Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.099 1.2e+03 0.7 0.0 26 45 51 70 45 77 0.85

2 5 5.3e-06 0.064 14.4 0.2 23 46 76 99 71 102 0.90

3 5 4.4e-05 0.53 11.4 0.1 20 48 101 128 98 133 0.87

4 5 0.0014 18 6.6 0.1 21 52 130 161 127 162 0.89

5 5 5.2e-05 0.63 11.2 0.3 20 48 157 184 155 187 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.099	1.2e+03	0.7	0.0	26	45	51	70	45	77	0.85
2	5	5.3e-06	0.064	14.4	0.2	23	46	76	99	71	102	0.90
3	5	4.4e-05	0.53	11.4	0.1	20	48	101	128	98	133	0.87
4	5	0.0014	18	6.6	0.1	21	52	130	161	127	162	0.89
5	5	5.2e-05	0.63	11.2	0.3	20	48	157	184	155	187	0.89

Coding Sequence: ATGATATCACCAACGATGGAGGAACCAAAGGTGGTTGATTTAAAGCTAGTTTACACCTGCAGACGCTGCAAAATTTCTTTCAACACAAAACGTGAATCTTTGCTGCACCGAAAaacagtccacgaaggcaatgcggctgataacaagtacatctgcgaaatatgcaacaaaggctttgcaaatccagggaacatgtaccgccatttgaagggccacagcgacgtgcggccccacacctgtaaaatttgcgggagggcgtttgcgcaggcggctaacctccagcgacacctttcagtgcacaacggcgaaaggccctattcgtgccttctttgcgacaagagcttcacccagcagggcaaccttcgaaggcacgagctcacccacaccggggagaagcccttccgctgcaagaggtgcggccggatgttttcgcaaagggtcaatcttaagaagcacgtcatgctccaccaagggtacaagcctttcaactgcgaagtttgccacaaatctttcattcaggcgcagaactacaggaaacatatggaacgcCATGCAAATAATGAAAGTACCGCAACCACAACAAACTATAAGACCGAAAAGACAGAACTATACTATGAGTGCGCTTTGTGCAGAGTTATATTTGCAAATTTGGAAGAGTTCCAGTCGCACGAGGTATTCTGTGAAGTGGCTGGAGAGGAGCAGATAGAAACTACTACTTCAACAGCCGTAACTGACATAGTTGAGAGTACGTAG
Protein Sequence: MISPTMEEPKVVDLKLVYTCRRCKISFNTKRESLLHRKTVHEGNAADNKYICEICNKGFANPGNMYRHLKGHSDVRPHTCKICGRAFAQAANLQRHLSVHNGERPYSCLLCDKSFTQQGNLRRHELTHTGEKPFRCKRCGRMFSQRVNLKKHVMLHQGYKPFNCEVCHKSFIQAQNYRKHMERHANNESTATTTNYKTEKTELYYECALCRVIFANLEEFQSHEVFCEVAGEEQIETTTSTAVTDIVEST

Sequence clustering based on sequence similarity using MMseqs2