Basic Information

Gene Symbol
-
Assembly
GCA_028829205.1
Location
JAPOND010000136.1:1108947-1120555[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 27 0.12 10 7.5 0.1 1 20 208 227 208 229 0.94
2 27 0.015 1.3 10.3 0.9 2 23 257 279 256 279 0.93
3 27 4.4 3.8e+02 2.5 3.0 1 23 302 324 302 324 0.95
4 27 0.0021 0.18 13.0 0.8 1 23 328 350 328 350 0.98
5 27 0.021 1.8 9.9 1.2 1 23 355 378 355 378 0.92
6 27 0.046 3.9 8.8 0.4 2 23 386 408 385 408 0.93
7 27 0.00079 0.068 14.3 6.1 1 23 415 437 415 438 0.95
8 27 0.0074 0.64 11.3 1.2 1 23 444 466 444 466 0.95
9 27 1.9e-06 0.00017 22.6 2.2 2 23 473 494 472 494 0.96
10 27 7.2e-06 0.00062 20.8 2.2 1 23 500 522 500 522 0.98
11 27 1.4e-05 0.0012 19.8 0.9 1 23 624 647 624 647 0.97
12 27 0.015 1.3 10.3 4.3 2 23 719 740 718 740 0.97
13 27 0.0029 0.25 12.6 0.5 1 23 744 766 744 766 0.97
14 27 0.036 3.1 9.1 1.3 1 23 773 796 773 796 0.96
15 27 0.0037 0.32 12.2 1.3 3 23 805 826 803 826 0.95
16 27 8e-05 0.0069 17.5 0.2 2 23 832 854 831 854 0.95
17 27 0.65 55 5.2 0.6 1 23 860 883 860 883 0.87
18 27 5.6e-05 0.0048 18.0 0.4 1 23 889 912 889 912 0.98
19 27 0.0042 0.36 12.1 0.0 1 23 1003 1026 1003 1026 0.94
20 27 0.0024 0.21 12.8 1.3 1 23 1097 1119 1097 1119 0.97
21 27 0.00032 0.028 15.6 0.3 1 23 1123 1145 1123 1145 0.98
22 27 0.03 2.6 9.4 1.1 1 23 1150 1173 1150 1173 0.90
23 27 0.0061 0.53 11.5 1.8 2 23 1181 1203 1180 1203 0.95
24 27 4.1e-05 0.0035 18.4 0.8 2 23 1211 1233 1210 1233 0.97
25 27 0.0035 0.3 12.3 0.8 1 23 1238 1260 1238 1260 0.95
26 27 5.6e-05 0.0048 18.0 4.2 1 23 1266 1288 1266 1288 0.98
27 27 0.00041 0.035 15.3 4.8 1 23 1294 1317 1294 1317 0.98

Sequence Information

Coding Sequence
ATGATGCAGGATAATATAGGTGACGGTATGTGCCGGTGTTGTGCGTCGGAAGGTAGTTTTAAGGACTTTCAAACAACATACCATTGGATGGGTGTTGAAGAAATTTATTCGGATATGTTAaaagattgttttaatatttcaCTTGTCTCGTCAGAAGCAATGAACAATGGTGGTATATGTGAAGTGTGCGTCACTCAGCTCCGCAATGCATTCAATTTTAAACGGCAGGTCCAGCTCACAGAAGAACAGTTCAAGAAGAAGGTTCGGGAATCGGTgttaaaatCAGGCACAATCAAGTTGGAGATGTCTCAGGAGGATGTTGATTCAGATAATGTGGCTTCCGACAACCTGTCTGATGCTGACTATGAAGTGCCAATAAAAGAAGAGAAGCAGGAGGACAAGCCCAAAAAGAGACAAGCTAAGGCGTCCACTTCCAAGGCGAAGAAGCCCAAGACTGATGGAGAGACCTCGAAACGAACGGACGGCGAACCCAAACgcaagaaaaagaaaaagaaatcgGAGGTAAGCGCAACACCAGAGCGCATTGAACACAGAGTCAACTTGACTGCAATACTCCAGTTCTCCAATGCAAGTCCCTTCAGGGACAAGACCATGAAAGGCTTCTCGTGCCTCTACTGCGCCAAGAGTTTTCAGGGTATAGATGAACTCCGAGCCCACACAGCTCAGCAGAAGGAAAAGGACAAAATTAACGCTATGCTCGATTACAAACTGAGTTATAACCCTATCAAACTAGATATAACAAATCTACAATGCACTGTTTGCCATAAAGACTTGAAAGATCTTAACGAACTCAAAGAACATTTAGTCTCCACTCACAATAAaactatacacaaaaatatcaaagataCAATCCTACCCTTCAGACTGGAGAATGGTCAAAATTTTATGTGTGTTATCTGTTCGGTTGTTCACATTTCGTTTAAAAATCTTTACCATCACATGAGCAGTCATTACCGAAACTATTGCTGTAAGAAATGTGGAGCTGGTTACATTACTATAGCAGCGTTGAGGAAACACGGTAAGACGCACTATCAGGGCCACTTTCCGTGCGATTTCTGTGATAAATCTTACACTTCACTTACCAAGAAACGGAACCATGAAAAGGGTGTCCACACGGGTGGTTGGTTGAGGAACAAGTGCCCTCATTGTCCAGAAATATTTGTTAGTTACTACGACCGGAGCGAGCACCTGGTCAAAGTTCACAACGAGGCACCAGTGGTTTATCCTTGTAATGCCTGCAACAAGACGTACAAAAAGAAATTCGAACTCAATAGACATATAAAACACCATCATCTTCAACAGAGAAGCTTTTTATGTGATAAATGCAACGCAAAGTTCTTTTCAAAACGGGGTCTTGTGGATCACATGACGAGACACACGGGCTCCGAAATATGTTCGTGCGATATATGTGGGAAGGCCTTTTCGAGGATGAGAACCTTGAGAGAACATATGAGAATGCACGAGGATGATAAACGGTTCCAATGCGAAGTCTGTAAGAAGACCTTCATGCAAAAGAGCAGTTTGAAGAGTCACGTCAAACTCCACCAGGACGACCTGGATATATTTAAAGAGTTTGATGATGTAAAGCATCTTATAGATGACAGGGAGATGACACTCAAACAGATCGCTGCTGAGAACAAAGTGAGATCAATCGCCGTTaagttaaaaaatcaaatagttCGAACCCGAAAAAAAAGGAAACCGACTGTAATGGAAGAGAGTGCAGATCCAAATAATGTTACCTATCGGGAAAAACATCTGCGAGAGATTGAGAAGCAGGCACACAATCTCCTTACCCTTCTTAAATATTCTAACGCGACCCCCTTCAAGGATAGAAACGATGCAGGATATATGTGCGCGTATTGCTTTAAAAGTTTCCCAGATCCAAACAATCTAAGACAACACACTCGCTACGACCATATTTCAGAAAAACGTACATACAAAGCTTGTACAATCATAAGTAATTTTGTAGCATGTTTGGACATTGTCGATTTGAAATGTACTATTTGTGAGATGTCTATGGATAGCATTAAAGTTTTGAGCGAGCATCTAGTCGAAGAGCACGATAAGACATACTATAAAAGTGTTCGTGATTATTTTCAACCGTTCAAGCTTACTAAGGAGCAGCAGATACAGTGCTGTCTGTGCAACAAAAGCTACCACAACATGAGGTTGTTAATGcaacatatgaatatacattttcGTAATTTTATCTGTATGACTTGCGGTGCAGGATTTGTGAACAAGTATCGGTTGAGCAGGCACGAGAAATCTCACTCGAAGAAGAAGTCTGTCTTTGCCTGTCGACATTGTGGACAGGTTTTCGATGCTGAATCGAAGAAGAAAACCCATGTTAACACAGAGCATAAAGGCATCGAAGGGCACAGTATATGCCAAATTTGTAAGGCGAGATTCAAAAATTATTACCAGAAAACGAGGCATATGATGCAAGTGCACAAGAAGGAGGGGATTAAGTGTGACATGTGTGAGAAAAGATTTAACTTAAATGCAAATCTGATGCTGCACATGAGGGGTGTACATTTAAATGAGAGGCCCTACGAATGTACAGTATGCAGCATGGGTTTCTTAACCAATCGCCACATGCTCACACACTACATAGCCGCGCACAcaaatgaaagaaaatataaatgtgatATGTGTAGTAAGGCGTACGCTATTCAAAATAGTTTGAGGAAACATATTAATACCATTCACGGTGTCGAGCCTCAAACAACATTTATCGAAATCGTAATCAAACAAGAACCGATGTCTGATTCGGAACAACCTGAAGATTCTAAACCGGATACAGTTTTCCGAGTAGAACCGGATAAAGTTATAAAGAAAGATAAGGACCCAAAGAAAAGTGCTGCTGACCGGAAGTCTAAAAAGGATCAAATTATTGAAAtggaaaaacatttaaagaacATCAGCACTATTCTTCTTAACACAAACGCAACTCCGATAAGATATCACGATGGTGCGAATTACGTTTGTGCGCTTTGTCCGGAAACATACCCTATGCCCTCTGATCTTAAAGTTCACGTTTTAGAGGAGCATGACGAAATAGACAAAACTTCTTTCATGGAAGGTCACAGACTGACTTCTTATGTGGTGAAGTTAGACATAACGAATTTGCGTTGTCTTCTCTGCCACAACGATATCGAAAGTTTCGATCCGCTCTTCGAACATCTCAAATCGGTTCACGGGAAGGAAATGCACACGGATATACCAAACCACATTTTACCTTTCCGGTTCGTTGGTAACGGTTTTTATTGTGTTGTCTGTCCCAAGTCTTTTGAACATTTTAAACTAGTCCAGGAACATATGACTGTGCATTACAGAAATTATATTTGCGAAACATGCAACGCTCCTTTTGTCAATAAAAGAACTCTTCAAAATCACGCAAACAGACACAAGAAAGGTGACTTTCCCTGCAGTCAGTGTCCAAAAGTATTTGATACTAATCGAAAGAAATTGAATCACGAGAAATTTGTTCACGCCGGTGATTATAAGCGAAAAAAGTGTCCATATTGTCAGGAAAAGTTCACAAATTATGCTAAGAAACGATCTCATATGGTTAAGGAACATGGAGCGGAGCCGTTGTCTGTTAAATGTGATATTTGCAATAAGGTTTTTAGTACAAGAGCGAGATTAAGAGGACACACCCGCAGAGACCACATGGAGTGTCAACACGCCTGTAATAATTGTGAAATGAGGTTTTATTCCCCGTTAGAACTGGTCAAACACATGGTGAAACATTCTCCCCTTAAAGAATACCATTGTGATGTATGCAAAAAAGCGTACGCTAGGAAACACACTCTCCGCGAACATATGAAAATACACGCCAATATTCGGAACTTTAAGTGTGACATTTGTGAATTTACATTCGTTCAGAAGTGCAGTTGGAAATCACATATGcggaaaaaacataaaatacaagttAAATAA
Protein Sequence
MMQDNIGDGMCRCCASEGSFKDFQTTYHWMGVEEIYSDMLKDCFNISLVSSEAMNNGGICEVCVTQLRNAFNFKRQVQLTEEQFKKKVRESVLKSGTIKLEMSQEDVDSDNVASDNLSDADYEVPIKEEKQEDKPKKRQAKASTSKAKKPKTDGETSKRTDGEPKRKKKKKKSEVSATPERIEHRVNLTAILQFSNASPFRDKTMKGFSCLYCAKSFQGIDELRAHTAQQKEKDKINAMLDYKLSYNPIKLDITNLQCTVCHKDLKDLNELKEHLVSTHNKTIHKNIKDTILPFRLENGQNFMCVICSVVHISFKNLYHHMSSHYRNYCCKKCGAGYITIAALRKHGKTHYQGHFPCDFCDKSYTSLTKKRNHEKGVHTGGWLRNKCPHCPEIFVSYYDRSEHLVKVHNEAPVVYPCNACNKTYKKKFELNRHIKHHHLQQRSFLCDKCNAKFFSKRGLVDHMTRHTGSEICSCDICGKAFSRMRTLREHMRMHEDDKRFQCEVCKKTFMQKSSLKSHVKLHQDDLDIFKEFDDVKHLIDDREMTLKQIAAENKVRSIAVKLKNQIVRTRKKRKPTVMEESADPNNVTYREKHLREIEKQAHNLLTLLKYSNATPFKDRNDAGYMCAYCFKSFPDPNNLRQHTRYDHISEKRTYKACTIISNFVACLDIVDLKCTICEMSMDSIKVLSEHLVEEHDKTYYKSVRDYFQPFKLTKEQQIQCCLCNKSYHNMRLLMQHMNIHFRNFICMTCGAGFVNKYRLSRHEKSHSKKKSVFACRHCGQVFDAESKKKTHVNTEHKGIEGHSICQICKARFKNYYQKTRHMMQVHKKEGIKCDMCEKRFNLNANLMLHMRGVHLNERPYECTVCSMGFLTNRHMLTHYIAAHTNERKYKCDMCSKAYAIQNSLRKHINTIHGVEPQTTFIEIVIKQEPMSDSEQPEDSKPDTVFRVEPDKVIKKDKDPKKSAADRKSKKDQIIEMEKHLKNISTILLNTNATPIRYHDGANYVCALCPETYPMPSDLKVHVLEEHDEIDKTSFMEGHRLTSYVVKLDITNLRCLLCHNDIESFDPLFEHLKSVHGKEMHTDIPNHILPFRFVGNGFYCVVCPKSFEHFKLVQEHMTVHYRNYICETCNAPFVNKRTLQNHANRHKKGDFPCSQCPKVFDTNRKKLNHEKFVHAGDYKRKKCPYCQEKFTNYAKKRSHMVKEHGAEPLSVKCDICNKVFSTRARLRGHTRRDHMECQHACNNCEMRFYSPLELVKHMVKHSPLKEYHCDVCKKAYARKHTLREHMKIHANIRNFKCDICEFTFVQKCSWKSHMRKKHKIQVK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00958812;
90% Identity
-
80% Identity
-