Basic Information

Gene Symbol
-
Assembly
GCA_951509405.1
Location
OX608049.1:37748038-37752455[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.0011 0.2 13.4 3.4 2 19 302 319 301 322 0.94
2 18 0.0089 1.7 10.5 1.5 3 23 335 355 334 355 0.89
3 18 0.22 42 6.1 0.2 3 23 364 385 363 385 0.94
4 18 0.029 5.5 8.9 1.0 1 23 391 413 391 413 0.92
5 18 0.00023 0.044 15.5 1.6 1 23 419 442 419 442 0.97
6 18 0.00035 0.065 14.9 2.9 1 23 448 470 448 470 0.99
7 18 5.8 1.1e+03 1.6 0.1 3 23 481 501 479 501 0.79
8 18 0.00075 0.14 13.9 0.3 1 23 517 539 517 539 0.96
9 18 0.38 71 5.4 3.8 1 23 544 566 544 566 0.95
10 18 0.0023 0.43 12.4 0.5 1 23 582 606 582 606 0.97
11 18 6e-05 0.011 17.3 0.4 2 23 611 633 610 633 0.96
12 18 0.015 2.8 9.8 0.3 1 23 638 661 638 661 0.96
13 18 0.0024 0.45 12.3 0.6 1 23 666 689 666 689 0.96
14 18 0.00047 0.087 14.5 0.0 2 23 693 715 692 715 0.96
15 18 0.044 8.3 8.3 3.1 1 23 721 744 721 744 0.94
16 18 0.0017 0.32 12.7 0.2 1 23 750 772 750 772 0.98
17 18 1.8e-06 0.00034 22.1 1.4 1 23 778 800 778 800 0.99
18 18 0.00075 0.14 13.9 0.1 1 23 806 831 806 831 0.97

