Basic Information

Insect: Macrophya alboannulata
Gene Symbol: -
Assembly: GCA_949628255.1
Location: OX451206.1:22653575-22655404[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00064 0.081 14.3 0.6 1 23 81 103 81 103 0.96

2 14 0.54 69 5.1 3.2 1 20 191 210 191 213 0.93

3 14 0.0027 0.34 12.3 2.0 1 23 222 245 222 245 0.96

4 14 0.00041 0.051 14.9 1.0 1 23 263 285 263 285 0.97

5 14 0.12 15 7.2 3.2 2 23 296 318 295 318 0.94

6 14 2.8 3.6e+02 2.8 9.1 2 23 325 346 324 346 0.94

7 14 0.0073 0.92 11.0 3.1 1 23 355 378 355 378 0.97

8 14 0.067 8.5 7.9 1.9 1 23 395 418 395 418 0.95

9 14 1.5e-06 0.00019 22.5 1.3 1 23 424 447 424 447 0.96

10 14 0.015 1.9 10.0 0.8 3 23 454 475 452 475 0.94

11 14 0.00014 0.018 16.4 0.2 1 23 480 503 480 503 0.97

12 14 2.2e-08 2.8e-06 28.3 0.4 2 23 510 531 509 531 0.97

13 14 5.6e-08 7.1e-06 27.1 0.4 1 23 537 559 537 559 0.98

14 14 2e-07 2.5e-05 25.3 0.3 1 23 565 587 565 587 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00064	0.081	14.3	0.6	1	23	81	103	81	103	0.96
2	14	0.54	69	5.1	3.2	1	20	191	210	191	213	0.93
3	14	0.0027	0.34	12.3	2.0	1	23	222	245	222	245	0.96
4	14	0.00041	0.051	14.9	1.0	1	23	263	285	263	285	0.97
5	14	0.12	15	7.2	3.2	2	23	296	318	295	318	0.94
6	14	2.8	3.6e+02	2.8	9.1	2	23	325	346	324	346	0.94
7	14	0.0073	0.92	11.0	3.1	1	23	355	378	355	378	0.97
8	14	0.067	8.5	7.9	1.9	1	23	395	418	395	418	0.95
9	14	1.5e-06	0.00019	22.5	1.3	1	23	424	447	424	447	0.96
10	14	0.015	1.9	10.0	0.8	3	23	454	475	452	475	0.94
11	14	0.00014	0.018	16.4	0.2	1	23	480	503	480	503	0.97
12	14	2.2e-08	2.8e-06	28.3	0.4	2	23	510	531	509	531	0.97
13	14	5.6e-08	7.1e-06	27.1	0.4	1	23	537	559	537	559	0.98
14	14	2e-07	2.5e-05	25.3	0.3	1	23	565	587	565	587	0.98

