Basic Information

Insect: Megachile lagopoda
Gene Symbol: -
Assembly: GCA_036983795.1
Location: CM072785.1:13866349-13868239[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 5.5e-05 0.0063 17.5 1.6 2 23 110 131 109 131 0.98

2 14 1.1e-05 0.0012 19.7 2.5 2 23 138 159 137 159 0.97

3 14 3e-06 0.00035 21.4 1.6 1 23 193 215 193 215 0.98

4 14 0.00029 0.033 15.2 0.2 1 23 221 243 221 243 0.98

5 14 1.9e-06 0.00022 22.1 1.8 1 23 249 271 249 271 0.97

6 14 7.4e-07 8.6e-05 23.3 1.7 1 23 277 299 277 299 0.96

7 14 2.9e-05 0.0033 18.3 0.6 1 23 305 327 305 327 0.98

8 14 2.7e-05 0.0031 18.4 6.8 1 23 333 355 333 355 0.97

9 14 7.5e-08 8.6e-06 26.5 1.0 1 23 360 382 360 382 0.97

10 14 0.00026 0.03 15.4 0.2 1 23 388 410 388 410 0.97

11 14 1.5e-06 0.00018 22.4 5.6 1 23 416 438 416 438 0.96

12 14 1.9e-06 0.00022 22.0 1.9 1 23 444 466 444 466 0.98

13 14 7.7e-06 0.00089 20.1 0.7 1 23 472 494 472 494 0.98

14 14 0.0003 0.035 15.1 2.3 1 23 500 523 500 523 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	5.5e-05	0.0063	17.5	1.6	2	23	110	131	109	131	0.98
2	14	1.1e-05	0.0012	19.7	2.5	2	23	138	159	137	159	0.97
3	14	3e-06	0.00035	21.4	1.6	1	23	193	215	193	215	0.98
4	14	0.00029	0.033	15.2	0.2	1	23	221	243	221	243	0.98
5	14	1.9e-06	0.00022	22.1	1.8	1	23	249	271	249	271	0.97
6	14	7.4e-07	8.6e-05	23.3	1.7	1	23	277	299	277	299	0.96
7	14	2.9e-05	0.0033	18.3	0.6	1	23	305	327	305	327	0.98
8	14	2.7e-05	0.0031	18.4	6.8	1	23	333	355	333	355	0.97
9	14	7.5e-08	8.6e-06	26.5	1.0	1	23	360	382	360	382	0.97
10	14	0.00026	0.03	15.4	0.2	1	23	388	410	388	410	0.97
11	14	1.5e-06	0.00018	22.4	5.6	1	23	416	438	416	438	0.96
12	14	1.9e-06	0.00022	22.0	1.9	1	23	444	466	444	466	0.98
13	14	7.7e-06	0.00089	20.1	0.7	1	23	472	494	472	494	0.98
14	14	0.0003	0.035	15.1	2.3	1	23	500	523	500	523	0.97

Sequence Information

Coding Sequence: AtggaagattttaaaataaaagatgaacCAATGGATATGTTAAACATAGACAGTCAGGTTATGGACGAAAACATTGTAAGCGTTGTACTTAAGGAAGAACCTGGTGATAGATTTGATCCCGACTACATGGAGGACATCTGCTCTGGGACATTCGAGAAGGTATTTTTACCTATCGAAAATAACGAAGTTGACTTCTCCAATGAAATGGTAAAACTCGAATTGGATGGAGAATCTAGTAGCCATCAGAATTGGACAGCGCAAATTGCTGGTACCAATTTATGTGATAAAGAAGATGGTGCTATGCAAAGGTTGCACTGCAGTGGAAACCAATGCGAAGTTTgccaacaaaattttcaagataattCCAGtttacatattcatatgttgACTCATGTTGGGATGAGCCCATTAGAATGTAATATCTGTCAAAAGCGATTTGCGTATAAATGGTGTTTACGCAGTCACATGCAGATGCACGTATTGGAAAAACCGTACGATAATGATCCGGTACATCAAGCGTTTATGAAAAGGCAAGATTCTGAGAACGATCAATCGATGAACGCGGGAGAAAGATTATTCGAATGCGATGTTTGTCACGCAACGTTTAAGGAGAAATCTAGTCTGAATCGACATGTGCTTACCCATACGGAAGAAAGACCATACAAATGCGATATATGCGTTGCAGCATTTAGGGAAAaggcaaaattaaatatgcacATGACGTTACACGAAGGAGAAAAACAGTTCAAATGTACGATGTGTTACAGATCGTTTACACAGAAAACAGCACTAAATAATCATATGTTAGCGCACAGTGGTGAGAAACCGCATGCATGCAATATTTGCGAGAAAACATATAGACGAAAGTCAGAGTTAATAAGACACACGATGGTTCACACCGGCGAAAGACCATACGAATGCAAAGAATGTCTGATGACTTTTCGGGAAAAGGCGaaattaaattctcacatGCTCGTTCATACAGGTGAAAAACCACACGAGTGTCATATATGTCATAAAGCGTGCGCTCGCAAATCTGACCTTAACAGTCATATGCTACTGCATACCGGTGGTCAGTACGATTGTAAAGTTtgtgacaaaatatttactcgcAAATCTGATTTAAATCGGCATACTTTGATACATACAGGCGAAAAACCATTTGCTTGTGGTTTGTGCGACATGGCTTTCAGAGAAAAAACTAGATTAAATTCTCATATGCTTATTCATACTGGGGATAAACGACACGCTTGTCACATTTGCCAGAAAACGTTTAAAGAAAAGTCTTCGTTGCGAAAACATATGTTAAGTCACACTGGTGACAGACCATACGAATGTTACGTGTGTCATAAAGCATTTACACAAAAAACAACGTTAAACAGCCACATATTAGTACACGCAGCAGAACGACCGTACGAGTGCAGTGCgtgtcaaaaaatatttaaggacaaagcaacattaaaaaaacatttatcAGTACATACGAACGAAAAAACTCACGAATGtctaatttgtttaaaaaagtttGCCCACAAAGCTGCATTAAATAGTCATTTATCAACAAATCATACGACCTAA
Protein Sequence: MEDFKIKDEPMDMLNIDSQVMDENIVSVVLKEEPGDRFDPDYMEDICSGTFEKVFLPIENNEVDFSNEMVKLELDGESSSHQNWTAQIAGTNLCDKEDGAMQRLHCSGNQCEVCQQNFQDNSSLHIHMLTHVGMSPLECNICQKRFAYKWCLRSHMQMHVLEKPYDNDPVHQAFMKRQDSENDQSMNAGERLFECDVCHATFKEKSSLNRHVLTHTEERPYKCDICVAAFREKAKLNMHMTLHEGEKQFKCTMCYRSFTQKTALNNHMLAHSGEKPHACNICEKTYRRKSELIRHTMVHTGERPYECKECLMTFREKAKLNSHMLVHTGEKPHECHICHKACARKSDLNSHMLLHTGGQYDCKVCDKIFTRKSDLNRHTLIHTGEKPFACGLCDMAFREKTRLNSHMLIHTGDKRHACHICQKTFKEKSSLRKHMLSHTGDRPYECYVCHKAFTQKTTLNSHILVHAAERPYECSACQKIFKDKATLKKHLSVHTNEKTHECLICLKKFAHKAALNSHLSTNHTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01539746;
90% Identity: iTF_00087361;
80% Identity: -