGTGAGTAATTCTGCGAGCGGTATGACTAGTGACAAATTGGCTACGGGAGGGAATTGTAGTCCAGCTCCATCGGGTAGTGAACATCACTATCCCAGTAGACATCACTCGAATCATTCGCACAAGATACAGGTGGTGCCGCAACTTTTGCAAGACATTATGGACGTAGAACATTTGTGGCATTACAATGACAATGATCGCATGTCTGGAATTCAAGCTGGAGGAATGAATGCTACCAGAAATAACGATACGATGTTATTGGGAGTTGGTTCCGGAACTGGTTCTGGATCCGGAACAGGAAGTGACGGAAGTGTTGAGTGTCCCTCCAATGGAACAGCTGGAAATGGAAATTCCAACAACAGGAGAGACGACAGATCATGTTCTAATGTTTCTGCTGTTAATAACGAACAACGAGCTACATCTGTTACTAGTAGTTCCCAGATTGGTAGCAATACGAATGGCAATTCTACCCAGCATCCTGATTTCCTATCGAACCTTTGTAACATTGCTGATCATCGATTGTATAAAATAGTGAAATGGTGCAAGAGTCTGCCGCTGTTTAAAAACATTTCCATTGACGATCAAATCTGTCTGTTAATTAATTCCTGGTGCGAGCTATTGCTCTTCTCGTGCTGCTTTCGCAGTATGAGTACTCCCGGTGAAATCAGAGTGTCTCTGGGCAAGTCGATTACATTAGAGCAGGCTAGACAGCTTGGCTTAGCGACTTGCATCGAGAGGATGCTCGCATTTACTAACAATTTGAGAAGGCTAAGAGTGGATCAATACGAATATGTCGCGATGAAGGTAATAGTGTTGTTGACCAGTGATACAAGTGAATTGAAGGAACCTGAAAAGGTTAGAGCATCTCAGGAAAAGGCGTTACAGGCATTGCAACAATATACCATAGCAAGGTACCCAGAGATGCCTGCCAAATTTGGCGAGTTATTGTTAAGAATTCCAGATTTACAAAGAACATGCCAGGCAGGAAAAGAATTGTTAACTGCAAAACGTGCAGAAGGTGAAGGCAGCTCGTTTAATTTGTTGATGGAATTATTAAGAGGAGATCACTGA
Protein Sequence: MSEQNGPSEGPGPGPGPGPAWWPASQSWKTNSCASVSSSSTSTAPDSSASVSVSCTISTSSLTTTTSTTSSTSCCSSTPSGPSCTITAARSTETGKNVSVTTINVPNNQDIHDGKGICKYLTGQNGVTVSVVSSCGSVLDCGNANVVSTTGIGINNASHSIGIGIGVNVLQSQNTADDDAEDSDVEISKIDFRGVNLRTKKKRDVPGNQGGEKIGDGDTEDRNGCYDGNDISQQQPERPMSWEGELSDQEMSSNTITNQDTHEDTSMEGVQVCGASPGPIEQKFPIKPEPDFRSSPGFAFGSFHDTGLPLAHGQQMQQQQQRNIENLEQTQQNDLPLLVGKLLGGYNSSTPNHSPVLNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAARHSALGAGSPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRHPQHHQHQVAQGSPLHLPATASSIAHHYSSSTPGSELSPEGHTAPDDQEDCRIPSAPSSISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPASLVSNSASGMTSDKLATGGNCSPAPSGSEHHYPSRHHSNHSHKIQVVPQLLQDIMDVEHLWHYNDNDRMSGIQAGGMNATRNNDTMLLGVGSGTGSGSGTGSDGSVECPSNGTAGNGNSNNRRDDRSCSNVSAVNNEQRATSVTSSSQIGSNTNGNSTQHPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLTAKRAEGEGSSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00733987;
90% Identity: iTF_01122467;
80% Identity: iTF_00964514;