Lhum003380.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Linepithema humile
Gene Symbol
PBRM1
Assembly
GCA_000217595.1
Location
NW:740517-752209[+]

Transcription Factor Domain

TF Family
HMG
Domain
HMG_box domain
PFAM
PF00505
TF Group
Other Alpha-Helix Group
Description
High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 8.7e-14 4.3e-11 42.4 0.1 5 56 1353 1404 1350 1408 0.93

Sequence Information

Coding Sequence
ATGAACAAGCGTCGTAGAACGTCGTCAGTGGCGAGTCGCGGCACCGaggacgacggcgacgataTTCCACCTGAACCGAcgaaaaggaggaaaaaattAGATCCTAGTGACTTGTGCCAACAATTGTATGATGTACTTCGTAATCAGAAGAAGGAAGATGGATCGTTGCTGTGTGATGCTTTCATCCGTGTGCCTAAGCGGAGGCAAGAACCAGGATATTACGAAGTCGTTTCTAATCCTATCGATCTTCTGAAAGTGCAGCAAAAGCTGAAAACTGATGAGTATCGTGATATGGATGATCTTGCTGCTGATATTCAGCTTATGGTGAATAATGCAAAAGCTTTTTATATGCGCACGTCTCCTGAATATAAAGATGCAACTGAGTTGTGGGAGTTGtgtataaatactaaaaatcgTATCATGGAAGATTACGAAGATCCAGAACCCAAGGGAAAGCTTATTCTAAAAGTTGGAAGATtggCGCGCAAAGCGACGAGACAAGATGATGCAGAAGATACTTCTGAGAGTTCTACAAATCTTGATGAAGAAACTATGCAGCTATTTGAAGATTTGTTTGCAGCAGTTATGACAGCAACTGATCCTACTGACAATAACAGACCCCTTCATATCATGTTTCAACTTAAACCATCCAAAAAGcTCTACCCTGAGTATTACGATGTTATTGAGACGCCAATCGATTTAAAAACTATCGCAAGAAAGATTCAGGAGGGTGCATATAGTTCAATCGGTGATATGGAAAAAGATTTGATGCTCATGTGTCGCAACGCTTGTCAGTTTAACGAGCCTGGTTCCCAAATCTACAAAGATGCCAAACTCCTGAAGAAGATAATTACCGCGGCCGCGAAGAGACAAGACAGTGGATTTGGCTGTAACACCCCTAAGATCGCCACGACCGCGCCATCGACGAGAAGCAAAAGAGGTAGTCGCACTATGGCGCAATCGTTGATCGCGCAAACTGCGGCATTACTTGACGAAGATGAGGAGAGTGACGATGAGGAGGAAGAACCCGCTGAGACTGAAGAAGCTGATAATCCACAGTGGCAACTATTTCAAACCATCCGGACAGCTCCTAATAATCAAGGTGTGCGGATGAGCGCAGATTTTTGGAAGCTTCCATCAAAGAGATTTTATCCTGATTACTATAAGATGATTAAGAATCctatatctttattacaaatacGTACAAAAATTAAGAGAGGCGAATATGGTACTGTTAGTGAAGTAGCTGGAGATATGAATATCATGTTTGAAAATGCTAAGAAATATAACGTACATACTTCTCGACTGTACAAGTGTGCagttaaattacaaaaaataatgcaagagAAAGTACAAGAACTTCTAGAGTTTGACCAGGATTCCGATTCGGATAGCGAATCTGAAAATAGCTCGCAACAGcctaaattaattaagcgtGCTTCGAATCTACTGACACGAGGGAAATACAAAGACAATATACCGCTGAAGAAGAGACTGTACGCGTTAGTCAAGTGTGTCATAGAATATGTTTGTGAGGACGGTCGGCAGCCTATGTTGATGTTTATGGAGAAGCCTTCCAAGAAACTGTATCCTGATTATTACCAAGTGATAGCGGAGCCCATAGACATGCTGGCGATCGAAGCCAATATTAAAGCAGAGAAGTATCAAAATGAGAACGAATTGATACAAGATTTTAAGttGATGTTCAATAATTGTCGCCAATATAATGAGGAAGGTTCATTGATTTATGAGGATGCTAATACATTAGAGAGAGTTTTGATGGATAAGGTGAAAGAATTGGGACCCTTGCCGGATAATCCCAAGTCGAAATCCACCGCGTCAACGCCAACTAGAAACGTTGGGAGACCGAAAAAAGTAGTACCCCTTCACGTGCAAAAATTGCGAACTTTATACGACACAATTAAAGACTACCATGACGCAAAAGGGAGACAATTGTCTctgattttcatgaaattgcCGAATAAAAATGAGTATCCAGATTATTATGAAGTGATAAAGCAGCCTATACACATGGAAAAGATCGCGTCCACTTTAAAGAATAACGGATACGAGAATCTGGACGAGCTGGTAtccgattttatattaatgttcgACAACGCTTGCAAGTATAATGAACCGGACTCACAAATATACAAGgaCGCCTTGATACTACAAAGATTAGTGTTGCAAAGTAAGCTGCAGCTGAGTGAGGATGAGGAAAGTGTTCCCGACGTTTCAGCTGCTATTCAAGAGTTACTAGCAACAATATTCACAGCGCTTTACAATCACCAGGATGAGGAGGGCAGGTGTTACTCCGATTCTATGGCAGAACTTCCGGAGCATGATATCGTTGATGGCAAAAAggtACGAGGATTGTCATTGGACTTGATTAAAAGAAGATTGGATAGAGGAGTTTATAAAAGGTTAGATCGGTTCCAAGAAGACGTTTTCACCTGCTTGGAGAGAGCGCGAAAGTTATCGCGCACAGATTCACAGCCGTTCGAAGACAGCGTGGAGCTTCAAGCGTTTTTTCTACGTACTCGCGATGAAGCTACTCGCGGAGGGGACTTGCTGCATTCGCCAGCGTTAAATTATACACTCCTGGATTTGTCAACGCAGGTTGCGGAActcaaaagaataaaacaacAGCAGGAATTGAATCTGCCAAATGAAGATGAGAGCTGCGACGGAAATGAGACAAAAGACTCTGAAACAAACACCAATACAGACACGAACAACAGTGACAATGGAGGATCTATGAGTTTCAACCAGGAAGTGTACAGAGCCGGCGACTTTGCGTACATCGAGCCTACTGAAAGGGGCATGGAATATAGTGTGGTTCTCATAGAAAGGCTTTGGACTAACGGAGAGGGCCAACAAATGCTGTACgggaatttattttacagaccGAGCGAAACGTATCACGTGGCGTCGCGGAAGTTCCTGGACAAGGAACTGTTTAAGAGTGACGCCAAGGTGGCGATACCATTTGCCAAAGTAGCAGGCAGATGTTGTGTTCTAAGTGTAAAGGATTATTTTCGAATGCAGCCGGAAGGATTCCTCGAGAAAGATGTTTACGTATGCGAATCGCGTTACTCCACGAAAGCCAGAGCCTTCAAGAAGATCAAAGTTTGGAATTTTGATGCGGATCACTTGAAATTAATCCCGCGAGAGAAGCCGTTGGAACCGAAGCGCGTGATTTCTGTATATAAAGAGCGATTAGAGAAACACAAAGAGGAAATCGCCGAATTGGAGGAAGGAGAGAAACTGCTGGAAAAGGAAAGACCTAATGTGATATTGTATAATCCGGAAGATACGGAAAATACATATTACGAGCAGTACAATACGTGCGTGGGATCGGTGAAAACAGGCGATTTCGTTTATGTAGCGACAGATGGGGGCAGACAGCAAATAGCACAAATCGATGCTATATGGTCGACCAAAGATGGGAAATGTTATTTCAAAGGCCCCTGGTTGCTAATGCCTACAGAAGTGCCACATACacctacaaaattattttataagcaaGAACTGTTTTTATCCACCGTAGATGGTACTCATCCCATTGTAGCTATTGTTGGAAAGTGTGCCGTCCTTGATTACGGAGAATACATATGTAGCAGACCGACGGAAATCCCAGAGGATGACATATACATTTGCGAGTCGCTGTACGATGAAAGTAAGAACTTTATAAAGAAACTCAACCAGGAAGGTTTAAAGAAGTTCAACCATTCGTCGACGGTGACCGAAGACGAGATCTACTTCTTCCGTAGGCCTATCAATCCTGCCAAAGTTTCGAGCGATGTGGCACAGACGCAAAATCAAGTCAAGTCCGTCACGCCCAGCTCGGCTCAATTTGAAATGGAAGCGTCACCATTGTTACCGAAGCTGGAACCCGATGTACTAAGCATGGGGGTAGGATTAGGAGTAGGAGTTGGGGAGGACAGCATGGACGCTAGTGGTCCACCATCCGTGGGATCTACGGAAGCTCAACCGGTGCTCTCCAATACTCAAACACCTGTGTCGACTAAGAAGAAAACGACGGGTAAGAAATTAGTTACGGGCTATATTTTGTATTCGAGTAAAATGCGAACGCAGATTACACAAAACAATCCTGAATCGTCCTTCGGAGAGATTAGCAGAATTGTTGGCAACGagTGGCGAAAACTGCCGGCAGGGGAGAAGCAAGCCTGGGAAGAGCGGGCGATCAAGATGAACGAGGACGGCGGCCAGCTGAAAGGGACCACTACGGTGGGCACAAACGCCATACAGGATGTAGTGTACGAGTGCTGTTGGGATAACTGCGACTGGCAGTTCGAGGACATGACCGACTGCATCGATCATTGCATCGCGGAGCAAAACGGTCATGTACAATCGTCATTCGCGAACGCTCCTAGCGATGTGGAATATCAGTGTCAATGGCGTGGCTGCGGTAGAACGAAGAAATCCATTCCGCCGTTCCCAAATGTACAGAGACTCGCGAGACACGTCAAAGAAGTGCACATTCTCAAGTCCCACGGACGTATAATACCTCCTTCCGAAAGAAGCAGaAATTATATGCCTTCAAAGGGACCGACGGTATTGCCACCGATGGAAACAGAAACTTCAGCAGCCGCAACTCAAACGAGCAATTTACCTGCCGCCAAGCAACCAGAGCCAATGTTTGTCGCAGTACCGCCGAGACCGAGCCGCGTATTGCATTCCGATGCCTATTTGAGGTACATCGAAGGATTAAACGTAGAGAATCGTTACATATCAAATTGGGATAAGCAAATGAACGCCAATCCGGATAATACACAAATCCCCGATGTAACAAAGCTGCCCGCCGAGTGGTTGGGCAACGGCGTGGGCAATCACGGGAACGTCGTGAACGCATTATGGACACTCAGAAACATGATGATGCGGGATGTGTTGGCCatcaataaaactttatag
Protein Sequence
MNKRRRTSSVASRGTEDDGDDIPPEPTKRRKKLDPSDLCQQLYDVLRNQKKEDGSLLCDAFIRVPKRRQEPGYYEVVSNPIDLLKVQQKLKTDEYRDMDDLAADIQLMVNNAKAFYMRTSPEYKDATELWELCINTKNRIMEDYEDPEPKGKLILKVGRLARKATRQDDAEDTSESSTNLDEETMQLFEDLFAAVMTATDPTDNNRPLHIMFQLKPSKKLYPEYYDVIETPIDLKTIARKIQEGAYSSIGDMEKDLMLMCRNACQFNEPGSQIYKDAKLLKKIITAAAKRQDSGFGCNTPKIATTAPSTRSKRGSRTMAQSLIAQTAALLDEDEESDDEEEEPAETEEADNPQWQLFQTIRTAPNNQGVRMSADFWKLPSKRFYPDYYKMIKNPISLLQIRTKIKRGEYGTVSEVAGDMNIMFENAKKYNVHTSRLYKCAVKLQKIMQEKVQELLEFDQDSDSDSESENSSQQPKLIKRASNLLTRGKYKDNIPLKKRLYALVKCVIEYVCEDGRQPMLMFMEKPSKKLYPDYYQVIAEPIDMLAIEANIKAEKYQNENELIQDFKLMFNNCRQYNEEGSLIYEDANTLERVLMDKVKELGPLPDNPKSKSTASTPTRNVGRPKKVVPLHVQKLRTLYDTIKDYHDAKGRQLSLIFMKLPNKNEYPDYYEVIKQPIHMEKIASTLKNNGYENLDELVSDFILMFDNACKYNEPDSQIYKDALILQRLVLQSKLQLSEDEESVPDVSAAIQELLATIFTALYNHQDEEGRCYSDSMAELPEHDIVDGKKVRGLSLDLIKRRLDRGVYKRLDRFQEDVFTCLERARKLSRTDSQPFEDSVELQAFFLRTRDEATRGGDLLHSPALNYTLLDLSTQVAELKRIKQQQELNLPNEDESCDGNETKDSETNTNTDTNNSDNGGSMSFNQEVYRAGDFAYIEPTERGMEYSVVLIERLWTNGEGQQMLYGNLFYRPSETYHVASRKFLDKELFKSDAKVAIPFAKVAGRCCVLSVKDYFRMQPEGFLEKDVYVCESRYSTKARAFKKIKVWNFDADHLKLIPREKPLEPKRVISVYKERLEKHKEEIAELEEGEKLLEKERPNVILYNPEDTENTYYEQYNTCVGSVKTGDFVYVATDGGRQQIAQIDAIWSTKDGKCYFKGPWLLMPTEVPHTPTKLFYKQELFLSTVDGTHPIVAIVGKCAVLDYGEYICSRPTEIPEDDIYICESLYDESKNFIKKLNQEGLKKFNHSSTVTEDEIYFFRRPINPAKVSSDVAQTQNQVKSVTPSSAQFEMEASPLLPKLEPDVLSMGVGLGVGVGEDSMDASGPPSVGSTEAQPVLSNTQTPVSTKKKTTGKKLVTGYILYSSKMRTQITQNNPESSFGEISRIVGNEWRKLPAGEKQAWEERAIKMNEDGGQLKGTTTVGTNAIQDVVYECCWDNCDWQFEDMTDCIDHCIAEQNGHVQSSFANAPSDVEYQCQWRGCGRTKKSIPPFPNVQRLARHVKEVHILKSHGRIIPPSERSRNYMPSKGPTVLPPMETETSAAATQTSNLPAAKQPEPMFVAVPPRPSRVLHSDAYLRYIEGLNVENRYISNWDKQMNANPDNTQIPDVTKLPAEWLGNGVGNHGNVVNALWTLRNMMMRDVLAINKTL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00730037; iTF_00769602; iTF_01254774; iTF_00730716; iTF_00729279; iTF_01395105; iTF_01475430; iTF_00253544; iTF_01473162; iTF_01474667; iTF_01130796; iTF_01473901; iTF_00252049; iTF_00255060; iTF_00292250; iTF_00252796; iTF_00254303; iTF_00865985; iTF_00864617; iTF_00860365; iTF_00865294; iTF_00863248; iTF_00866682; iTF_00863931; iTF_00861116; iTF_00861853; iTF_00219778; iTF_01077443; iTF_00293700; iTF_00625476; iTF_00306245; iTF_01228997; iTF_00763206; iTF_00868774; iTF_00391272; iTF_00633610; iTF_01255530; iTF_00109804; iTF_00393580; iTF_01087180; iTF_01245198; iTF_00867375; iTF_00264977; iTF_00298289; iTF_00183923; iTF_00770355; iTF_00343156; iTF_01232980; iTF_01454068; iTF_00296757; iTF_00295225; iTF_00294454; iTF_01497398; iTF_00024599; iTF_01198647; iTF_00397272; iTF_00398062; iTF_00264249; iTF_00295993; iTF_00652697; iTF_00966010; iTF_00291516; iTF_00297532; iTF_01169148; iTF_01199388; iTF_00292925; iTF_01071005; iTF_00905406; iTF_00183264; iTF_00762528; iTF_00773792; iTF_01228352; iTF_01409089; iTF_01422210; iTF_00126691; iTF_00996323; iTF_01492868; iTF_01493568; iTF_00159091; iTF_00181285; iTF_00754630; iTF_01508839; iTF_01055970; iTF_01056796; iTF_00057930; iTF_01103530; iTF_01207339; iTF_00050927; iTF_00059439; iTF_00263444; iTF_01364628; iTF_00721242; iTF_01101306; iTF_00266436; iTF_00829480; iTF_00265673; iTF_00262637; iTF_01100566; iTF_01299158; iTF_00828760; iTF_00439453; iTF_00629083; iTF_01057627; iTF_00841053; iTF_01379197; iTF_00459734; iTF_00058686; iTF_00232585; iTF_00676001; iTF_00217730; iTF_00221891; iTF_00215687; iTF_00227944; iTF_00222506; iTF_00220559; iTF_00219091; iTF_00229331; iTF_00231298; iTF_00963170; iTF_01232386; iTF_01234326; iTF_01235007; iTF_01420258; iTF_01419621; iTF_01420913; iTF_00303011; iTF_00360195; iTF_01123043; iTF_01233635; iTF_00088804; iTF_00087143; iTF_00087979; iTF_00085356; iTF_00084532; iTF_00086260