Basic Information

Insect: Macrophya annulata
Gene Symbol: -
Assembly: GCA_963924015.1
Location: OZ001257.1:44023682-44028154[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.16 16 6.8 2.9 1 23 314 336 314 336 0.97

2 19 0.042 4.3 8.6 0.5 2 23 371 392 370 392 0.94

3 19 0.00027 0.028 15.5 1.4 1 23 439 461 439 461 0.96

4 19 0.052 5.5 8.3 0.4 2 23 465 486 464 486 0.95

5 19 2.6e-05 0.0027 18.7 1.8 2 23 532 553 531 553 0.97

6 19 0.00023 0.024 15.7 3.8 3 23 560 580 558 580 0.96

7 19 0.00063 0.066 14.3 0.8 1 21 586 606 586 610 0.92

8 19 0.00035 0.037 15.1 2.5 1 23 668 690 668 690 0.97

9 19 0.00064 0.066 14.3 4.5 1 23 721 743 721 743 0.96

10 19 0.0003 0.031 15.4 0.7 1 20 748 767 748 769 0.94

11 19 0.00051 0.053 14.6 0.5 2 23 780 801 780 801 0.97

12 19 1.4e-05 0.0014 19.6 0.7 2 23 840 861 839 861 0.97

13 19 2.8e-05 0.0029 18.6 1.6 1 23 866 888 866 888 0.95

14 19 9.5e-05 0.0099 16.9 1.5 1 23 894 916 894 916 0.98

15 19 4.9e-06 0.00051 21.0 0.4 1 23 932 954 932 954 0.95

16 19 4e-07 4.2e-05 24.4 0.6 1 23 960 982 960 982 0.99

17 19 4.3e-05 0.0045 18.0 0.2 1 23 988 1010 988 1010 0.97

18 19 0.00016 0.017 16.2 4.1 1 23 1016 1038 1016 1038 0.96

19 19 0.011 1.2 10.4 0.4 1 20 1044 1063 1044 1065 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.16	16	6.8	2.9	1	23	314	336	314	336	0.97
2	19	0.042	4.3	8.6	0.5	2	23	371	392	370	392	0.94
3	19	0.00027	0.028	15.5	1.4	1	23	439	461	439	461	0.96
4	19	0.052	5.5	8.3	0.4	2	23	465	486	464	486	0.95
5	19	2.6e-05	0.0027	18.7	1.8	2	23	532	553	531	553	0.97
6	19	0.00023	0.024	15.7	3.8	3	23	560	580	558	580	0.96
7	19	0.00063	0.066	14.3	0.8	1	21	586	606	586	610	0.92
8	19	0.00035	0.037	15.1	2.5	1	23	668	690	668	690	0.97
9	19	0.00064	0.066	14.3	4.5	1	23	721	743	721	743	0.96
10	19	0.0003	0.031	15.4	0.7	1	20	748	767	748	769	0.94
11	19	0.00051	0.053	14.6	0.5	2	23	780	801	780	801	0.97
12	19	1.4e-05	0.0014	19.6	0.7	2	23	840	861	839	861	0.97
13	19	2.8e-05	0.0029	18.6	1.6	1	23	866	888	866	888	0.95
14	19	9.5e-05	0.0099	16.9	1.5	1	23	894	916	894	916	0.98
15	19	4.9e-06	0.00051	21.0	0.4	1	23	932	954	932	954	0.95
16	19	4e-07	4.2e-05	24.4	0.6	1	23	960	982	960	982	0.99
17	19	4.3e-05	0.0045	18.0	0.2	1	23	988	1010	988	1010	0.97
18	19	0.00016	0.017	16.2	4.1	1	23	1016	1038	1016	1038	0.96
19	19	0.011	1.2	10.4	0.4	1	20	1044	1063	1044	1065	0.89

