Basic Information

Insect: Antitype chi
Gene Symbol: Prdm14
Assembly: GCA_947359405.1
Location: OX375834.1:5553596-5564331[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.041 3.2 8.8 2.9 3 23 248 269 235 269 0.92

2 10 1.6 1.3e+02 3.8 0.1 3 23 292 313 290 313 0.90

3 10 0.0019 0.15 13.0 0.4 2 23 336 357 335 357 0.96

4 10 0.00028 0.022 15.6 0.3 1 23 361 383 361 383 0.98

5 10 0.0001 0.0082 17.0 0.1 1 23 388 411 388 411 0.94

6 10 7.7 6.1e+02 1.7 0.1 2 20 418 436 417 440 0.74

7 10 0.00032 0.026 15.4 1.4 1 23 447 470 447 470 0.97

8 10 0.029 2.3 9.3 3.1 1 23 476 498 476 498 0.93

9 10 4.2e-06 0.00033 21.4 3.6 1 23 504 526 504 526 0.99

10 10 3.2e-05 0.0025 18.6 3.1 1 23 532 555 532 555 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.041	3.2	8.8	2.9	3	23	248	269	235	269	0.92
2	10	1.6	1.3e+02	3.8	0.1	3	23	292	313	290	313	0.90
3	10	0.0019	0.15	13.0	0.4	2	23	336	357	335	357	0.96
4	10	0.00028	0.022	15.6	0.3	1	23	361	383	361	383	0.98
5	10	0.0001	0.0082	17.0	0.1	1	23	388	411	388	411	0.94
6	10	7.7	6.1e+02	1.7	0.1	2	20	418	436	417	440	0.74
7	10	0.00032	0.026	15.4	1.4	1	23	447	470	447	470	0.97
8	10	0.029	2.3	9.3	3.1	1	23	476	498	476	498	0.93
9	10	4.2e-06	0.00033	21.4	3.6	1	23	504	526	504	526	0.99
10	10	3.2e-05	0.0025	18.6	3.1	1	23	532	555	532	555	0.98

Sequence Information

Coding Sequence: ATGGCTACGCTAAAGGGCAAAGGTCCAGTATTCGATTCAGGTCTGTGTCGATGTTGTGGAAATATGAAAAAGTGTCGTGTTTTGAACCTTGAATATGAGAGTTTAGGCCAAAAAGAAGTTTATTCGGATATGATCATGGATTGCTTCAGTTTACTGCTATCACATTTAGATGGCGTACCATCAGAGCGCCTGATTTGTGCGACGTGTGTGACTCGTATACGTGATGCGCTGGGCTTCAGGCGTCAAGTGCTGCGGTGTGAGGAGGCCTTCTTACAGATGAAGATCTATGATGCTAGGAGTGATGACTCAAAAATGGAAAGTCAGTGGAATTCCAAAGTTAATGTTGACATAGTTGTGAAAACCGAATCCGGCACAATGGATACGGAGAGTGAGGATGAGAATTCTGCGGATGCATTGGCTGATGTTCCAGACGACGAGCTCAAACCGGATAAAATGGAAGAAGATCCTGACGATTTACCACTGATGTACCACGGCTCACTAAAGAAGGAACACACTAGCACACGAATAGAGTCAGACGAGATACAGCCGGTCAAACAGGAACAACGAATACCTAAACCGAAGGTGGCGCCCCCACCATTACCTAAACCAAAACTCCCGATGTCAAAAGTCCAACAACTAATGCGAGAAAGAGACTCAACGTACATGACAGAGACAAATATACTAACTATAGTGGAATACTCCTTCGTTTGCCCCTTCAAGTGTCGACACAACCATCTCCTATGTTATTATTGTGGCGAACTATACTCCGACCCCGCTTTACTAAGGCACCACACAACTGAGATGCATCACCCGAAAAAATTCAAAGTGACAGAGCATAAGAAAATGGTGAAAGTAGATCTGACAAGAATCGATTGTCGACTATGTGCTGTAAAAATCAACGATTTGGAAGAATTTAAGAGACATATATCCAGTGTTCATAAAAAGAAGTATTATTTTAATTATAAAGACTTAGTATTGCCGTTCCGGTTGACAAGGGAGGAACTGAAGTGTGCTATTTGTGATGTGCTGTTCCCTTATTTTCATGCCTTGAATAAGCATATGAATGAGCATTTCAGTAATTATGTTTGTGAGACTTGTGGATTAGGTTTCGTGGACAAGGGCCGTTTTATGATGCATCAGCAACGCCATGAAGAAGGGGACTTCCCATGTCCTGACTGCGGCAAAGTGTTCAAGGCGCAGTACAATAGAGACCTCCACATAGACCGCGTGCATCGGAAGAAGGGTCGTGTGTACTGTCCCAAGTGTGACGTCAAACTTATGTCCTACCCGCAGAAGTTGAAGCATTTGGTTGAGGTACACGGTGAAGAGCCTCTAAGTTTCCCCTGTACGATGTGCGAGCGGATATTTGACAAACGAAGAACGCTCACTATTCATAAGCGGAAGGACCATCTGAAAGACTTCAGGTACGAATGCCAGTGCTGCGGACAAAAATTCTTCACGCGTTTCGCCTTAAATAACCACATGCCAACCCACACAGGCGAACGTAACTTTAAATGTAAAGTTTGCGAGAAATGCTATCCCAGACTAAAGACCTTGAAAGATCACATGAGAATACACACGAATGACCGCAGGTACAGATGTCATGTGTGTGGACAGGCTTTTATACAGAACTGTAGTCTGAAAGGGCATATAAAGAGCCAGCATCCCGAGTATGAGATGAGAATGTAG
Protein Sequence: MATLKGKGPVFDSGLCRCCGNMKKCRVLNLEYESLGQKEVYSDMIMDCFSLLLSHLDGVPSERLICATCVTRIRDALGFRRQVLRCEEAFLQMKIYDARSDDSKMESQWNSKVNVDIVVKTESGTMDTESEDENSADALADVPDDELKPDKMEEDPDDLPLMYHGSLKKEHTSTRIESDEIQPVKQEQRIPKPKVAPPPLPKPKLPMSKVQQLMRERDSTYMTETNILTIVEYSFVCPFKCRHNHLLCYYCGELYSDPALLRHHTTEMHHPKKFKVTEHKKMVKVDLTRIDCRLCAVKINDLEEFKRHISSVHKKKYYFNYKDLVLPFRLTREELKCAICDVLFPYFHALNKHMNEHFSNYVCETCGLGFVDKGRFMMHQQRHEEGDFPCPDCGKVFKAQYNRDLHIDRVHRKKGRVYCPKCDVKLMSYPQKLKHLVEVHGEEPLSFPCTMCERIFDKRRTLTIHKRKDHLKDFRYECQCCGQKFFTRFALNNHMPTHTGERNFKCKVCEKCYPRLKTLKDHMRIHTNDRRYRCHVCGQAFIQNCSLKGHIKSQHPEYEMRM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00908236;
90% Identity: iTF_00925140;
80% Identity: -