Mann006962.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Macrophya annulata
Gene Symbol
Ipp
Assembly
GCA_963924015.1
Location
OZ001258.1:16062610-16073199[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.3e-29 5.4e-27 94.8 0.0 1 109 90 196 90 197 0.94

Sequence Information

Coding Sequence
ATGCGtttgaaaggaaaaaacaacaacaaatctTTCAACAGCGTCTATAAGGTGCTGTCCCGTATATGTCGAGCTGTTGACAAAGGGCAACTCGATGGTTTCATGGCTGATGGTGCGGTGCCTCCACTAAAAAGTGGCCACAACTCTAAAACTATGGGATTTGCGGCACAACCGGTCAAACAGTCGGCACAACCGGTTAAACAGGCCGCTGATGCGTCTAGTACAGTATACGCAGTCGGACAATATGCGCCAAAAGTCTTGAAAAATCTAAATGCTCAAAGAATGAAGAATCAATTCAGCGATGTTGGCTTAGTTGCCGGCGGAAGCGTTATTAGAGCTCATCGATCAGTTCTGGCTGCTGGCAGTGCTTATTTCAACGCAATGTTTACTGGCGGTCTAGTCGAAGAGCAGCAAGAATTGGTAGAGATTCACTCCATCTCTGCTAAAATTCTTTCGCTTCTtgtagattttatatatactggTGATGTAGAAATTACTCAGGATAACGTTCAAGAATTATTTGCCGCTGCCGACATGCTGGAATTAGATGAGGTTGTGTCGGGTTGTATTACTTATCTGCAACAACAACTGCACTCTAGCAATGCTCTTGGAATTTACAGATTTGCGGAAGCACATAACACGCCGAACCTGCTGATGACTGCCTTacgttttattgaaattaattttcctcAAGTATCACAGGAAGAGGAATTCCTAGATCTTCCAAAAGAACAACTAGTGAAATTCATATCTAgtgaatatattcatattgaCACCGAATTTCAGGTATTTCAAGCAGCGCATAATTGGATTGTTCATGATATACCAGCAAGACGTTGCTATGTATTTGAGGTGCTACGTTATGTTAGGCTTCGACTCTGTTCAGTAGCACGTTTGGAAAGAGTTATCTTAGACAGTAAAGACGCAAGCCTAATTGTAGCTCTTAGATCGGTTCTGAAAGATTTAATAACGAACAAAGGATGTCTGGTGCCGCTTCATGAGCAACCAAGACTTTGCGcaaagaaaaacattttagTAATTGGTGGTTCAAAGCGAGAGCCGTCAGCTGATAGTTGGGGAAGAGCTGCAGAAAGTACTTATGAAACTATTGAAAAATACGACACATTTACGGGagaatGGAGCGAAGTAGCACCAATTGGTATCGGCAGAATATTGCCTGGCGTAGCATTACTAGATGGCAAAGTGTATGTCGTCGGTGGTGAACTTGAATCCTGTATAATTGCAAACGGTGAATGTTACGATCCTCGCGATAATGTATGGACATCCATTGCCTGCATGATAGAACCACGTTGTGAATTTGGTCTTTGCGCCATAGATAATAGTTTATACGCATTTGGTGGATGGGTTGGCGAAGACATTGGTGGTTCTATCGAGATATACGATCCAATAGCTGATTCTTGGGCTCTGGATGGAGAACTTCCTGAACCCCGATTTAGTATGGGTGTTGTCGCTTAcgaagGATTGATATACGTCGTTGGTGGATGTACCCACAACAGCAGACATCGCCAAGATGTAATGGGCTATAATCCAGTGACAAGAGAATGGACATATCTGGCTCCTATGCTCACTCCTCGCATGCAAATGGGTATTGCTATACTTGATGGTTACATTTACGTTGttggaggaataaataaaaaccaggAAGTCTTGACATCTGTGGAAAgatattcatttgaaaagGATAAATGGAGTACTGTTGCTCCCATGAATGTGGGACGAGCATATCCTGCCGTTGCTGCAGCCGATGGTCGTTTGTACGTTATAGGTGGTGATCAATCGCAGGAGATAAACTTTTATCGAACTCAGATAACAATCTCTACAGTAGAATGTTACGATCCGCATTTGAACGCATGGCATGAATGTGCTTCTCTGCCGACAAGTAGGGGTGAGGCTGCAGCCATAATTGCGCCCTTCTGA
Protein Sequence
MRLKGKNNNKSFNSVYKVLSRICRAVDKGQLDGFMADGAVPPLKSGHNSKTMGFAAQPVKQSAQPVKQAADASSTVYAVGQYAPKVLKNLNAQRMKNQFSDVGLVAGGSVIRAHRSVLAAGSAYFNAMFTGGLVEEQQELVEIHSISAKILSLLVDFIYTGDVEITQDNVQELFAAADMLELDEVVSGCITYLQQQLHSSNALGIYRFAEAHNTPNLLMTALRFIEINFPQVSQEEEFLDLPKEQLVKFISSEYIHIDTEFQVFQAAHNWIVHDIPARRCYVFEVLRYVRLRLCSVARLERVILDSKDASLIVALRSVLKDLITNKGCLVPLHEQPRLCAKKNILVIGGSKREPSADSWGRAAESTYETIEKYDTFTGEWSEVAPIGIGRILPGVALLDGKVYVVGGELESCIIANGECYDPRDNVWTSIACMIEPRCEFGLCAIDNSLYAFGGWVGEDIGGSIEIYDPIADSWALDGELPEPRFSMGVVAYEGLIYVVGGCTHNSRHRQDVMGYNPVTREWTYLAPMLTPRMQMGIAILDGYIYVVGGINKNQEVLTSVERYSFEKDKWSTVAPMNVGRAYPAVAAADGRLYVIGGDQSQEINFYRTQITISTVECYDPHLNAWHECASLPTSRGEAAAIIAPF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01232467;
90% Identity
iTF_01303561; iTF_00938858; iTF_01414317; iTF_01411638; iTF_01413465; iTF_01412447; iTF_00060448; iTF_00174410; iTF_00175160; iTF_00175834; iTF_01200303; iTF_00159216; iTF_00719539; iTF_00718724; iTF_01048314; iTF_01049031;
80% Identity
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