Mlea013983.1
Basic Information
- Insect
- Megachile leachella
- Gene Symbol
- SCAND3
- Assembly
- GCA_963576845.1
- Location
- OY756252.1:46280-48698[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 1.5e-05 0.0023 19.2 3.0 2 23 278 299 277 299 0.97 2 15 0.018 2.7 9.5 4.1 1 23 305 328 305 328 0.96 3 15 2e-05 0.003 18.9 2.0 2 23 408 429 407 429 0.97 4 15 1.1e-05 0.0016 19.7 1.9 1 23 435 457 435 457 0.97 5 15 0.00012 0.018 16.4 0.4 1 23 463 485 463 485 0.94 6 15 2.6e-07 3.9e-05 24.8 0.9 1 23 500 522 500 522 0.98 7 15 4.9e-06 0.00073 20.8 0.5 1 23 528 550 528 550 0.97 8 15 8.5e-06 0.0013 20.0 2.3 1 23 556 578 556 578 0.98 9 15 0.00075 0.11 13.9 0.2 1 23 584 606 584 606 0.99 10 15 3.3e-06 0.0005 21.3 0.3 1 23 612 635 612 635 0.94 11 15 1.7e-05 0.0025 19.1 1.3 1 23 641 663 641 663 0.98 12 15 0.00037 0.056 14.9 4.7 1 23 669 691 669 691 0.98 13 15 5.6e-06 0.00083 20.6 0.2 1 23 697 720 697 720 0.96 14 15 3.7e-06 0.00055 21.2 0.6 1 23 726 748 726 748 0.96 15 15 3.3e-06 0.00049 21.3 4.5 1 23 754 776 754 776 0.99
Sequence Information
- Coding Sequence
- ATGTATTCGAATTACATCACCAACAAAAGATTATATCATCGAGGACAAATTGATGTAATGGATATGCCAGTACAATTCACttgtaattacaaatatttctttgtTTACGAGGATCAAATATCTAGATTTGTGGTACTAAAAGGTCTACATGGAAATACAGCAAGCGAAGTAGCCATGAAACTCTTGGATATATTAACTATTATTGGAGCACCGCAAGTGTTGCAGAGCAAAAATGGGCGTAATTTCGCGGAACAAGTTGTACAAGAGTTACGTTTATTATGGAAGGATTTTATAATACTTCACGGAGAAATTTCTGAAAGCGAAGAAAACAACagggattttaagaatttacttGAATGTTGGGTACAAGAAAATCCGACGAAAACATGGTACGAAGCTTTGAAACATGTACAAATTATTCAGAATTCAACGTTTCGTTGCGAAAATGGAAAGATTCCTTACGACATTTTATTTGGACGAAATGTACACGAAGAATTCCAAAAACAAATTAATACTATAGATCCGATAGAAGATATATGGGCAGAAGAAGAATGGGTTGATTTTACATTAGATTCGAAAGATGCGATCATTAAGGAAATAAAGGacggaaatgaaaatttaacagAGGATTCAAGCATGATGGATGCAAATAGTTCAAGAGAATTCGACGACGATCCCTACATCGATGATATCGACGAACCCCAAAGGGACACACTtggttttaattttgttaacgtCAGGAGCGAACCTTTAAATATACACACCGAAGATTTAATGTTTGAAGAGGAACCGATAATAGATGATAAAATAAAGCTAGAATCTCAAGATCTAAAGTGTACAGTTTGCCAAAAACAATATATGAAACCTGGTCATTTAAAGAATCATATGAGGACACATACGAAAGGAAAGATGTTTGAATGCAAACTCTGTAATAAAAAGTTTCATGtcataaatttatacaaaaagcaTGTAAGACAATCTCACACAGAAAATAAGTTACCAAGTTTGATTAGAACCAGAAGTAAAGATTTACAAGACGATTCAACTTTAGATGTAAAACCGGTTGAATACAAGTTTAatacagaattaattttaagcGATGCAGAATCTAACGTAACGGGCGAATTTACAAAAGTAACAAGAAATTCGAATCTTGTTAAAGAAAGGAAAAAGGTTCCTACAGAAACTCGTCCATTAAAAATGAACGGGGATCCAAATTTGCAATGTTCTTTCTGTAATcagaaattcaattttcctagTGTACTGAAAAGACATATGCGATCTCACACAAATGAACGGCCGTACATCTGTGATGTTTGTAATAAAAGCTTTAAACAATTGGGTCATCTTAGCCAACATTCGTTGACGCATAAGGATTATCGTTCATTTCTCTGCACCATTTGTGGAGTAAAATTCGAGACGTTGAGTTCATTAAAAATTCACTCTCAGTCGCACAAAGAAGCCTACATTTCAAAAACTAAGGACACTTTCCGATTATTTGAGTGTGATAATTGTAAGAAGGTGTTCACTACTAAAAGCGTATTAGAGCGACACATACTTACACATTCTCACGAACGTCAGTTTGCCTGCGTAGTTTGTGGGAAAAGATTCAAACAAGCAGGACACGTGAAATCTCATATGTTGGTGCATACAGGTGAACGAAAGTTCGAATGCACGGTATGCAAAAAAAGATTTAGTCTTTCCAATTCCCTTAAGAAACACATGTACGTGCACAACGGAGAAAAACCATATCAGTGCGACGTATGCGGTGCACGGTTCCTTGAAAAGAGAAATTTAAACGGACATCTGATGACTCATACGAACGAGCGTCCATTTCGCTGTAAAATTTGTGGGAAACGATATACTTTGGCAGATACTCTACGCCGTCATATAAGTGCAGCTCACGAGGATGGTCGCACGTACCAATGCGAAATTTGTgcaaaaatgtttaaacaaCTTGCACATTTGTCCGTTCACAAGAAAGTGCACAACGACGAGAGACCGTTCCAGTGTCATTTATGCGAGAAAAActttaaacataaaaatgtgcTCAAGTCTCATTTGGCTATTCATGCCAACGTAAGGCCATTCGAATGCGATGTATGTAAGGCTACGTTTGTCAGAAAGACAAATTTACAGACGCATATTGCATCTGCTCATATGAACGAAAGACCGTACGTTTGTACTATATGCGGAAAACGATTTAAGCAAATTAGTCATTTAAATGGTCACGTTGTAGTACACAGTAATTTAATGCCTTATCAATGTGATTTTTGTGATCGGCGATGTAACAGACTCGATAACTTGAAAAAGCACATGCGCCTCCATACGAAGAACAAAGAACAAATACTATAA
- Protein Sequence
- MYSNYITNKRLYHRGQIDVMDMPVQFTCNYKYFFVYEDQISRFVVLKGLHGNTASEVAMKLLDILTIIGAPQVLQSKNGRNFAEQVVQELRLLWKDFIILHGEISESEENNRDFKNLLECWVQENPTKTWYEALKHVQIIQNSTFRCENGKIPYDILFGRNVHEEFQKQINTIDPIEDIWAEEEWVDFTLDSKDAIIKEIKDGNENLTEDSSMMDANSSREFDDDPYIDDIDEPQRDTLGFNFVNVRSEPLNIHTEDLMFEEEPIIDDKIKLESQDLKCTVCQKQYMKPGHLKNHMRTHTKGKMFECKLCNKKFHVINLYKKHVRQSHTENKLPSLIRTRSKDLQDDSTLDVKPVEYKFNTELILSDAESNVTGEFTKVTRNSNLVKERKKVPTETRPLKMNGDPNLQCSFCNQKFNFPSVLKRHMRSHTNERPYICDVCNKSFKQLGHLSQHSLTHKDYRSFLCTICGVKFETLSSLKIHSQSHKEAYISKTKDTFRLFECDNCKKVFTTKSVLERHILTHSHERQFACVVCGKRFKQAGHVKSHMLVHTGERKFECTVCKKRFSLSNSLKKHMYVHNGEKPYQCDVCGARFLEKRNLNGHLMTHTNERPFRCKICGKRYTLADTLRRHISAAHEDGRTYQCEICAKMFKQLAHLSVHKKVHNDERPFQCHLCEKNFKHKNVLKSHLAIHANVRPFECDVCKATFVRKTNLQTHIASAHMNERPYVCTICGKRFKQISHLNGHVVVHSNLMPYQCDFCDRRCNRLDNLKKHMRLHTKNKEQIL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00963333;
- 90% Identity
- iTF_00963975; iTF_00963333; iTF_00964616; iTF_00961965;
- 80% Identity
- -