Basic Information

Insect: Megachile lagopoda
Gene Symbol: -
Assembly: GCA_036983795.1
Location: CM072788.1:7385079-7390886[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 0.00013 0.015 16.2 1.4 1 23 109 132 109 132 0.96

2 22 4.2e-05 0.0049 17.8 5.2 1 23 138 160 138 160 0.98

3 22 0.015 1.7 9.8 7.6 1 23 169 192 169 192 0.94

4 22 0.0033 0.39 11.8 1.2 1 23 198 220 198 220 0.91

5 22 2.7e-05 0.0032 18.4 2.4 1 23 225 248 225 248 0.96

6 22 0.0015 0.17 13.0 0.9 1 23 254 276 254 276 0.98

7 22 6.1e-07 7.1e-05 23.6 0.8 1 23 280 302 280 302 0.98

8 22 0.0009 0.1 13.6 7.4 1 23 308 330 308 330 0.99

9 22 6.5e-05 0.0075 17.2 3.2 1 23 336 358 336 358 0.97

10 22 0.0014 0.17 13.0 2.8 2 23 474 495 473 495 0.94

11 22 4.4 5.2e+02 2.0 6.9 1 23 533 556 533 556 0.94

12 22 0.012 1.4 10.1 0.9 3 23 561 581 559 581 0.92

13 22 0.058 6.7 7.9 0.4 1 23 589 612 589 612 0.90

14 22 0.12 14 6.9 7.6 3 23 676 696 675 696 0.97

15 22 0.014 1.6 9.9 4.1 1 23 704 727 704 727 0.97

16 22 0.057 6.6 8.0 1.3 1 23 742 765 742 765 0.95

17 22 6.6e-07 7.6e-05 23.5 0.8 1 23 771 794 771 794 0.96

18 22 0.00032 0.037 15.1 0.8 2 23 800 822 799 822 0.94

19 22 0.0017 0.2 12.8 1.6 1 23 827 850 827 850 0.97

20 22 4.2e-08 4.8e-06 27.3 0.6 2 23 857 878 856 878 0.97

21 22 1.7e-05 0.002 19.0 0.8 1 23 884 906 884 906 0.98

22 22 6.7e-07 7.7e-05 23.5 0.1 1 23 912 934 912 934 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	0.00013	0.015	16.2	1.4	1	23	109	132	109	132	0.96
2	22	4.2e-05	0.0049	17.8	5.2	1	23	138	160	138	160	0.98
3	22	0.015	1.7	9.8	7.6	1	23	169	192	169	192	0.94
4	22	0.0033	0.39	11.8	1.2	1	23	198	220	198	220	0.91
5	22	2.7e-05	0.0032	18.4	2.4	1	23	225	248	225	248	0.96
6	22	0.0015	0.17	13.0	0.9	1	23	254	276	254	276	0.98
7	22	6.1e-07	7.1e-05	23.6	0.8	1	23	280	302	280	302	0.98
8	22	0.0009	0.1	13.6	7.4	1	23	308	330	308	330	0.99
9	22	6.5e-05	0.0075	17.2	3.2	1	23	336	358	336	358	0.97
10	22	0.0014	0.17	13.0	2.8	2	23	474	495	473	495	0.94
11	22	4.4	5.2e+02	2.0	6.9	1	23	533	556	533	556	0.94
12	22	0.012	1.4	10.1	0.9	3	23	561	581	559	581	0.92
13	22	0.058	6.7	7.9	0.4	1	23	589	612	589	612	0.90
14	22	0.12	14	6.9	7.6	3	23	676	696	675	696	0.97
15	22	0.014	1.6	9.9	4.1	1	23	704	727	704	727	0.97
16	22	0.057	6.6	8.0	1.3	1	23	742	765	742	765	0.95
17	22	6.6e-07	7.6e-05	23.5	0.8	1	23	771	794	771	794	0.96
18	22	0.00032	0.037	15.1	0.8	2	23	800	822	799	822	0.94
19	22	0.0017	0.2	12.8	1.6	1	23	827	850	827	850	0.97
20	22	4.2e-08	4.8e-06	27.3	0.6	2	23	857	878	856	878	0.97
21	22	1.7e-05	0.002	19.0	0.8	1	23	884	906	884	906	0.98
22	22	6.7e-07	7.7e-05	23.5	0.1	1	23	912	934	912	934	0.98

