Mlig006391.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Megachile ligniseca
Gene Symbol
-
Assembly
GCA_945859565.1
Location
CAMAOB010000037.1:928904-936137[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 0.00014 0.015 16.1 1.4 1 23 213 236 213 236 0.96
2 22 4.5e-05 0.0047 17.7 5.2 1 23 242 264 242 264 0.98
3 22 0.016 1.7 9.6 7.6 1 23 273 296 273 296 0.94
4 22 0.0036 0.37 11.7 1.2 1 23 302 324 302 324 0.91
5 22 2.9e-05 0.003 18.3 2.4 1 23 329 352 329 352 0.96
6 22 0.0016 0.16 12.8 0.9 1 23 358 380 358 380 0.98
7 22 6.5e-07 6.7e-05 23.4 0.8 1 23 384 406 384 406 0.98
8 22 0.00096 0.098 13.5 7.4 1 23 412 434 412 434 0.99
9 22 6.9e-05 0.0071 17.1 3.2 1 23 440 462 440 462 0.97
10 22 0.0015 0.16 12.8 2.8 2 23 578 599 577 599 0.94
11 22 3.9 4e+02 2.1 6.7 1 23 637 660 637 660 0.94
12 22 0.013 1.3 10.0 0.9 3 23 665 685 663 685 0.92
13 22 0.062 6.4 7.8 0.4 1 23 693 716 693 716 0.90
14 22 0.13 13 6.8 7.6 3 23 780 800 779 800 0.97
15 22 0.015 1.5 9.7 4.1 1 23 808 831 808 831 0.97
16 22 0.061 6.3 7.8 1.3 1 23 846 869 846 869 0.95
17 22 7e-07 7.2e-05 23.4 0.8 1 23 875 898 875 898 0.96
18 22 0.00034 0.035 14.9 0.8 2 23 904 926 903 926 0.94
19 22 0.0018 0.19 12.6 1.6 1 23 931 954 931 954 0.97
20 22 4.4e-08 4.6e-06 27.1 0.6 2 23 961 982 960 982 0.97
21 22 1.8e-05 0.0019 18.9 0.8 1 23 988 1010 988 1010 0.98
22 22 7.1e-07 7.3e-05 23.3 0.1 1 23 1016 1038 1016 1038 0.98

Sequence Information

Coding Sequence
ATGCCAAGTTCTCCAAAAAAGGTTCGCCTTTTTCGAGCGAAACACACGCCAGTGCATGCTCGTGTGTGGTACAATGCGCTAGACCCCCTCGCTCCAACTTTTCTGATAGTAAAACTAGAGGACAATTACTTTCGGATACCAACGTCGCTGAGCATGTTCATGATGAAGGAACCACCACCCAGCGGAGAAGCGGTCGCTCAGGCTCCGAAATCAGTCCCGAAGACCAGTCGGACCGAAGAGAGGCCGAGAGCCAACTCTGTGAGGATCGACGAGTCGTCGGACGAACTGGAGGACGTGCCGTTGGACTTCCGGAAGAAGTTACAGGACGAAAAGCACATGAAATCGCTGCAGCTCATAAATCCGAAGCACAAACTCGGTAGCCAAGAAGATTCAAAACGCAAACCAGCCTCCCTTCTCCAGAGAAGAAGACTCTTACGAGTTTCGAAAATCCGCAGACGTAACAGACATTCCTACGAAACAAAAGATGGAAGTGTTCAACGAGAAGAAGCAAACAAAAAGTCTTCAATCCGACGTTCGACCAGCAGGAAGCTACCCGATTCTAACGATTGTTCAGCTAAATTACAGAGCAACCCAACACAGCAGGAAGATCTGTACAAAAAGCTTCACGACGGTACATacacctgcgacatttgtcagacgacgttcgagcagaagagcaagatcctccgtcacatcaccagcaagcacagtttccatcgaccgttcaaatgccagacctgcgacaagacgttcaagtataaatgcgacctgaaggctcacaagctggtccaccaggaagtcgactctagtttgctgcactgctgcgataaatgcgactatcggacgaagacgaagaacaacctgaagtcccactacatcagaaggcacacggacgactacaagttcgcctgcgagcactgcggcaagcgtttcaagatggagtgggacttgaagttccacgtcggcacccacagcaactcccagcacatgtgcgacgtttgcgggaaattttatacgagcaactactcgctgtacaagcataggaaggtggctcatttaaacgagtacaagtttcagtgcagcgtttgcaataaaaggctactcacgcaggagaatctggacaaccacatgcaacagcacagcagaacgtacgagtgcaaggattgtggcaaagtgttcgcctcgaagaggtacctggcgacacacacgactacccacacaggggtcaaaccgtacacttgtcatatttgtaagaagaacttcagaacgtcgcatatgaggaacacgcatctgctgacgcactctgcggagagaccacatatctgtgatctttgtggacagtcttttaagaggaggtattatatgatagagcatcgaaggaaacatcctgatgctcacctgtcgTCGCCACCGGTGCCTCTTGGGAAGAAGAGGAACGTTGCTGAGTTGGATGGGCAGATTGTGACTGAATTTCGAGCGGAGATTTCTTTGGATCGTGTTAGCTGCAAGAAGATGACCATCGGAACTTCCGGTCAACTTAGAGAAGACTCCGTCCCGACGCAGCAGGTCCACACCACGAAATCCAAAGAGAGCTCCGAAGCGCCAATGACTATTTTCTTAAAGATGGACGACGAAGAGCGACGTAAAGACGTTCAGAAAACAAATTGCGAGACCAGTTCTTACGTTTCGGGTTCTCTGATACATCTCTGCGAAGTGAGCATCGATTACTGTACGTGCGACAAGTGTGGGATCAAGTTCCCCACCGAGAACATGCTGAACAAACACAAAATGTTCCACAAACTGCACTCGTGGATTCGCAAGAAGCGTCTGCGTGCGAAGAATCAGCTAAAATCTTCGGGAACACTAATCAAACAAACGAAGTCTCTGAAAATCCCAGAAAAGATGAAGTATGTCTGCATGTGCTGCAGCTTCAGCTGCAACAGGAAGTCCACCATCACCATCCACATGAAGAAGAAACATTTAGAGATCTCGTGCATAATCTGCGACCTGAAATGCAACGATTACTCCACGTTGGCGAAGCACATGGAGAAACACAGAAACACGAAGACAAAATACTTCAAGTGCAACGTATGCAGCTTCGTTAGCAAGAAGAGGGGTGCTCTGGTGTCCCACGTGGTCCAAACGCATCGGAAGATTGATGACAAGAAGAAGAGGACGCCGACGAAGCGCGATGTCAAATCCAAGGAGAAGAAAAGTCCGGAAGAAGCAAAGGATCCGTTAATTGACTCGTGCACCTCGTCAGAGTTCGACTGCAAGGACGAGGTGATATCAGAACCCGAGGACGATAAGAACTTCGACAAGGATCCTGTGGAACACTGCGACTTGTGTGACTTCACGTGTTCGAAGAGGAGCACTTTGTATTCGCATAAACGCAGGCACAAGGTGGACGTAGCCGAGGTGTATTTCTGCAACGAGTGTCCCTTCAAGACCAACAAGAAGTCGTCCCTGTATTCGCACAGGAAGAGGAAGCACAGACCACCTAAACCTCTCACGGAAGATGGCCAGCCACAGTTGTTCTACTgcgcccagtgcgactacaagaacaagaacaagtacgagctgagggtgcacgtggccaggaagcacaccaacgacttcaagttctcctgcgagatctgcggcaagaagttcaaggtgaaaggcgacctgaccaaccacatacgcttcagccacaaggaacagcccgtcatgtgcgacgtctgcggtaaaacctgtccaaacagtaattcgttgtacgtgcatcagaagttcgctcattacaaggcccagtacgagtgccatttgtgcaagaggcgaatggtcacccaggagaacctgaacgagcatctgatcaagcagcacgagaacaggaaggccgtgatgtgcgaggagtgcgggaagaccttctccaggaacagcaggctgaaggtgcacatgagagtccacaccggcgataaaccgtacaattgcacgatctgcagcaagtcgttcgctcggagaacggccatgaagcagcatctgctgatacacaccggggttaggccgtacgtttgcgacatatgcgggaaggcgttcacacagaagcctggcttgatcagccacaggaagtcgcatcctggatcgcatccgccgcttcCGAGAATCTTTATCGATCACATATTGCAGGACGTTATGAACAAATGA
Protein Sequence
MPSSPKKVRLFRAKHTPVHARVWYNALDPLAPTFLIVKLEDNYFRIPTSLSMFMMKEPPPSGEAVAQAPKSVPKTSRTEERPRANSVRIDESSDELEDVPLDFRKKLQDEKHMKSLQLINPKHKLGSQEDSKRKPASLLQRRRLLRVSKIRRRNRHSYETKDGSVQREEANKKSSIRRSTSRKLPDSNDCSAKLQSNPTQQEDLYKKLHDGTYTCDICQTTFEQKSKILRHITSKHSFHRPFKCQTCDKTFKYKCDLKAHKLVHQEVDSSLLHCCDKCDYRTKTKNNLKSHYIRRHTDDYKFACEHCGKRFKMEWDLKFHVGTHSNSQHMCDVCGKFYTSNYSLYKHRKVAHLNEYKFQCSVCNKRLLTQENLDNHMQQHSRTYECKDCGKVFASKRYLATHTTTHTGVKPYTCHICKKNFRTSHMRNTHLLTHSAERPHICDLCGQSFKRRYYMIEHRRKHPDAHLSSPPVPLGKKRNVAELDGQIVTEFRAEISLDRVSCKKMTIGTSGQLREDSVPTQQVHTTKSKESSEAPMTIFLKMDDEERRKDVQKTNCETSSYVSGSLIHLCEVSIDYCTCDKCGIKFPTENMLNKHKMFHKLHSWIRKKRLRAKNQLKSSGTLIKQTKSLKIPEKMKYVCMCCSFSCNRKSTITIHMKKKHLEISCIICDLKCNDYSTLAKHMEKHRNTKTKYFKCNVCSFVSKKRGALVSHVVQTHRKIDDKKKRTPTKRDVKSKEKKSPEEAKDPLIDSCTSSEFDCKDEVISEPEDDKNFDKDPVEHCDLCDFTCSKRSTLYSHKRRHKVDVAEVYFCNECPFKTNKKSSLYSHRKRKHRPPKPLTEDGQPQLFYCAQCDYKNKNKYELRVHVARKHTNDFKFSCEICGKKFKVKGDLTNHIRFSHKEQPVMCDVCGKTCPNSNSLYVHQKFAHYKAQYECHLCKRRMVTQENLNEHLIKQHENRKAVMCEECGKTFSRNSRLKVHMRVHTGDKPYNCTICSKSFARRTAMKQHLLIHTGVRPYVCDICGKAFTQKPGLISHRKSHPGSHPPLPRIFIDHILQDVMNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00962647;
90% Identity
iTF_00962647;
80% Identity
-