Basic Information

Insect: Macrophya annulata
Gene Symbol: Hr39
Assembly: GCA_963924015.1
Location: OZ001259.1:19035774-19040601[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 4 2.8e+04 -10.4 16.3 68 164 197 294 148 393 0.62

2 4 4.8e-08 0.00034 20.8 0.0 1 21 492 512 492 517 0.92

3 4 0.11 7.8e+02 -0.2 2.7 88 146 549 601 524 621 0.49

4 4 2e-70 1.4e-66 226.3 0.4 200 408 619 822 607 822 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	4	2.8e+04	-10.4	16.3	68	164	197	294	148	393	0.62
2	4	4.8e-08	0.00034	20.8	0.0	1	21	492	512	492	517	0.92
3	4	0.11	7.8e+02	-0.2	2.7	88	146	549	601	524	621	0.49
4	4	2e-70	1.4e-66	226.3	0.4	200	408	619	822	607	822	0.96

Sequence Information

Coding Sequence: ATGTCGGAGCAGAACGGGCCCCCGGAGGGCCCAGGCTGGTGGCCTCCGGCCCAATCCTGGAAGTCGTCGTCGGCCCCTGCGAGACCAGAAGCCGGAAAAAACGTATCTGTGACCACCATCAACGTTCCACCAGCCCACGAAATGCACGatgGTAAAAATGTTAAGTATTTGGGCGGTCGGAACGGTGTGACGGTGTCCGTTGTGTCCGGATGCGGTACCGGAAATGAACCCGAAAATGACGGAGCTGACAGTGACGGTGAAGTAAGCAAGATCGACTTCCGGGGAGTAAATCTACGGACGAAGAAAAAGAGGGACGCGCCAGAAGGCCAGGAAAGCGATGCCTGTAGCACCGTTACAGAAGCGATGCTACAGCAACCAGAACGCCCTATGTCCTGGGAAGGAGAACTTTCCGATCAGGAAATGTCTTCGAATACAATTACTAATCAAGACCATGAAGAAACTTCAATGGAAGGTGTTCAAGTGTGTAGTGCGAGCCCAGGACCAGCGCACGCACCACAAGAACCCAAGTTCCCCATAAAACTTGAACCAGATTTCCGCTCAAGTCCAGCCCCGCCTTTAGGACCCCCCAATGAAACACTCCTCCCAAACACCCAACAAcaccaacagcagcaacaacaacaacacaaTATCGAAGGGCTTGAGCAAACCCAACAAAGTGATTTGCCATTACTTGTTGGAAAACTACTTGGTGGATATAACAATGCTACCCCTAATCACAGCCCAGTTCTTAATCCAAGACATCATCTGACTAAACATAGCCACACGAGATCACAGGTTCCATCACCTGATTCAGCGATACATTCAGCATACAGTGTATTTAGCTCCCCTACACAAAGCCCACATGCTGCTCGTCATTCAGCGCTTGGAGCTGGTAGCCCTGTGCCGTCTTCATCGTTGTCACTTTCGCGTCATAGTTTCAACAATTCCACATCTTCGCTTTCCTTGTCGCTATCACATTCGCTATCGCGAAATAACTCTGATGCATCCAGCAGCTGTTACAGCTATGGGTCTCTAAGTCCACCGACACATTCGCCCGTGCAACAACCAAGACACTCCCATTCCCATACTTCACATCCTCATCATCAGGTTGGAGCGCAGGGTAGCCCTTTGCATTTGCCAGTATCCCATCATTATTCAACAACAAATTCCGAGCTTTCCGAAGGCTTAAGCGAGGACCAGGAAGACTGTAAAATAGCACCAGCTACAGCGGGAATTTCCACTAGGCAGCAGCTGATTAATAGTCCCTGTCCAATTTGCGGTGACAAAATCAGCGGCTTTCATTACGGTATATTCTCGTGCGAATCATGCAAAGGATTTTTCAAGAGGACCgtacaaaacagaaaaaattacgTCTGCCTTAGAGGGGCGGGATGCTCGGTGACTGTAGCAACCCGAAAAAAGTGTCCCGCTTGTAGATTTGATAAATGTTTGAATATGGGAATGAAATTGGAAGCAATTAGAGAAGATAGAACTCGAGGAGGTAGAAGTACGTATCAGTGTAGTTACACGCTGCCAGCAAATTTGGTCGGCTGTAATTCTGGCGGATTACCTGGTGACAAAATGGCTGGTGGAACATGTAGCCCTGCACCTCCTGGATACGAACATCACCATTCGGCAAGGCATCATTCTAATCATTCGCATAAACTTCACGTAGTGCCGCAACTTTTGCAAGAAATTATGGACGTCGAACACTTGTGGCATTATAATGACAATGATAGAACTACAAGTGCTCaaagcagtagcagtagcagcaaaTCCGAACAGCCAAGGCCGAGCTCTACCGGACCACAAAACACCGAACATGACCAACACCCACCTAGTAATGCTAATAGTAATGCGAACCCTTCTCAGCATCCTGACTTTTTGTCTAACCTGTGCAATATCGCAGATCATAGGCtttataaaatcgttaaatgGTGCAAGAGCTTGCCcttatttaaaaacatttcaattgACGATCAAATTTGTCTACTTATCAATTCATGGTGCGAATTGTTGCTGTTCTCATGCTGCTTTAGAAGCGTCAATACTCCAGGAGAGATTCGTGTCTCACTTGGGAAGTCAATAACACTTGAACAAGCCAGACAGCTTGGTCTTGCTAGTTGCATCGAAAGAATGTTGGCTTTCACCAACAACCTCAGGCGATTGAGAGTCGACCAATACGAATACGTAGCAATGAAGgTCATTGTTCTGCTGACTTCTGACACAAGCGAGTTGAAAGAACCAGAAAAAGTTAGAGCATCTCAAGAAAAAGCACTTCAAGCATTACAGCAATATACAATTGCAATGTATCCAGAAATGCCAGCCAAATTTGGCGAACTGCTCCTCAGAATCCCAGACTTGCAGCGAACATGCCAAGCAGGGAAAGAGCTTCTCAGTGCAAAACGAGCTGAGGGTGAAGGCAGTtcgttcaatttattaatggAACTGCTCAGAGGGGACCACTGA
Protein Sequence: MSEQNGPPEGPGWWPPAQSWKSSSAPARPEAGKNVSVTTINVPPAHEMHDGKNVKYLGGRNGVTVSVVSGCGTGNEPENDGADSDGEVSKIDFRGVNLRTKKKRDAPEGQESDACSTVTEAMLQQPERPMSWEGELSDQEMSSNTITNQDHEETSMEGVQVCSASPGPAHAPQEPKFPIKLEPDFRSSPAPPLGPPNETLLPNTQQHQQQQQQQHNIEGLEQTQQSDLPLLVGKLLGGYNNATPNHSPVLNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAARHSALGAGSPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRHSHSHTSHPHHQVGAQGSPLHLPVSHHYSTTNSELSEGLSEDQEDCKIAPATAGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCSVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCSYTLPANLVGCNSGGLPGDKMAGGTCSPAPPGYEHHHSARHHSNHSHKLHVVPQLLQEIMDVEHLWHYNDNDRTTSAQSSSSSSKSEQPRPSSTGPQNTEHDQHPPSNANSNANPSQHPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVNTPGEIRVSLGKSITLEQARQLGLASCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIAMYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGSSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00174217;
90% Identity: iTF_00938835;
80% Identity: iTF_00939693; iTF_00939578;