Basic Information

Insect: Megachile lagopoda
Gene Symbol: -
Assembly: GCA_036983795.1
Location: CM072788.1:7375634-7377121[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00012 0.014 16.4 5.1 2 23 167 189 167 189 0.96

2 11 0.00025 0.029 15.4 3.8 1 23 193 215 193 215 0.99

3 11 0.00072 0.084 13.9 0.5 2 23 222 244 221 244 0.93

4 11 3.5e-05 0.0041 18.1 4.6 1 23 251 274 251 274 0.96

5 11 4.2 4.9e+02 2.1 0.2 1 12 279 290 279 298 0.85

6 11 0.0012 0.14 13.2 2.3 1 23 309 332 309 332 0.97

7 11 0.31 36 5.7 0.1 5 20 344 359 343 361 0.91

8 11 3.1e-06 0.00036 21.4 0.2 1 23 368 390 368 390 0.97

9 11 2.7e-06 0.00031 21.6 2.9 1 23 394 416 394 416 0.98

10 11 9.3e-06 0.0011 19.9 2.0 1 23 422 444 422 444 0.99

11 11 2.8e-06 0.00033 21.5 1.0 1 23 450 472 450 472 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00012	0.014	16.4	5.1	2	23	167	189	167	189	0.96
2	11	0.00025	0.029	15.4	3.8	1	23	193	215	193	215	0.99
3	11	0.00072	0.084	13.9	0.5	2	23	222	244	221	244	0.93
4	11	3.5e-05	0.0041	18.1	4.6	1	23	251	274	251	274	0.96
5	11	4.2	4.9e+02	2.1	0.2	1	12	279	290	279	298	0.85
6	11	0.0012	0.14	13.2	2.3	1	23	309	332	309	332	0.97
7	11	0.31	36	5.7	0.1	5	20	344	359	343	361	0.91
8	11	3.1e-06	0.00036	21.4	0.2	1	23	368	390	368	390	0.97
9	11	2.7e-06	0.00031	21.6	2.9	1	23	394	416	394	416	0.98
10	11	9.3e-06	0.0011	19.9	2.0	1	23	422	444	422	444	0.99
11	11	2.8e-06	0.00033	21.5	1.0	1	23	450	472	450	472	0.99

Sequence Information

Coding Sequence: ATGAAAGTGGAAAGAGACTCCGAGGACGAAGAAGCGGAAGAGGAAGATCAGCTCGAAAGAGAAGTGGTAGCTCGCAAGGTCAACGAAGACTGGACAACGGATGCTGTGAAAACTGTTTTAGTGCCCGTTAGGGACCCAGTGACGCAACAGATCAGGAACATGTTGGTACCTGTCGAAGTGAGGGACAAAACTGGGTTAAACATGATCAAAAGTGTACTGGTACCCTTTCAGAGCAGCGACGGTTCGGTCTCGTACGAGATCAGGAAGGTGACAGTACCGATCACGATCGAGTCGAAGCTGCTGGAGAACGCTGACGACCCCAAAGAAACCGGGAAAGAGGACAACAAGGAGACCGAtcgaaaagaagagaaacagGAAACAAGGACCGTTGAGGAGGTGAACGTGAAAGTGGAGCAGTTCCTGGACGAAGAGACCAAATCGAACGACAGCCCCGGATCCGAGGACAATTTCGAGGTGATGGATCAGACCCTGAGGAACAGTTGTCCGTTGTGTCAGAAGTGCTTCAAGGACGAACACGAGATGCAGAAGCACGTCCGTCGGAGCCACAGGAAGCGGTACAGCTGTGACAAGTGTCAGAAGAGGTGTATGTCCGAGCAGGCCCTCGAGAAACACCAGAAGACCCACGTGGGTGCTTCGTTTCTGCAGTGCTCCGTCTGCAACTTGAGGTACAAAACTAACGTGGGGCTGAAGAACCACTATGTCCGCGAGCACAGCAGTCTGGACCCGAAGTTCACCTGCGACTACTGCGGCAGGTGCTTCAAGTTGAAGCACGATCTGAGCATCCACATCGACAGGACCCACATGAACCCGGAGTACATCTGCAGGTTCTGCGGAAGAGCCGTGAAGAATATACTGCACCACGAAGCGACACACGAGGAGGAGGTCAACAAAGGCACCTCTCGGTACCGTTGCGATCACTGTCCTAAAGATTTCAAGCTGCTGAACAGACTGGCCAACCATTTGCTGAAGAAGCACAACGATCGCAGTCAGCCTAGCATGTTGAGAACGCTGTGCGAAAAGAATTTCCAGTCGAAAAAGGACTTCTATCGACATGTTCTAGCCGAGGATAGGATGAACAGATACAAATGTGACACCTGCGGCAAAACTTATGCGAACGAACAGAATCTTCGTAGTCATGCTGCTGTGCACTCGCACACCTTTGTGTGTCACCTTTGTAGCAAGAACTTTGCCAATAATTACTCCTTGAAGTTGCATCTTCGAATGCATACTGGGGAACGGCCTTATCAGTGCAAGGTCTGTTTGAAGACCTTCTCGAGGACCAACGCGCTTAGGGTGCACCAATTCACGCACACCGGGGAGAGACCGTACGTTTGTGATCTTTGTGGACAGAGTTTCACACAACGGAGTAGCATGATGGGTCATCGACGCAAACATCCTGGAAATCATCCGCCGCCTCCACCTTTGTCTCTCAGCAAGTTGGAACTCAACGAACATTTGACTTTGTGA
Protein Sequence: MKVERDSEDEEAEEEDQLEREVVARKVNEDWTTDAVKTVLVPVRDPVTQQIRNMLVPVEVRDKTGLNMIKSVLVPFQSSDGSVSYEIRKVTVPITIESKLLENADDPKETGKEDNKETDRKEEKQETRTVEEVNVKVEQFLDEETKSNDSPGSEDNFEVMDQTLRNSCPLCQKCFKDEHEMQKHVRRSHRKRYSCDKCQKRCMSEQALEKHQKTHVGASFLQCSVCNLRYKTNVGLKNHYVREHSSLDPKFTCDYCGRCFKLKHDLSIHIDRTHMNPEYICRFCGRAVKNILHHEATHEEEVNKGTSRYRCDHCPKDFKLLNRLANHLLKKHNDRSQPSMLRTLCEKNFQSKKDFYRHVLAEDRMNRYKCDTCGKTYANEQNLRSHAAVHSHTFVCHLCSKNFANNYSLKLHLRMHTGERPYQCKVCLKTFSRTNALRVHQFTHTGERPYVCDLCGQSFTQRSSMMGHRRKHPGNHPPPPPLSLSKLELNEHLTL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00964003; iTF_00962001; iTF_00963372; iTF_00962683;
90% Identity: iTF_00963372;
80% Identity: iTF_00962001;