Basic Information

Insect: Lithophane leautieri
Gene Symbol: IKZF1
Assembly: GCA_949152455.1
Location: OX424462.1:6927282-6932031[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.19 15 7.0 3.4 2 22 182 202 181 202 0.95

2 15 0.078 6.1 8.2 2.6 1 23 299 321 299 321 0.95

3 15 2.8 2.2e+02 3.3 0.3 2 23 458 479 457 479 0.95

4 15 0.001 0.08 14.1 0.5 2 23 559 580 558 580 0.96

5 15 0.083 6.5 8.1 0.6 1 23 588 610 588 610 0.97

6 15 4.5 3.5e+02 2.7 2.6 1 23 646 668 646 668 0.93

7 15 0.00022 0.017 16.2 4.0 1 23 676 698 676 698 0.99

8 15 0.095 7.4 7.9 1.9 1 23 777 799 777 799 0.99

9 15 4.6 3.6e+02 2.6 0.3 1 23 855 877 855 877 0.91

10 15 0.0071 0.55 11.5 1.0 1 23 970 992 970 992 0.95

11 15 0.0084 0.66 11.2 0.5 1 23 998 1020 998 1020 0.96

12 15 0.0061 0.47 11.7 2.6 1 23 1110 1132 1110 1132 0.97

13 15 0.00015 0.012 16.7 1.4 1 23 1138 1160 1138 1160 0.99

14 15 0.76 59 5.1 2.7 1 23 1252 1274 1252 1274 0.96

15 15 0.0089 0.69 11.2 5.6 1 23 1285 1307 1285 1307 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.19	15	7.0	3.4	2	22	182	202	181	202	0.95
2	15	0.078	6.1	8.2	2.6	1	23	299	321	299	321	0.95
3	15	2.8	2.2e+02	3.3	0.3	2	23	458	479	457	479	0.95
4	15	0.001	0.08	14.1	0.5	2	23	559	580	558	580	0.96
5	15	0.083	6.5	8.1	0.6	1	23	588	610	588	610	0.97
6	15	4.5	3.5e+02	2.7	2.6	1	23	646	668	646	668	0.93
7	15	0.00022	0.017	16.2	4.0	1	23	676	698	676	698	0.99
8	15	0.095	7.4	7.9	1.9	1	23	777	799	777	799	0.99
9	15	4.6	3.6e+02	2.6	0.3	1	23	855	877	855	877	0.91
10	15	0.0071	0.55	11.5	1.0	1	23	970	992	970	992	0.95
11	15	0.0084	0.66	11.2	0.5	1	23	998	1020	998	1020	0.96
12	15	0.0061	0.47	11.7	2.6	1	23	1110	1132	1110	1132	0.97
13	15	0.00015	0.012	16.7	1.4	1	23	1138	1160	1138	1160	0.99
14	15	0.76	59	5.1	2.7	1	23	1252	1274	1252	1274	0.96
15	15	0.0089	0.69	11.2	5.6	1	23	1285	1307	1285	1307	0.98

