Basic Information

Insect: Lordiphosa andalusiaca
Gene Symbol: ftz-f1
Assembly: GCA_035044965.1
Location: JAWNNM010002218.1:208583-238318[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 3 2.1e+04 -6.8 18.5 37 160 18 138 1 151 0.42

2 3 4.2e-19 3e-15 56.8 0.2 1 76 320 395 320 460 0.76

3 3 1.9e-70 1.4e-66 225.9 2.3 157 408 556 800 538 802 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	3	2.1e+04	-6.8	18.5	37	160	18	138	1	151	0.42
2	3	4.2e-19	3e-15	56.8	0.2	1	76	320	395	320	460	0.76
3	3	1.9e-70	1.4e-66	225.9	2.3	157	408	556	800	538	802	0.92

Sequence Information

Coding Sequence: ATGGATCAACAACAGGCGACAGTGCAATTCATCTCGTCGCTGAATATGTCGCCATTTAGCATGCaactggagcagcagcaacagcagccctCCAGTCCCGCTTTGGCCAcaaatcagcagcagcaacagaatagcaacaataacaacaacaacaacaacaacaacaatgataaTGATGGATTGAATTCCGATAACGACTACAGCGCCTATACGTTGCAACTGACGGGTGGTGCAGGTGGTGGCGGATCCACACACCACACCCatcaccagcaacagcagcagcagcagcaacattaccaacagcaacaacaacaacaacagcagcaacagaataTAGCCAACAATGCCAATCAATTCAATTCCTCATCCTATTCgtatatatacaattttgaCTCACAGTATATATTCCCGACAGGCTATCAAGATACCACCTCCTCGCACTCACAACAgagtggcggtggcggcggaggaggcggtggcggcggcagcggcggagCTGGCaatcttttgaatggcagctcCGGCGGCAGTTCAACCGGTGGCTACATGCTACTCCCGCCTGCCACAAATTCCTCGGGCCAGAACAACAATTCCGGCCACATGTCCAGCGGTGGCGGTCCACAGAATTCCGGTCCCGGTGGTGGTAacggcggcaacaacaactctGGCCATCCACATGGCGGCACCAGCGCCACCTCGGGACACTCGTCGGGCGAGGCTATTGATTTTAAGCATCTCTTCGAGGAACTGTGCCCGGTCTGTGGCGATAAAGTCAGTGGCTATCATTATGGCCTGCTAACCTGTGAATCCTGCAAGGGTTTCTTCAAGCGTACGGTACAAAACAAGAAGGTGTACACCTGTGTGGCCGAACGATCGTGTCACATTGACAAAACGCAGCGGAAAAGATGTCCCTATTGCCGTTTCCAGAAATGCTTGGAAGTGGGCATGAAATTGGAGGCTGTTCGTGCGGATCGAATGCGTGGCGGACGAAATAAGTTTGGACCCATGTACAAGCGGGATCGGGCGCGAAAACTGCAAGTGATGAGACAACGACAATTGGCACTACAAGCGTTGCGCAGTTCCATGGGCACGGATATTAAACCGACGCCCCTCTCGCCTGGCTATCAGCAAGCATATCCAAATATGAACATTAAgcaagaaatacaaataccTCAGGTAAGGAAGACGTTCCAACaaccggtttgcatccctggtaaatatgtttatatatatgcCGATACCAACCTGGATACGGAAATACAAATCCAGgTATCCTCACTCACGCAATCGCCCGACTCATCGCCCAGCCCCATAGCCATTGCCTTGGGTCAGGTGAACGTAAGCACAGGCGGTGTGATAACCACGCCCATGAATGCTGGCAATGTTGGTGGCATCACTGGCGGCAACTCTGCGGGCAACGGCGGCAGTAATAATCAGAATAGTAGCAGTACAGGCAGCGGCACCGGAGCTGGCGGTGGAGGAGGCAATAATgcgggcggcggcggcggcggcggtggcaatAATTCTGGCGACGGCCTGCAACGCAGTGGAGCCggcggtggaggaggaggcggcggtAATGGCAGCAATTGTCATGAACCTGGAATTGGATCTCTGCAGAATACGGCCGAATCGAAATTGTGcttcgATTCTGGTACCCATCCATCGAGCACAGCCGATGCGCTCATAGAGCCCCTGagagtcTCCCCCATGATACGTGAGTTTGTGCAATCGATCGATGATCGGGAATGGCAAACGCAACTGTTTGCCTTGCTGCAGAAACAGACCTACAATCAAGTCGAAGTGGATCTCTTTGAGCTAATGTGCAAAGTGCTCGATCAGAATTTGTTCTCGCAAGTCGATTGGGCAAGAAACACCGTCTTCTTTAAGGATTTGAAGGTGGATGATCAAATGAAGCTACTGCAACACTCCTGGTCCGATATGCTCGTCCTCGATCATCTGCACCATCGCATCCATAATGGCCTGCCCGATGAGACGCAACTGAATAATGGTCAGGTCTTCAATCTCATGAGTCTTGGCCTGCTGGGCGTTCCCCAACTGGGTGACTATTTCAATGAGCTGCAAAATAAGTTGCAGGATCTGAAATTCGATATGGGCGATTATGTATGCATGAAATTCCTAATCCTGTTGAATCCCAATGTACGAGGAATTGTCAACAAGAAAACCGTCTCCGAGGGACACGATAATGTCCAGGCAGCATTACTGGACTACACGCTAACGTGTTATCCCTCAGTTAATGACAAATTCAGTAGGCTAGTGAATATACTACCAGAAATCCATGCCATGGCCGCACGAGGCGAGGAGCATCTCTACTCGAAGCATTGTGCGGGTAGTGCACCCACACAGACGCTGCTTATGGAGATGTTGCATGCCAAGCGCAAGGTGTAA
Protein Sequence: MDQQQATVQFISSLNMSPFSMQLEQQQQQPSSPALATNQQQQQNSNNNNNNNNNNNDNDGLNSDNDYSAYTLQLTGGAGGGGSTHHTHHQQQQQQQQHYQQQQQQQQQQQNIANNANQFNSSSYSYIYNFDSQYIFPTGYQDTTSSHSQQSGGGGGGGGGGGSGGAGNLLNGSSGGSSTGGYMLLPPATNSSGQNNNSGHMSSGGGPQNSGPGGGNGGNNNSGHPHGGTSATSGHSSGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSMGTDIKPTPLSPGYQQAYPNMNIKQEIQIPQVRKTFQQPVCIPGKYVYIYADTNLDTEIQIQVSSLTQSPDSSPSPIAIALGQVNVSTGGVITTPMNAGNVGGITGGNSAGNGGSNNQNSSSTGSGTGAGGGGGNNAGGGGGGGGNNSGDGLQRSGAGGGGGGGGNGSNCHEPGIGSLQNTAESKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPNVRGIVNKKTVSEGHDNVQAALLDYTLTCYPSVNDKFSRLVNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00914564; iTF_00918171; iTF_00918200; iTF_00917247; iTF_00917271;
90% Identity: iTF_00914564; iTF_00918171; iTF_00918200; iTF_00917247; iTF_00917271;
80% Identity: iTF_00914564;