Basic Information

Insect: Lucilia sericata
Gene Symbol: zfh1_2
Assembly: GCA_015586225.1
Location: NW:177149-185479[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00013 0.0062 16.6 0.7 1 23 200 222 200 222 0.95

2 15 0.044 2 8.7 1.2 3 23 230 250 228 250 0.95

3 15 0.00014 0.0066 16.5 0.3 1 23 429 451 429 451 0.98

4 15 0.0016 0.074 13.2 0.4 1 23 457 479 457 479 0.98

5 15 1.5e-05 0.00072 19.6 2.8 1 23 511 533 511 533 0.98

6 15 0.011 0.53 10.6 0.3 1 23 557 579 557 579 0.94

7 15 0.0097 0.45 10.8 0.8 1 23 585 608 585 608 0.97

8 15 0.35 17 5.8 0.4 5 19 619 633 616 634 0.91

9 15 0.00021 0.0099 16.0 5.6 1 23 643 665 643 665 0.97

10 15 0.048 2.2 8.6 1.7 2 23 671 692 670 692 0.97

11 15 2.3e-05 0.0011 19.0 0.3 1 23 701 723 701 723 0.98

12 15 0.0063 0.29 11.4 0.2 3 23 731 751 729 751 0.97

13 15 7.6e-05 0.0035 17.4 0.5 1 23 757 779 757 780 0.95

14 15 0.0022 0.1 12.8 0.0 1 23 790 812 790 812 0.97

15 15 0.018 0.85 9.9 0.0 1 20 1411 1430 1411 1433 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00013	0.0062	16.6	0.7	1	23	200	222	200	222	0.95
2	15	0.044	2	8.7	1.2	3	23	230	250	228	250	0.95
3	15	0.00014	0.0066	16.5	0.3	1	23	429	451	429	451	0.98
4	15	0.0016	0.074	13.2	0.4	1	23	457	479	457	479	0.98
5	15	1.5e-05	0.00072	19.6	2.8	1	23	511	533	511	533	0.98
6	15	0.011	0.53	10.6	0.3	1	23	557	579	557	579	0.94
7	15	0.0097	0.45	10.8	0.8	1	23	585	608	585	608	0.97
8	15	0.35	17	5.8	0.4	5	19	619	633	616	634	0.91
9	15	0.00021	0.0099	16.0	5.6	1	23	643	665	643	665	0.97
10	15	0.048	2.2	8.6	1.7	2	23	671	692	670	692	0.97
11	15	2.3e-05	0.0011	19.0	0.3	1	23	701	723	701	723	0.98
12	15	0.0063	0.29	11.4	0.2	3	23	731	751	729	751	0.97
13	15	7.6e-05	0.0035	17.4	0.5	1	23	757	779	757	780	0.95
14	15	0.0022	0.1	12.8	0.0	1	23	790	812	790	812	0.97
15	15	0.018	0.85	9.9	0.0	1	20	1411	1430	1411	1433	0.93