Sequence Information

Coding Sequence
ATGGACTTGCCGAAATGCGTCAGATGCTTTTGCGATCTATTTGATGATTTTCAACTGATTTTCGATGACACCGGCCTCGAACTGGAACTCCAAAAACTGCtatcaatttgttttgataTGGACATTAAAATTCGACTAGGCGAAATTCAAGCGCTATGTGAAGATTGCCTAAATGAGCTAATTGATACTTACGATATAATTCAGAAGAACGAACAGGAAGGTGCAGGACCCTCGGGAAATCAAATTCTTagtacgaaaattaaaaatgaaaatgactCGCCTGAGCAAAATTCCGGCTCTGATGATTTTGGAAGTTTTTCTGACGAGGAGGAAATTATTCAGAAATCTTCGAGAAATCGAGACATTAAGGAGCGAAAAGATATAAAGGCTAAAGAATCTATGTTAAAAGATAAACATAATTTGAGACATAAAACCGTTAAGCAGGATACCCGAATTTCGAAGATTGTGGAGTTTGTGGAGGATGAAAATTCGCTAGAAGAAATTAAGAAGTCAGACGAGAACTATGATGTTAATGAATTGGATGATGAAACTTCCAATTTAGAAGTCACGGaaaaagaCAACGATGACTGCGAAGAATATAACCAGGTTGATTATTTGGATGATTTTGACgaggaaattgattttaatgaatataaaGGTCGAATTATTCAAAGCAAGTTCTCAGATGTTTGCTTTCCAGAGGAGATTAAATGTCGTTTGTGTGAAACTGGCATGAAGACCCACTTGGATTTGATGAGCCACACTGTGGAAATGCACTGCGTCGAGGAATTTGCATATCCTTGCATAGTCGACAGGGAATGTGAATCGGTGAGCTCTCAGGAGCACTTAACGCTTCACTTAGTATTCAAACACTATGATTTGGATTCATTGGCAATTTACTCCAAATGTCCAGAATGTGAAAAGCGTTTTAGCGACTTTTCCTCTTTCAACAAACACAGCTGTTATCAACTGCCGGGGAAACTATCTCGAACCAAAGTGGACTGTGATGAATGTGGAAAAGTGTTTACAACAAATaaaagATACCGCTTTCATCTCCAATTTCATCTTGAGAAGCGCCGTCCAAAGGCTTGTTTCGTTTGCGAGACGTTGTTTAGGGATGAGgatgaattttttgagcatGTAATGTACAACCATGAAAAGAGTCTGGATTTTGTGTGCATaagATGTGATCGTTATTATACATCTgctgaaacttttaaaaatcaccAAGAAAGCCACAAAAATGAGCGGAAATATGCCTGCAAATTGTGCCCTAAAACTTATATCTACAAGCATTTTTTGTCCGATCACATGataACCGATCATGATGCAAAAAGTGATTTCAAGTGCCACATTTGCGGCAAGTATTGGATTAACAagacttatttaaaaaatcatttattaacGCACAATAAGCCCAAACCAACTGAAGTTATTTGTTGCAATGAGTGCGGATTTGTGGCTGTGGACGAAGCTGAAGCTGAGGGTCACTTAGAAGAGCACGAAGACAAGGAAATTCATACTGTTACTGAAATTCTGGACCGAGTGTATATCTGCGAATATTGCGAAATGCCCTACAGCTCtcctaattatttaaaagagcATAGAAcacttcataaaaataaaaaattccactGTACTGTTTGCTCCACTATTTTTTCTGAGTATAAACTATTTAAGTTGCATAAATCATTGCATCCGGTGTACGTAAAcagaagaaaaacatttccTGTGTCCCACTATTTTGTCTGTGATAATTCGggATGCTCCAAGAGCTTTCTGCAATGGGCTACTctaaaacaacataaaaaagTACACGATAATCACCTTAAGTGTCCAAAATGTAAAGCAGTATTCGATAAATCctCGGATTATGAAGATCATATGCAAAAAGTACATCAAGGGCATGACTTCAATTGCCAGTTTTGTGAGAAAGCATTTGGAACAAGACTGGCTCTTGGTGTTCATATTTCAAGAAAGCATACGCAAGaaaaattctTCTGTAACCAATGCGCGTTCAGCTACTCCTCGGAAGCTTTGTTGAAAAATCATCAAGACACAGTTCACACGGACATACCCTGTGAGCAATGCGGCATTGTTTTGAAAAACGCACGAAATTATACTTTGCATCAGAGAGTTGTTCATGAAAGGGAGAAACGATTTTTCTGCAAATACTGCAAGaaaggatttttcaaaaattgtgatGTTATTGCACACGAGCAATCGGTACATCTCAAagtaaaaagatttaaatgtgACTTATGTCCTTATGAAGCGGTGTACAAGGGGTCTTTTACTGTGCATATGAGAGCTCATCGCAATGAAACGCCTTATGAGTGCCACCTTTGCGGTCGAGGCTTCCGGAAAAATGCGTCATTGATAAGCCACATTAAACGACACCAAAATATAAGAGACTTCAAATGCCCTATCGAAGGATGTGAATATGCTTACGTCGAAAAAGGCAATCTTAATTTACACCTTCGTCTAAAGCATCCCAACGGGGAACCAGCTCCAGCCAACCATACTCGACGATCCGGGATAACTCGATCGTACTTTAATGTCCCCAAAACGGATGTTTTTGTTGACGATGATGATGGTTTAAATTTTGGCTCCGATGAGGAGCCACCAGCTAAAACCATCAAAAGAAAACATTCTGAAGAAAGTGATCCTGACGATCCTGTCGTCAACGTTCTGAAGGAGCAGGACTCGGAGCCTGCTGTGATTGTGAGGCGTAATACGAACGATCATGATTACATCGTGCATGGGAATAGTTACGGAAGTGTGATGGAAGACGTTCAAGTAGCAGAAGTGGAGGTTACTTCTAATGATTAG
Protein Sequence
MDLPKCVRCFCDLFDDFQLIFDDTGLELELQKLLSICFDMDIKIRLGEIQALCEDCLNELIDTYDIIQKNEQEGAGPSGNQILSTKIKNENDSPEQNSGSDDFGSFSDEEEIIQKSSRNRDIKERKDIKAKESMLKDKHNLRHKTVKQDTRISKIVEFVEDENSLEEIKKSDENYDVNELDDETSNLEVTEKDNDDCEEYNQVDYLDDFDEEIDFNEYKGRIIQSKFSDVCFPEEIKCRLCETGMKTHLDLMSHTVEMHCVEEFAYPCIVDRECESVSSQEHLTLHLVFKHYDLDSLAIYSKCPECEKRFSDFSSFNKHSCYQLPGKLSRTKVDCDECGKVFTTNKRYRFHLQFHLEKRRPKACFVCETLFRDEDEFFEHVMYNHEKSLDFVCIRCDRYYTSAETFKNHQESHKNERKYACKLCPKTYIYKHFLSDHMITDHDAKSDFKCHICGKYWINKTYLKNHLLTHNKPKPTEVICCNECGFVAVDEAEAEGHLEEHEDKEIHTVTEILDRVYICEYCEMPYSSPNYLKEHRTLHKNKKFHCTVCSTIFSEYKLFKLHKSLHPVYVNRRKTFPVSHYFVCDNSGCSKSFLQWATLKQHKKVHDNHLKCPKCKAVFDKSSDYEDHMQKVHQGHDFNCQFCEKAFGTRLALGVHISRKHTQEKFFCNQCAFSYSSEALLKNHQDTVHTDIPCEQCGIVLKNARNYTLHQRVVHEREKRFFCKYCKKGFFKNCDVIAHEQSVHLKVKRFKCDLCPYEAVYKGSFTVHMRAHRNETPYECHLCGRGFRKNASLISHIKRHQNIRDFKCPIEGCEYAYVEKGNLNLHLRLKHPNGEPAPANHTRRSGITRSYFNVPKTDVFVDDDDGLNFGSDEEPPAKTIKRKHSEESDPDDPVVNVLKEQDSEPAVIVRRNTNDHDYIVHGNSYGSVMEDVQVAEVEVTSND

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00628584;
90% Identity
iTF_00717989;
80% Identity
-