Basic Information

Insect: Megachile leachella
Gene Symbol: Hr39
Assembly: GCA_963576845.1
Location: OY756248.1:11489936-11495017[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 1.2 1.4e+04 -4.0 6.5 120 156 49 85 17 110 0.49

2 5 0.5 5.9e+03 -2.7 4.3 73 163 309 397 251 418 0.63

3 5 3 3.5e+04 -8.0 11.6 70 160 432 521 406 539 0.47

4 5 1.2e-08 0.00014 22.4 0.1 1 28 604 631 604 674 0.77

5 5 3e-71 3.5e-67 228.5 0.2 179 408 760 981 628 981 0.78

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	1.2	1.4e+04	-4.0	6.5	120	156	49	85	17	110	0.49
2	5	0.5	5.9e+03	-2.7	4.3	73	163	309	397	251	418	0.63
3	5	3	3.5e+04	-8.0	11.6	70	160	432	521	406	539	0.47
4	5	1.2e-08	0.00014	22.4	0.1	1	28	604	631	604	674	0.77
5	5	3e-71	3.5e-67	228.5	0.2	179	408	760	981	628	981	0.78

Sequence Information

Coding Sequence: ATGTCGGAGCAAAACGGGCCCAGCGAGGGCCCAGGACCAGGACCAGGACCAGGCCCCGCTTGGTGGCCAGCCTCGCAGTCCTGGAAAACGAACTCCTGTGCATCCGTCTCCTCATCCAGTACTTCCACTGCTCCAGACagctccgcctccgtctctgtctcctgCACCATTTCTACCTCTTCCCTGACGACTACCACTTCGACTACTTCCTCGACAAGTTGCTGTTCCTCGACTCCTAGCGGACCTTCGTGTACGATCACGGCTGCCCGTTCCACGGAAACAGGAAAGAACGTTTCTGTCACCACGATTAACGTACCGAACAATCAGGATATACACGATGGCAAAGGCATTTGTAAGTATCTAACCGGCCAGAATGGCGTCACAGTGTCCGTAGTTTCAAGCTGTGGCTCCGTATTGGACTGTGGAAATGCGAACGTTGTATCCACCACAGGGATCGGCATCAATAACGCCTCGCACAGCATCGGGATTGGCATTGGAGTTAATGTCCTTCAGTCTCAAAACACTGCGGATGACGATGCAGAAGATAGCGACGTAGAAATAAGCAAGATTGATTTTCGTGGAGTGAACTTGCGTACGAAGAAGAAACGAGACGTGCCGGGGAACCAGGGTGGAGAGAAAATAGGTGACGGAGATGCCGAAGATAGAAATGGTTGTTACGATGGAAATGATATCTCCCAGCAACAACCAGAGAGACCCATGTCATGGGAAGGTGAATTGTCTGACCAAGAAATGTCTTCCAATACAATTACAAATCAGGATACACACGAGGACACATCCATGGAAGGTGTCCAAGTTTGCGGTGCGAGTCCGGGCCCTATAGAgcaaaaatttcctataaaaccAGAACCTGACTTTCGGTCTAGTCCTGGATTTGCATTTGGTTCTTTTCATGACACTGGATTACCTTTGGCACATGGCCAACAgatgcaacaacaacaacaacgcaACATAGAGAACCTTGAACAGACACAACAAAATGATTTGCCTCTTCTCGTAGGGAAACTACTGGGTGGTTACAATAGTTCTACTCCAAATCACAGTCCAGTTCTAAATCCTAGACATCATTTGACTAAACATAGTCATACGAGATCACAGGTGCCGTCTCCAGATTCCGCAATTCACTCGGCATACAGCGTATTTAGTTCGCCAACACAGAGCCCTCATGCAGCACGCCATTCTGCTTTAGGAGCAGGAAGTCCGGTACCGTCTTCGTCGCTTTCTCTCTCGCGACACAGCTTCAACAATTCAACTTCCTCTTTATCGTTGTCACTATCGCATTCTCTCTCGAGGAACAATTCGGATGCCTCAAGCAGCTGTTACAGCTACGGTTCTCTTAGCCCACCTACGCATTCACCCGTCCAACAACCAAGACATCCGCAACATCATCAGCACCAGGTGGCCCAGGGAAGTCCGCTTCATCTGCCAGCAACAGCCTCGTCCATTGCTCATCATTATTCTTCCTCTACACCGGGTTCTGAACTCTCCCCTGAAGGACATACCGCTCCTGATGATCAAGAAGACTGTCGAATACCCTCAGCTCCTTCCAGTATCTCCACTAGACAACAACTGATCAATAGTCCATGTCCAATTTGTGGTGATAAGATCAGCGGTTTCCATTATGGAATCTTCTCGTGTGAATCATGTAAAGGATTCTTTAAACGCACCGTCCAAAACCGGAAAAATTATGTGTGCCTTAGAGGCGCGGGCTGTCCAGTCACCGTTGCCACCAGAAAGAAGTGCCCAGCCTGTCGTTTTGACAAGTGCCTCAATATGGGTATGAAGCTTGAGGCTATTAGAGAAGATCGCACCAGGGGCGGACGAAGTACCTATCAGTGTACGTACACTCTTCCAGCAAGTCTTGTGAGTAATTCTGCGAGCGGTATGACTAGTGACAAATTGGCCACGGGAGGGAATTGTAGTCCAGCTCCATCGGGAAGCGAACATCACTATCCTAGTAGACATCACTCGAATCATTCGCACAAGATACAGGTGGTGCCGCAACTTTTGCAAGACATTATGGACGTAGAACATTTGTGGCATTACAACGACAATGATCGCATGTCTGGAATTCAAGCTGGAATGAATGCTACTAGAAATAACGATTCGATGTTATTAGGAGTGGGTTCCGGAACTGGTTCTGGATCCGGAACAGGAAGTGACGGAAGTGTTGAGTGTCCCTCCAATGGAACAGCTGGAAATGGAAATTCCAACAACAGGAGAGACGACAGGTCATGTTCTAATGTTTCTGCTGTTAATAACGAACAACGAGCTACGTCTGTTACTAGTAGTTCCCAGATTGGTAGCAATACGAATGGCAATTCTACCCAGCATCCTGATTTTCTATCGAACCTTTGTAACATTGCTGATCATCGACtgtataaaatagtgaaatggtgCAAGAGTCTGCCGCTGTTTAAAAACATTTCCATTGACGATCAAATCTGTCTGTTAATTAACTCCTGGTGCGAGCTATTGCTCTTCTCGTGCTGCTTTCGCAGTATGAGTACTCCCGGTGAAATCAGAGTGTCTCTGGGCAAGTCGATTACATTAGAGCAGGCTAGACAGCTTGGCTTGGCGACTTGCATCGAGAGGATGCTCGCATTTACTAACAATTTGAGAAGGCTAAGAGTGGATCAGTACGAATATGTAGCGATGAAGGTAATAGTGTTGTTGACCAGTGATACAAGTGAATTGAAGGAACCTGAAAAGGTTAGAGCATCTCAGGAAAAGGCTTTACAGGCATTGCAACAATATACCATAGCAAGGTACCCAGAGATGCCTGCCAAATTTGGCGAGTTACTGTTAAGAATTCCAGATTTACAAAGAACATGCCAGGCAGGAAAAGAATTGTTAACTGCAAAACGTGCAGAAGGTGAAGGCAGCTCGTTTAATTTGTTGATGGAATTATTAAGAGGAGATCACTGA
Protein Sequence: MSEQNGPSEGPGPGPGPGPAWWPASQSWKTNSCASVSSSSTSTAPDSSASVSVSCTISTSSLTTTTSTTSSTSCCSSTPSGPSCTITAARSTETGKNVSVTTINVPNNQDIHDGKGICKYLTGQNGVTVSVVSSCGSVLDCGNANVVSTTGIGINNASHSIGIGIGVNVLQSQNTADDDAEDSDVEISKIDFRGVNLRTKKKRDVPGNQGGEKIGDGDAEDRNGCYDGNDISQQQPERPMSWEGELSDQEMSSNTITNQDTHEDTSMEGVQVCGASPGPIEQKFPIKPEPDFRSSPGFAFGSFHDTGLPLAHGQQMQQQQQRNIENLEQTQQNDLPLLVGKLLGGYNSSTPNHSPVLNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAARHSALGAGSPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRHPQHHQHQVAQGSPLHLPATASSIAHHYSSSTPGSELSPEGHTAPDDQEDCRIPSAPSSISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPASLVSNSASGMTSDKLATGGNCSPAPSGSEHHYPSRHHSNHSHKIQVVPQLLQDIMDVEHLWHYNDNDRMSGIQAGMNATRNNDSMLLGVGSGTGSGSGTGSDGSVECPSNGTAGNGNSNNRRDDRSCSNVSAVNNEQRATSVTSSSQIGSNTNGNSTQHPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLTAKRAEGEGSSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00733987;
90% Identity: iTF_00141880;
80% Identity: iTF_00962569;