Sequence Information

Coding Sequence: ATGAGGTCGATTGTGGAAGAGAAATCGCTGCAGCTCATAAATCAGAAGCACAAACTCGGTAGCCAAGAAGATTCAAAACGCAAACCAGCCTCCCTTCTGCAGAGAAGAAGACTCTTACGAGTTTCGAAAATCCGCAGACGTAACAGACGTTCCTACGAAACAAAAGATGGAAGTAATAGTGTTCAACGGGAAGAAGCAAACAAAAAGTCTTCGATCCGACGTTCGACCAGCAGGAAGCTACCCGATTCTAACGATTGTTCAGCTAAATTACAGAGCAAGCCAACTCAGCAGGAAGACCTGTACAAAAAGCTTCACGACGGTACGTACACCTGCGACATTTGCCAGACGACGTTCGAGCAGAAGAGCAAGATCCTCCGTCACATCACCAGCAAGCACAGTTTCCATCGACCGTTTAAATGCCAGACCTGTGACAAAACGTTCAAGTACAAATGCGACCTGAAGGCTCACAAGCTGGTCCACCAGGAGGTCGACTCGAGTTTGCTGCACTGCTGCGATAAATGCGACTATCGGACGAAAACGAAGAACAACCTGAAGTCTCACTACATCAGAAGACACACGGACGACTATAAGTTCGCCTGCGAACACTGCGGCAAGCGTTTCAAGATGGAGTGGGACTTGAAGTTCCACGTTGGCACCCACAGCAACTCCCAGCACATGTGCGACGTTTGCGGGAAATTTTATACGAGCAACTATTCGCTGTACAAGCATAGAAAGGTGGCCCATTTGAACGAGTACAAGTTTCAGTGCAGCGTCTGCAACAAAAGGCTACTCACGCAGGAGAATCTGGACAATCACATGCAACAGCACAGCAGAACGTACGAGTGCAAGGATTGTGGCAAGGTGTTCGCCTCGAAGAGGTACCTGGCGACACACACGACTACCCACACAGGGGTCAAACCGTATACTTGTCATATTTGCAAGAAGAACTTCAGAACGTCGCATATGAGGAACACGCATCTGTTGACGCACTCTGCGGAGAGGCCACATATCTGTGATCTTTGTGGACAGTCTTTTAAGAGGAGGTATTATATGATAGAGCATCGGAGGAAACATCCTGATGCTCACTTGTCGTCGCCTCCGGTGCCTCTTGGGAAAAAGAGGAACGTTGCTGAGTTGGATGGACAGATTGTGACTGAATTTCGAGCGGAGATTTCTTTGGATCGTGTTAGCTGCAAGAAGATGACCATCGGAACTTCCGGTCAACTTAGAGAAGACTCCGTCCCGACGCAGCAGGTCCACACCACGAAATCCAAAGAGAGCTCCGAAACGCCAACGACTATTTTCTTAAAGATGGACGGCGAAGAGCCACGTAAAGACGTTCAGAAAACAAATTGCGAGACGAGTTCTTACGTTTCGGATTCTCTGATACACCTCTGCGAAGTGAGCATCGATTACTGTACGTGCGACAAGTGTGGGATCAAGTTCCCCACCGAGAACATGCTGAACAAACACAAAATGTTCCACAAACTGCACTCGTGGATTCGCAAGAAACGTCTGCGTGCGAAGAATCAGCTAAAATCTTCGGGTAAACTAATCAAACAAACGAAGTCTCTGAAAATCCCAGAAAAGATGAAGTATGTCTGCATGTGCTGTAGCTTCACCTGCAACAGGAAGTCCACCATCACCATCCACATGAAGAAGAAACATTTAGAGATCTCGTGCATAATCTGCGACCTGAAATGCAACGATTACTCCACGTTGGCGAAGCACATGGAGAAACACAGGAACGCGAAGACAAAGTACTTCAAGTGCAACGTATGTAGCTTCGTCAGCAAGAAGAGGGGTGCTCTGGTGTCCCATGTGGTCCAAACGCATCGGAAGACTGATGACAAGAAGAAGAGGACGCCGACGAAGCGTGATGTCAAATCCAAGGAGAAGAAAAGTCCGGAAGAAGCAAAGGATCCGCTAATTGACTCGTGCACATCGTCAGAGTTCGACTGCAAGGACGAGGTGATATCAGAACCCGAGGACGACAAGAACTTCGACAAGGATCCTGTGGAACACTGCGACTTGTGTGACTTCACGTGTTCGAAGAGGAGCACACTGTACTCGCATAAACGCAGGCACAAGGTGGACGTAGCTGAGGTGTATTTCTGCAACGAGTGTCCCTTCAAGACCAACAAGAAGTCGTCCCTGTATTCGCACAGGAAGAGGAAGCACAGACCACCTAAACCTCTCACGGAAGATGGCCAGCCACAGTTGTTCTACTGCGCCCAGTGCGACTACAAGAACAAGAACAAGTACGAGCTGAGGGTGCACGTGGCCAGGAAGCACACCAACGATTTCAAGTTCTCCTGCGAGATCTGCGGCAAGAAGTTCAAGGTGAAAGGCGACCTGACAAACCACATACGCTTCAGCCATAAGGAACAGCCTGTCATGTGCGACGTCTGCGGTAAAACCTGTCCAAACAGTAATTCGTTGTACGTGCATCAGAAGTTCGCTCATTACAAGGCCCAGTACGAGTGCCATTTGTGCAAGAGGCGAATGGTCACCCAGGAGAACCTGAACGAGCATCTGATCAAGCAGCACGAGAACAGGAAGGCCGTGATGTGCGAGGAGTGCGGGAAGACCTTCTCCAGGAACAGCAGGCTGAAGGTGCACATGAGAGTCCACACCGGCGATAAACCGTACAATTGCACGATCTGCAGCAAGTCGTTCGCTCGTAGAACGGCCATGAAGCAGCATCTGCTGATACACACCGGGGTTAGGCCGTACGTTTGCGACATATGCGGGAAGGCGTTCACACAGAAGCCTGGCTTGATCAGCCACAGGAAGTCGCATCCTGGATCGCATCCGCCGCTTCCGAGAATCTTCATCGATCACATATTGCAGGACGTTATGAACAAATGA
Protein Sequence: MRSIVEEKSLQLINQKHKLGSQEDSKRKPASLLQRRRLLRVSKIRRRNRRSYETKDGSNSVQREEANKKSSIRRSTSRKLPDSNDCSAKLQSKPTQQEDLYKKLHDGTYTCDICQTTFEQKSKILRHITSKHSFHRPFKCQTCDKTFKYKCDLKAHKLVHQEVDSSLLHCCDKCDYRTKTKNNLKSHYIRRHTDDYKFACEHCGKRFKMEWDLKFHVGTHSNSQHMCDVCGKFYTSNYSLYKHRKVAHLNEYKFQCSVCNKRLLTQENLDNHMQQHSRTYECKDCGKVFASKRYLATHTTTHTGVKPYTCHICKKNFRTSHMRNTHLLTHSAERPHICDLCGQSFKRRYYMIEHRRKHPDAHLSSPPVPLGKKRNVAELDGQIVTEFRAEISLDRVSCKKMTIGTSGQLREDSVPTQQVHTTKSKESSETPTTIFLKMDGEEPRKDVQKTNCETSSYVSDSLIHLCEVSIDYCTCDKCGIKFPTENMLNKHKMFHKLHSWIRKKRLRAKNQLKSSGKLIKQTKSLKIPEKMKYVCMCCSFTCNRKSTITIHMKKKHLEISCIICDLKCNDYSTLAKHMEKHRNAKTKYFKCNVCSFVSKKRGALVSHVVQTHRKTDDKKKRTPTKRDVKSKEKKSPEEAKDPLIDSCTSSEFDCKDEVISEPEDDKNFDKDPVEHCDLCDFTCSKRSTLYSHKRRHKVDVAEVYFCNECPFKTNKKSSLYSHRKRKHRPPKPLTEDGQPQLFYCAQCDYKNKNKYELRVHVARKHTNDFKFSCEICGKKFKVKGDLTNHIRFSHKEQPVMCDVCGKTCPNSNSLYVHQKFAHYKAQYECHLCKRRMVTQENLNEHLIKQHENRKAVMCEECGKTFSRNSRLKVHMRVHTGDKPYNCTICSKSFARRTAMKQHLLIHTGVRPYVCDICGKAFTQKPGLISHRKSHPGSHPPLPRIFIDHILQDVMNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00962647;
90% Identity: iTF_00962647;
80% Identity: -