Mlag016466.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Megachile lagopoda
Gene Symbol
SCAND3
Assembly
GCA_036983795.1
Location
CM072796.1:111970-114391[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 1.5e-05 0.0018 19.2 3.0 2 23 278 299 277 299 0.97
2 15 0.018 2.1 9.5 4.1 1 23 305 328 305 328 0.96
3 15 2.3e-05 0.0026 18.7 1.6 2 23 409 430 408 430 0.97
4 15 1e-05 0.0012 19.7 1.9 1 23 436 458 436 458 0.97
5 15 0.0001 0.012 16.6 0.5 1 23 464 486 464 486 0.95
6 15 2.6e-07 3e-05 24.8 0.9 1 23 501 523 501 523 0.98
7 15 4.8e-06 0.00056 20.8 0.5 1 23 529 551 529 551 0.97
8 15 8.4e-06 0.00098 20.0 2.3 1 23 557 579 557 579 0.98
9 15 0.00075 0.087 13.9 0.2 1 23 585 607 585 607 0.99
10 15 3.3e-06 0.00038 21.3 0.3 1 23 613 636 613 636 0.94
11 15 1.7e-05 0.002 19.1 1.3 1 23 642 664 642 664 0.98
12 15 0.00037 0.043 14.9 4.7 1 23 670 692 670 692 0.98
13 15 5.5e-06 0.00064 20.6 0.2 1 23 698 721 698 721 0.96
14 15 3.7e-06 0.00043 21.2 0.6 1 23 727 749 727 749 0.96
15 15 3.3e-06 0.00038 21.3 4.5 1 23 755 777 755 777 0.99

Sequence Information

Coding Sequence
atgtattcgaATTACATCACCAACAAAAGATTATATCATCGAGGACAAATTGATGTAATGGACATGCCAGTACAATTCGcttgtaattacaaatatttctttgtttacGAGGATCAAATATCTAGGTTTGTGGTACTAAAAGGTCTGCATGGAAATACAGCAAGCGAAGTAGCTATGAAACTCTTGGatatattaactattattGGAGCGCCGCAAGTGTTACAGAGTAAAAATGGGCGCAATTTCGCAGAGCAAGTTGTACAAGAGTTACGTTTATTGTGGAAggattttataatacttcacggagaaatttctgaaagtgAAGAAAACAACagagattttaagaatttacttGAATGTTGGGTAGAAGAAAATCCGACAAAGACATGGTACGAAGCTTTGAAACATGTACAAATTATCCAGAATTCGACGTTTCGTtgtgaaaatggaaaaattccTTACGACATTTTATTTGGACGTAATGTACACGAAGAATTccaaaaacaaattaatactaTCGATCCAATAGAAGATATATGGGCAGAAGAAGAATGGGTTGATTTTACATTTGATTCGAAAGATGAGATCATTAAGGAAATAAAGgatggaaatgaaaatttaactgaGGATTCAAGCATGATGGATGCAAATAGTTCAAGGGAATTCGACGACGACCCCTATATCGATGATATCGACGAACCCCAGACGGACACACTtggttttaattttgttaacgtCAGGAGCGAACCTTTAAATATACACACCGAAGATTTAATGTTTGAGGAGGAACCGATAATGGTTGATAAGATAAAGCTAGAACCTCTAGATCTAAAGTGTACAGTTTGCCAAAAACAATATATGAAGCCTGGTCATTTAAAGAATCATATGAGAACACATACGAAAGGAAAGATGTTTGAATGCAAACTCTgtaataaaaagtttcatgtcataaatttgtacaaaaagcATGTAAGGCAATCTCATACAGAAAATAAGTTACCAAGTTTGATTAGAACCAGAAGAAGTAAGGATTTACAAGACGATTCAACATTAGATGTAAAACCGTTTGAATTAAACTGTTCttcagaattaaatttaagcgATACAGAATCTAACGTAACGGACGAATCTCCAAAAGCAACAAAAAATTCGAATCTTGctaaagaaaggaaaaaggtTCCTACAGAAAGTCGTCCGTTAAAAATGAATGGGGATCCAAATCTGGAATGTTCGTTCTGTAatcagaaattcaattttcctagTGTACTGAAAAGACATATGCGATCTCACACAAACGAAAGGCCGTACATCTGTGACGTTTGTAATAAAAGCTTTAAACAACTGGGTCATCTTAGCCAACATTCGTTAACGCACAAGGATTATCGTTCGTTTCTCTGCACCATTTGTGGTGTAAAATTCGATACGTTGAGTTCATTAAAAGTTCACTCTCAGTCACACAAAGAAGCCTACATTTCAAAAGCTAAGGAGACTTTTCGATTATTCGAGTGCGATAATTGTAAAAAGGTGTTCACTACTAAAAGCGTATTAGAGCGACACATACTTACACATTCTCACGAACGTCAGTTTGCCTGCGTAGTTTGTGGGAAAAGATTCAAACAAGCAGGACACGTGAAATCTCATATGTTGGTGCATACAGGTGAACGAAAGTTCGAATGCACGGTATGCAAAAAGAGATTTAGTCTTTCCAATTCCCTTAAGAAACACATGTACGTGCATAACGGAGAAAAACCGTATCAGTGCGACGTATGCGGCGCACGGTTccttgaaaagagaaatttaaaCGGACATCTTATGACTCATACGAACGAGCGTCCATTTCGCTGTAAAATTTGTGGGAAACGGTATACTTTGGCAGATACTCTGCGCCGTCATATAAGTGCAGCTCACGAGGACGGTCGCACGTACCAATGCGAAATTTGtgcaaaaatgtttaaacagcTTGCACACTTGTCCGTTCACAAGAAAGTGCATAACGACGAGAGACCGTTCCAGTGTCATTTATGCGAGAAAAactttaaacataaaaatgtgcTCAAGTCTCATTTGGCTATTCATGCCAATGTAAGGCCATTCGAATGCGATGTATGTAAGGCTACGTTTGTCAGAAAGACAAATTTACAGACGCATATTGCATCGGCTCACATGAACGAAAGACCGTACGTTTGTACTATATGCGGAAAACGATTTAAGCAAATTAGTCATTTAAATGGTCACGTCGTAGTACACAGTAATTTAATGCCTTATCAATGTGATTTTTGTGATCGGCGATGTAACAGACTCGATAACTTGAAAAAGCATATGCGTCTCCATACGAAGAACAAAGAACAAATACTATAA
Protein Sequence
MYSNYITNKRLYHRGQIDVMDMPVQFACNYKYFFVYEDQISRFVVLKGLHGNTASEVAMKLLDILTIIGAPQVLQSKNGRNFAEQVVQELRLLWKDFIILHGEISESEENNRDFKNLLECWVEENPTKTWYEALKHVQIIQNSTFRCENGKIPYDILFGRNVHEEFQKQINTIDPIEDIWAEEEWVDFTFDSKDEIIKEIKDGNENLTEDSSMMDANSSREFDDDPYIDDIDEPQTDTLGFNFVNVRSEPLNIHTEDLMFEEEPIMVDKIKLEPLDLKCTVCQKQYMKPGHLKNHMRTHTKGKMFECKLCNKKFHVINLYKKHVRQSHTENKLPSLIRTRRSKDLQDDSTLDVKPFELNCSSELNLSDTESNVTDESPKATKNSNLAKERKKVPTESRPLKMNGDPNLECSFCNQKFNFPSVLKRHMRSHTNERPYICDVCNKSFKQLGHLSQHSLTHKDYRSFLCTICGVKFDTLSSLKVHSQSHKEAYISKAKETFRLFECDNCKKVFTTKSVLERHILTHSHERQFACVVCGKRFKQAGHVKSHMLVHTGERKFECTVCKKRFSLSNSLKKHMYVHNGEKPYQCDVCGARFLEKRNLNGHLMTHTNERPFRCKICGKRYTLADTLRRHISAAHEDGRTYQCEICAKMFKQLAHLSVHKKVHNDERPFQCHLCEKNFKHKNVLKSHLAIHANVRPFECDVCKATFVRKTNLQTHIASAHMNERPYVCTICGKRFKQISHLNGHVVVHSNLMPYQCDFCDRRCNRLDNLKKHMRLHTKNKEQIL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00963333;
90% Identity
iTF_00962648;
80% Identity
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