Malb019219.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Macrophya alboannulata
Gene Symbol
KRBA2
Assembly
GCA_949628255.1
Location
OX451209.1:19447354-19450289[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00045 0.057 14.8 4.1 2 23 394 415 393 415 0.97
2 15 0.0013 0.16 13.4 2.4 1 23 421 444 421 444 0.97
3 15 0.00011 0.014 16.7 0.8 2 23 519 540 518 540 0.97
4 15 7.2e-06 0.00091 20.4 2.3 1 23 546 568 546 568 0.98
5 15 0.00023 0.029 15.7 0.3 1 23 574 596 574 596 0.98
6 15 1.2e-06 0.00015 22.8 1.4 1 23 612 634 612 634 0.98
7 15 8.1e-06 0.001 20.3 1.2 3 23 642 662 640 662 0.98
8 15 1.4e-05 0.0018 19.5 2.2 1 23 668 690 668 690 0.98
9 15 0.00099 0.13 13.7 0.2 1 23 696 718 696 718 0.99
10 15 2.3e-05 0.0029 18.9 0.2 1 23 724 747 724 747 0.92
11 15 3.7e-05 0.0046 18.2 1.5 1 23 753 775 753 775 0.98
12 15 9.6e-05 0.012 16.9 4.6 1 23 781 803 781 803 0.98
13 15 7.3e-06 0.00093 20.4 0.2 1 23 809 832 809 832 0.96
14 15 1.7e-05 0.0021 19.3 0.9 1 23 838 860 838 860 0.96
15 15 4.3e-06 0.00055 21.1 4.5 1 23 866 888 866 888 0.99

Sequence Information

Coding Sequence
ATGGACAACAAATGGCTAGAAAACAAAGTTACTATAGTAAATAGCATAAATTCTATTTCAACAAACAGAATTGAATCTCATTTTGTATCTGTGAAACAAGAGACAGAGTTTATCAACGATAACTTATGCCCGGAATCTGCTGTAACGCAAactaattcaaataattcttcGATCAAGCagaagaataatgaaaataatcaactTACACCATTAATTGTTAGTTCAGATTCTGAGACTATGAATCATATTGTTGAAGTCGAGTCTAACCAAGAGGAAGAGAATGAGGATTACATACCTGAGAGGATAAATCCTCGATGTCAAGTTGATGTTATTGATATGATAAATgatgaatatatgaataacaaGTTCATCCTTGTTTACGAAGATCAAAACTCAAAATTTGTTATACTACGTCCGTTGAGAAGTAAACATGCGAAAGATGTTGCAGCTGAattatttgatatattttcaatcatcGGTGCTCCTAAAGTATTGCAGAGTAAAAACGGCAGAGTTTTTGCTAGCGAAATTGTCCATGAATTAAGATTGCTGTGGTCAGATCTTGTAATAGTATACGGCGATGCTGTGACTTCTTCTACAAGTATTGAACGAGACTTTAAACAGCTATTGAAAACCTGGCTCATTGATAATCCAGGTAAAACATGGTGCGAAGGACTTCGGTTTGTTCAAATCAACGAAAATAGAACGTTTCGTTCCGAGCTTGATAAAACTCCGCACGAATTGGTTTTcacaaataatgataatgacgaACTCAAAACAGTATCTATTCCAAAAGAAGCTATGAACACAATATGGTGCGAGGAAGACTGGCAAAAACTAATGAAGAATCAAAAGGAAAAGGACCAAACAAACAATGAAACTTCAAACAAAGAATTGTTCGATAATAACTACAGCGAAAAAGGCATAAACAGTGATTCAGTCGATCAGATTGATGAGGATcTCCCCATCAAAGAAGATGACAGCAATCGACACGTTACTGAATTTGAGAATCAAACCGGACGATCATCGATTAATCGGGAAAATACTAGTGGATTTAAATTTGTGAATGTTAAGAACGAAAGCCCTTTGAATATTACACAAATGGAAGAATCACAATCAGAAACTGAAGCGAATGAAAATTGTCATACTAAAACAAGACAACGTGATAAGTATCAGCTGAAGTGTAAGATCTGCCAGAAAAGATACATGAAGTTAGGACATCTGAAAAATCACCTTAAATCACACACAAAAGCTAACGGTTTCGACTGTacaatttgctccaaaaagtTCCGACTCTTGACTGTTTATGAAAAGCACATGCGTCGCTTTCATAGCTCTGATAAAAGTACTTCCAATGTTAAACAGGGTCTTGAAAGTGATACAGAAGATAATTTGAAGCTTAAAAGACTGATCGATGTTGAGCTGAAAACTGAAGATACTAACTCACTACCTAAAAAAGTAGTGAACAAAGTTGGAAGACGTTTATCTCGTCCAGGTGGTAAAAAACTATCAAAAGAAAATCGGTCCACTAGATTAAATGGCGCTCCTTTGTTAGAGTGTAGTTATTGCCAGCAAAAATTCGACTTTCCAAGCGTTTTAAAAAGGCACGTAAGATCGCACACTAACGAAAGACCATATGTTTGTCAGATATGTAACAAGAGCTTTAAACAGTTAGGACATTTGAGTCAACATTCGTTAACGCATACAGACTATCGTTCCTTCCAGTGCGCAACATGTGGGATAAAGTTCGAATCATTAGACAGTTTGAAAATCCATTCACAGTCCCATCGAGGTGACACTGTAATGTATAGACCAAAAGAAGTATATCGTTTGTTCGAATGTGATAATTGCAAAAAAGTATTTACTACTAAAAGCGTACTGGAAAGGCACATTTTTACTCACACCCACGAACGTCAATTTGGTTGTAAAGTATGTGGTAAAAGATTTAAGCAGGCAGGTCACGTAAAATCTCATATGCTGGTACATACGGGGGAACGAAAGTTTGAATGTAAGGTCTGCTCCAAGAGATTCAGCCTTTCTAATTCTCtaaaaaaacacatgtacatacacaatGGTGAGAAACCTTATCAATGCGATGTATGCGGGGCTCGTTTTCTTGAGAAACGAAACTTGAATGGCCATTTAATGACCCATACAAACGAACGACCTTTTTCTTGTAATATTTGTGGCAAAAGATATACTCTTGCCGATACTCTAAGACGTCATGTTAGCGCAGCTCATGAGGATGGCAGAACATATCAGTGCGAGATTTGCGCTAAGATGTTTAAACAACTGGCCCACTTATACGTGCATAAAAAGGTTCACACAGATGAGAGACCTTATCAATGTCACCtttgcgataaaaattttaagcataAGAATGTTCTAAAATCGCATTTGGCAATACATGCTAACTTAAGACCCTTTGAATGCGATGTTTGTAAAGCAACATTTGTAAGGAAAACTAATCTCCAAACGCATATAGCTTCTGCTCACATGAATGAGCGTCCATATGTTTGTACCATTTGTAACAAACGATTTAAACAAGTTAGCCATTTGAATGGTCATGTTGTTGTACACAGTAATTCAATGCCATATCAGTGTGACTTTTGCGATCGACGTTGCAACAGATTggataatttgaaaaagcaTATGCGACTGCACACGAAAAGTAAAGAATGA
Protein Sequence
MDNKWLENKVTIVNSINSISTNRIESHFVSVKQETEFINDNLCPESAVTQTNSNNSSIKQKNNENNQLTPLIVSSDSETMNHIVEVESNQEEENEDYIPERINPRCQVDVIDMINDEYMNNKFILVYEDQNSKFVILRPLRSKHAKDVAAELFDIFSIIGAPKVLQSKNGRVFASEIVHELRLLWSDLVIVYGDAVTSSTSIERDFKQLLKTWLIDNPGKTWCEGLRFVQINENRTFRSELDKTPHELVFTNNDNDELKTVSIPKEAMNTIWCEEDWQKLMKNQKEKDQTNNETSNKELFDNNYSEKGINSDSVDQIDEDLPIKEDDSNRHVTEFENQTGRSSINRENTSGFKFVNVKNESPLNITQMEESQSETEANENCHTKTRQRDKYQLKCKICQKRYMKLGHLKNHLKSHTKANGFDCTICSKKFRLLTVYEKHMRRFHSSDKSTSNVKQGLESDTEDNLKLKRLIDVELKTEDTNSLPKKVVNKVGRRLSRPGGKKLSKENRSTRLNGAPLLECSYCQQKFDFPSVLKRHVRSHTNERPYVCQICNKSFKQLGHLSQHSLTHTDYRSFQCATCGIKFESLDSLKIHSQSHRGDTVMYRPKEVYRLFECDNCKKVFTTKSVLERHIFTHTHERQFGCKVCGKRFKQAGHVKSHMLVHTGERKFECKVCSKRFSLSNSLKKHMYIHNGEKPYQCDVCGARFLEKRNLNGHLMTHTNERPFSCNICGKRYTLADTLRRHVSAAHEDGRTYQCEICAKMFKQLAHLYVHKKVHTDERPYQCHLCDKNFKHKNVLKSHLAIHANLRPFECDVCKATFVRKTNLQTHIASAHMNERPYVCTICNKRFKQVSHLNGHVVVHSNSMPYQCDFCDRRCNRLDNLKKHMRLHTKSKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01200365;
90% Identity
iTF_00939791;
80% Identity
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