Agra010028.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Aldrichina grahami
Gene Symbol
spopl
Assembly
None
Location
Contig114:1112450-1121646[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.31 70 3.2 0.0 5 30 138 163 134 167 0.85
2 4 7.7 1.7e+03 -1.3 0.0 66 82 383 401 376 426 0.74
3 4 1.2e-17 2.7e-15 56.0 0.0 21 108 881 969 876 971 0.95
4 4 3.5 8e+02 -0.2 0.0 79 109 972 1002 968 1003 0.85

Sequence Information

Coding Sequence
ATGGCAGCTGTTGAACATACCTTTCATGGTACTTGGGAGATTGTTTCCTGTACCTTTGAAGGGAAAAAAGAAATATCCGGCTTAGAGGGCATTAAATTTCGTTTGGACGATACCAGTGATATAACATGGTATAATGATTTGGTCAGCCCGTTGCCAGAAACAAAAGACTGCGATACATGTTGTGATTCGGCTAGTGTTCTATTCAGTTGTGAAACTTTTGAAGTCAATGAAAATAATCCACGTTTAATATTTGGTGCATTTGCTGGACACAGTATAGAATTTAATACATCTACCTTAACACCCTCTGACTCATTAATACTCTACTGTGAGAACTGGTATGCGGTGGAATGTAAACGTTTAAAGGAGGGACAGGCTGCTGGACAGGAAAAGGAATTCTCATTTGCCGAAGCCTTAAATGAATGCTACTTTAGTGATGTCATTATTAAAAGTTCCGATGGCTTTGAGTACCACGTGCATGCCTCTGTATTACGTTTAAATGGTTTTGATTGCAGCATGTGTGTGCATGCCACAAGCACCATCTCATTGCCACAAGCTGTATGTAGAAATTATGATTCCCTTACCATAAAAAGTAAAGATAATGCCAGTCTACCCAACTCTCCAAATCCCATTAAAATCTCCGTGACCATGACCAGCACCACAACACAACCGGAAGAACAGCAAAAATCTTTACCCCGCCTCAATTTATCACCCATATACTTGCAACCGCCTACAGAATGTCATGCCACAAATACCACCTCCTTGAGATCCCAGCATCATACACAATTGTCGTCCTCTTTTAATTGCTTGTCGACTAAGGTCCAACCGAATGGTGGTACCTTACATCTGCTGAATCAAGAGAGTGGCTCTGGCATGCGTCGTTTCCCTCCCAATTCCCATTCGGATTCGCATTTGGAAACACATAATTTACAGCCACAATCAAAAAATATCTTTAATTTTTGTCAAGATCTCATGCTGCAACATTCCACGGAAGTTTGCAGTTCAACGGGTTGTAATACACGCCGGCCACCCTTGTCCCCCTATCGTGCCAGAAGTCCCTCACCATTTCCCAGTTCTATGGATACACCGCCCTCATCGCCCTTGACTCCGGTGGGTGTTTTATATGATCTTCCTGCTTTTCTATTGACACCCATATTGCATTGGCTTTATACCGAGTCCCTGATGTCCGATATGAATGAGGATGTTTGTGAGAAACTCATCAACTTTGCCGAGACTCAGCCTTCGCTAATGAAATTGGCAGAACCCGCTAAGAAGTATTTGAAGATGATTAAGTTGAAAAAGTTTGTTGTCAATATTATAATGGATCTACATAGTATTCTAAATCGTGTCATACAAACCATTAATCCAGTTACTATATCACACGAACCCGCCTTACTATATGCCACATTTAAGGATAGTTTAAGAGAATGTTCTATAGGATGTGCCAAAATTTTACAATTTTGCAATATATTTATTAAGGATGCCGCCGATATAGCACGCTATCAAAAGAATGAAATAATTAAATATGTACGCACACGTATACCCATATTTATGTCACAATTGCATCAGCTCTTACGCAATATATTAAATGTATTTTTAAGTCTAACACCTGATGAAAAAGATGAATTAGCTAATTACTTAGTACCTGAGATTGAAACCACTTTATTGATTTTAACTAGTGTGATAGAAGAAATCAAAAATTCTTTAGAAAAAATGTGTAAAGATTTGAAATGCTCACATTTAGATTTATCCTTAAAATATGCTACCGATGATGCGGTAGCCATGCAAATACAAAATAACACTTTCATTACCCCACCGCTATCGCCAAGACCCAGAAGAGGACCACCCATAGGTCTAACCCTGTATGATAATCCTTCAGACAAGCAACGCTTAATGAGTGCCGAAAATGATTTGAAATTTGTCTTGTACATGTACGAAGTGAGAAAAATGCGTGATATTTATGGACGCATATCTGCTGCTTTGGAAATCATAAGGGATAAAAAAATTACTTATTGTGAGATGGATTTCCTGAGTAAGCGCAGCACTATTAATCAAAATTTAGAGCAATTGATTGTGGATATACCGAGTTATATATTGATTATGGAAAATCTATCCGATCGTTTGGAGGCGAAATTGGGCTGGAAGGAATTCAAGTTTTGTTTCAAATTGGCGACATCACAAATTAATGGTGTCATAGTAAAGATATTTGATCATAAGTCTGCTTTAAAAGAGGCCATGAGTCAGATCTGTAAACTGGTGCAAAAACAAGAATTTACACAAACTCTTATCGAGTTGGGCTTATTGGAACCTTCAAATATATTAGAAAGTGAATTGAAATCATTGCAAAAAGATGATCCCTTTGAATTGAGTTTAGATCCTTTGGTTATGGAACGGCAACACAACTATGACTATAAAAGTGTTAAGCTTAATCTTATACGACATCTTTGTGAACCACCCATAGCGGCAAATAGTAATTTATCGAAAAATGCTTTGCGTCTTTTGCACTCGGCCCAATTGGCCGATATGGAATTTGAAGTGCATACATTTCAGCAGGCCCTTTTGACAACAGCAGAAAGCAATGTCTTGAATAAAAATACTTTAGATATACAGAGTATGGAAACCCATAAAGCTCCCATACAGGTGCATACATTTCGGGCACATCGTGTTATAGTATCGGCCAGATGTGAATGGTTTAAGAAGGCCTTAATGTCGGGCATGCAGGAGAGCTTAACAAGAAAAATCATTATAACTGATACATCTCCAGTGATCTTTAGACGATTACTGTTGTTTTTATATGGTGCTCCAATTGATAAAACTGTGGGAGCTGAACAAATATGTGAATTGATGTTATTAGCTGATAAATACTCTATAGATGATTTAAAGGAATTGTGCGAAAATACTTTAAATTCGCAAATAGATGAACATTCTGTTTTATGTCTTTTGGGTATAGCCGATCATTATATGGCATCGGCTTTAAAATCTAAGTGTCTTTCATTTGTATCACAAAATTCACATCTTACTAAGGCTGCTATGTTTAAGGAACTATCACGACCCTTACAACTAGAGGTTATGGATTTGATACATTGGTATGGTCGTGTGGCTGAACCCTGGACAGATTCGGGCGGTTTTAAACCACGCAGCACTTCCAGACACAGCCTGAAAAGTCCCTCGAAACCCCGATCACGTTCCAGAAAATCCTCACCATCTTTTATGTGA
Protein Sequence
MAAVEHTFHGTWEIVSCTFEGKKEISGLEGIKFRLDDTSDITWYNDLVSPLPETKDCDTCCDSASVLFSCETFEVNENNPRLIFGAFAGHSIEFNTSTLTPSDSLILYCENWYAVECKRLKEGQAAGQEKEFSFAEALNECYFSDVIIKSSDGFEYHVHASVLRLNGFDCSMCVHATSTISLPQAVCRNYDSLTIKSKDNASLPNSPNPIKISVTMTSTTTQPEEQQKSLPRLNLSPIYLQPPTECHATNTTSLRSQHHTQLSSSFNCLSTKVQPNGGTLHLLNQESGSGMRRFPPNSHSDSHLETHNLQPQSKNIFNFCQDLMLQHSTEVCSSTGCNTRRPPLSPYRARSPSPFPSSMDTPPSSPLTPVGVLYDLPAFLLTPILHWLYTESLMSDMNEDVCEKLINFAETQPSLMKLAEPAKKYLKMIKLKKFVVNIIMDLHSILNRVIQTINPVTISHEPALLYATFKDSLRECSIGCAKILQFCNIFIKDAADIARYQKNEIIKYVRTRIPIFMSQLHQLLRNILNVFLSLTPDEKDELANYLVPEIETTLLILTSVIEEIKNSLEKMCKDLKCSHLDLSLKYATDDAVAMQIQNNTFITPPLSPRPRRGPPIGLTLYDNPSDKQRLMSAENDLKFVLYMYEVRKMRDIYGRISAALEIIRDKKITYCEMDFLSKRSTINQNLEQLIVDIPSYILIMENLSDRLEAKLGWKEFKFCFKLATSQINGVIVKIFDHKSALKEAMSQICKLVQKQEFTQTLIELGLLEPSNILESELKSLQKDDPFELSLDPLVMERQHNYDYKSVKLNLIRHLCEPPIAANSNLSKNALRLLHSAQLADMEFEVHTFQQALLTTAESNVLNKNTLDIQSMETHKAPIQVHTFRAHRVIVSARCEWFKKALMSGMQESLTRKIIITDTSPVIFRRLLLFLYGAPIDKTVGAEQICELMLLADKYSIDDLKELCENTLNSQIDEHSVLCLLGIADHYMASALKSKCLSFVSQNSHLTKAAMFKELSRPLQLEVMDLIHWYGRVAEPWTDSGGFKPRSTSRHSLKSPSKPRSRSRKSSPSFM