Basic Information

Insect: Megachile leachella
Gene Symbol: -
Assembly: GCA_963576845.1
Location: OY756252.1:3441640-3448321[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.63 94 4.7 0.4 1 23 79 104 79 104 0.97

2 17 0.0023 0.34 12.4 1.7 2 23 117 138 117 139 0.95

3 17 5.3 7.9e+02 1.8 3.7 1 23 145 167 145 167 0.97

4 17 0.034 5 8.7 0.5 2 23 173 194 172 194 0.97

5 17 0.19 28 6.3 8.5 2 21 471 490 470 493 0.94

6 17 2.2 3.3e+02 3.0 1.0 1 23 558 580 558 580 0.82

7 17 0.057 8.5 8.0 0.2 1 23 789 811 789 811 0.94

8 17 0.005 0.75 11.3 0.3 1 23 819 841 819 841 0.98

9 17 0.16 23 6.6 3.1 2 23 937 958 936 958 0.95

10 17 0.097 14 7.3 0.5 3 23 970 990 968 990 0.96

11 17 0.0031 0.46 12.0 0.2 1 23 1067 1089 1067 1089 0.98

12 17 0.083 12 7.5 0.3 1 23 1163 1185 1163 1185 0.97

13 17 5e-05 0.0075 17.6 0.6 1 23 1191 1213 1191 1213 0.97

14 17 0.0052 0.77 11.3 2.6 1 23 1269 1291 1269 1291 0.97

15 17 0.00084 0.13 13.7 1.7 1 23 1297 1319 1297 1319 0.99

16 17 0.24 36 6.0 2.0 2 23 1411 1432 1410 1432 0.97

17 17 7.7 1.2e+03 1.3 0.3 2 23 1440 1461 1440 1461 0.79

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.63	94	4.7	0.4	1	23	79	104	79	104	0.97
2	17	0.0023	0.34	12.4	1.7	2	23	117	138	117	139	0.95
3	17	5.3	7.9e+02	1.8	3.7	1	23	145	167	145	167	0.97
4	17	0.034	5	8.7	0.5	2	23	173	194	172	194	0.97
5	17	0.19	28	6.3	8.5	2	21	471	490	470	493	0.94
6	17	2.2	3.3e+02	3.0	1.0	1	23	558	580	558	580	0.82
7	17	0.057	8.5	8.0	0.2	1	23	789	811	789	811	0.94
8	17	0.005	0.75	11.3	0.3	1	23	819	841	819	841	0.98
9	17	0.16	23	6.6	3.1	2	23	937	958	936	958	0.95
10	17	0.097	14	7.3	0.5	3	23	970	990	968	990	0.96
11	17	0.0031	0.46	12.0	0.2	1	23	1067	1089	1067	1089	0.98
12	17	0.083	12	7.5	0.3	1	23	1163	1185	1163	1185	0.97
13	17	5e-05	0.0075	17.6	0.6	1	23	1191	1213	1191	1213	0.97
14	17	0.0052	0.77	11.3	2.6	1	23	1269	1291	1269	1291	0.97
15	17	0.00084	0.13	13.7	1.7	1	23	1297	1319	1297	1319	0.99
16	17	0.24	36	6.0	2.0	2	23	1411	1432	1410	1432	0.97
17	17	7.7	1.2e+03	1.3	0.3	2	23	1440	1461	1440	1461	0.79

