Basic Information

Insect: Lucilia cuprina
Gene Symbol: zfh1
Assembly: GCA_001187945.1
Location: JRES01000634.1:135138-143593[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 9.2e-05 0.0061 16.6 0.7 1 23 200 222 200 222 0.95

2 15 0.03 2 8.7 1.2 3 23 230 250 228 250 0.95

3 15 9.8e-05 0.0065 16.5 0.3 1 23 433 455 433 455 0.98

4 15 0.0011 0.073 13.2 0.4 1 23 461 483 461 483 0.98

5 15 1.1e-05 0.00071 19.6 2.8 1 23 515 537 515 537 0.98

6 15 0.0078 0.52 10.6 0.3 1 23 561 583 561 583 0.94

7 15 0.0067 0.45 10.8 0.8 1 23 589 612 589 612 0.97

8 15 0.25 16 5.8 0.4 5 19 623 637 620 638 0.91

9 15 0.00015 0.0098 16.0 5.6 1 23 647 669 647 669 0.97

10 15 0.033 2.2 8.6 1.7 2 23 675 696 674 696 0.97

11 15 1.6e-05 0.001 19.0 0.3 1 23 705 727 705 727 0.98

12 15 0.0044 0.29 11.4 0.2 3 23 735 755 733 755 0.97

13 15 5.2e-05 0.0035 17.4 0.5 1 23 761 783 761 784 0.95

14 15 0.0015 0.1 12.8 0.0 1 23 794 816 794 816 0.97

15 15 0.013 0.84 9.9 0.0 1 20 1411 1430 1411 1433 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	9.2e-05	0.0061	16.6	0.7	1	23	200	222	200	222	0.95
2	15	0.03	2	8.7	1.2	3	23	230	250	228	250	0.95
3	15	9.8e-05	0.0065	16.5	0.3	1	23	433	455	433	455	0.98
4	15	0.0011	0.073	13.2	0.4	1	23	461	483	461	483	0.98
5	15	1.1e-05	0.00071	19.6	2.8	1	23	515	537	515	537	0.98
6	15	0.0078	0.52	10.6	0.3	1	23	561	583	561	583	0.94
7	15	0.0067	0.45	10.8	0.8	1	23	589	612	589	612	0.97
8	15	0.25	16	5.8	0.4	5	19	623	637	620	638	0.91
9	15	0.00015	0.0098	16.0	5.6	1	23	647	669	647	669	0.97
10	15	0.033	2.2	8.6	1.7	2	23	675	696	674	696	0.97
11	15	1.6e-05	0.001	19.0	0.3	1	23	705	727	705	727	0.98
12	15	0.0044	0.29	11.4	0.2	3	23	735	755	733	755	0.97
13	15	5.2e-05	0.0035	17.4	0.5	1	23	761	783	761	784	0.95
14	15	0.0015	0.1	12.8	0.0	1	23	794	816	794	816	0.97
15	15	0.013	0.84	9.9	0.0	1	20	1411	1430	1411	1433	0.93

