Mann019579.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Macrophya annulata
Gene Symbol
KRBA2
Assembly
GCA_963924015.1
Location
OZ001261.1:20137394-20140322[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00046 0.048 14.8 4.1 2 23 400 421 399 421 0.97
2 15 0.0013 0.13 13.4 2.4 1 23 427 450 427 450 0.97
3 15 0.00011 0.012 16.7 0.8 2 23 525 546 524 546 0.97
4 15 7.4e-06 0.00077 20.4 2.3 1 23 552 574 552 574 0.98
5 15 0.00023 0.024 15.7 0.3 1 23 580 602 580 602 0.98
6 15 1.3e-06 0.00013 22.8 1.4 1 23 618 640 618 640 0.98
7 15 8.4e-06 0.00087 20.3 1.2 3 23 648 668 646 668 0.98
8 15 1.5e-05 0.0015 19.5 2.2 1 23 674 696 674 696 0.98
9 15 0.001 0.11 13.7 0.2 1 23 702 724 702 724 0.99
10 15 2.3e-05 0.0024 18.8 0.2 1 23 730 753 730 753 0.92
11 15 3.8e-05 0.0039 18.2 1.5 1 23 759 781 759 781 0.98
12 15 9.9e-05 0.01 16.9 4.6 1 23 787 809 787 809 0.98
13 15 7.6e-06 0.00079 20.4 0.2 1 23 815 838 815 838 0.96
14 15 1.7e-05 0.0018 19.3 0.9 1 23 844 866 844 866 0.96
15 15 4.5e-06 0.00047 21.1 4.5 1 23 872 894 872 894 0.99

Sequence Information

Coding Sequence
ATGGACAACAAATGGTTAGACAACAAAGTTACTACAGTAAATAGCGTAAATACTGCTTCAACAAACAGAATTGAATCTCATTTTGTATCTGTGAAACAAGAGGCAGAGTTTATCAATTATAACTTATGCTTGGAATCTGCTGTAACGCAAACTAATTCAAATGATTCTTTGATCAAGcagaagaataatgaaaataatcaaccTATACCATTAGCTAGCAACAAAACTGATATTGTTAGTTCAGATTCTGAGACTATGAATCATATTGTTGAAGCCGAGTCTAACCAAGGGGAAGAAAATGAGGATTACATATCTGAGCGGATAAATCCTCGATGTCAAGTTGACATTATTGATATGATAAATGATCAATATATGGATAACAAGTTCATCCTTGTTTACGaagatcaaaattcaaaatttgttatacTACGTCCTGTGAGAAGTAAAGAAGCAAAACATGTTGCGGCtgaattatttgatatatttgcAATCATCGGAGCTCCTAGGGTATTGCAGAGTAAAAACGGCAGAGATTTTGCTAATGAAATTGTCCATGAATTAAGATTGCTATGGGCAGATCTTGTGATAGTATATGGTGATGCTGTGATCTCTTCTACAAGTATTGAACGAGACTTTAAACAGCTTTTGAAAACCTGGCTTATTGATAATCCAGGTAAAACATGGTGCGAAGGACTTAGGTTTGTTCAAATCAATGAAAACAGAACGTTTCGTGCTGAAATTGACAAGACCCCACACGAATTTGTATTCACAAACAATGATAACAATGAACTCAGAACATTATCTATCCCAAAAGAAGCTATGAACACAATATGGTGCGAGGAAGATTggcaaaaattaatgaaaaatctcaAGGAAAGGGGCCAAACAAACAATGCAACTTCAAATAAAGAATTGTTTGATAACAACTGCAGTGAAAAAGGAATAAACAGTGATTCAGTTGATCAGATTGATGAGGATCCCCCCATCAAAGAAGATGGTAGGAATCGAGATGCTACTGAATTTGAGAATCAAACCAGACGATCATCGATCAATCGGGAAAATTCTAGTGgatttaaatttgtaaatgtTAAGAACGAAAGCCCTTTGAATATCACACAAGTAGAAGAATCACAATCAGAAACTGAGGCGAATGAAAATTGTCATACTAAAACAAGACCacgtaataaatatcaacTGAAGTGTAAGATCTGCCAGAAAAGATACATGAAGTTAGGACATCTGAAAAATCACCTTAAATCACACACAAAAGCTAATGGTTTCGACTGTACAATTTGTTCCAAAAAGTTCCGACTCTTGACTGTATATGAAAAGCACATGCGTCGTTTTCATAGCTCTGATAAAACTACTTCAAATATTAAACAGGGTCTTGAAAGTGATATAGAAGATAATTTAAAGCTTAAAAGACTCGTCGATGTTGAGCTGAAAACTGAAGAAACTAACTCACTATGTAACAAAGTAGTAAACAAAGTTGGAAGACGTTTATCTCGTCCAGgtggtaaaaaaatatcaaaagaaaatCGAGCCACTAGATTAAATGGCACTCCTTTGTTAGAGTGTAGTTATTGCCAGCAAAAATTTGACTTTCCAAGCGTTTTGAAAAGGCACGTAAGATCGCACACTAACGAAAGACCGTACGTTTGTCAGATATGCAATAAGAGCTTCAAACAGCTAGGACATTTGAGTCAACATTCGTTAACTCATACAGACTATCGTTCCTTTCAGTGTGCAACATGTGGGATAAAGTTCGAATCATTAGATAGTTTGAAAATCCATTCACAGTCCCATCGAGGTGACACTGTAATGTATAGACCAAAAGAAGTATATCGTCTGTTCGAATGTGATAATTGCAAAAAAGTATTTACTACTAAAAGCGTACTGGAAAGGCACATTTTTACTCACACCCATGAACGTcaatttggttgtaaagtatGTGGTAAAAGATTTAAGCAGGCAGGTCACGTAAAATCTCATATGCTTGTACACACAGGGGAACGAAAGTTTGAATGTAAAGTCTGTTCCAAGAGATTTAGTCTTTCTAATTCTCTAAAAaaacacatgtacatacacaatGGTGAGAAACCTTATCAATGCGATGTATGCGGGGCTCGTTTTCTTGAGAAACGAAACTTGAATGGTCATTTAATGACTCATACAAACGAACGACctttttcttgtaatatttgtGGCAAGAGATATACTCTTGCCGATACTTTAAGACGTCATGTTAGTGCAGCTCATGAGGATGGCAGAACATATCAGTGCGAGATTTGCGCTAAGATGTTTAAACAACTGGCGCACTTATACGTGCATAAAAAGGTTCACACAGATGAAAGACCCTATCAATGTCACCtttgcgataaaaattttaagcatAAGAATGTTCTAAAATCACATTTGGCTATACATGCTAACTTGAGACCCTTTGAATGCGATGTTTGCAAAGCAACATTTGTTAGGAAAACTAATCTCCAAACGCATATAGCTTCTGCTCACATGAATGAGCGCCCATATGTTTGTACCATTTGCAACAAACGATTTAAACAAGTCAGCCATTTGAATGGTCATGTTGTTGTACACAGTAATTCAATGCCATATCAGTGTGACTTTTGCGATCGACGTTGCAACAGATTGGATAACTTGAAAAAGCATATGCGATTGCATAcgaaaagtaaagaataa
Protein Sequence
MDNKWLDNKVTTVNSVNTASTNRIESHFVSVKQEAEFINYNLCLESAVTQTNSNDSLIKQKNNENNQPIPLASNKTDIVSSDSETMNHIVEAESNQGEENEDYISERINPRCQVDIIDMINDQYMDNKFILVYEDQNSKFVILRPVRSKEAKHVAAELFDIFAIIGAPRVLQSKNGRDFANEIVHELRLLWADLVIVYGDAVISSTSIERDFKQLLKTWLIDNPGKTWCEGLRFVQINENRTFRAEIDKTPHEFVFTNNDNNELRTLSIPKEAMNTIWCEEDWQKLMKNLKERGQTNNATSNKELFDNNCSEKGINSDSVDQIDEDPPIKEDGRNRDATEFENQTRRSSINRENSSGFKFVNVKNESPLNITQVEESQSETEANENCHTKTRPRNKYQLKCKICQKRYMKLGHLKNHLKSHTKANGFDCTICSKKFRLLTVYEKHMRRFHSSDKTTSNIKQGLESDIEDNLKLKRLVDVELKTEETNSLCNKVVNKVGRRLSRPGGKKISKENRATRLNGTPLLECSYCQQKFDFPSVLKRHVRSHTNERPYVCQICNKSFKQLGHLSQHSLTHTDYRSFQCATCGIKFESLDSLKIHSQSHRGDTVMYRPKEVYRLFECDNCKKVFTTKSVLERHIFTHTHERQFGCKVCGKRFKQAGHVKSHMLVHTGERKFECKVCSKRFSLSNSLKKHMYIHNGEKPYQCDVCGARFLEKRNLNGHLMTHTNERPFSCNICGKRYTLADTLRRHVSAAHEDGRTYQCEICAKMFKQLAHLYVHKKVHTDERPYQCHLCDKNFKHKNVLKSHLAIHANLRPFECDVCKATFVRKTNLQTHIASAHMNERPYVCTICNKRFKQVSHLNGHVVVHSNSMPYQCDFCDRRCNRLDNLKKHMRLHTKSKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01200365;
90% Identity
iTF_00938930;
80% Identity
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