Sequence Information

Coding Sequence: ATGGATAATCATGGCTATGGTGGCATACAGTGGATACAACACCACTCTAGTAATCACTCTTCCTCCCATACGGGAGATATGAAAACTGCTGGTCAGTTGCTAATCGATCCTCAGCCACCGCGTGAAGAGGATCTTATGGCCAGTGCCACCAATTCTTCTGGAGACTTTATGCACACCGAAGATGAAACGGACTCAGCAACTATTGCCCAAATTGCGGCTGAAAATCTTATATTTATGGCACGCGATGGTCAAATGATGACGGAAATTATAACAAATGCTACGACGGATGCCAACGGAACAGTGGTTGTGACTGCCAGTGATGGCGAACAAATTGACTGCGATAGCATTATGGAACAAGCTGCCTTAATTCAACAGCACGAAGATGCTGGTGGTGGAGTGTATAGTGTAGAACATTTTAGCGAGAATACACCGCAAATGGTAACAGAAGAGGTCATCACCGATGATTGGGTGCAGCATCAGGGAGAAGAAAGagttgAAATACCAGCTGAACAAATAATTGGTTCAAGTTCTCAAGTGCTGCTCGATATTGAAGTGCCCCTGCCAACTGTACAAGATGAATATACTGCCCTGCGTCCGTATCCCTGTGACTTTTGTAGTCGACGTTTTCGTAAAAAAGCAAGTCTAATGAATCATATGGTGGCTCATCAAACAGACCGGCCACATTTGTGTAAATTATGTGGAGCCAGATTTCTAAGAAGACAAGATCTCATAAATCATCTAAAAGGACACGCAGAAGAGCCCACAGAACCGCAAATTGATGATAGTGATTTCATACATTTTGTTACCGATACCACTTCTTCCTCACAACGCACTTCCAATGATCATTATTATGAACAAGATTGGAGTGTACCAGAAGATTCAGTAACTATACCAACAAAATCTAGTCgtaaacatcaacaacaacaattacaacatATTACCTCCATTTCTAATCAACCAGTAATGATGGAAAATACTATAACAACAACCTCTTCTTGCATTACACAAGATGCAGTAACAACTCAGCAAACTACAACCGCGCCGCCCAGAGGACGTATAAGTCGTCTGAAGCCTAAAGAGGATACTTCCTATGTGGTTGAAGTAGCCAATAATTGTTCATCAAGTGAAATGATTATAACTTCGGCGTATAGCATTGTAGAGTGCGATACTTTGTCTGCCAATACGGCAGCTGTTAAACTGTCTCAGGATAATACACCCGCTCTGAATGAAAATGAAGAAGAACATAATGTTCTACACTATCCCGTAATAGACGATAGTAAACCATTTGTTTGTCAACAATGTGGTTTGGCATTTTCCCGGGAAAAAGCCATGTTAGCGCATACTAAGACCCATCGCAATGACTCCCCCTTTGAGTGCCCTCAATGTAACGAATTGTTTTGGGATCAAAATAGTTTACAGGATCATCAGAAAACCCATCAATTTGAAGAAAGTAACTCGGAATATGATCCCAATGAAGGCGAAGATGAAACACAAACAGAATCAGAGTCCGAACAACAATTATATGGTGAATTTTATTGTAGTGAATGTGGCATGTCATTTCATCGTCAGGATCTATTAAAACGACATGCTAAAAGTCATCCCTCAGGTAATACCGCAAACATTAGTCAATCTACAAATAATGGTTTGGAAAGTAGCAGTAGAGATCAACATTGTTGTAATACATGTGGAGAAACGTTTGCCGAGGCTTTAGATTTATTAGCACATGCTGAAATACATGCACGTTACCCGCCTTTTAAATGTGTCTTATGCGGTGAATCCTTTTTCGAAGAAACCACCATCAAAAAACATCTACAGTCACAGCATCCTAATGAAATCACTGAAAACTCTTGTATCTTATGTGGCAAAGAGTGTCGTGATCGCAAGGCTTTAATGAAACATGCCTGGGATCATTCACGTGAAAAATGTCACTCTTGCTCGAAATGTGGCAAAAATTTCCACAATAAAGCCCGCCTTAAACGTCACATGGCCTCACATCGTGATAAATCCGTTCAATGTGATGTTTGCCATGAAGAGTTTCCCGATGGTCGTACTCTATCCAATCATCGTCATTCACACAGTGCTACTTCGGCGGGAAAACTATTTCCCTGCCAAGAATGTGGTAAAACCTTTGGCTCTCGCAGTTCTCAGCAGATACATGTACGCATTCACACCGGCGAAAGACCTTATGGTTGTCGTTTTTGTTGGAAAGCTTTTGCTGATGGTGGTACACTGCGTAAACATGAACGTATTCATACGGGAGAGAAACCGTATGCCTGTTCCGTTTGTCCGCGTGCTTTCAATCAACGTGTTGTCTTGCGTGAGCATATACGTTCACATCATTCGGGTTTGGATGCTAAACGAGGAACTTATTACTGTACAGTTTGTGGTGCTGAGTTATCCTCATCGGGTGATCTAATACAACATTTAATACAACACAGTGATATGAATACTGCCATGCAAAGGCAACCCGtgACTGGTCCCCGCAAATATAAACGTCGACGCAAATTGAAGCCCCATGAACTGGCACGACTAAAGCGTGAGGTCAAACATAATGGTGGTACTGGCAGTGATATTGATTTATCCGATTTTGATATAGACAATGTAGACGATCTACTGGCAATGACAACAGACAGCAATACTGCCACTGAAACGGTAACAACCATAAATCAGGAACCAACAAACATCTCCCTACCGGGAAAAGCAACAAAGCGAAAAAATGCCTCCTCTACCTCTACCCCACACTCCGAAAGCAATAATAATAGTAAAACAAAAGCAGCCAGCAACAATAAGACCAACAAAACACACATTTTAGAAGATCAAGAAGACTTTGATTTAGATGTAGGTTTAGATGAGGGTAATGATGAAATTAAGAAACAACGTTATAATTCTTCAAGTAGTGATAAAATCTGGCCAACAAAACAGACTGATGACACATACAAAACCTTGCTGTCAAATTTAGAAACAACAACTTTGTTATCCAGCATAGACACCTTGGTGGTGGGACCCTCAACAAAATCCTCTTCCCATAGCCTAGAAAATAACACAATTGATCCTCAAGCTCGCCAAACAAAGCGTAAAATTAAGCAAGAGTCCAGCTCAACGGCTCAGAGAACTCAACAGGTGCAATTAACAAGAGCAGACAAAGATTCCTCTACTGCCACACATAGCAGAGGTCGTAAAAGTAAAACTGCCACCAACAAACAAAGCAAAGGACCACAAATGATACATACTGAAAAATCTACTATAACAACAACGTCAGACAATGCTGGGGGATCgggcaaaaagaaaacaaaatcaattaTTACCAGAACTCAAACTACAACTTTAGATTTACTGCCAAAAACTTCGGCCATAGTAGATGATTATGACATTATATCGCCTGCCTTGCAGCCACCAAAACAAATCAGCTCTAGTCCTTTGCATATAAAACAGGAACAAGATAATCACAATCACAATTATCACCATAACCAATCCCACCAACAACAGCCGCAGCatcatttaatgaaaaatccTCCAAATACAAATCACAGTACATCTGCCCGAACCCAGTCCAATACCCGCCATACAAACGCCAATGATCTCTATGATGCCCACTTATTGCTGGAGGCTTCATGTCTACGCAGCGATCTAGATGAAATTCTAAGATCACCCTCTAAGTCATCGGATAAATCACGTCAACGTTTTACCAGTGAATCATCTACACAATTTTTAGCCGAACAATCCGAAGAAGAGCAACATTTGATAAAAATTGAACCCACTTCGCCAGATCTGAGGGAAATCGTTAATGGAGCTAGTTCAGTTAGTACCAGTGCAGCACAAGCAGACCTGGAACTGGAAGTTACCAACAGTAAAAGTCgtaaaattaataaatcttCTAGAATTTCGAAAACAAATCGTAAATTTTTAGCTTATCTGGCTGCTGATCTGAATAGTGATGAAACCTCTTCTAATCTTAACAAAAGAACTTCTTCAAATTCACTGCATACAATTCACTCCACAAAATCTGCACGCACTGAACCagctaaaactttaaaaactgtTCAAAATCCCAGTACTACTACATCGTACTTGGACTACACCATGGTGGATACATTTAATACGGTTACAAGTTCCTCTGCGAATAATAACAATTCATTCTCTTCCATCTCGGCTGTAGTTTCGGCAGCCGATGCTTCTGCAGCGGCTCAGCAAAATTCCTCGGCGGCTGCTGTGCGTAAACCTCAGCGCTATTTTGAGTGTGAAATGTGTAGCGCCATATTTTCGGATCGTGCTCAACTATTGGACCATGTGCCCATACATATATAA
Protein Sequence: MDNHGYGGIQWIQHHSSNHSSSHTGDMKTAGQLLIDPQPPREEDLMASATNSSGDFMHTEDETDSATIAQIAAENLIFMARDGQMMTEIITNATTDANGTVVVTASDGEQIDCDSIMEQAALIQQHEDAGGGVYSVEHFSENTPQMVTEEVITDDWVQHQGEERVEIPAEQIIGSSSQVLLDIEVPLPTVQDEYTALRPYPCDFCSRRFRKKASLMNHMVAHQTDRPHLCKLCGARFLRRQDLINHLKGHAEEPTEPQIDDSDFIHFVTDTTSSSQRTSNDHYYEQDWSVPEDSVTIPTKSSRKHQQQQLQHITSISNQPVMMENTITTTSSCITQDAVTTQQTTTAPPRGRISRLKPKEDTSYVVEVANNCSSSEMIITSAYSIVECDTLSANTAAVKLSQDNTPALNENEEEHNVLHYPVIDDSKPFVCQQCGLAFSREKAMLAHTKTHRNDSPFECPQCNELFWDQNSLQDHQKTHQFEESNSEYDPNEGEDETQTESESEQQLYGEFYCSECGMSFHRQDLLKRHAKSHPSGNTANISQSTNNGLESSSRDQHCCNTCGETFAEALDLLAHAEIHARYPPFKCVLCGESFFEETTIKKHLQSQHPNEITENSCILCGKECRDRKALMKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVQCDVCHEEFPDGRTLSNHRHSHSATSAGKLFPCQECGKTFGSRSSQQIHVRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAKRGTYYCTVCGAELSSSGDLIQHLIQHSDMNTAMQRQPVTGPRKYKRRRKLKPHELARLKREVKHNGGTGSDIDLSDFDIDNVDDLLAMTTDSNTATETVTTINQEPTNISLPGKATKRKNASSTSTPHSESNNNSKTKAASNNKTNKTHILEDQEDFDLDVGLDEGNDEIKKQRYNSSSSDKIWPTKQTDDTYKTLLSNLETTTLLSSIDTLVVGPSTKSSSHSLENNTIDPQARQTKRKIKQESSSTAQRTQQVQLTRADKDSSTATHSRGRKSKTATNKQSKGPQMIHTEKSTITTTSDNAGGSGKKKTKSIITRTQTTTLDLLPKTSAIVDDYDIISPALQPPKQISSSPLHIKQEQDNHNHNYHHNQSHQQQPQHHLMKNPPNTNHSTSARTQSNTRHTNANDLYDAHLLLEASCLRSDLDEILRSPSKSSDKSRQRFTSESSTQFLAEQSEEEQHLIKIEPTSPDLREIVNGASSVSTSAAQADLELEVTNSKSRKINKSSRISKTNRKFLAYLAADLNSDETSSNLNKRTSSNSLHTIHSTKSARTEPAKTLKTVQNPSTTTSYLDYTMVDTFNTVTSSSANNNNSFSSISAVVSAADASAAAQQNSSAAAVRKPQRYFECEMCSAIFSDRAQLLDHVPIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00921557; iTF_00331674;
90% Identity: iTF_00921557;
80% Identity: -