Dmel044797.1
Basic Information
- Insect
- Danaus melanippus
- Gene Symbol
- -
- Assembly
- GCA_010014825.1
- Location
- JAAAKD010006418.1:1-6027[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 29 0.064 12 8.3 0.1 1 20 50 69 50 71 0.94 2 29 0.01 1.9 10.8 0.6 2 23 99 121 98 121 0.93 3 29 2.4 4.4e+02 3.3 3.3 1 23 144 166 144 166 0.97 4 29 0.0017 0.31 13.2 0.8 1 23 170 192 170 192 0.98 5 29 0.017 3.1 10.1 1.2 1 23 197 220 197 220 0.92 6 29 0.038 6.9 9.0 0.4 2 23 228 250 227 250 0.93 7 29 0.00065 0.12 14.6 6.1 1 23 257 279 257 280 0.95 8 29 0.0061 1.1 11.5 1.2 1 23 286 308 286 308 0.95 9 29 1.8e-06 0.00032 22.6 2.0 2 23 315 336 314 336 0.96 10 29 5.9e-06 0.0011 21.0 2.2 1 23 342 364 342 364 0.98 11 29 0.012 2.2 10.5 3.3 1 23 458 481 458 481 0.94 12 29 3.5 6.3e+02 2.8 0.2 2 23 507 529 506 529 0.89 13 29 0.051 9.3 8.6 5.1 3 23 554 574 552 574 0.96 14 29 0.0011 0.2 13.9 0.6 1 23 578 600 578 600 0.97 15 29 0.095 17 7.7 0.2 1 23 607 630 607 630 0.91 16 29 0.0085 1.6 11.0 1.9 2 23 638 660 637 660 0.95 17 29 1.5e-06 0.00028 22.8 1.2 2 23 666 688 665 688 0.97 18 29 1.8 3.4e+02 3.7 1.0 1 23 694 717 694 717 0.89 19 29 2.8e-07 5.1e-05 25.2 1.2 1 23 723 746 723 746 0.98 20 29 0.006 1.1 11.5 0.0 1 23 838 861 838 861 0.94 21 29 8.2 1.5e+03 1.6 0.4 2 23 888 910 887 910 0.93 22 29 0.0029 0.53 12.5 0.8 1 23 932 954 932 954 0.96 23 29 0.00047 0.087 15.0 0.7 1 23 958 980 958 980 0.97 24 29 0.071 13 8.1 1.1 1 23 985 1008 985 1008 0.90 25 29 0.0051 0.93 11.7 1.8 2 23 1016 1038 1015 1038 0.95 26 29 0.00018 0.032 16.3 1.0 2 23 1046 1068 1045 1068 0.97 27 29 0.00023 0.042 16.0 1.5 1 23 1073 1095 1073 1095 0.97 28 29 1.8e-06 0.00033 22.6 2.3 1 23 1101 1123 1101 1123 0.99 29 29 0.0025 0.45 12.7 5.7 1 23 1129 1152 1129 1152 0.98
Sequence Information
- Coding Sequence
- ACGGACGGCGAACCGCCCAAAcgcaagaaaaagaaaaagaaatcggAGGTAAGCGCTACACCTGAGCGCATTGAACACAGGGTCAACCTGACAGCCATATTGCAGTTCTCCAATGCGAGCCCGTTCCGGGATAAGACCATGAAAGGCTTCTCCTGCCTCTACTGCGCGGAGAGTTTTCAGGATATTGACGAACTCAGAGCGCATACGTCCCAGCAGAATGAGAAagacaaaataaacacaatgcTTGATTACAAACTTAGCTATAATCCTATCAAACTGGACATAACTAATCTCCAATGCACCGTCTGCCATAAAGATTTAAAGGATCTGAACGAGCTCAAAGACCATTTAGTGTCTGTTCACAATAAGACCATACATAAGGATATCAAGGACACAATACTGCCGTTCAGATTGGAGAACGGTCATAACTTCACTTGCGTCATATGTTCTGTTGTGCACATATCTTTCAAGAATCTGTATCATCACATGAGCAGCCATTATCGTAACTATTGCTGTAAGAAATGCGGTGCCGGTTACATCACCATAGCGGCGTTGAGGAAGCACGGCAAAACTCACTATCAAGGTCATTTCCCTTGCGACTTTTGTGATAAATCATACACCTCGCTGACCAAGAAACGTAATCACGAAAAGGGCGTCCACACAGGCGGCTGGCTGAGAAACAAATGTCCACACTGTCCCGAAATTTTCGTCAGCTATTACGACCGCAGCGAGCACTTGGTCAAGGTTCACAACGAAGCACCAGTCGTGTATCCATGCAACGCGTGCAACAAGacatacaaaaagaaattcgAATTAAACAGACACATAAAGCACCACCACTTACAGCAGAGGAGTTTCCTCTGTGATAAATGCAACGCTAAGTTCTTTTCGAAGCGCGGTCTCGTTGATCACATGACACGGCATACGGGTTCGGAGATGTGTTCCTGTGACGTATGCGGTAAAGCCTTCTCCAGGATCAGGACCCTAAGAGAGCATATGCGGACGCACGAAGACGACAAACGCTTCCAATGCGAGGTCTGCAAGAAGACGTTCATGCAGAAGAGCAGTCTCAAGAGTCACGTGAAGCTACATCAGGACGACTTGGACATATTCAAAGAGTTTGATGATGTCAAGCATTTAATAGACGACAGAGAGATGACTCTCAAACAAATAGCTGCCGAGAACAAGATGAGGTCTATAGgaACCCGAAAAAAACGGAAAACGACAGTAAAGGAGGAAAGCGGGCAGACGTTGAATAGTGTTGTGTTCCGTGAAAAGCATCTACGTGAGATGCAGAAGCAGTGGCACAATCTGACTACCCTCCTTAAATATTCTAACGTTACCCCGTTCAAGGACAGAAACGACGCGGGTTATATGTGCGCGTATTGCTTTAAGACCTTCCCAGATCCCAATGTACTAAGACATCACACCCACTATGACCATGTCAAAGAGAAACCAACTTACAAGGCCGGTTCTGGCATAAGCAGTTTCGTAGTCTTTTTGGATATAGTCGATTTAAAATGCACGTTATGCGGCTTGTCAATGGAGAGCATTAATTTTCTTACCGAGCACCTAGTCAAAGAAcacgacaaaaaatattatttaggcgTAACCGATTACTTCCAGCCGTTCGTTCTAACTGACGAGCAGCAGATGCACTGCTGTCTGTGTGACGAGGTTTTccataatatgaaattattgatGCAACACATGAATGTGCATTATCGTAATTTCATATGCACCACATGCGGTGCTGGTTTCGTGAACAGTTTTCGCCTAAAAAGGCACGAGACGACACATCTAAAGAAGAAAACCGGTTTCGCCTGCCGGCATTGCGGGCTGGTTTTCGCGGCTGAGTCGAAAAAGAAAGCTCACGTGAACGCCGAGCATAAGGGCATAGAAGGGCACAGCGTGTGTCAAATATGTAAATCCAGATTTAAGAATTACTATCAGAAGACCAGGCATATGATGCAAGTACATAACGTGGAAGGTATTAAATGTGATAAATGTGATAAGCGGTTTAATCTTAAATCTAATCTCATGCTTCACATGCGGAGTGTGCATTTAAAAGAGAGACCATACGAGTGCTCGGTATGCAGCATGGGATTTTTTATAAAGCGGCACATGCTAGGACATTATATGGCCACGCATACTAATgagagaaaatttaaatgtgacGTATGCGGCAAGGCGTATGCTACACAAAATAGCTTAAGGAAACATATGAAGAAGAATCACGGTGTGGAGAATCAAACAACACTAATCGAAATTGTTATCAAACAAGAACCTATGTCTGACTCGGAACTACCAGAGGACGCTAAACCTGATacagttttcaatataaaaccaGAGAACGATAGAAGTGAGGAGGTCAAAGATGTAAAGAAAACTGCATCCGAAAAAAGATCCAAAAAAGATCAGATTATAGAAATGgaaaagcatttaaaaaatataagcacaATACTACTTAACACGAACGCTACGCCCATAAGATATCACGACGGTGCCAATTACGTTTGTGCACTCTGCCCCGAAACATATCCTTTGCCATCAGATTTGAAAGTTCACGTATTAGAGGAACACGATGAAATAGATAAGTCGTCTTTCATGGAAGGTCACAGGTTGACTTCCTACATGGTCAAGTTAGATATAACAAATTTGCGTTGTTTGATTTGCCACAACGATGTAGAGAGCTTCGACCCTCTTTTCGATCATCTCAAATCGGTGCACGGCAAAGAAATGCACACTGATATACCAAACCACATCCTGCCCTTCAGATTCGTTGGGAACGGTTTCGATTGCGTCGTGTGTCCCAAGTCCTTTGAACATTTCAAACTAGTCCAGGAGCACATGACTGTGCATTACAGGAATTACTTCTGCGAAACTTGTAATGCACCCTTTGTTAATAAACGAACCTTACAGAATCATGCGAACAGGCACAAGAAAGGTGATTTCCCGTGCAGCCAATGCCCAAAAATATTTGACACCAATCGTAAGAAACTGAATCACGAAAAATTTGTTCACGACGGTGATTACAAGCGAAAGAAATGCCCGTACTGTCAGGAGAAGTTCACAAATTATGCCAAGAAGAGGTCTCATATGGTAAAAGAGCATGGAGCTGAGCCTCTGTCAGTGAAATGTGATATTTGCAAGAAGATATTCAGCACTCGGGCGAGATTAAGAGGGCACACTCGCAGGGATCATATGGAGTGCCAGTACGCGTGCCATGATTGTGATATGCGATTCTTCACGAATTTGGAACTCGTCAAGCATATGGTGAAACACTCGCCATTAAAGGAGTACCAGTGCGACATTTGTAAGAAGGCATACGCGAGAAAACACACGCTCCGAGAACACATGAAGATACATTCCaatataagaaactttaaatGCGACTTGTGTTCCTTTACTTTTATACAGAAATGCAGCTGGAAGTCACACATGCGCAAAAAACACAAAATGCAGGTCTAA
- Protein Sequence
- TDGEPPKRKKKKKKSEVSATPERIEHRVNLTAILQFSNASPFRDKTMKGFSCLYCAESFQDIDELRAHTSQQNEKDKINTMLDYKLSYNPIKLDITNLQCTVCHKDLKDLNELKDHLVSVHNKTIHKDIKDTILPFRLENGHNFTCVICSVVHISFKNLYHHMSSHYRNYCCKKCGAGYITIAALRKHGKTHYQGHFPCDFCDKSYTSLTKKRNHEKGVHTGGWLRNKCPHCPEIFVSYYDRSEHLVKVHNEAPVVYPCNACNKTYKKKFELNRHIKHHHLQQRSFLCDKCNAKFFSKRGLVDHMTRHTGSEMCSCDVCGKAFSRIRTLREHMRTHEDDKRFQCEVCKKTFMQKSSLKSHVKLHQDDLDIFKEFDDVKHLIDDREMTLKQIAAENKMRSIGTRKKRKTTVKEESGQTLNSVVFREKHLREMQKQWHNLTTLLKYSNVTPFKDRNDAGYMCAYCFKTFPDPNVLRHHTHYDHVKEKPTYKAGSGISSFVVFLDIVDLKCTLCGLSMESINFLTEHLVKEHDKKYYLGVTDYFQPFVLTDEQQMHCCLCDEVFHNMKLLMQHMNVHYRNFICTTCGAGFVNSFRLKRHETTHLKKKTGFACRHCGLVFAAESKKKAHVNAEHKGIEGHSVCQICKSRFKNYYQKTRHMMQVHNVEGIKCDKCDKRFNLKSNLMLHMRSVHLKERPYECSVCSMGFFIKRHMLGHYMATHTNERKFKCDVCGKAYATQNSLRKHMKKNHGVENQTTLIEIVIKQEPMSDSELPEDAKPDTVFNIKPENDRSEEVKDVKKTASEKRSKKDQIIEMEKHLKNISTILLNTNATPIRYHDGANYVCALCPETYPLPSDLKVHVLEEHDEIDKSSFMEGHRLTSYMVKLDITNLRCLICHNDVESFDPLFDHLKSVHGKEMHTDIPNHILPFRFVGNGFDCVVCPKSFEHFKLVQEHMTVHYRNYFCETCNAPFVNKRTLQNHANRHKKGDFPCSQCPKIFDTNRKKLNHEKFVHDGDYKRKKCPYCQEKFTNYAKKRSHMVKEHGAEPLSVKCDICKKIFSTRARLRGHTRRDHMECQYACHDCDMRFFTNLELVKHMVKHSPLKEYQCDICKKAYARKHTLREHMKIHSNIRNFKCDLCSFTFIQKCSWKSHMRKKHKMQV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00958812;
- 90% Identity
- iTF_00419903;
- 80% Identity
- -