Mlea020073.1
Basic Information
- Insect
- Megachile leachella
- Gene Symbol
- -
- Assembly
- GCA_963576845.1
- Location
- OY756255.1:9901826-9908702[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.00092 0.14 13.6 0.3 2 23 200 222 199 222 0.91 2 18 0.38 57 5.4 0.3 1 23 234 257 234 257 0.95 3 18 0.043 6.4 8.4 3.5 1 23 270 293 270 293 0.93 4 18 0.00015 0.023 16.1 5.8 1 23 299 321 299 322 0.95 5 18 0.0067 1 10.9 0.4 3 23 329 350 327 350 0.94 6 18 0.00076 0.11 13.9 1.5 1 23 355 378 355 378 0.98 7 18 3.4e-07 5.1e-05 24.4 0.4 2 23 385 406 384 406 0.96 8 18 2.9e-06 0.00043 21.5 1.3 1 23 412 434 412 434 0.97 9 18 3.7e-05 0.0056 18.0 1.0 1 23 440 462 440 462 0.98 10 18 0.038 5.7 8.5 5.2 2 23 559 580 558 580 0.97 11 18 8.3e-05 0.012 16.9 2.0 1 23 582 605 582 605 0.96 12 18 0.003 0.44 12.0 0.9 1 23 610 633 610 633 0.96 13 18 0.00013 0.019 16.3 2.2 1 23 639 662 639 662 0.96 14 18 0.0012 0.19 13.2 2.0 2 23 669 691 668 691 0.95 15 18 0.0081 1.2 10.6 0.3 1 23 696 718 696 718 0.96 16 18 0.00072 0.11 13.9 0.5 3 23 726 745 725 745 0.98 17 18 5.9e-06 0.00088 20.5 0.1 1 23 751 773 751 773 0.97 18 18 0.00056 0.084 14.3 0.4 1 23 779 801 779 801 0.97
Sequence Information
- Coding Sequence
- ATGAAGAAGTGGCAGATCTTGGAGTTCGACGGGAAACCTTACTACGCTTTTGTACCTGAAGGTGAAATACCGTTATACGAGGAGGATATCCCGGAACAAGTGGACGAGATAGATCACGAAGAGTGCAAGGACCTCGTGAAAGTGGAGTGCTTTTACGACGAGGACCTGCAGTACGACTCCACGGACGAGAAGTTGTACGAAGAAGAGCAACTGTTGGACCCGAGTGCCGAGCAAAGGGACGAGGAGGATGACGTGAAACCCATCATCCTGAACGGCACCATCGACGCTGACAACGACAAGGCGATCGGGGACCTGTACCAGGTCAAGGTCCACGGCAGCATGGTGACCATAGAGAAGCTGATGTCCAACGAGATGGACGAGAAGGTGGACCCAGTCGAGTTCCAACCCGAAGAGCAGGAGGAACAAGACGAAACGTACAACGACCAAGAACAACTCGAACAAGTCGACCAGGTGGACCAAGGTGACCAGGAAGAACAGGTAGAATACCTGGAAGAAGAGATCCTGGAGTCCATAAACAACCATTCCTCCCCGACCAAGACTCGCAGAAAGGTGTCAAAGAACGCGGGTGGCGCGTTGAAGTGCAAGGTCTGCTCCGAGATGTTCAGCTCTGCCATATCCTTCAGGAAGCACGTGGCGTGGACGCACAAGAAGAAGGTGTGCATCCAGGAGGACGGCGCGTACATATGCGCCGTCTGCGATTATAGGACCCTGAAGAAGAGTCTGTTCGCCGCGCACCTGGAGAGAAAACACGAGACCTGGTCCAGGAAGCGACCCAACAACATGTTGTTCCCGTGCGCAGCTTGCGGGTTCGTGTGTAGATCTAAGCATTCGCTGCAGTCGCACTTCATCAGGAAGCACACAGACCGGTACGAGCACCAATGCAAGTTCTGCCCGAAGAAGTTCAAGGTGAAGGGTGACTTGACTAACCACGTGCGGTTTCATCATAAAGAAAAGCCGATCAATTGCGACGTCTGCGGTAAACTGTGCCAGAACAGCGGCTCCCTTTACGTTCATCAGAAGTGGGCACATTATAAACCCAAGTACGAGTGTCACATATGTAAGCGACGTATGGTGACGCAGGAGAACCTGGACCAGCACCTGTTGACCCAGCACGAGAAGAGGGAGAAGATCGTGTGCGCAGAATGTGGAAAGACGTTCACGAAAAAGGACTCCTTCAAGAGGCACATGGCGGTGCACACGGGATGCAAACCACATTCCTGCCTCATCTGCAACAAACCCTTCGCCAGGAGGTCACAACTGCGTCAGCATTTGCTCATTCACACCGGCAAGAGACCCTTCGTGTGCGACATCTGCGGCAAAGCGTTCACACAGAAACCGGGACTCATCTGCCACAGGAAGACGCATCCTGGACCACATCCTCCGTTACCCGTCATGCCCATCGCGGATATCGTCAAGGAGTTCACCGAAGGATACGTGCAGGAAATTAACGCGAGAGAAAGCGAGGAGAGAATCGAGGAGGAGGCAATCCTGGATCCTCTGGAAGAGGAGTCCGACTCGCACATAACCATCGACTTCCCCGAAAGCTTAACCAGCTGGATCGATAAGGAGAACTTCGAGATCGAAAGCAACCTCGAAAGAGTGCAACCCGACTGCAGACTCTCCTGCGATCAACCAACTGAGAAAGTACCCTTAGAGTGCGACCACTGCCGTCACAAGTTCCTCAAAAAGAGCAACCTAGCCGAGCACCTGAAGAAGCATCGACACAGGTGTCCAGATTGTCCGAAGACCTTCAGACTCCGTCGATACCTGGCGTCCCACACGGAGAAGATGCACAGACGCCAGGTGTACGACTGCAGCGTGTGCGAGTACAAGAGCAACAATAAAGGCACCCTGAAGAACCACTACATACGGCTGCACACCAGCAGCTACAACTTCTCCTGCGACGTGTGtggaaaacaatttaaaataaagaaagcCTTGAACCACCACGTGAAGCAGAACCACAGCGACTCGCCGCCCATCGTTTGCGACGTGTGTGGACACTTCAGCAAGAACCTACACGCGCTGAAGGCACACATGAAGTACAGACATTACAAGCCGGAGTTCATCTGCAGGATCTGCAGGAGGGGTATGACGACTCAGGAGAACTTGGAGCAGCATTTAACATGGCACGAGACTAGGGAGAAGGTCCTGTGTCCCACATGTGGGAAGAGGTTTCGAGGACGAGACCTGGATTCACATATGAGGGTGCACACGGGGGTGAAACCGTTCCCGTGTCCCGTGTGCGGGAAATCCTTCAGGAGGCAGACCGCGCAGGAACAACACGTGCTGATTCATACGGGCAAGAGGCCGTACGTGTGCGACATATGTGGACAGGCTTTCGCGCAGAAACCTGGGCTTATTTGTCACAGGAAGAGACATCCTGGTCCTCTGCCGCCTCTTCCGGTTGTGTCCATCAAGAATATTGTTACGGAGTTCACGAAGGAGTATACTATGAAGAATATGATCAAGATCGAGTGA
- Protein Sequence
- MKKWQILEFDGKPYYAFVPEGEIPLYEEDIPEQVDEIDHEECKDLVKVECFYDEDLQYDSTDEKLYEEEQLLDPSAEQRDEEDDVKPIILNGTIDADNDKAIGDLYQVKVHGSMVTIEKLMSNEMDEKVDPVEFQPEEQEEQDETYNDQEQLEQVDQVDQGDQEEQVEYLEEEILESINNHSSPTKTRRKVSKNAGGALKCKVCSEMFSSAISFRKHVAWTHKKKVCIQEDGAYICAVCDYRTLKKSLFAAHLERKHETWSRKRPNNMLFPCAACGFVCRSKHSLQSHFIRKHTDRYEHQCKFCPKKFKVKGDLTNHVRFHHKEKPINCDVCGKLCQNSGSLYVHQKWAHYKPKYECHICKRRMVTQENLDQHLLTQHEKREKIVCAECGKTFTKKDSFKRHMAVHTGCKPHSCLICNKPFARRSQLRQHLLIHTGKRPFVCDICGKAFTQKPGLICHRKTHPGPHPPLPVMPIADIVKEFTEGYVQEINARESEERIEEEAILDPLEEESDSHITIDFPESLTSWIDKENFEIESNLERVQPDCRLSCDQPTEKVPLECDHCRHKFLKKSNLAEHLKKHRHRCPDCPKTFRLRRYLASHTEKMHRRQVYDCSVCEYKSNNKGTLKNHYIRLHTSSYNFSCDVCGKQFKIKKALNHHVKQNHSDSPPIVCDVCGHFSKNLHALKAHMKYRHYKPEFICRICRRGMTTQENLEQHLTWHETREKVLCPTCGKRFRGRDLDSHMRVHTGVKPFPCPVCGKSFRRQTAQEQHVLIHTGKRPYVCDICGQAFAQKPGLICHRKRHPGPLPPLPVVSIKNIVTEFTKEYTMKNMIKIE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01066410;
- 90% Identity
- iTF_00961973;
- 80% Identity
- -