Basic Information

Insect: Lithophane semibrunnea
Gene Symbol: baz-2
Assembly: GCA_947363905.1
Location: OX376216.1:6219785-6242365[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.2e-12 3.9e-09 36.5 0.0 3 75 551 626 549 628 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.2e-12	3.9e-09	36.5	0.0	3	75	551	626	549	628	0.89

Sequence Information

Coding Sequence: ATGGGTGCAGCCTGGTGGTCGATGGCATCCCACCTAGCGGCTCAAGACTACCTAGCGCGGCTGCAGGCCTCAGGGTTAAATTTCCCACCCCTGGCGGACCCTTACGCCGCCCTGTCGGCTCTCTCCGGTGGTCAGGGGCTGAAGCAGCCACAGAAACCTGGGAAGTTGTCTAGTCGGAATGAGAGGTCTGGCAGAAGCAGTACATCATCCAGCGCGTCCACAAAAGACAAGAGTCCATCAACAAGCAGCGCCAACTCGCAGAACATGAGTGAGTGGGGATCCTCATACGGTCTACCGAAGACTTCTTCTCCGTCCGCGATGCACCACTCTGCGTCTCTGTCGAGCCTGGCTTCCCTCAACAGCCTGGTGTCTGCTCCTCATCAGAGCAAGCCCAGTAGCAAGCCGTCTGCTGCGCCACAGCCGAGCAAAAAGCCGTCATCGTCATCATCGTCGAGCTCCAAAGGCAAGGAGCGCGAGCTGGCGCTGCTGCGCGGCGACCTCATGCTGGCGCAGGCGGCCGCGCACGGCGCCTACCACGCCGCCGTCGCCGCCGCCGCCAAGGGGAAGAACATGTCGCCGCTGTACCCATTCGGCATGCCGGGGTCTGACAAGGATGGGCGGCACGGCGGGATCGACTCCCTCACTGGCTTGCCGCATACCATACTCAGTGATCCGTCATCAGTCCTGGGTGGGGTACGTTTGCCGCCGGATACGGAAATTATCAAGTATACCTCTTCGTTAGCTGGGCCCAAGGCGGGTTCAGGCACAACGACCCGCGGCCGCAAGAAGACAATCTCGTTAGACCCGCCGCACGTCAGTGTGCATCCCGCCGACAGGAACGCGCCCCTGCCCAGCAAACGGCCTAAACTTGACGAGTACGGCAACTCGCGGTCGTCCGTGGAAGTGATCCGGCTGCCCAACAAACCGGACCGGCCCGGACACAACTCCATGTCCGGCACACCCCCACCCAATCTGTCCGATTATGCAGGGATATCTCGAGAACTGCTACAAACGATAGCTAGTCAGAGCGGCGTGAGCCTGGCCGCGTTGGAGCGCCAGCTCGCGGGCTCCACAGGTGACTATTATGCAGGTCTCAACCTAAGCACTAAGATGGGCGAGGACTCGCCGCTAGACCTGGGCGTCAAGTCTTCAGCGATGGAGGACGACGCGCCGCTAAACCTGTCCCTCAAACCTACTCCTGCGAGTTCGCAAGCCTCCGACGCTCTCTCACGACTGACGTCTCTGAGCAGTTCGCTCAACGCGTCCTCAAGCCATGACAGGATATCCCGTCGCAAGCCCGGCGCGAAGCCCCGGCGCGTGGCGCCCGAGATGAACCCCGTGCCCGACGCGCCGCGGCCCAAGTCCAGCGGCAGCGAGGACAGTGAATCAGTAGCGGGGTGGGCAGGGCGCGAGGGTCGGCCACGCAACTTGGGCAGAGGAGTCAGCAAGCCTAAGAAGAATACTGTGGCCTCCTTGCTGGCGCAGAGTAGGGCTTTGGGCCTTAGGCCTGCGCTGGCGCATCAGTTGCTAGCTGAGACTGACCTGGAAAAACTAAAAGCGCTACTAGGCGAGACTGCGAGCACGGACTCGGAGTGTCCGTCGGACAGCTGTCCGTCCGACTCGGACGCGTCCGACACCAGTCGGAGACCCAACGACGCCCAGCTTAGACTCCCTCTAGCGCTAGGTTGGAAACGTGTGACTGTGATCAAGGGACTATCTCGTAACTGCAGCATCAAAGGCGACGTGACGTATTCGCCGCCCGACCCGCATGCGGGCATCACCATGCGGTCATTACATGAAATACAGAACTTCCTAGACACGAACCCATGTCCACCACTATCGACGGACAACTTCAGCTTCTCTGCGCGCACCGTGCTCGGAGAGTACATCCAGCCGGCCAGCGACGTGGGCGAGCCGCTTGTGTACAACGAGAACGAGATTAATAAGAGATTGGAAGAAGCCCGTATCCTAGCTGGCGCGGGCGGGCGGCCCACGCCGCCGCCGCTGGACCGGCGCATGGAGCTGGCGCGCCTGCAGCAGGCCGCGCGCGACGCACGGCGCGACGCGTCGCACCGCTCGCGGGACCAGGCCCGTCTCGAAAGATCAGAGAAAGCGGAACTAGCGAAACGCGAAAAGGAAGCGAGAAGTCAACAGCTTTTAGAGCATATCAACAAGAATAGAACGCAGTTGACGATCGAGCCCCTCCCTACTGTCCCGAAGACCGGTATCGACGAATGGAAAACACCCGAGATAGTGATGGGACCTGCCACTAAGACGAATAAGGAACGCATTATGCCTCCGATCAGTCTCTCCCTAATACCGGTTAGCGGCCCCAAAGACTCCCAGAACTCCCCAATAAAAACTATAAAATTCGACCAATCAGGATGGAAAGAAGAAATAGAAGAATATAACGCTTTAGACAAAATGAAAGACTTCGCTGAAAAAGCGGCTTTCGATCTACCAAAACGTAAAGACAATAAACAATACGATTTCACGTTAATAAAATCAGCAGAAAAGCGCTTGAAAGCGCCCGAAAAAGAGAACAATCTAGAAAAACTTATAGAATCTTATTCAAGAATAACGGAATTTATAAACGGCTGTGATTGGTCGAAATTACAAGGGGATAAGAGAACTGAAGACCCGAAGTCTATAGAACAGAAATATTTAGATGCGAAAAATGAGTTCATGTCTCAGAATCTGATGTTAATGCCTAAAGACAGTCCGAAATCTGTTCTAAAAGAAGTTATAGATATAAGCGAAGATGACGATATTTTGACAAATATAATGTCAAAGAAAATCAGTAAAGGGACTTTTAGTGTGGGCAAAGATGGTGCCTTATCGATATCAGTGCATCCCCTAGGCAAGGATACGTCATCGGTACGTGAAAAATAA
Protein Sequence: MGAAWWSMASHLAAQDYLARLQASGLNFPPLADPYAALSALSGGQGLKQPQKPGKLSSRNERSGRSSTSSSASTKDKSPSTSSANSQNMSEWGSSYGLPKTSSPSAMHHSASLSSLASLNSLVSAPHQSKPSSKPSAAPQPSKKPSSSSSSSSKGKERELALLRGDLMLAQAAAHGAYHAAVAAAAKGKNMSPLYPFGMPGSDKDGRHGGIDSLTGLPHTILSDPSSVLGGVRLPPDTEIIKYTSSLAGPKAGSGTTTRGRKKTISLDPPHVSVHPADRNAPLPSKRPKLDEYGNSRSSVEVIRLPNKPDRPGHNSMSGTPPPNLSDYAGISRELLQTIASQSGVSLAALERQLAGSTGDYYAGLNLSTKMGEDSPLDLGVKSSAMEDDAPLNLSLKPTPASSQASDALSRLTSLSSSLNASSSHDRISRRKPGAKPRRVAPEMNPVPDAPRPKSSGSEDSESVAGWAGREGRPRNLGRGVSKPKKNTVASLLAQSRALGLRPALAHQLLAETDLEKLKALLGETASTDSECPSDSCPSDSDASDTSRRPNDAQLRLPLALGWKRVTVIKGLSRNCSIKGDVTYSPPDPHAGITMRSLHEIQNFLDTNPCPPLSTDNFSFSARTVLGEYIQPASDVGEPLVYNENEINKRLEEARILAGAGGRPTPPPLDRRMELARLQQAARDARRDASHRSRDQARLERSEKAELAKREKEARSQQLLEHINKNRTQLTIEPLPTVPKTGIDEWKTPEIVMGPATKTNKERIMPPISLSLIPVSGPKDSQNSPIKTIKFDQSGWKEEIEEYNALDKMKDFAEKAAFDLPKRKDNKQYDFTLIKSAEKRLKAPEKENNLEKLIESYSRITEFINGCDWSKLQGDKRTEDPKSIEQKYLDAKNEFMSQNLMLMPKDSPKSVLKEVIDISEDDDILTNIMSKKISKGTFSVGKDGALSISVHPLGKDTSSVREK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00042661; iTF_00111692;
90% Identity: iTF_00809166;
80% Identity: -