Basic Information

Gene Symbol
-
Assembly
GCA_963576845.1
Location
OY756255.1:9877458-9881246[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.00014 0.021 16.2 5.1 2 23 238 260 238 260 0.96
2 11 0.00029 0.044 15.2 3.8 1 23 264 286 264 286 0.99
3 11 0.00086 0.13 13.7 0.5 2 23 293 315 292 315 0.93
4 11 4.2e-05 0.0063 17.8 4.6 1 23 322 345 322 345 0.96
5 11 4.9 7.4e+02 1.9 0.2 1 12 350 361 350 369 0.85
6 11 0.0014 0.21 13.0 2.3 1 23 380 403 380 403 0.97
7 11 0.31 46 5.7 0.2 5 21 415 431 414 432 0.90
8 11 3.7e-06 0.00055 21.2 0.2 1 23 439 461 439 461 0.97
9 11 3.2e-06 0.00047 21.4 2.9 1 23 465 487 465 487 0.98
10 11 1.1e-05 0.0016 19.7 2.0 1 23 493 515 493 515 0.99
11 11 3.3e-06 0.0005 21.3 1.0 1 23 521 543 521 543 0.99

Sequence Information

Coding Sequence
ATGTTCTTTCGAGCCGAATTCGATCGCAGTTGGTTTTATTGTTTCGGATTACGTTACGATCATTTTACTTTAAGCAATTGTTACACCTTCGCGGTTGCATGGGCTCGCTGCGACGAGAGGAGGTCGAAAGCATCTCGCCAGGGTACGAAAGACCGGGTGCCAATCGAGAGAAAAACTGTTGCAGCTACCAGCGAAGATCGCTTTAGTACGTTGCTGATGAAAGTGGAAAGAGACTCCGAGGACGAAGAAGCCGAAGAGGAGGATCAGCTCGAAAGAGAAGTGGTAGCTCGCAAGGTGAACGAAGACTGGACAACGGACGCCGTGAAAACAGTTTTAGTGCCCGTTAGGGACCCAGTGACGCAGCAGATCAGGAACATGTTGGTACCTGTCGAAGTGAGGGACAAAACTGGGTTAAACATGATCAAAAGTGTACTGGTACCGTTTCAGAGCAGCGATGGTTCGGTGTCGTATGAGATCAGGAAGGTGACAGTGCCGATTACGATCGAGTCGAAGCTGCTGGAGAACGCTGACGACGTCAAAGAAACTGGAAAGGAGAGCCAGGAGGCAGATGCAAAAGAAGAGAAACAGGAAACAAGGGTCGAGGAGGTGAACGTAAAAGTGGAGCAGTTTCTGGACGAGGAGGCTAAGTCAGACAGCCCAGGTAATGAATCGGAGGACAATTTCGAGGTGATGGACCAGACCCTGAGGAACAGTTGTCCGCTCTGTCAGAAGTGCTTTAAAGATGAGCACGAGATGCAGAAGCACGTCCGTCGGAGCCATCGGAAGCGCTACAGCTGTGACAAGTGCCAGAAGAGGTGTATGTCCGAGCAGGCCCTCGAGAAACACCAGAAGACCCACGTAGGTGCTTCGTTCTTGCAATGCTCCGTCTGTAATTTGAGGTATAAGACCAACGTAGGGCTGAAGAACCACTACGTCCGCGAGCACAGTAGTCTGGACCCGAAGTTCACCTGCGACTACTGCGGCAGGTGCTTTAAATTGAAGCACGACCTGAGCATCCACATCGACAGGACGCACATGAACCCGGAGTACATCTGCAGGTTCTGCGGGAGAGCCGTGAAGAACATACTGCACCACGAAGCGACGCACGAGGAGGAGGTGAATAAAGGCACCTCTCGGTACCGTTGCGATCACTGCCCTAAAGACTTCAAGCTGCTAAACAGACTGGCCAACCATTTGCTGAAGAAGCACAACGATCGCAGTCAGCCCAGCATGTTGAGAACATTGTGCGAAAAGAACTTCCAGTCGAAGAAGGACTTCTATCGACATGTTTTATCCGAGGATAGGATGAACAGATACAAGTGTGACACCTGCGGCAAGACTTATGCGAACGAACAGAATCTTCGCAGTCATGCGGCTGTGCACTCGCACACCTTTGTGTGTCATCTTTGTAGCAAGAACTTtgctaataattattctttgaaGTTGCATCTGAGGATGCATACTGGGGAACGACCTTATCAGTGCAAGGTCTGCTTGAAGACCTTCTCGAGGACCAACGCGCTTAGGGTGCACCAGTTCACGCACACCGGGGAGAGACCTTACGTTTGTGATCTTTGTGGACAGAGTTTCACGCAGCGGAGTAGCATGATGGGTCATCGACGCAAACATCCTGGAAATCATCCTCCGCCTCCACCTTTGTCGCTCAGCAAGCTGGAGCTGAACGAACATTTGACTTTGTGA
Protein Sequence
MFFRAEFDRSWFYCFGLRYDHFTLSNCYTFAVAWARCDERRSKASRQGTKDRVPIERKTVAATSEDRFSTLLMKVERDSEDEEAEEEDQLEREVVARKVNEDWTTDAVKTVLVPVRDPVTQQIRNMLVPVEVRDKTGLNMIKSVLVPFQSSDGSVSYEIRKVTVPITIESKLLENADDVKETGKESQEADAKEEKQETRVEEVNVKVEQFLDEEAKSDSPGNESEDNFEVMDQTLRNSCPLCQKCFKDEHEMQKHVRRSHRKRYSCDKCQKRCMSEQALEKHQKTHVGASFLQCSVCNLRYKTNVGLKNHYVREHSSLDPKFTCDYCGRCFKLKHDLSIHIDRTHMNPEYICRFCGRAVKNILHHEATHEEEVNKGTSRYRCDHCPKDFKLLNRLANHLLKKHNDRSQPSMLRTLCEKNFQSKKDFYRHVLSEDRMNRYKCDTCGKTYANEQNLRSHAAVHSHTFVCHLCSKNFANNYSLKLHLRMHTGERPYQCKVCLKTFSRTNALRVHQFTHTGERPYVCDLCGQSFTQRSSMMGHRRKHPGNHPPPPPLSLSKLELNEHLTL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00962000;
90% Identity
iTF_00963372;
80% Identity
-