Sequence Information

Coding Sequence: ATGGACGCCGAAGAGGTAAATACGTCGGAACCTCcgcaaaatgaagaaaatatatcaacgGTTGTTGAAATCTGTCGAGTGTGTTTACTCGAGGGTGTAGAAATGAGAGATCTTTATTTGGAAAATGATGTCGCATCATTATCAACAAAAGCCATGAGTTTTACGAACGCTAAGatGATACCAGGGGACGGTTTGCCAGGACAAGTGTGTGCCTCCTGCGCAGAGAAATTGGATTCCGCATATGAATTCAAGCTTCAAGTTGAGCACGCCGATGGGATCCTGAGAGAGAGATATGTGTCGTTGAGTATAAAAGAAGAGTTATTTTTCAACGAGGTCGAAGTGGATTTGGAAACAAATCAAAACAGCGAACAAAATACGGAACAGTTATCAGAAACCCACATCCAGCTAAACACAGAGTCGGATCAAGAAGACCAAATAGATGGGGAAATGGAATCTTCGTTATTAAAAGACAATCTAGCACTTTTGCAGGTTGAAAAATTGGCAAAAGCTGAACAGGAGGGTCTGGAAATGGACGAAACTCTGCCGGAATCAATGGAAAACGTAAAAATAGATCCTGGTAGCATTGTTGCCCAAGAGCACGGGTATGGAGTGCAGCAAAAGTCTTTCAAAGAGGAAGAATTGCCTGCGGTAGAAACTTCCAACAATCAAGAGGCCATGGATTATGAAGAGGAGAGGGAAGGCGTTCAAcaagaaggaaaaaagaataggCAAAGTTCAGAACAGAAATTGGTAATTGAAAATGTGGAGAGTCTGGCTTCTGAACAATCGTCACAAATTGAAATTCGTAAAAGTAAACGCAAGTCTGCTCGAAGAGCACCAATCCTTGATCATGACTCTGACGAAGATaattactttgaaaatttgaatttgagcTCTCGGCTAAAACAGAGCCAGCCAGATAAGGCTGAGAAAGTTTATTACATGTGCTATATTTGTGACAAACATTTTTTGGCTAAGGGTGTGTTGAAAGAACATATGCACTCCCATGAGGAAGTTAGGAAAGTAATGTCTCTTGTAAAGGTGCCTGAAAAGAGTACCAAAGTTGCGCCGTCTCCGATAAAGCATTCTCCATCTGGAAAGCAGCCCAACAAATGTCCTTACTGCGGAAAAGAATATTTGTACATAATTTCGTACAACAAACACCTTAAGCAGCACGAAAATgacaaagaagaaacaaaGGTGGAGCCAATGCCATTGGAAGTCTCTTTCCACGAGGACGATAACACTTTGGATTTTGATAACTACGATAATAGTTACGATTCTGATCCAGATTGTAACGAAGAGAGCGAAGAACACGCTTGTGAAAAGTGCGAAGCAGTATTTAACAGCAAAAAATCACTCGACAAACACATGATTAAACACGAAATTCTCAAATGCAGTGTCTGCGAAGAAGAATTTGAGGGATTAGAGACATTCAAAAATCACCGGTCTCAACACGTTGCCGAGGGTGTACTGACGGAAGAAGATCTAAAAGAAGACATAAAACAAGTTGTTCAATTGCAAGAAAGTACAGAAGCGGATGAGGCGGTTCAAGCGCGTAGAAAAACTAGAAATTCCGAGACAAAAGGACTTCGATGTCCTAAATGTCCAATGGTATATTCTCACAAAAAGTCTTTATCAAGGCATCTTGAAACTCACAAGGGAACAAAATATGGATGTAAATCTTGCAGCCAGCAATTCACTCGTAAAGATCATCTCAGAAGACACATGGAACAGCATGGTAGAATGAAATCCTTCAAGTGTACCCAATGCAACAAGACCTTTGGTAATGAATTGACTCTGCGAAATCATCTGATAGCAACTAATCACAAGACTATTATTCGCGGGGAAGAATATGATCCTAATAAACGTCTGAAACGCGTAGCTGCAAAAGAGGCACAAAAGATTATCGACAAAATTAAAACTGAGGATAACGCAGATGATATAGATAGCAGTGACGGGGAAGAAAAaccacagaaaaaaatatacgagaaaaaagaatacGAATGTGCAACTTGCAACAGAAAATGTGCCTCTAAACAGTCTTTGACTAAACATATGGAACTACATATTAAAGATGAAAAGGGGGACAAGGAAATGAACCGTGGCTCAGATGACGACTCTGATTTTGACGGCGGTTTAGACTGGCCTATGGACAATCACGAATGTTTGACTTGCAAGAAGAGATATAGTACTAAAAAATCTTTGCTAAGGCATCAACTGCTGCACGAAGAACCTAACTTTGAATGCGATATTTGTAATGTAAAGTTTTATCGCAAGGACAAGCTAAAAGCACACTATGACAAATGTTCGGAAAAGAACCCTGACCAAGTTAGAAAGTGTAATATTTGCGGAGACAGCTTCGAAAACAACGATATGCTGAAGGAACACAGAGCAAAACATGTTACGGAGGGGATTTTAACCGAAGAAGATTTACGAGACATTGAACCACAAGTGGAGGAGAGAAAACCtggtgaaaaaataacaagaaaacgAAGAACTGATATCGTAGGACTGGAATGCACAGAGTGTAACAAACGATATACCTCTCGCAAGGGTTTGTTACGTCACATACAAGTTCACGAGGGTAAAAAATACCTCTGTGATATATgtccaaagaaattttacagGCGAGAACATCTAAAGATACACGTAGCCAAACACAATATGATTAAACCGTACAAATGCGATCGTTGTACTAAACGTTTTGCCAAAGAAGAACAGTTGATAAATCACTTATCTAAACACGatagaaattttaagaaaaacaaagaaactgaTAGTTCAAAAAGATTCTTGTGcgaaatttgttcaaaaagcTTTACTCAGTCGACTACACTTATCGCTCATTTGAGAGCTCACAACGGAATAAAACCCTACGTATGCGAAGTCTGTTCTCGACCCTTCACCACTAATGCTTATCTTAAAATGCACATGAGAACGCATACTCAAGAAAGACCTTACATCTGCCAGTATTGTTCTAGAGCCTTTGCCAGAGCGGATACTTTGGCAAATCATCTCACATCTCATACAGGGGAGGCTAAATATCACTGCAAATATtgtccaaaaaatttcagacgaTTGAAATCGTTGAAAGAACATGTGTTCATTCATACAGGTCAAAGACCTTACGCCTGTCCTACGTGCGATCGAAGGTTTAATAACAACGGAAGTAGATACGCACACAGCAAAAGGtgcaaacaaaatttattgcaaaatcAAAACAGGGGAcaaaattctaattctaatCAAGGTAGAATTCATGCCAGTAATCAGATGCAAACTATTAAACCACAGAGCGTTAaaactataactataactaGACAAGGGGATAGTGTTACTGCACAACAAGTTATGCATCATCAGGAAATTTTGATGCCTTTAATTTTGCCATTAACTGTTACGTTAGCTGATGTTGGAGAGGAAGTCATTCTGCCCGAgggtacaaaaatttttacaacttcGTAA
Protein Sequence: MDAEEVNTSEPPQNEENISTVVEICRVCLLEGVEMRDLYLENDVASLSTKAMSFTNAKMIPGDGLPGQVCASCAEKLDSAYEFKLQVEHADGILRERYVSLSIKEELFFNEVEVDLETNQNSEQNTEQLSETHIQLNTESDQEDQIDGEMESSLLKDNLALLQVEKLAKAEQEGLEMDETLPESMENVKIDPGSIVAQEHGYGVQQKSFKEEELPAVETSNNQEAMDYEEEREGVQQEGKKNRQSSEQKLVIENVESLASEQSSQIEIRKSKRKSARRAPILDHDSDEDNYFENLNLSSRLKQSQPDKAEKVYYMCYICDKHFLAKGVLKEHMHSHEEVRKVMSLVKVPEKSTKVAPSPIKHSPSGKQPNKCPYCGKEYLYIISYNKHLKQHENDKEETKVEPMPLEVSFHEDDNTLDFDNYDNSYDSDPDCNEESEEHACEKCEAVFNSKKSLDKHMIKHEILKCSVCEEEFEGLETFKNHRSQHVAEGVLTEEDLKEDIKQVVQLQESTEADEAVQARRKTRNSETKGLRCPKCPMVYSHKKSLSRHLETHKGTKYGCKSCSQQFTRKDHLRRHMEQHGRMKSFKCTQCNKTFGNELTLRNHLIATNHKTIIRGEEYDPNKRLKRVAAKEAQKIIDKIKTEDNADDIDSSDGEEKPQKKIYEKKEYECATCNRKCASKQSLTKHMELHIKDEKGDKEMNRGSDDDSDFDGGLDWPMDNHECLTCKKRYSTKKSLLRHQLLHEEPNFECDICNVKFYRKDKLKAHYDKCSEKNPDQVRKCNICGDSFENNDMLKEHRAKHVTEGILTEEDLRDIEPQVEERKPGEKITRKRRTDIVGLECTECNKRYTSRKGLLRHIQVHEGKKYLCDICPKKFYRREHLKIHVAKHNMIKPYKCDRCTKRFAKEEQLINHLSKHDRNFKKNKETDSSKRFLCEICSKSFTQSTTLIAHLRAHNGIKPYVCEVCSRPFTTNAYLKMHMRTHTQERPYICQYCSRAFARADTLANHLTSHTGEAKYHCKYCPKNFRRLKSLKEHVFIHTGQRPYACPTCDRRFNNNGSRYAHSKRCKQNLLQNQNRGQNSNSNQGRIHASNQMQTIKPQSVKTITITRQGDSVTAQQVMHHQEILMPLILPLTVTLADVGEEVILPEGTKIFTTS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00719614;
90% Identity: iTF_01414385;
80% Identity: -