Sequence Information

Coding Sequence: ATGGGTCTCCAATACGCAGAGAGAGAACTAGTCAGTTGCAAAAGTGATTCTAATGACGGTACAGCGTCTGACGCAATCACCAGAAAAGAGACTTCGCAAGATGGATACAACCAGCTTTCACCAACCCACAGCGCAGACGAGAagcaacaaaaacaaagcagaAAGATTCCTCGACCAATACCACAACTCATACCGTTAAATTCTTCAACACCCAACCAAAAACAAACCTGCTCTGGGGAACCTCCGCAGAAAAAGTTCAAGGAATCTTTACCCATCGACATTGAAGATGTGTCTGCTGAGAATACTCTTCTACCAGCAAATCCATCAATAAAAGAGACTGCAGGTCGAAAGAAAAATGAATCATTTTTCGACAGATTAAAAGAAAGACTGCTTACAGAAACAGGCGAAGAAGGCTCACTAATATGCAAGATCTGTGGATTTGAAAGTAAATGCTTGTCAGAACATTCTGTCCACGAGAAAAATTGTTCTCCACAAACGAACAGGATCAATGCAAACACGTCGCTTAAAAGTTTAAGTTCCACTCGATGCCAGAATTGCAGACACAGGTGTAAATCTAGCGCTGACTTGTACATCCACATGCAAACATGCGGCAAGAGCGAAAAACTCGATGACGAAAACactatgaaaaatgaaaacagTAGTGATGAAGTCATTCCAATCCATGAAAAAGAGACTGAACCACACCCAATGGAAAACGTCGTATTCGTATGGAACAACATTAATCATGACCCTAACAAGTTTGATATACCTTTAGACATAAACATAAATGATGATTCCACTCTACCAGAAATACACCGAAGTTTTGACGCTGAGATTGTTGATGAAAATGAAAGCATGAATTTGTCGCCCAGTCAAGCTATTGGAAGGAAGGTATTTAAATGTCCACATTGTCCATTTTTCTCCACGACAGCGTCCAGATTTCATGTTCATATCGTGGGCCACTTAAACAAGAAACCATTTGAGTGTTCCCTCTgcaaatataaatctaattggAGATGGGATATAACCAAACACATTAAACTGAAATCTGCGAGGGATCCTGAACATAACGAAGCAAAAGTACTTATGACCGACGAAACAGGTAGAAGAAACTATAGCAAGTACAACAAATTCTTAGCGATGCctgttttaaatgaaaatggtgaaaaTGAGTTTCATTACCTGGATCCTAATACTGCAGTCGACAGCACGATGGAAATGGATGAATCATTTAATGATATATCAGACGTTATGAATGTACAATTTGAAATACAACCGCTTAACTTACAGACTCAACACAGTGAAGATAGTTACAACTATATTGATAACAGAGGTCTCAATGATATGAAGAAACCCAAGAAAACCTTATGGAAATGTAAAAGATGTAATTACAAagATCCCTCAAGAGAAGCTCTTTTAGAGCATGTACGTGAACACTCCAGATCGGATGGCATCCATGACGAACTAAATAAACCGCCTATCAAGAAACCTGAAAATAATACGCCCGACCCAGCAGACCTGGCGTATCGTTGTGGCCACTGTAATCAATTATCTAATTGGAAACATGTCATACAGCGCCATTGCCGATTAAAACACGATGGAGTGATCAAAGTGATAACTACTGTTAAACCAAAACCTGACCCACCAATGAACATCAATGAGATCAACATTGACACTTGCAACAAGTGCCCGTACAGAACGAGTGACAAGAAACTACTCATTGCTCATTTACAACAGCATCAGCCCTCGCCGAACTCTATTTTCAAGTGCTACTTCTGCCCATTCTTCGTAAAGGATGAGCAAGAATTAATCCAACATCTACTCCTGCATGGTATCACTGACCCAGAAGATTACATCGCAAAAGCAATGGGAACTAAATCTCCAGGACCAGAACCGCAAGCACCTGTTACTACGACATTAAACTCCACCAAGCGTCACAAATGCATAGAATGTCCATACGAAACAAATAGTAAATCACAATTCATGTACCACGAACAGTTTCATCGACTTCCGGCTGATACACCTTATAAGTGTCCAGAATGCAACTACAGCGTATCTAAGAGACACCTGCTGCATCAGCATCTCCGAGTACACGGAATCAAAAGAATTGAAACTGAAGCCGAATTAGAAGCAGCACAAAACAAGCTAGCTAAAATGGACTTCCATATTAATCTTGATGAAATACCATATGTCTGGGTTTCTGCCAAGAATGAGTTTCATAAAATGTACAAGTGCCGATATTGTTCATACGTTAATGCTGTAAAAAGCAAAATACCAAATCATGAAAAAATTCATTGCATCGTATTCGAAAACAATGATACAACTATCTACAAGTGTTTGGAATGCAAATTCACATGTGATAACGCCGGCAGGCTAGCAGAGCATTCCAAAACTCACGGGGAAATATATGGTCGCATTTATTGTCCCGTTGAATATGATGTACCTGATGATGATCAAATCACTAAATTAAGAAAGGTTATAGAAATTGAAAAGTCAGCAAATCCAGAAAGTTTCTCTAGAGATGAAGGCACTACGCATGAATtaagagaaataaaattattatatttttgtcaaaAGTGCCCAGCAAGATTTCTTGAAGACCGTGAACTAGAAGCTCATGAAAAATATCATGATGTAACATTGCccaataaatgtaaaagttgtGACTTTTCAGTCACCGAAGAAAATGAATTAGGGGCACATGATACCGTGCACACAGATGAATATCACACAAAAACGAAGATGCTTAAATTTGTTCACCACTCGCATCCTTTGCACAAACAACCAGTGCTAGAGTTTTTACTCTGTTCAAATACTTCAGAGATTACGTGGAGAGCCACTGGACCAAGTAAACCTGAACATATCGAAAGTCCTATGAAAAAAGATACAAAACACGTgccaaaacaatattattgcaaaCAATGTCCAGCAAAGTTCTTCAAAAGTTCCGCGCTTACCTATCACTTGGGACTACATGGAGGTGAGGGCGAATTTAAATGCAAGAAGTGTAATTACGCTGTGAAGAACGTTGGTAATCTAGGCAAACATGAATTACTTCACGAAAATGAGAACAAGACTACAACTTGTGATTATGAATCTGGTGAAGATAtggattataaaaatattcctttGTCGGGCACAGATTTGTTCCAGAGAAAGACTGAGGCTCAAAAAAGAGTATTAACTGATAAAGATAAGTTAGTTAAGCCGAACGACCATTTTCCGCCTGTCTTACAAGCCGATCCTCAATTCGGTTATTTAATGCATGGTAATCCTGAATTTATATATCCCACCTACCTGAAAAATGGACGTCAAAAAGAAAAGCGATACAAATGCCACAAGTGCCCCTCAGCTTTTGAGAAAAGAGAACAATATAAAATTCATTTGTCATTGCACGGCTCCAAGCAAAGATATAAATGTGAGTTATGTGATTATTCAGTGAAATATTACGCTAATTACGTTCAACATATGCGAAAACATCAAATGAACGATGAAGCTCAagctgaaagaaagaaagacaataATGATTTTACAGAATCTGAACATCAAGAAGACGTTAAACAAGACGATAGCAGTGATAACATTAAACTTGCAATAAAAACTATGCCAAAAGGAGCTGCTAAGAGCGACTTTCAACAGTTCTCAATTAGCGACCAGCAAACACTCAGACTGCTGCAGAGGAGACGGTCAATGAATAATTCTGGAAAGGACCACAGCACTACTGAAATTTCGCCGATTAAAGAGCGCAAAATGCACATGTGCCTGTTATGTCCCTACACTAACCAACGTCAAGACTCTTTAAGCAATCATTACAGAAGGCATGGTGACACCGACGTTCTGAACGGAGGAAGTCATAAATGTTCCCATTGCGACCTAGTGGTTGTTCAGTCGCATTTCCTTCGGGAACATCTGAAGACACACTTCAACTACCACAAAACTCTTATTCCCGAATGTTTTGTGGCTAACGAAGCTGTTAGTTTTACCATAACGAAATTGGATGAAGATAGTGAATCAGTTGATCTCAAATTAGACATGCAGAACAAGAGTTTTGCATGTAATGACGAAAAGATATTTGTGAAAATTAAAACTGGAGAGTTATTGGTGGAATAA
Protein Sequence: MGLQYAERELVSCKSDSNDGTASDAITRKETSQDGYNQLSPTHSADEKQQKQSRKIPRPIPQLIPLNSSTPNQKQTCSGEPPQKKFKESLPIDIEDVSAENTLLPANPSIKETAGRKKNESFFDRLKERLLTETGEEGSLICKICGFESKCLSEHSVHEKNCSPQTNRINANTSLKSLSSTRCQNCRHRCKSSADLYIHMQTCGKSEKLDDENTMKNENSSDEVIPIHEKETEPHPMENVVFVWNNINHDPNKFDIPLDININDDSTLPEIHRSFDAEIVDENESMNLSPSQAIGRKVFKCPHCPFFSTTASRFHVHIVGHLNKKPFECSLCKYKSNWRWDITKHIKLKSARDPEHNEAKVLMTDETGRRNYSKYNKFLAMPVLNENGENEFHYLDPNTAVDSTMEMDESFNDISDVMNVQFEIQPLNLQTQHSEDSYNYIDNRGLNDMKKPKKTLWKCKRCNYKDPSREALLEHVREHSRSDGIHDELNKPPIKKPENNTPDPADLAYRCGHCNQLSNWKHVIQRHCRLKHDGVIKVITTVKPKPDPPMNINEINIDTCNKCPYRTSDKKLLIAHLQQHQPSPNSIFKCYFCPFFVKDEQELIQHLLLHGITDPEDYIAKAMGTKSPGPEPQAPVTTTLNSTKRHKCIECPYETNSKSQFMYHEQFHRLPADTPYKCPECNYSVSKRHLLHQHLRVHGIKRIETEAELEAAQNKLAKMDFHINLDEIPYVWVSAKNEFHKMYKCRYCSYVNAVKSKIPNHEKIHCIVFENNDTTIYKCLECKFTCDNAGRLAEHSKTHGEIYGRIYCPVEYDVPDDDQITKLRKVIEIEKSANPESFSRDEGTTHELREIKLLYFCQKCPARFLEDRELEAHEKYHDVTLPNKCKSCDFSVTEENELGAHDTVHTDEYHTKTKMLKFVHHSHPLHKQPVLEFLLCSNTSEITWRATGPSKPEHIESPMKKDTKHVPKQYYCKQCPAKFFKSSALTYHLGLHGGEGEFKCKKCNYAVKNVGNLGKHELLHENENKTTTCDYESGEDMDYKNIPLSGTDLFQRKTEAQKRVLTDKDKLVKPNDHFPPVLQADPQFGYLMHGNPEFIYPTYLKNGRQKEKRYKCHKCPSAFEKREQYKIHLSLHGSKQRYKCELCDYSVKYYANYVQHMRKHQMNDEAQAERKKDNNDFTESEHQEDVKQDDSSDNIKLAIKTMPKGAAKSDFQQFSISDQQTLRLLQRRRSMNNSGKDHSTTEISPIKERKMHMCLLCPYTNQRQDSLSNHYRRHGDTDVLNGGSHKCSHCDLVVVQSHFLREHLKTHFNYHKTLIPECFVANEAVSFTITKLDEDSESVDLKLDMQNKSFACNDEKIFVKIKTGELLVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01231174;
90% Identity: iTF_00726922;
80% Identity: -