Sequence Information

Coding Sequence: ATGGATAATGATGGCTATGGTGGCATACAGTGGATACAACACCACTCTAGTAATCACTCTTCCTCCCATACAGGAGATATGAAAACTGCTGGTCAGTTACTAATCGATCCTCAGCCACCGCGTGAAGAGGATCTAATGGCCAGTGCCACCAATTCTTCAGCGGACTTTATGCACACCGAAGATGAAACGGATTCAGCAACTATTGCCCAAATTGCGGCtgaaaatcttatatttatGGCACGTGATGGTCAAATGATGACGGAAATTATAACAAATGCTACGACTGATGCCAACGGAACAGTGGTTGTGACTGCCAGCGATGGCGAACAAATTGACTGCGATAGCATTATGGAACAGGCTGCCTTAATACAGCAACACGAAGATGCTGGTGGTGGAGTTTATACTGTGGAACATTTTAGCGAGAACACACCGCAAATGGTAACGGAAGAGGTCATCACTGATGATTGGGTGCAGCATCAGGGAGAAGAAAGAGTTGAAATACCCGCAGAACAAATAATTGGTTCTAGTTCCCAAGTGCTGCTCGATATTGAAGTGCCCCTGCCAACTGTACAAGATGAATACACTGCTCTGAGACCGTACCCCTGTGACTTTTGCAGTAGACGTTTTCGTAAAAAAGCAAGCCTAATGAATCATATGGTGGCGCATCAAACAGATCGGCCACATTTGTGTAAATTATGTGGAGCCAGATTTCTAAGAAGACAAGATCTCATAAATCATCTAAAAGGGCATGCAGAAGAGCCCGCAGAACCGCAAATGGATGATAGTGATTTTATACATTTTGTTACCGATACCACCTCTTCCTCACAACGCAACTCCAATGATCATTATTATGAACAAGATTGGAGTGTACCAGAAGATTCAGTAACAATACCAACAAAATCTAGTCgtaaacatcaacaacaacaacagcaacaattgcaACATATTACCTCTATTTCTAATCAACCAATAATGATGAATGAAAATACTATAACAACTACTTCCTCCTGCAATACACAAGATATACTAACAATTCAGCAAACTACAACAGCACCGCCCAGAGGACGTATAAGTCGCCTAAAGCCTAAAGAGGATACTTCCTACGTGGTGGAAGTAGCCAATAATTGTTCATCAAgtgaaatgattattacttcgGCGTATAGCATTGTAGAATGTGATACGTTGTCGGCCAATACGGCAGCTGTTAAACTATCTCAGGATAATACACCCGCTCTGCATGAAAATGAAGAAGAACATAATGTTCTACACTATCCCGTAATAGACGATAGTAAACCATTTGTTTGTCAACAATGTGGTTTGGCATTTTCCCGTGAAAAGGCCATGTTAGCGCATACTAAgACACATCGCAATGACTCTCCCTTTGAGTGCCCTCAATGTAATGAATTATTTTGGGATCAGAATAGTTTACAGGATCATCAGAAAACCCATCAATTTGAAGAAAGTAATTCGGAATACGATCCCAATGAAGGCGAAGACGAAACACAAACAGAATCAGAGTCCGAACAACAATTATATGGTGAATTTTACTGTAGTGAATGTGGCATGTCATTCCATCGTCAGGATCTATTAAAACGACATGCTAAAAGTCATCCCACAGGTAATGCCGCAAATATTAGTCAATCTACAAATAATGGTTTGGAAAGTAGCAGTAGAGATCAACATTGTTGTAATACATGTGGAGAAACATTCGCCGAAGCTTTAGATTTATTAGCGCATGCCGAAATACATGCACGTTACCCACCCTTTAAaTGTGTCTTATGCGGAGAATCCTTTTTCGAGGAAACCACCATCAAAAAACATCTGCAGTCACAGCATCCCAATGAAATCACTGAAAACTCTTGTATATTATGTGGCAAAGAGTGCCGTGATCGCAAGGCTTTAATGAAACATGCCTGGGATCATTCACGTGAAAAATGTCACTCTTGTTCGAAATGTGGCAAAAATTTCCACAATAAAGCCCGCCTTAAACGTCACATGGCTTCACATCGTGATAAATCCGTTCAATGTGATGTCTGCCATGAAGAGTTTCCCGATGGTCGTACTCTCTCCAATCATCGTCATTCACACAGTGCTACTTCAGCGGGAAAACTATTTCCCTGTCAAGAATGTGGTAAAACCTTTGGCTCTCGCAGTTCACAACAGATACATGTGCGCATTCACACCGGCGAAAGACCTTATGGATGTCGTTTTTGTTGGAAAGCTTTTGCAGATGGTGGTACACTACGTAAACATGAACGTATTCATACGGGAGAGAAACCGTATGCTTGTTCTGTTTGCCCACGTGCTTTCAATCAACGTGTTGTCTTGCGTGAGCATATACGTTCACATCATTCGGGATTGGATGCCAAAAGAGGCACTTATTACTGTACAGTTTGTGGTGCTGAGTTATCCTCATCGGGTGATCTTATACAACATTTAATACAGCACAGTGATATGAATACTGCCATGCAAAGGCAACCcgtgACTGGTCCCCGCAAATATAAACGTCGACGCAAATTGAAACCCCATGAACTGGCACGACTTAAACGTGAAGTAAAACATAACGGTGGTGCTGGCAGTGATATTGATTTATCCGATTTTGATATAGACAATGTAGACGATCTGCTGGCAATGACAACAGACAGCAATACTGCCACTGAAACAGTAACAACCATAAATCAGGAACCAGCAAACATCTCCCTACAAGGAAAAACAACCAAACGCAAAAATGCCTCCTCTAACCCACACTCCGAAAgcaataataatagtaaaacaAAGGCAACTAACAACAATAAGACCAACAAATCACACATTGTTGAAGATCAAGAAGATTTTGATTTAGATGTAGGTTTAGATGAGGGTAATGATGAGATTAAGAAACAACGTTATAATTCTTCGAGTAGTGATAAAATCTGGCCAACAAAACAGACTGATGACACATACAAAACCTTGCTGTCAAACTTAGAAACAACTACTTTATTATCTAGCATTGATACATTGGTGGTGGGACCCTCAACAAAATCCTCTTCCCATAGCctagaaaataatacaaatgatACTCAAGCACGTCAAACAAAGCGTAAAATAAAGCAAGAGTCCAGCTCAACAGCGCAGAGAACTCAACAAGTGCAATTAACAAGAGCAGACAAAGATTCCCCTACTGCCACAAATAGCAGAGGTCGTAAAAGTAAAACTGCCACCAATAAACAAACCAAAGGACCACAAATGATACATACCGAAAAATCTACTATAACAACAATGTCAGACAATGCTGGAGGATCaggcaaaaagaaaacaaaatcaattattaCCAGAACACAAACTACAACTTTAGATTTACTGCCAAAAACTTCGACCATAGTAGATGATTACGATATTATATCGCCTGCCTTACAGCCACCAAAACAAATCAGCTCTAGTCCTTTGCATATAAAACAGGAACAAGATAATCATAATCACAACTATCACCATCATCAGTCCCACCAACAACAGTCTCAGcatcatttaatgaaaaatcctCCAAATACAAATCACACTACATCTGCACGAACCCAGTCCAATACCCGCCATACAAACGCCAATGATCTCTATGACGCGCACTTATTGCTGGAGGCTTCATGTCTACGCAGCGATCTAGATGAAATTCTAAGATCACCCTCCAAGACATCGGATAAATCGCGGCAACGTTTTACCAGTGAATCCTCTACACAATTTTTAGCCGAACAATCCGAAGAAGaacatttgattaaaattgaACCCACTTCACCAGATCTGAGGGAAATTGTCAATGGTGCTAGTTCAGTTAGTACCAGTGCAGCACAAGCTGACCTGGAACTGGAAGTTAGCAATAGCAAAAGTCGTAAAATGAATAAATCTTCTAGAATTTCGAGAACAAATCGTAAATTTTTAGCTTATTTGGCCGATGATCTGAATAGCGATGAAACCTCCTCTGATCTTAACAAAAGAACTTCAAATTCACTGCATACAATTCACTCAACAAAATCTGCCCGCACTGAACCAGCTAAATCACTAAAATCTGTTCAAAATCCCAGCACTACTACATCGTATTTGGATTACACCATGGTGGATACTTTTAATACGGTTACAAGTTCCTCGGCGAATAATAACAATTCATTCTCTTCCATTTCGGCAGTAGTTTCAGCAGCCGATGCTTCTGCAGCAGCTCAGCAAAATTCATCGGCGGCTGGTGTGCGTAAACCTCAGCGCTATTTTGAGTGTGAAATGTGTAGTGCTATATTTTCGGATCGTGCTCAACTATTGGATCATGTAcccatacatatataa
Protein Sequence: MDNDGYGGIQWIQHHSSNHSSSHTGDMKTAGQLLIDPQPPREEDLMASATNSSADFMHTEDETDSATIAQIAAENLIFMARDGQMMTEIITNATTDANGTVVVTASDGEQIDCDSIMEQAALIQQHEDAGGGVYTVEHFSENTPQMVTEEVITDDWVQHQGEERVEIPAEQIIGSSSQVLLDIEVPLPTVQDEYTALRPYPCDFCSRRFRKKASLMNHMVAHQTDRPHLCKLCGARFLRRQDLINHLKGHAEEPAEPQMDDSDFIHFVTDTTSSSQRNSNDHYYEQDWSVPEDSVTIPTKSSRKHQQQQQQQLQHITSISNQPIMMNENTITTTSSCNTQDILTIQQTTTAPPRGRISRLKPKEDTSYVVEVANNCSSSEMIITSAYSIVECDTLSANTAAVKLSQDNTPALHENEEEHNVLHYPVIDDSKPFVCQQCGLAFSREKAMLAHTKTHRNDSPFECPQCNELFWDQNSLQDHQKTHQFEESNSEYDPNEGEDETQTESESEQQLYGEFYCSECGMSFHRQDLLKRHAKSHPTGNAANISQSTNNGLESSSRDQHCCNTCGETFAEALDLLAHAEIHARYPPFKCVLCGESFFEETTIKKHLQSQHPNEITENSCILCGKECRDRKALMKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVQCDVCHEEFPDGRTLSNHRHSHSATSAGKLFPCQECGKTFGSRSSQQIHVRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAKRGTYYCTVCGAELSSSGDLIQHLIQHSDMNTAMQRQPVTGPRKYKRRRKLKPHELARLKREVKHNGGAGSDIDLSDFDIDNVDDLLAMTTDSNTATETVTTINQEPANISLQGKTTKRKNASSNPHSESNNNSKTKATNNNKTNKSHIVEDQEDFDLDVGLDEGNDEIKKQRYNSSSSDKIWPTKQTDDTYKTLLSNLETTTLLSSIDTLVVGPSTKSSSHSLENNTNDTQARQTKRKIKQESSSTAQRTQQVQLTRADKDSPTATNSRGRKSKTATNKQTKGPQMIHTEKSTITTMSDNAGGSGKKKTKSIITRTQTTTLDLLPKTSTIVDDYDIISPALQPPKQISSSPLHIKQEQDNHNHNYHHHQSHQQQSQHHLMKNPPNTNHTTSARTQSNTRHTNANDLYDAHLLLEASCLRSDLDEILRSPSKTSDKSRQRFTSESSTQFLAEQSEEEHLIKIEPTSPDLREIVNGASSVSTSAAQADLELEVSNSKSRKMNKSSRISRTNRKFLAYLADDLNSDETSSDLNKRTSNSLHTIHSTKSARTEPAKSLKSVQNPSTTTSYLDYTMVDTFNTVTSSSANNNNSFSSISAVVSAADASAAAQQNSSAAGVRKPQRYFECEMCSAIFSDRAQLLDHVPIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00922285;
90% Identity: iTF_00922285;
80% Identity: -