Lsem004849.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lithophane semibrunnea
Gene Symbol
-
Assembly
GCA_947363905.1
Location
OX376214.1:6670511-6677050[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.044 3.3 8.8 2.9 3 23 248 269 235 269 0.92
2 10 0.044 3.3 8.8 0.1 3 23 292 313 290 313 0.94
3 10 0.002 0.15 13.0 0.4 2 23 336 357 335 357 0.96
4 10 0.0003 0.022 15.6 0.3 1 23 361 383 361 383 0.98
5 10 0.00011 0.0083 17.0 0.1 1 23 388 411 388 411 0.94
6 10 8.2 6.1e+02 1.7 0.1 2 20 418 436 417 440 0.74
7 10 5.2e-05 0.0039 18.0 1.1 1 23 447 470 447 470 0.97
8 10 0.031 2.3 9.3 3.1 1 23 476 498 476 498 0.93
9 10 4.5e-06 0.00033 21.4 3.6 1 23 504 526 504 526 0.99
10 10 2e-05 0.0015 19.4 3.6 1 23 532 555 532 555 0.98

Sequence Information

Coding Sequence
ATGGCTACGAAAAAGGGTAAAGGTCCAGTATTCGATTCGGGATTGTGTCGATGTTGTGGTAATATGAAAAAGTGTCGTGTTTTGAACATTGAATACGAGAGTTTGGGACAAAAAGAAGTTTATTCGGATATGATAATGGATTGCTTCAGTTTACTGCTATCTCACCTAGATGGCGTACCATCAGAGCGGTTGATTTGTGCAACTTGTGTCACTCGGATACGTGATGCACTGAGCTTCAGGAGGCAAGTGCTACGGTGTGAGGAGGCGTTCTTACAAATGAAGATCTATGACGCTAGGAGCGACGACCCAAAAATGGAAAGCCAGTGGCATTCCAAGGTTAATGTTGACATCATTGTGAAGGACGAACCAGGAACACTACAACCGGAGAGTGACGATGAACATTGCACAGACGCATTGGCTGATGCACCAGATGACGACCTAAAACCTGACAAAATGGAAGAAGATCCTGACGACTTACCTCTGAAGCACCACGTCACACAAAGGAAGATTGAAACTAGAAGATTAATAGAATCAGCAGAGAGAGAGCTGGTCAAACAGGAACAGAAAATACCTAAACCGAAGGTGGCGCCCCCACCAATGCCTAAACCAAAACTCCCAATGTCAAAAGTCCAGCAACTGATGCGAGAAAGAGATTCAACATACATGACTGAGACAAACATACTAACTATAGTTGAATACTCCTTCGTTTGCCCTTTTAAGTGCAGACACAACCACCTCCTATGCTACTACTGCGGCGAACTGTACTCTGACCCCGCGTTACTGAGACACCACACGACAGAGATGCATCACCCGAAGAAGTTCAAAGTAACGGAGCACAAAAAAATGGTCAAAATCGATTTAACAAGAATCGATTGTCGATTGTGTGGCGTGAAAATCAATGATTTGGACGAGTTTAAAAGACATATAACTAGTGAACATAAGAAGAAATATTATTTTAATTATAAAGATTCAGTATTGCCGTTCCGGTTAACGAGGGATGAGCTGAAGTGTGCTATTTGTGATGTGCTGTTCCCTTATTTCCATGCTCTGAATAAGCATATGAATGAGCATTTCAGTAATTATGTTTGTGAGACTTGTGGATTGGGTTTCGTCGACAAAGGCCGCTTCATGATGCATCAACAACGCCATGAGGAAGGGGACTTCCCGTGTCCGGACTGCGGGAAAGTGTTCAAGGCGCAGTACAACCGGGACCTGCACATAGACCGCGTACATCGGAAGAAGGGGCGTGTGTACTGCCCCAAGTGTGACGTCAAACTGATGTCCTACCCGCAGAAGTTGAAGCATTTGGTTGAGGTGCATGGTGAAGAGCCTCTAAGTTTCCCCTGTACGATGTGCGAGCGAATATTTGACACAAGAAGAACGCTCACCATTCATAGGCGGAAAGACCATCTGAAAGACTTCAGGTACGAATGCCAGTGCtgcggccaaaagttcttcactcgtttcgccctaaacaaccacatgcctactcacaccggcgaacgtaactttaaatgtaaagtttgtgagaaatgctatcccagattaaaaactttgaaagaccacatgagaatacatacgaatgatcggagataccggtgtcatgtgtgtggacaggcctttatacagaactgtagtctgaaagggcatatgaagagccagcatcctgagtatgAGATGAGGATGTAG
Protein Sequence
MATKKGKGPVFDSGLCRCCGNMKKCRVLNIEYESLGQKEVYSDMIMDCFSLLLSHLDGVPSERLICATCVTRIRDALSFRRQVLRCEEAFLQMKIYDARSDDPKMESQWHSKVNVDIIVKDEPGTLQPESDDEHCTDALADAPDDDLKPDKMEEDPDDLPLKHHVTQRKIETRRLIESAERELVKQEQKIPKPKVAPPPMPKPKLPMSKVQQLMRERDSTYMTETNILTIVEYSFVCPFKCRHNHLLCYYCGELYSDPALLRHHTTEMHHPKKFKVTEHKKMVKIDLTRIDCRLCGVKINDLDEFKRHITSEHKKKYYFNYKDSVLPFRLTRDELKCAICDVLFPYFHALNKHMNEHFSNYVCETCGLGFVDKGRFMMHQQRHEEGDFPCPDCGKVFKAQYNRDLHIDRVHRKKGRVYCPKCDVKLMSYPQKLKHLVEVHGEEPLSFPCTMCERIFDTRRTLTIHRRKDHLKDFRYECQCCGQKFFTRFALNNHMPTHTGERNFKCKVCEKCYPRLKTLKDHMRIHTNDRRYRCHVCGQAFIQNCSLKGHMKSQHPEYEMRM