; iTF_00982948; iTF_01269028; iTF_01267542; iTF_01268250; iTF_01512164; iTF_00117989; iTF_00214373; iTF_00231963; iTF_00228645; iTF_00760965; iTF_00225895; iTF_01424359; iTF_01067593; iTF_01066922; iTF_01070346; iTF_01512812; iTF_01513452; iTF_00961805; iTF_00223854; iTF_00223169; iTF_00230670; iTF_00873774; iTF_01418979; iTF_01122414; iTF_01065551; iTF_00226576; iTF_00225217; iTF_01270480; iTF_00733937; iTF_01069649; iTF_00216370; iTF_01417683; iTF_00140564; iTF_00684148; iTF_01514805; iTF_00963830; iTF_00214999; iTF_01068279; iTF_01514135; iTF_00230008; iTF_00233208; iTF_00221242; iTF_01089978; iTF_01498202; iTF_00962491; iTF_00218396; iTF_01068956; iTF_01066237; iTF_00982270; iTF_01539584; iTF_00127434; iTF_00128953; iTF_00129722; iTF_01405674; iTF_00046955; iTF_00047945; iTF_00280587; iTF_00286315; iTF_01036994; iTF_01487018; iTF_01035406; iTF_00287207; iTF_00079912; iTF_01190319; iTF_01274457; iTF_01036186; iTF_00756622; iTF_01488558; iTF_01520206; iTF_00309487; iTF_00714359; iTF_00713642; iTF_01380586; iTF_01381307; iTF_00712832; iTF_00452559; iTF_01392751; iTF_00125904; iTF_00141808; iTF_00175728; iTF_00174159; iTF_00175008; iTF_01411489; iTF_01413159; iTF_00939530; iTF_01414155; iTF_00938671; iTF_01412305; iTF_00060192; iTF_01200133; iTF_01048887; iTF_01048210; iTF_00798556; iTF_01120189; iTF_00719392; iTF_00718544; iTF_00385296; iTF_00451920; iTF_00168401; iTF_00438059; iTF_00438734; iTF_01273077; iTF_01273761; iTF_00350994; iTF_00728637; iTF_01537937; iTF_00938003; iTF_00128180; iTF_00224532; iTF_00738325; iTF_00765558; iTF_00885085; iTF_00969590; iTF_00968802; iTF_01423638; iTF_00360887; iTF_00015352; iTF_00417538; iTF_01476900; iTF_00182597; iTF_00014701; iTF_00016019; iTF_00181943; iTF_01261815; iTF_01476152; iTF_01477545; iTF_01523339; iTF_01015792; iTF_00016662; iTF_01355287; iTF_01354588; iTF_01407256; iTF_01422904; iTF_00227257; iTF_01408185; iTF_00217051; iTF_00707836; iTF_00463971; iTF_00708516; iTF_00845253; iTF_01524007; iTF_00304459; iTF_01216754; iTF_00305624; iTF_00200733; iTF_00983581; iTF_01099165; iTF_00879615; iTF_00881227; iTF_00882943; iTF_00880429; iTF_00460502; iTF_00882006; iTF_00676704; iTF_01560415; iTF_00997014; iTF_01421536;
90% Identity
iTF_00225895;
80% Identity
-