Mlys004734.1
Basic Information
- Insect
- Mechanitis lysimnia
- Gene Symbol
- -
- Assembly
- GCA_036026155.1
- Location
- JAYRBX010000033.1:493575-505757[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 28 0.23 35 6.5 0.1 1 20 207 226 207 228 0.93 2 28 0.0052 0.79 11.7 0.6 2 23 256 278 255 278 0.95 3 28 2.8 4.3e+02 3.1 3.3 1 23 301 323 301 323 0.97 4 28 0.002 0.31 13.0 0.8 1 23 327 349 327 349 0.98 5 28 0.02 3.1 9.9 1.2 1 23 354 377 354 377 0.92 6 28 0.044 6.8 8.8 0.4 2 23 385 407 384 407 0.93 7 28 0.00076 0.12 14.3 6.1 1 23 414 436 414 437 0.95 8 28 0.0072 1.1 11.3 1.2 1 23 443 465 443 465 0.95 9 28 1.9e-06 0.00029 22.6 2.2 2 23 472 493 471 493 0.96 10 28 7e-06 0.0011 20.8 2.2 1 23 499 521 499 521 0.98 11 28 0.0014 0.22 13.5 2.5 1 23 623 646 623 646 0.96 12 28 3.6 5.5e+02 2.8 0.1 2 9 672 679 671 694 0.85 13 28 0.053 8.1 8.6 4.1 3 23 719 739 717 739 0.96 14 28 0.1 16 7.6 0.9 1 23 743 765 743 765 0.97 15 28 0.19 28 6.8 0.3 1 23 772 795 772 795 0.91 16 28 0.0042 0.64 12.0 1.8 2 23 803 825 802 825 0.95 17 28 1.8e-06 0.00028 22.6 0.9 2 23 831 853 830 853 0.97 18 28 1 1.5e+02 4.5 1.5 1 23 859 882 859 882 0.94 19 28 2.3e-05 0.0036 19.1 0.7 1 23 888 911 888 911 0.98 20 28 0.0017 0.26 13.2 0.0 1 23 1002 1025 1002 1025 0.94 21 28 0.036 5.4 9.1 0.5 1 20 1096 1115 1096 1118 0.91 22 28 0.0005 0.076 14.9 1.2 1 23 1122 1144 1122 1144 0.98 23 28 0.25 38 6.4 1.8 1 23 1149 1172 1149 1172 0.90 24 28 0.032 4.8 9.3 2.0 2 23 1180 1202 1179 1202 0.95 25 28 4e-05 0.0061 18.4 0.8 2 23 1210 1232 1209 1232 0.97 26 28 0.0029 0.45 12.5 1.5 1 23 1237 1259 1237 1259 0.95 27 28 4.4e-05 0.0067 18.3 5.2 1 23 1265 1287 1265 1287 0.98 28 28 0.0015 0.23 13.4 4.4 1 23 1293 1316 1293 1316 0.98
Sequence Information
- Coding Sequence
- ATGGAGCCGAATATAAGTGACGGTATGTGCCGGTGTTGTGCATCAGAAGGTAGTTCTAAGGACATTCAAACAACATACCATTGGATGGGTGTAGAAGAAATTTATTCCGATATGTTAAaggattgttttaatatcacaCTTGCCACATCAGAAGTAATCCACAATGGTGGTATATGTGAACTGTGCATCTCTCAGCTCCGCAATGCTTACAATTTCAAACGGCAAGTCCAAGTCACAGAAGAACAGTTCAAGAAGAAAGTTCGGGAATCAGTGTTTGAATCGAGCTCAATCAAGCTGGAGATCTCTCAGGATGATGTGGAGTCTGATAATGTGGCATCTGAAAATTTATCTGATGCCGACTATGAAGTGCCAATAAAAGAAGAGAAGCAGGAGGAGAAACCCAAGAAGCGTCAAGCGAAGGCCTCCACCTCCAAAGCAAAAAAGACCAAGACTGAAGGGGAGACCTCGAAACGAACGGACGGCGAACCCAAAcgcaagaaaaagaaaaagaaatcgGAGGTAAGCGCAACACCAGAGCGCATAGAACACAGAGTCAACTTAACTGCTATACTCCAGTTCTCCAACGCGAGTCCTTTCAGGGACAAGACCATGAAAGGCTTCTCGTGCCTCTACTGCGCCAAGAGTTTTCAGGGTATTGATGAGCTCCGAGATCACACAGCTCAGCAGAAGGAAAAAGACAAAATTAACGCAATGCTGGACTACAAACTAAGCTATAACCCAATCAAACTTGACATAACTAACCTTCAATGTACCGTCTGCCATAAAGACTTGAAAGATCTTAACGAACTGAAAGAGCATTTGATCTCCGttcataataaaactatacacaAGAATATTAAAGATACGATTCTACCCTTCAGATTGGAGAATGGTCAAAATTTCACATGCGTCATATGTTCAGTCGTtcacatttcttttaaaaatctctATCATCATATGAGTAGTCATTATCGTAATTATTGCTGTAAGAAGTGCGGTGCTGGGTACATCACTATAGCAGCGTTGAGGAAGCACGGTAAGACGCACTATCAGGGACACTTTCCGTGCGATTTCTGTGATAAATCCTACACTTCTCTCACCAAGAAACGGAATCACGAAAAGGGTGTACATACAGGTGGCTGGTTGAGGAACAAGTGTCCTCATTGTCCTGAAATATTTGTCAGTTACTACGACCGAAGCGAGCACCTGGTGAAGGTTCACAACGAGGCTCCTGTAGTATATCCTTGCAATGCCTGCAATAAAACGTACAAAAAGAAATTCGAACTCAACCGACATATCAAACACCATCATCTTCAGCAGAGAAGCTTCTTATGCGATAAATGCAATGCAAAGTTCTTCTCGAAGCGAGGACTAGTGGATCACATGACGCGGCACACGGGCTCCGAGATATGTTCTTGTGATATATGCGGGAAGGCATTTTCGAGGATGAGAACATTGAGGGAACACATGAGAATGCACGAAGACGATAAACGCTTCCAATGTGAAGTTTGTAAAAAGACCTTCATGCAAAAGAGCAGTTTGAAGAGTCACGTCAAGCTCCACCAGGACGACCTGGATATATTTAAAGAGTTTGATGATGTAAAGCATCTCATTGATGACAGGGAGATGACTCTCAAACAAATAGCCGCAGAGAACAAAGTGAGATCAATCGcggtcaaattaaaaaatcaaatggtCGgaagccgaaaaaaaaggaaaacgaCAGTAAAGGAGGAAAGCGAAGACCCTAATAATATAGGGTGTCGCGAAAAGAATCCGCGAGAGATACAGAAGCAGTGGCACAATCTAGCCACCCTTCTTAAATATTCTAACGCCACCCCGTTCAAGAATAGAAACGATGCGGGCTATGTGTGCGCTTATTGCTTTAAACACTTCCCTGATCCAAGTGTTCTGAGACATCACACTAACAACGACCATATCAAAGAAAAACCGACATATAAAGCTTGTTcgttaataagtaattttgtaGCATTGTTGGATATATTCGATTTGAAATGCACTATTTGCGGAAAAGCTATGgacagtattaatattttaagcgaGCATCTAGTCAAAGAACACGATAAGCCGTATTATTTAGGCGTGACTGATTATTTTCAACCGTTCAAGCTTACAAAGTTGCAGCAGATCAATTGCTGTTTGTGTAACGAACGATTTCACAATATGAAGCTGTTGATGCAACACATGAATGTACATTATCGAAATTTTATTTGCACTTCATGCGGTGCGGGATTCGTGAACAGTTGTCGTTTGGGCAGACACGAGACAACTCACCTGAAGAAGAGATCTAACTTTGCATGTAGATACTGTGATCAGGTTTTCGATGCTGAATCAAAAAAGAAGGCTCACGTCAATGCTAAGCATAAAGGCATCGAAGGTCACAGTGTATGCCAAATTTGTAAAGCTagatttaagaattattatcagAAAACGAGGCATATGACAAAAGTGCACAAAGTGGAAGGCATTAAATGTGATATGTGCGATAAAAGATTTGATTTGAAGTCTAATTTGAAGCTGCACATGAGGAGCGTACACTTGAACGCGAGGCCGTACGTATGTCCGGTTTGCTCAATGGGTTACTTGACAAGGCGCCACATGTTCACTCACTACATTTCTACACACACGAATGAAAGAAACTATAAATGTGATAGCTGTAGTAAGGCGTACGCTACTCAGAATAGTTTGAGGAAACATATTAATTCGATCCACGGTGTCGAGTCTCAAACAACATTAATCgaaataattatcaaacaaGAACCGATGTCTGACTCGGAACAACCCGAAGATTCTAAACCCGACACTGTGTTCAATACTGAACcggataaaacaaaaaagaaagataagGATCTAAAGAAAAGTGCTTCTGATAGAAGATCTAAAAAGGATCAAATCATTGAAAtggaaaaacatttaaagaatattagcACTATCCTTCTTCACACAAACGCTACTCCCATTAGATATCACGATGGTGCGAATTATGTTTGTGCACTTTGCAAGGAAACGTTTCCCATGCCCTCGGATCTAAAACTTCACGTGCTAGAGGAGCATGATGAAATAGACAAGTCTTCTTTCATGGAAGGTCATAGACTAACTTCCTATGTGGTGAAACTGGACATAACAAATTTGCGTTGTCTTATTTGCCACAATGATATTGAAAGTTTCGATCCAATGTTCGATCATCTCAAGTCGGTTCACGGAAAAGAAATGCACACGGATATACCCAACCATATATTGCCTTTTCGTTTCGTTGGTAACGGTTTTGATTGCGTCGTCTGTCCTAAATCTTTCGAACACTTCAAACTCGTTCAGGAACATATGCCTGTGCATTACAGAAATTATATATGTGAAACTTGCCATGCTCCTTTTGTTAATAAGAGAACTCTTCAAAATCACGCGAACAGGCATAAAAAAGGCGATTTTCCTTGCAGTCAATGTAcgaaaatatttgatacaaatcGAAAGAAATTGAATCACGAGAAATTTGTTCACGATGGTGACTATAAGCGGAAAAAGTGTCCATTCTGTCAGGAAAAGTTTACAAATTATGCTAAGAAACGATCTCATATGGTTAAGGAGCACGGAGCTGAGCCGTTGTCTGTTAAATGTGATATATGTAATAAGGTATTTAGTACACGAGCGAGATTAAGAGGTCACACCCGCAGAGACCACATGGAATGTGAACACGCCTGTAATAATTGTGAAATGAGGTTTTACACACAGCTGGAGCTAGTCAAGCACATGGTGAAGCATTCCCCCCTCAAAGAATATCACTGTGATGTCTGTAAGAAGTCGTACGCGAGGAAACACACTCTCCGCGAACATATGAAGATACACTCTAATATTCGGAACTTCAAGTGTGATATCTGTGCATTCACATTCGTTCAAAAGTGTAGTTGGAAATCGCATATGCGAAAGAAACATAAGATACAGGTTAAATAG
- Protein Sequence
- MEPNISDGMCRCCASEGSSKDIQTTYHWMGVEEIYSDMLKDCFNITLATSEVIHNGGICELCISQLRNAYNFKRQVQVTEEQFKKKVRESVFESSSIKLEISQDDVESDNVASENLSDADYEVPIKEEKQEEKPKKRQAKASTSKAKKTKTEGETSKRTDGEPKRKKKKKKSEVSATPERIEHRVNLTAILQFSNASPFRDKTMKGFSCLYCAKSFQGIDELRDHTAQQKEKDKINAMLDYKLSYNPIKLDITNLQCTVCHKDLKDLNELKEHLISVHNKTIHKNIKDTILPFRLENGQNFTCVICSVVHISFKNLYHHMSSHYRNYCCKKCGAGYITIAALRKHGKTHYQGHFPCDFCDKSYTSLTKKRNHEKGVHTGGWLRNKCPHCPEIFVSYYDRSEHLVKVHNEAPVVYPCNACNKTYKKKFELNRHIKHHHLQQRSFLCDKCNAKFFSKRGLVDHMTRHTGSEICSCDICGKAFSRMRTLREHMRMHEDDKRFQCEVCKKTFMQKSSLKSHVKLHQDDLDIFKEFDDVKHLIDDREMTLKQIAAENKVRSIAVKLKNQMVGSRKKRKTTVKEESEDPNNIGCREKNPREIQKQWHNLATLLKYSNATPFKNRNDAGYVCAYCFKHFPDPSVLRHHTNNDHIKEKPTYKACSLISNFVALLDIFDLKCTICGKAMDSINILSEHLVKEHDKPYYLGVTDYFQPFKLTKLQQINCCLCNERFHNMKLLMQHMNVHYRNFICTSCGAGFVNSCRLGRHETTHLKKRSNFACRYCDQVFDAESKKKAHVNAKHKGIEGHSVCQICKARFKNYYQKTRHMTKVHKVEGIKCDMCDKRFDLKSNLKLHMRSVHLNARPYVCPVCSMGYLTRRHMFTHYISTHTNERNYKCDSCSKAYATQNSLRKHINSIHGVESQTTLIEIIIKQEPMSDSEQPEDSKPDTVFNTEPDKTKKKDKDLKKSASDRRSKKDQIIEMEKHLKNISTILLHTNATPIRYHDGANYVCALCKETFPMPSDLKLHVLEEHDEIDKSSFMEGHRLTSYVVKLDITNLRCLICHNDIESFDPMFDHLKSVHGKEMHTDIPNHILPFRFVGNGFDCVVCPKSFEHFKLVQEHMPVHYRNYICETCHAPFVNKRTLQNHANRHKKGDFPCSQCTKIFDTNRKKLNHEKFVHDGDYKRKKCPFCQEKFTNYAKKRSHMVKEHGAEPLSVKCDICNKVFSTRARLRGHTRRDHMECEHACNNCEMRFYTQLELVKHMVKHSPLKEYHCDVCKKSYARKHTLREHMKIHSNIRNFKCDICAFTFVQKCSWKSHMRKKHKIQVK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00842866; iTF_00420709; iTF_00419903;
- 90% Identity
- -
- 80% Identity
- -