Sequence Information

Coding Sequence: ATGGAACTGTGGCAGAGATCAAACCCAAAGGGGAAACCGTCCTATTCTCTGGTGCCTATCACCGGACGGAATTCGACGAGCAGAAGGAATTCTAAGGATGAACTGATACCGGCTAACGAGATCAAAGTCGAAATCAACGAGGAGACAGTCGGCACAAGGTGCCTCACGGAATCCACTGCCTGCGAGGAGAGACGGTGTCAAGAGTCTCTTGCTCACCTATGCCAAGTTATGATAGAATTTCATCCGTGCGATCAATGCGGGATAAAATTTCCCGTCGAGAATATGCTCAAAAGACACAAAATAAGACACACTAGGAAGTACGTTGCTTGGAAAAGGTACACGTCGGAGAGAAGAGGGATTATTCAGGAGCAGAAATGCGCCGTTTGCGATATTAAATTGGCTAAAAAAGATCGTCGTAATTCTCTTAACATATGGAGGCACAGAGTAGAGGAGAAAAACGTTCTCTATCTTTGTAGTTTTTGCGATTTTAAATGCCACAAAAGAATCACACTTACTTCCCACGTTACTAGGAAACACAAGACACGGGATTCTGAAAatcgttcaaaattttaccgCTGCGGCAGTTGCGATTACAAGTGTTTAAAAAAGGATAATTTCAATGCCCACATGTGGAGGCACAGGAGCGATGTAAAGGAGCCTAGCTTTCCCTGTAAGATGTGcgattttaagtcgaaaaaacGTAGTACATTAGCCTCTCACATTACAAGAAAACACAAGCTTAAGaaggaaggagaaaaaaaaatggaagaaaaggCCGAGGAGGAATATCGCTGCGACACGTGCGATTACAAGACTTTAAAGAAGGAGAATCTCCAGGCCCACATGAGAggacataaaaaaattatggaaaaagGTGTATCGCTGTCCTGCACCTCCTGCGATTTTAAGTGCAAGAATCGCGGGACGCTGGCCTCCCATGTTACAAGAAAACACAAAATCGCCGAAGAATGCAGCTGCAATGTCTGTGACTTTAAATGCTTCAAGAAAAGCACAATGTACTCTCACAAGCGAAGGCACAGGGCTGAGAGCGAAGGCAAGGTCTACAACTGTAACGAGTGTAACttcaaaacaataaaaaagacCTCCCTTTACTCTCACATAAAGAGAAAGCACAAAGTACAGGTCAAGACTGGCTCTGGTCTTGAACAGGTCACGGAATACTTTTACTGCAGTCAGTGTgagtacaaaaataaaaataagtacgAACTGAAGGTACACGTCGCCCGAAAACACACAGACGATTTCAAATTCTCCTGCGAGACTTGTGGCAAGAAATTCAAGGTCAAAGGCGATCTCACTAATCACATAAGGTTCAATCACAAGGAGGGACCTGTAATATGCGATGTATGCGGCAAGACCTGCTTAAACAGCAACTCTCTTTACGTTCATCAAAAGTTTGCTCATTACAAAGCCAAGTACGAGTGCGGGATTTGCAAACGGCGGCTTGTAACCCAGGAGAACTTGGACGATCACATGTTACGACAGCACGAAAAACGTGAGAACGTTGTGTGCGAGGAATGCGGAAAAACTTTTTCGCGTAACAGCCGGCTTAAAGTTCACATGAGAATTCACACAGGGGACAAACCCTACACTTGCAATATATGCGGAAAGTCATTCGCAAGACGAACAGCACTGAAACAACATCTTCTCATACATACGGGCATGAGACCCTACGTTTGCGATATTTGCGGTAAATCTTTTACACAAAAACCGGGACTCATCAGCCATCGGAAATCACATCCCGGATCCCATCCTCCCTTACCCAGGGTTCTCATTGATCATATACTCAACGACGTTATGAACAACTGA
Protein Sequence: MELWQRSNPKGKPSYSLVPITGRNSTSRRNSKDELIPANEIKVEINEETVGTRCLTESTACEERRCQESLAHLCQVMIEFHPCDQCGIKFPVENMLKRHKIRHTRKYVAWKRYTSERRGIIQEQKCAVCDIKLAKKDRRNSLNIWRHRVEEKNVLYLCSFCDFKCHKRITLTSHVTRKHKTRDSENRSKFYRCGSCDYKCLKKDNFNAHMWRHRSDVKEPSFPCKMCDFKSKKRSTLASHITRKHKLKKEGEKKMEEKAEEEYRCDTCDYKTLKKENLQAHMRGHKKIMEKGVSLSCTSCDFKCKNRGTLASHVTRKHKIAEECSCNVCDFKCFKKSTMYSHKRRHRAESEGKVYNCNECNFKTIKKTSLYSHIKRKHKVQVKTGSGLEQVTEYFYCSQCEYKNKNKYELKVHVARKHTDDFKFSCETCGKKFKVKGDLTNHIRFNHKEGPVICDVCGKTCLNSNSLYVHQKFAHYKAKYECGICKRRLVTQENLDDHMLRQHEKRENVVCEECGKTFSRNSRLKVHMRIHTGDKPYTCNICGKSFARRTALKQHLLIHTGMRPYVCDICGKSFTQKPGLISHRKSHPGSHPPLPRVLIDHILNDVMNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00939809; iTF_01303657; iTF_00060556; iTF_01411772; iTF_01414422;
90% Identity: iTF_00939809;
80% Identity: -