Lcup004908.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lucilia cuprina
Gene Symbol
spopl
Assembly
GCA_001187945.1
Location
JRES01001701.1:1614181-1627191[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.18 68 3.4 0.0 5 30 138 163 134 167 0.85
2 4 6.2 2.4e+03 -1.6 0.0 66 82 385 403 378 414 0.70
3 4 1.3e-17 5.1e-15 55.3 0.0 21 108 897 985 892 987 0.95
4 4 1.5 5.9e+02 0.3 0.0 79 110 988 1019 984 1019 0.86

Sequence Information

Coding Sequence
ATGGCAGCTGTTGAACATACCTTTCATGGTACTTGGGAGATTGTTTCCTGTACCtttgaaggaaaaaaagaaatatccgGTTTAGAGggcATTAAATTTCGTCTGGACGATACAAGTGATATAACATGGTATAATGATTTGGTCAGCCCGTTGCCAGAAACAAAAGACTGCGATACATGTTGTGATTCGGCTAGTGTTCTTTTCAGTTGTGAAACTTTTGAAGTTAATGAAAGCAATCCACGTTTAATATTTGGAGCGTTTGCTGGGCACAGTATAGAATTTAatACATCTACCTTAACACCTTCTGATTCCCTAATACTTTACTGTGAAAACTGGTATGCGGTGGAATGTAAACGTTTGAAAGAGGGCCAAGCTGCTGGCCAGGAAAAAGAATTCTCTTTTGCCGAAGCCTTAAATGAATCATACTTTAGTGATGTTATTATCAAAAGCTCTGATGGATTTGAGTATCACGTACATGCTTCTATATTACGTCTAAATGGATTTGATTGCAGTATGTGTGTACATGCTACCAGCGCCATTTCATTGCCTCAGACTGTATGTAGAAATTATGATTCTcttaccataaaaagtaaagatAATGCCAGTTTACCCAATTCCCCGAATCCCATAAAAATTTCGGTGACAATGACCAGCACCACAAAACAAACGGAACAGGAGCAGCAAAAATCTTTACCCCGCCTCAATTTATCACCCATTTACTTGCAACCGCCTACAGAATCATGTCATGCCAACAATAACACTTCTCTTAGAACTCAACATCACTCCCAGTTGTCGTCCTCCTTTAATTGTTTGTCGACCAAGACCCAAGCGAATGGTAGTACCTTACATCTACTCAATCAAGAGAGTGGTTCCGGCATGCGTCGTTTTCCACCTAATTCCCATTCGGATTCTCATTTGGAAACCCATTATTTAAAACCTCaatcaaagaatatttttaatttttgtcaagATCTCATGTTGCAACATTCAACGGATGTATGCAGTTCAACCGGTTGTAATACACGTCGACCACCTTTATCACCCTATCGTGCCAGAAGTCCTTCACCATTTCCCAGTTCTATGGATACACCACCTTCGTCACCCTTGACTCCGGTGGGTGTTTTATATGATCTTCCTGCTTTTCTACTAACGCCCATATTACATTGGCTTTATACGGAATCATTGATGCCCGATATGAACGAGGATGTTTGCGAGAAACTTATCAATTTTGCCGAGTCCCAACCTTCGTTAATGAAGTTGGCTGAACCCgcaaaaagatatttaaaaatgataaaattgaaGAAGTTTGTTGTCAATATAATAATGGATTTACATAGTATTTTAAATCGTGTCATACAAACCATTAATCCAGTTACTATATCACATGAACCCGCCTTACTTTATGCCACATTTAAGGATAGTTTAAGAGAATGTTCTATAGGATGTgccaaaattttacaattttgcaatatatttattaagGATGCCGCCGATATAGCACGTtatcaaaaaaatgaaataattaaatatgtacgCACACGTATACCCATATTTATGTCACAATTGCATCAGCTCTTACGCaatatattaaatgtatttttaagtcTAACACCTGATGAAAAAGATGAATTAGCTAATTACTTAGTACCTGAGATTGAAACCACTTTATTGATTTTAACTAGTGTGATAGaagaaatcaaaaattctttagaaaaaatgtgtaaagATTTAAAATGCTCACATTTAGATTTATCCTTAAAATATGCTACCGATGATGCGGTAGCTAtgcaaatacaaaataacactTTCATTACCGCCAACAATGCCATGGATGATAATACCGTTAGCACATTATTTAGTCAGCCGCCATTATCGCCACGTCCTCGCCGAGGTCCACCCATAGGTTTGACGCTCTATGATAATCCCTCGGATAAGCAACGTCTAATGAGTGccgaaaatgatttaaaatttgttttatacatgTATGAGGTGAGAAAAATGAGAGATATTTATGGACGTATATCAGCTGCTTTGGATATAATAAGAGATAAAAAAACTACTTATTGTGAAATGGATTTCTTGAGTAAACGCAGCactataaatcaaaatttagaaCAATTGATTGTTGATATACCCAGTTATATATTGATTATGGAAAATCTATCGGATCGTTTGGAGGAGAAATTGGGTTGGaaggaatttaaattttgttttaagttggCAACTTCGCAAATTAACGGTGTTATAGTGAAGATATTTGATCATAAGTCTGCATTAAAAGAAGCCATGAGTCAGATTTGCAAGCTGGTGCAAAAACAAGAATTTACACAAACTCTAATCGAATTAGGATTATTGGAACCGTCAAACATTTTAGAAAGTGAATTGAAATCATTGCAAAAAGATGATCCCTTTGAATTAAGTTTAGATCCTTTGCTTTTGGAAAGGCAACATAACTATGATTATAAAAGTGTTAAgCTTAATCTAATACGTCACTTATGTGAACCACCCATAGCGGTGAATAGTAATCTGTCGAAAAATGCTTTACGTCTCTTGCACTCAGCCCAATTGGCCGATATGGAATTTGAAGTTCATACTTTCTATAATCCTCAAACAGTTGAGTCTAGTATTGCAAATAGAAATACTTTAGATATACAAAGTATGGAGGCTCTTAAAGCACCCATACAAGTTCATACATTTCGTGCACATCGTGTAATTGTATCGGCCAGATGTGAATGGTTTAAAAAGGCTTTAATGTCTGGTATGCAGGAATGTTTAACAAGaaaaattattataactgATACTTCACCGGTGATCTTTCGCCGTTTACTGTTATTTTTGTATGGTGCTCCGATTGATAAAACTGTTGGTGCTGAACAAATATGTGAATTGATGTTATTAGCtgataaatattctatagatgATTTAAAGGAATTAtgtgaaaatactttaaattcaCAAATCGATGAACACTCTGTTTTATGTCTATTGGGTATAGCCGATCATTATATGGCATCGGCTTTAAAATCTAAGTGTCTTTCATATCTATCACAAAATTCACATCTTACAAAGGCTGCTATGTTTAAGGAATTATCACGACCCTTGCAaCTTGAGGTAATGGATTTGATACATTGGTATGGTCGTGTTACTGAACCCTGGACTGATACGGGCGGTTTTAAACCACGCAGCACTTCCAGACACAGTTTAAAAAGTCCCTCTAAACCCCGCTCACGTTCTAGAAAATCATCACCATCTTTTATGTGA
Protein Sequence
MAAVEHTFHGTWEIVSCTFEGKKEISGLEGIKFRLDDTSDITWYNDLVSPLPETKDCDTCCDSASVLFSCETFEVNESNPRLIFGAFAGHSIEFNTSTLTPSDSLILYCENWYAVECKRLKEGQAAGQEKEFSFAEALNESYFSDVIIKSSDGFEYHVHASILRLNGFDCSMCVHATSAISLPQTVCRNYDSLTIKSKDNASLPNSPNPIKISVTMTSTTKQTEQEQQKSLPRLNLSPIYLQPPTESCHANNNTSLRTQHHSQLSSSFNCLSTKTQANGSTLHLLNQESGSGMRRFPPNSHSDSHLETHYLKPQSKNIFNFCQDLMLQHSTDVCSSTGCNTRRPPLSPYRARSPSPFPSSMDTPPSSPLTPVGVLYDLPAFLLTPILHWLYTESLMPDMNEDVCEKLINFAESQPSLMKLAEPAKRYLKMIKLKKFVVNIIMDLHSILNRVIQTINPVTISHEPALLYATFKDSLRECSIGCAKILQFCNIFIKDAADIARYQKNEIIKYVRTRIPIFMSQLHQLLRNILNVFLSLTPDEKDELANYLVPEIETTLLILTSVIEEIKNSLEKMCKDLKCSHLDLSLKYATDDAVAMQIQNNTFITANNAMDDNTVSTLFSQPPLSPRPRRGPPIGLTLYDNPSDKQRLMSAENDLKFVLYMYEVRKMRDIYGRISAALDIIRDKKTTYCEMDFLSKRSTINQNLEQLIVDIPSYILIMENLSDRLEEKLGWKEFKFCFKLATSQINGVIVKIFDHKSALKEAMSQICKLVQKQEFTQTLIELGLLEPSNILESELKSLQKDDPFELSLDPLLLERQHNYDYKSVKLNLIRHLCEPPIAVNSNLSKNALRLLHSAQLADMEFEVHTFYNPQTVESSIANRNTLDIQSMEALKAPIQVHTFRAHRVIVSARCEWFKKALMSGMQECLTRKIIITDTSPVIFRRLLLFLYGAPIDKTVGAEQICELMLLADKYSIDDLKELCENTLNSQIDEHSVLCLLGIADHYMASALKSKCLSYLSQNSHLTKAAMFKELSRPLQLEVMDLIHWYGRVTEPWTDTGGFKPRSTSRHSLKSPSKPRSRSRKSSPSFM