Sequence Information

Coding Sequence: ATGTCAGGAAGGCTACCTCGATTGCGTGCACTTCGTCCGCGGCCTCAACAATCGAAAACTGAACTGCACAAGGAAAGTAACCTTAAAGAGGCTAGACAGGAAGTCGCGATGAGGGAACATGAGTTACGGGACAATAGCGAAGAAATTTCGTACGACGTTAAAGACAATAACTCTATGAGGAACAATTTAAAACGTGAACACGAGGCATTCGATTGTTCAGGAACTTCTCAAAATTACGAATGCAAAACTTGTAAACCTCCAAAGTCTCTCTCCAGTCTAAAAGCGTATCTCGATCATTTGAAAAAAGAACATAAACAAAAGggAAAATTTATACGTGATAGTGGAAATCGATGTTCCATGTGTTCGTACGTTTCAATAAATTCAAGGGATCTTGAAACTCACCAGAGAGTTCATCATTTGAAAAGAAGATTCTTTAGATGCGCCAAATGTTCTTATGTAACCCACGTACGTGCTCGTTACACGAAGCATGTAAAATACCATTCTATGCCGATGATTAAATGTGATGCTTGTGACTTTCGTACTCCATACAAGTGGAATTTGGACAGGCACACCAGGAATCACGGAGGAGGAGGAGCTTTTCAATGCCGTGCTTGCAATTTTACAGCTGATATTAGGCAGAGTTTAACAGTACACGAAACTAATCATCATGAACCTCCTGTGAGTCAAACAAACCGCAAATCTAATGCACCTTATGAGCGTAAACCAAGAAATAGTCCTAAGCGTTACAATCAGGTCGGTGCAAGTGATTTTCGGGATTCGTTACGAATATCTGGAAGTACAACTGTATCAATCAGTCCCGGAGATTCGTACGTTTCCGATCAATCTCTAGAAGATAAAAGAAACGCGATGGCCAGTGCCGAATGTATAGCGTTAAAATGCGAAGAAAAAGGGTGTCAATTTATTACAGCATGGGATTCTGAAATGCAACGACATTTAGCAGAATGTCATGCTCCAGTTACACCAAATAAATCTAAAAAGCCACTGCCAATGTTAATTCCTTTAAGTCCTGCTAAATCTGGCAGCTGCAGTACCAGTGGATCTTCGACGACATTATTAAAAGTTCCGCGTGTGAGGGTAAGACCGGAACTTGCACAAATCGCAAGAGATACGGAACTAGCCAAATTATACGGAAATAAAGAAGTCAGAAATTTAAAGAAGGATGCAAATAATGCGGCagatttatttgaaaaaaaaaatgcgtCCTTCTTTGATAAGCTAAAGGAAAAGCTTACAACGTCGGCGTCAATTAATAATGGAGTACCAGAGGTAGCTGTAAGTACTACGAACGATTTGAAATGCTGGTGTACTTTTAAAGCTAGTAGCATGGAAGAGCTGGCTTGTCACAAACAAACACACCACACCGCTCTCAGTGTATCTGTGGGTACAACGCGTTGTCCCAAGTGCAGAAGACGTTGCAAAAGTTCGACTGATCTACAAGTGCATATGCAGTGTTGTCACTCGACAAGCAACAATACGTCCATTCACAATAGCTtagaaaaattatcaaattgttcaGAACTCCGTGTGACCTCGTATCGCGGTGAATATGCATTACCTGCGCAAACGGATTGGGACATTAATCTCAGCGGACTGAATTCTTCTGGATCATCGGTTGAAGGCTCCTCGACGCATCCATGTGGCCGACGGGTATTTAAATGCCCGCACTGTCCATTTTGGGCATCCACCGCAAGTCGTTTTCATGTTCATATTGTCGGTCATTTAAATCGGAAGCCATTCGAGTGTTCCCTATGCGCGTATCGCTCTAACTGGCGATGGGACATCACAAAACATATTAAACTTAAAGCAGCTAAAGATCCAGTTCATATGACTGCCACGGTACTTATGACGGATGAAACAGGTCGACGGAATTATTCCAAATATAACAAATACCTTGCACAGGTCGAGCAACAGTCGTGGGACGATCAAACCATGGAGGAACATAATACAGAAGACACACAGTCTGACGAGCCACCAACTAAGTTGTTGATAATGAACTCCAATGAATATCTGCAAACATCAGAACTTACTACTCCCGTTTCAATTATGTCTGCAAGCGATACAAGTCATAACGTTAACGCTATAAATGCCGCGTTGAGACCACCTCCGCCTCTCAAAGCCGCTGCTAGAAATCGTGGGCAATCGttgcttaaaaataatttgatttcTCCGAATGCACAAAGTGGAGCAGGCACGTCTACCTCTACTACGGTCACGGAAGAAAATAAACGCACCATGTGGAAGTGTAAGCGTTGTAATTTTCGACATTCCAATAGAGAAACCGTATCGTTGCACGTTAAGTCCCACAATGAGTCAGAACAACGTTACGAAGAAGAAAAGAATGCATTTAATTGCGGAGATTGTCCATACTCTGCATCCGACGCCGCTAGTTTATCTATGCACAGAGTCCATCATCGTCCAAATCTGGAagcaattttcaaatgttatttATGTCCATATTACGTTAGCACAAAAGCAGAGCTTTTGGATCATGTTAGACTGCACGGGGAAGAACTGGCTGTTGTACATCAACAAAATATGGATTATAATTTTTCACCTACTAAATCTAAAACACAAAGTTtaagtattgataataATACAAATCGCACAAAAGTAGAGAAGTGTGTGGAACaagtaatacatataacaaCGCAGAACAACGTGACTTGTGTCAGCGGTGCCTCAAAGAGTTCCAGCGCACCGCCGCCATTACTACTGGACACTCGAGCGTTGCCCGAAGCTCCGTTAGTGTGGGTGTCCCGACCGGATGGTACGCTTACAAAGATGTTAAAATGCCGCCACTGCCCGTTCGTGTGTTCGCGACGTGCCGAAGTCCGGGATCACGAAACCATGCATCTCGATTCTCCAAGCAGTGGTCCTGTGATCGCCTGTACGGATTGTAGTTTCACTTGCACTCGAAGAGAAGTGATGGTTGCCCACATAGACATGCATTCCGGTTCTCTAGGCACCGTTCATTGTTTAGTAGACGATTCTAGGCCAGATTCGCAGCAATTAATCGATTTGACCGCGCTTCTCGGATTTACGCATTCCCCTGTATTGGGTTCGGAACCTGATCTGCGAGACTCGAGACTCGTGCATTGCTGCAGTAAATGCCCAGCACGATTTCTCTGTGAGAAAGAACTGAGGATTCATTTGCGATATCATTCCACGGAATTGGCTTACTCTTGCCAGTGGTGTTCGTACGCTGCTCGACAACCGGCTCATCTTCTAGCTCATCAGAAAGCGCACTCCACCGAGTACCAAGAACGCACTAAATATTTGTTGTCTCTCTACGGTCATTCGCAACGATACCCACCTCCTACCACAGCCTGCGTCGAAACAAATGGCCAGGGCGCAAACAACTCGTCGCCTACCGTCGCCTGGATCGTTGTCGAAATTACCGAAAGTTCAAACAGCAGTTTCAACGACAGCGCGAGCAGCACGAATCAACGAACCGGGAACCAAGTGTTCACATGTGCCAAATGCCCGGCCCGTTACTTCAAGATGGACGCTTTGGAGTACCACATGACTCTCCACGGCTCTAACAACAGATTCAAGTGCACCGAATGCGACTACTCGTCGAAAACTGCTCAGAATCTGGTGAAGCATCAGGTGGTTCATCGTCGTCAGAACGAAACTGGTGAAACAACCTCGAATTTGTCGACGTCATTGCCGCCGCAGCCGCCTCCGCCTCCCCCTGACCCGCAATTCGGAATCTTCATGCGTGGCAATCCGAACTTCGTGTATCCCGGTTATCTGAGGAACGGTCGTTTGAAAGAGAAGCGATACAAATGTCACAAATGTCCCTCGGCCTTCGAGAAACGAGAGCAATACAGAGTGCACTTAACGCTGCACGGAGCGAAGCAGAGATATCGTTGCGACACTTGCGACTACTCCGTTAAGTATTACGCTAATTATATTCAACATCTGAAGAAGCATCAAGCGAACGCCGAAGCGCAGGCCTCGCGCAGGCAATTCGAGGACGATACGATTACCATTGACAGCGATACGATTTCCGACAACAGAGAGTCTGTGTCCCGTTCAGGAAAGACTCTCAAGTCGTCGAGTAACTCGTCCGCCTCGGTGTCCACGAATGGTTTATCGATATTGAATTATGGCGGAGTTCAAGCATCGAATCAGGACAAGCAGTCTTTAATGTTGTTGCAGAAGAAAGGTATACTCGTGTCTTCCAACGACGAAGTCGAAACGTTACGCTGCCAGAGCTGCCCGTTCTCCACCTGTGACAAAGACGCGATGGATGCTCATAAGCGTCGTCACGGTATCGAGAGAATGACTCCATCCTGTCCCCACTGCGATTACATCCCTCGAAAGGACGAGAACGTCGGAGAGCACATAAGACTACATTTCACAAGACTTTATAAACCGGAATCCTATCTTATAATAGAGCTTCTAACTTTAACCATGAAAAAGATAGCTTCAAATGGAAAGGAAGAGAAGCAGAAGGCTGCCGAATTACTTTTTAAAGAGTACGCGGACGGGAGATTTTTTCCATTCGCTGACACCAACTCTTTTGGTAGTCCCTCGACGGTCAACAGCCACAAGGAGAAGGTTATAGTAGATCCAAATACTGGAGAAACGAAACACCGTTTTGCTGTTTAA
Protein Sequence: MSGRLPRLRALRPRPQQSKTELHKESNLKEARQEVAMREHELRDNSEEISYDVKDNNSMRNNLKREHEAFDCSGTSQNYECKTCKPPKSLSSLKAYLDHLKKEHKQKGKFIRDSGNRCSMCSYVSINSRDLETHQRVHHLKRRFFRCAKCSYVTHVRARYTKHVKYHSMPMIKCDACDFRTPYKWNLDRHTRNHGGGGAFQCRACNFTADIRQSLTVHETNHHEPPVSQTNRKSNAPYERKPRNSPKRYNQVGASDFRDSLRISGSTTVSISPGDSYVSDQSLEDKRNAMASAECIALKCEEKGCQFITAWDSEMQRHLAECHAPVTPNKSKKPLPMLIPLSPAKSGSCSTSGSSTTLLKVPRVRVRPELAQIARDTELAKLYGNKEVRNLKKDANNAADLFEKKNASFFDKLKEKLTTSASINNGVPEVAVSTTNDLKCWCTFKASSMEELACHKQTHHTALSVSVGTTRCPKCRRRCKSSTDLQVHMQCCHSTSNNTSIHNSLEKLSNCSELRVTSYRGEYALPAQTDWDINLSGLNSSGSSVEGSSTHPCGRRVFKCPHCPFWASTASRFHVHIVGHLNRKPFECSLCAYRSNWRWDITKHIKLKAAKDPVHMTATVLMTDETGRRNYSKYNKYLAQVEQQSWDDQTMEEHNTEDTQSDEPPTKLLIMNSNEYLQTSELTTPVSIMSASDTSHNVNAINAALRPPPPLKAAARNRGQSLLKNNLISPNAQSGAGTSTSTTVTEENKRTMWKCKRCNFRHSNRETVSLHVKSHNESEQRYEEEKNAFNCGDCPYSASDAASLSMHRVHHRPNLEAIFKCYLCPYYVSTKAELLDHVRLHGEELAVVHQQNMDYNFSPTKSKTQSLSIDNNTNRTKVEKCVEQVIHITTQNNVTCVSGASKSSSAPPPLLLDTRALPEAPLVWVSRPDGTLTKMLKCRHCPFVCSRRAEVRDHETMHLDSPSSGPVIACTDCSFTCTRREVMVAHIDMHSGSLGTVHCLVDDSRPDSQQLIDLTALLGFTHSPVLGSEPDLRDSRLVHCCSKCPARFLCEKELRIHLRYHSTELAYSCQWCSYAARQPAHLLAHQKAHSTEYQERTKYLLSLYGHSQRYPPPTTACVETNGQGANNSSPTVAWIVVEITESSNSSFNDSASSTNQRTGNQVFTCAKCPARYFKMDALEYHMTLHGSNNRFKCTECDYSSKTAQNLVKHQVVHRRQNETGETTSNLSTSLPPQPPPPPPDPQFGIFMRGNPNFVYPGYLRNGRLKEKRYKCHKCPSAFEKREQYRVHLTLHGAKQRYRCDTCDYSVKYYANYIQHLKKHQANAEAQASRRQFEDDTITIDSDTISDNRESVSRSGKTLKSSSNSSASVSTNGLSILNYGGVQASNQDKQSLMLLQKKGILVSSNDEVETLRCQSCPFSTCDKDAMDAHKRRHGIERMTPSCPHCDYIPRKDENVGEHIRLHFTRLYKPESYLIIELLTLTMKKIASNGKEEKQKAAELLFKEYADGRFFPFADTNSFGSPSTVNSHKEKVIVDPNTGETKHRFAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00762862;
90% Identity: iTF_00963504;
80% Identity: -