Mlea020070.1
Basic Information
- Insect
- Megachile leachella
- Gene Symbol
- -
- Assembly
- GCA_963576845.1
- Location
- OY756255.1:9888515-9893978[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 22 0.00013 0.02 16.3 1.4 1 23 97 120 97 120 0.96 2 22 4.2e-05 0.0063 17.8 5.2 1 23 126 148 126 148 0.98 3 22 0.015 2.2 9.8 7.6 1 23 157 180 157 180 0.94 4 22 0.0033 0.49 11.9 1.2 1 23 186 208 186 208 0.91 5 22 2.7e-05 0.004 18.4 2.4 1 23 213 236 213 236 0.96 6 22 0.0014 0.21 13.0 0.9 1 23 242 264 242 264 0.98 7 22 6e-07 9e-05 23.6 0.8 1 23 268 290 268 290 0.98 8 22 0.00088 0.13 13.7 7.4 1 23 296 318 296 318 0.99 9 22 6.4e-05 0.0095 17.3 3.2 1 23 324 346 324 346 0.97 10 22 4.1e-05 0.0062 17.9 1.4 1 23 456 478 456 478 0.97 11 22 3.6 5.4e+02 2.3 6.7 1 23 514 537 514 537 0.94 12 22 0.012 1.7 10.2 0.9 3 23 542 562 540 562 0.92 13 22 0.057 8.6 8.0 0.4 1 23 570 593 570 593 0.90 14 22 0.12 18 6.9 7.6 3 23 657 677 656 677 0.97 15 22 0.014 2.1 9.9 4.1 1 23 685 708 685 708 0.97 16 22 0.056 8.4 8.0 1.3 1 23 723 746 723 746 0.95 17 22 6.5e-07 9.7e-05 23.5 0.8 1 23 752 775 752 775 0.96 18 22 0.00031 0.047 15.1 0.8 2 23 781 803 780 803 0.94 19 22 0.0017 0.25 12.8 1.6 1 23 808 831 808 831 0.97 20 22 4.1e-08 6.2e-06 27.3 0.6 2 23 838 859 837 859 0.97 21 22 1.7e-05 0.0025 19.1 0.8 1 23 865 887 865 887 0.98 22 22 6.6e-07 9.9e-05 23.5 0.1 1 23 893 915 893 915 0.98
Sequence Information
- Coding Sequence
- ATGGATCTCCTGGTGATTCGAGACTTTTTGAGATCGCCGCTCATAAATCAGAAGCTCGGTAAAGAAGATTCGAAAGCACGCAAACCAGCCTTCCTCCAGAGAAGACTCTTACGAGTTTCGAAAATTCGCAGACGTAACAGACACTACGAAACAAAAGAAGAAAGTGTTCAACATGAAGAAGAGAAGTCTTCGATCCGTTCAACCAGTAAGAAACCTAACGATTGTTCAGCTAAATTACAGAGCAATCCACAGCAGGAAGATCTGTACAAAAAGCTCCACGACGGCACGTACACCTGCGACATTTGTCAAACAACGTTCGAACAGAAGAGCAAGATCCTCCGACACATCACCAGCAAGCACAGTTTCCACCGACCGTTCAAGTGCCAGACCTGCGACAAGACGTTCAAGTACAAATGCGACCTGAAAGCCCACAAGCTGGTGCACCAGGAGGTCGACTCGAGTTTGCTGCACTGCTGCGACAAATGCGACTATCGAACGAAGACGAAGAACAACCTGAAGTCACACTACATCAGAAGACACACGGACGACTACAAGTTCGCCTGCGAGCACTGTGGCAAGCGTTTCAAGATGGAGTGGGACTTGAAGTTCCACGTTGGCACCCACAGCAACTCCCAGCACATGTGCGACGTTTGCGGAAAATTTTATACCAGCAATTACTCGCTGTATAAGCACAGGAAGGTGGCACATTTGAACGAGTACAAGTTTCAATGCAGCGTTTGCAATAAGAGGCTACTCACGCAGGAGAACCTGGACAACCACATGCAGCAGCACAGCAGAACGTACGAGTGCAAGGATTGTGGCAAGGTGTTCGCCTCGAAGAGATACCTGGCGACACACACGACTACACACACTGGGGTCAAACCGTATACTTGTCATATTTGTAAGAAGAACTTCAGAACGTCGCATATGAGAAATACGCATCTGCTCACGCACTCGGCGGAGAGGCCACATATCTGTGATCTTTGTGGACAGTCGTTTAAACGGAGGTATTATATGATAGAGCATCGGAGGAAACATCCTGATGCTCACCTGTCCTCGCCACCGGTGCCTCTGGGGAAGAAGAGAAATGCTGAATTGGATGGACAGATTGTGACTGAATTTCGGGCGGAGATTTCTTTGGATCCTGTCAGCTGCAAGAAGATGACCATCGGAACTTCCGGTCAACTTACAGAAGACTCCGTCCCGACGCAGGTCCACACAGTGAAACTCGAAGAGAGCTCCGAAACGACTATTTTCTTAAAGATGGAGGAAGTGCCACGTAAAGACGTTCCGAAAACGAATTGCGAGACGAGTTCTTACGTTTCGGGTTCTCTGATACACCTCTGCGAAGTGAGCATCGATTACTACACGTGCAACAAGTGTGGGATCAAGTTCCCTACCGAGAGCATGCTGAGCAAACACAAAATGTTCCACAAACTGCACTCGTGGCTTCGCAAGAAACGTCTGCGTGCGAAGAACCAGCTAAAATCGGGAAAACTAATCAAACAGAAGTCTTTGAAAAACCCAGAAAAGATGAAGTACGTCTGCATGTGCTGCAGCTTCAGCTGCAACAGAAAGTCCACCATCACCATCCACATGAAGAAGAAACATTTAGAGATCTCGTGCATAATCTGCGACCTGAAATGTAACGATTACTCCACGTTGGCGAAGCACATGGAGAAACACAGGAACGCGAAGACGAAATACTTCAAGTGCAACGTGTGTAGCTTTGTCAGCAAGAAGAGGGGTGCTTTGGTGTCCCACGTGGTTCAGACGCACCGGAAGACTgacgagaagaagaagaggacgcAGATGAAGCGCGACGTCAAATCTGAGGTGAAGAAAAGCCCGGAAGAAGCAAAGGATCCTCTGATCGACTCGTGTACCTCGTCAGAGTTCGACTGCAAGGACGAGGTGATATCGGAACCAGAGGACGACAAGAACTTCGACAAGGATCCTGTGGAACACTGCGACTTGTGCGACTTCACGTGTTCGAAGAGGAGCACCCTGTACTCGCACAAACGCAGGCACAAGGTGGACGTAGCTGAGGTGTACTTCTGCAACGAGTGTCCGTTCAAGACCAATAAGAAGTCATCCCTATATTCGCACAGGAAGAGGAAGCACAGACCACCTAAGCCTCTCACGGAAGATGGCCAGCCACAGTTGTTCTACTGCGCCCAGTGCGACTACAAGAACAAGAACAAGTACGAGCTGAGGGTGCACGTGGCCAGGAAGCACACCAATGACTTCAAGTTCTCCTGCGAGATCTGCGGCAAGAAGTTCAAGGTGAAAGGCGACCTGACCAACCACATACGCTTCAGCCACAAGGAACAGCCCGTCATGTGCGACGTCTGCGGTAAAACCTGTCCAAACAGTAACTCGTTGTACGTGCATCAGAAGTTCGCTCACTACAAGGCCCAGTACGAGTGCCATTTGTGCAAGAGGCGAATGGTCACCCAGGAGAACCTGAACGAGCATCTGATCAAGCAGCACGAGAACAGGAAGGCCGTGATGTGCGAGGAGTGCGGGAAGACCTTCTCCAGGAACAGCAGGCTGAAGGTGCACATGAGAGTCCACACCGGAGATAAACCGTACAATTGCACGATCTGCAGCAAGTCGTTCGCTCGGAGGACGGCCATGAAGCAGCATCTGCTGATACACACCGGAGTTAGGCCGTACGTCTGCGATATATGTGGGAAGGCGTTCACACAGAAGCCTGGCTTGATCAGCCACAGGAAGTCGCATCCTGGATCGCATCCGCCGCTTCCGAGAATCTTCATCGACCACATACTGCAGGACGTTATGAACAAATGA
- Protein Sequence
- MDLLVIRDFLRSPLINQKLGKEDSKARKPAFLQRRLLRVSKIRRRNRHYETKEESVQHEEEKSSIRSTSKKPNDCSAKLQSNPQQEDLYKKLHDGTYTCDICQTTFEQKSKILRHITSKHSFHRPFKCQTCDKTFKYKCDLKAHKLVHQEVDSSLLHCCDKCDYRTKTKNNLKSHYIRRHTDDYKFACEHCGKRFKMEWDLKFHVGTHSNSQHMCDVCGKFYTSNYSLYKHRKVAHLNEYKFQCSVCNKRLLTQENLDNHMQQHSRTYECKDCGKVFASKRYLATHTTTHTGVKPYTCHICKKNFRTSHMRNTHLLTHSAERPHICDLCGQSFKRRYYMIEHRRKHPDAHLSSPPVPLGKKRNAELDGQIVTEFRAEISLDPVSCKKMTIGTSGQLTEDSVPTQVHTVKLEESSETTIFLKMEEVPRKDVPKTNCETSSYVSGSLIHLCEVSIDYYTCNKCGIKFPTESMLSKHKMFHKLHSWLRKKRLRAKNQLKSGKLIKQKSLKNPEKMKYVCMCCSFSCNRKSTITIHMKKKHLEISCIICDLKCNDYSTLAKHMEKHRNAKTKYFKCNVCSFVSKKRGALVSHVVQTHRKTDEKKKRTQMKRDVKSEVKKSPEEAKDPLIDSCTSSEFDCKDEVISEPEDDKNFDKDPVEHCDLCDFTCSKRSTLYSHKRRHKVDVAEVYFCNECPFKTNKKSSLYSHRKRKHRPPKPLTEDGQPQLFYCAQCDYKNKNKYELRVHVARKHTNDFKFSCEICGKKFKVKGDLTNHIRFSHKEQPVMCDVCGKTCPNSNSLYVHQKFAHYKAQYECHLCKRRMVTQENLNEHLIKQHENRKAVMCEECGKTFSRNSRLKVHMRVHTGDKPYNCTICSKSFARRTAMKQHLLIHTGVRPYVCDICGKAFTQKPGLISHRKSHPGSHPPLPRIFIDHILQDVMNK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00961967; iTF_00963335;
- 90% Identity
- iTF_00961967; iTF_00963335;
- 80% Identity
- -