Bpol019943.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus polaris
Gene Symbol
PBRM1
Assembly
GCA_014737335.1
Location
JACXIO010000028.1:136521-146540[+]

Transcription Factor Domain

TF Family
HMG
Domain
HMG_box domain
PFAM
PF00505
TF Group
Other Alpha-Helix Group
Description
High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.1e-13 8.5e-11 42.4 0.1 5 56 1341 1392 1338 1396 0.93

Sequence Information

Coding Sequence
ATGAACAAGCGCCGTAGAACATCTTCAGTTGCAAGTCGAGGCACAGAAGATGATGGTGACGATATACCACCTGAACCGACAAAGAGACGGAAAAAAATAGATCCTAGTGACCTGTGCCAACAGTTATATGATGTTCTACGTAATCAAAAGAAAGAGGATGGAACATTATTGTGTGATGCATTTATACGTGTGCCTAAACGTAGACAAGAACCAGGTTATTATGAAGTTGTAACAAATCCTATAGACCTACTAAAGGTTCAGCAGAAACTAAAAACAGATGAATATAGGGACATGGATGATTTAGCAGCTGATATTCAACTCATGGTTAATAATGCAAAAGCTTTTTATATGCGTACATCTCCTGAATATAAAGATGCCACTGAACTCTGGGAATTATGTATAAATACAAAAAATCGCATTATGGAAGAATATGAAGATCCAGAACCTAAAGGAAAACTTATCTTAAAAGTAGGACGACTGGCTCGGAAAGCTACAACGAAACAAGAAGATGCAGAAGATACGTCTGAAAGTTCTACAAATCCTGATGAAGAGACAATGCAACAGTTTGAAGATTTATTTGCAGCAGTTATGACAGCAACAGATCCAGCTGATAATAACAGACCATTGCATACAATGTTTCAACTAAAGCCATCTAAAAAATTATATCCAGAATATTATGATGTAATTGAAACACCAGTAGATTTAAAAACAGTTGCAAGAAAAATTCAAGAAGGGGCCTATAGTAGCATTACAGACATGGAAAAAGATTTAATGTTAATGTGTCGTAATGCTTGCCAATTTAATGAGCCTGGTTCTCAAATTTACAAAGACGCAAAGCTTTTGAAAAAAATTATTACTGCAGCTGCAAGAAAGCAAGATATTGGCTTAAGCAGTACTGTTCCAAAAATTGCAACAACAGCACCATCAACAAGAAGTAAAAGAGGAAGTCGTACTATGGCACAGTCTTTAATAGCTCAAACTGCAACATTACCAGATGAAGATGAAGAAAGTGATGATGAAGAAGATGAACCTGCAGAAACTGAAGAGGCTGATAATCCACAGTGGCAATTATTTCAAACTATCAGAACAGCACCTAACAATCAAGGAGTTAGAATGAGCGAATATTTTTGGAAACTGCCATCAAAGAGGTTATACGCCGATTATTACAAAATGATTAAAAATCCTATTTCTTTATTGCAAATTCGTACTAAAATAAAGAAAGGTGAATATGGTACTGTGAGTGAAGTAGCTGGTGACATGAATATTATGTTTGAAAATGCAAAAAAATATAATATTCATACGTCTAGATTATATAAGTGTGCTGTAAAACTACAAAAAATTATGCAAGAAAAAGTACATGAACTGTTAGAATTTGATCAGGATTCAGACTCAGATAGTGAATTTGAAAATAGCTCTCATCAACCTAAACTTATTAAACGTGCTTCAAATCTGTTAACACGTGGAAAATATAAAGACAATATACCACTGAAGAAAAGATTGTATGCACTAGTTAAATGTGTTATAGAATACGTTTGCGAAGATGGTCGGCAACCAATGTTAATGTTTATGGAAAAACCCTCTAAAAAATTATATCCAGATTATTATCAAGTGATAGCAGAACCAATTGATATGTTAGCCATTGAAGCTAATATTAAGGCAGAAAAATATCAAAGTGAAAACGAATTAATACAAGATTTTAAGTTAATGTTTAATAATTGTCGCCAATACAATGAAGAAGGTTCTTTAATATATGAAGATGCAAATACCCTTGAGAGAGTTCTAATGGATAAAGTAAAAGAATTAGGTCCTTTGCCGGAGACACCCAAACCTACAAAATCAAGTGCATCTACTCCTACTAGAAATGTTGGGAGACCTAAAAAGGTTGTACCACTACACTTACAAAAATTGAAAACTATGTATGACACTATAAAAGATTATCACGATGCAAAAGGGAGACAGTTATCTTTAATTTTTATGAAATTACCGAATAAAAATGAATACCCTGATTATTATGAAGTTATTAAACAACCAATGAACATGGAAAAAATAGCGTCTGCTCTAAAGAATAATGGATACGAGAATTTGGATGAACTCGTATCAGATTTCATATTAATGTTTGATAATGCTTGCAAGTATAATGAACCTGATTCGCAAATATACAAGGATGCTTTAATTTTACAAAGATTAGTTCTTCAAACAAAATTACAATTAAGTGAAGATGAAGAAAGTGTGCCAGATGTATCAGCTGCAGTTCAAGAAATATTAGCAACAATTTTCACTGCTCTTTATAATCATCAAGATGAAGAAGGAAGGTGTTATTCTGACTCAATGGCAGAACTTCCAGAACACGACATAGTTGATGGGAAAAAGATACGAGGATTATCATTAGATTTGATTAAAAGAAGATTAGATCGTGGAGTATATAAACGATTAGATCGTTTTCAAGAAGATGTATTTACCTGTTTAGAAAGAGCTAGAAGATTATCACGTACAGACTCGCAACCTTTTGAGGATAGTGTAGAACTACAAGCATTTTTTTTACGTACTCGTGATGAAGTAACTCGTGGAGGGGATTTATTACATTCACCAGCACTTAACTATACACTTCTTGATCTTTCTGCACAAGTTGCAGAATTAAAACGTGTTAAGCAACAACAAGAACTGTCATTACCTAATGAGGATGAAAGCTGTGATGGCAATGAGACAAAAGATTCTGAAACAAATACTAATACAGAGGGAAGTAATAGTGATAATGGTGGATCTATGAGTTTTAATCAAGAAGTATATAGAGCTGGGGACTTTGCATATATAGAACCTACAGAACGAGGCATGGAATATAGTGTGGTTCTCATAGAACGTCTATGGACAAATACAGAAGGTCAACAAATGTTATATGGCAATTTATTTTATAGACCAAGTGAAACTTATCATGTGGCATCTAGAAAATTCCTTGACAAGGAGTTATTTAAAAGTGACGCTCATGTAGCTATACCTTTGGCAAAAGTAGCTGGAAGGTGTTGCGTACTAAGTGTTAAGGATTACTTTAGAATGCAACCTGATGGTTTCTTAGAAAAAGATGTTTATGTATGTGAATCGCGATATTCTACAAAAGCAAGAGCTTTTAAAAAAATTAAAGTCTGGAATTTTGATCCAGATCATTTAAAATTAATTCCAAGAGAGAAATCATTAGAACCAAAGCGAGTAATATCAGTATATAAGGAAAGATTAGAGAAACACAAAGAAGAAATTGCTGAGTTAGAGGAAGGAGAAAAATTGACAGAGAAAGAAAGACCTAATGTGATATTATATAATCCAGATGATGCAGAAAATACATATTATGAACAATATAATNACATACAACAAATTGCACAAATTGATGCTATATGGTCGACAAAAGATGGAAAGTGTTATTTTAAAGGCCCATGGTTGTTAATGCCTGCAGAAGTGCCACATGCTCCTACTAAGTTATTTTACAAACAAGAACTATTCCTATCTACAGTTGATGGTACTCACCCTATCGTGGCCATTGTTGGAAAATGTGCCGTCCTTGACTATGGAGAATACATTTGTAGTCGACCGACAGAAATTCCAGAAGATGATGTATATATTTGTGAATCGTTATACGATGAAAGTAAAAACCTCATGAAAAAATTAGGACAAGAAGGTTTAAAAAAATTTAATCATAATTCAGCAGTAACTGAAGATGAAATTTACTTCTTCCGAAGACCTATTAATCCAGCTAAGATTCCGGGCGATGTGGCTCAGACGCAAAATCAAGTCAAGTCTGTTACTCCTAGTTCAGCTCAATTTGAAATGGAAGCATCACCATTGTTACCGAAGCTGGAACCCGATGTACTAGGCATGGGAGTAGGATTAGGAGTGGGAGTAGGAGTAGGAGTTGGGGAGGACAGCATGGATGCTGGTGGTCCACCGTCCGTTGGATCTGCAGAAGCTCAACCGGTGCTCTCCAATACTCAGACACCTGTGTCGACTAAAAAGAAAACGGCGGGTAAGAAATTAGTTACGGGCTATATTTTATATTCGAGTAAAATGCGAACGCAGATTACACAAAACAATCCTGAATCATCCTTTGGGGAGATTAGCAGAATTGTTGGCAACGAGTGGAGGAAATTGCCAGCAGGAGAAAAACAAGCTTGGGAGGAAAGAGCAATTAAAATGAATGAAGATGGTGGGCAACTTAAAGGAAATAATGTTTCAGTAGGCACTAATGCTTTACAAGATGTAGTTTATGAATGTTGCTGGGATAATTGTGATTGGCAATTTGAAGATATGACCGATTGTATCGACCATTGTATTGCGGAACAAAATGGACATGTTCAATCGTCTTTTATTAATGCTGCAAGCGATGTCGAATTTCAATGTCAATGGCGTGGTTGTGGCCGTACGAAAAAATCTGTACCTCCATTTCCAAGTGTACAAAGACTTGCAAGGCACGTTAAGGAAGTACATATCCTTAAGTCGAATGGACGTATAATACCTCCTTCGGAAAGAAGCAAAAACTATATGGCATCAAAAGGTCCAACGATATTGCCACCAATGGAAACAGAAACATCAGCAGCTGCTACACAAACAAGCAACATTTCCGGTGCTAAACAACCAGAACCCATGTTTGTTGCTGTTCCTCCAAGACCAAGTCGCGTATTACATTCAGATGCGTACTTACGATATATTGAAGCACTGAATGTAGAAAATCGGTACATATCAAATTGGGACAAACAAATGAATGCTAATCCTGATAATACACAAATCCCTGATGTAACGAAATTGCCTGCGGAATGGTTAGGCAATGGTGTAGGCAACCATGGAAATGTGGTAAATGCCTTATGGACACTCAGGAACATGATGATGCGAGATGTGTTAGCCATCAATAAAACTTTATAG
Protein Sequence
MNKRRRTSSVASRGTEDDGDDIPPEPTKRRKKIDPSDLCQQLYDVLRNQKKEDGTLLCDAFIRVPKRRQEPGYYEVVTNPIDLLKVQQKLKTDEYRDMDDLAADIQLMVNNAKAFYMRTSPEYKDATELWELCINTKNRIMEEYEDPEPKGKLILKVGRLARKATTKQEDAEDTSESSTNPDEETMQQFEDLFAAVMTATDPADNNRPLHTMFQLKPSKKLYPEYYDVIETPVDLKTVARKIQEGAYSSITDMEKDLMLMCRNACQFNEPGSQIYKDAKLLKKIITAAARKQDIGLSSTVPKIATTAPSTRSKRGSRTMAQSLIAQTATLPDEDEESDDEEDEPAETEEADNPQWQLFQTIRTAPNNQGVRMSEYFWKLPSKRLYADYYKMIKNPISLLQIRTKIKKGEYGTVSEVAGDMNIMFENAKKYNIHTSRLYKCAVKLQKIMQEKVHELLEFDQDSDSDSEFENSSHQPKLIKRASNLLTRGKYKDNIPLKKRLYALVKCVIEYVCEDGRQPMLMFMEKPSKKLYPDYYQVIAEPIDMLAIEANIKAEKYQSENELIQDFKLMFNNCRQYNEEGSLIYEDANTLERVLMDKVKELGPLPETPKPTKSSASTPTRNVGRPKKVVPLHLQKLKTMYDTIKDYHDAKGRQLSLIFMKLPNKNEYPDYYEVIKQPMNMEKIASALKNNGYENLDELVSDFILMFDNACKYNEPDSQIYKDALILQRLVLQTKLQLSEDEESVPDVSAAVQEILATIFTALYNHQDEEGRCYSDSMAELPEHDIVDGKKIRGLSLDLIKRRLDRGVYKRLDRFQEDVFTCLERARRLSRTDSQPFEDSVELQAFFLRTRDEVTRGGDLLHSPALNYTLLDLSAQVAELKRVKQQQELSLPNEDESCDGNETKDSETNTNTEGSNSDNGGSMSFNQEVYRAGDFAYIEPTERGMEYSVVLIERLWTNTEGQQMLYGNLFYRPSETYHVASRKFLDKELFKSDAHVAIPLAKVAGRCCVLSVKDYFRMQPDGFLEKDVYVCESRYSTKARAFKKIKVWNFDPDHLKLIPREKSLEPKRVISVYKERLEKHKEEIAELEEGEKLTEKERPNVILYNPDDAENTYYEQYNXIQQIAQIDAIWSTKDGKCYFKGPWLLMPAEVPHAPTKLFYKQELFLSTVDGTHPIVAIVGKCAVLDYGEYICSRPTEIPEDDVYICESLYDESKNLMKKLGQEGLKKFNHNSAVTEDEIYFFRRPINPAKIPGDVAQTQNQVKSVTPSSAQFEMEASPLLPKLEPDVLGMGVGLGVGVGVGVGEDSMDAGGPPSVGSAEAQPVLSNTQTPVSTKKKTAGKKLVTGYILYSSKMRTQITQNNPESSFGEISRIVGNEWRKLPAGEKQAWEERAIKMNEDGGQLKGNNVSVGTNALQDVVYECCWDNCDWQFEDMTDCIDHCIAEQNGHVQSSFINAASDVEFQCQWRGCGRTKKSVPPFPSVQRLARHVKEVHILKSNGRIIPPSERSKNYMASKGPTILPPMETETSAAATQTSNISGAKQPEPMFVAVPPRPSRVLHSDAYLRYIEALNVENRYISNWDKQMNANPDNTQIPDVTKLPAEWLGNGVGNHGNVVNALWTLRNMMMRDVLAINKTL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00898723;
90% Identity
iTF_01409089; iTF_00219778; iTF_00224532; iTF_00227257; iTF_00217051; iTF_01232386; iTF_01234326; iTF_01235007; iTF_01233635; iTF_01512812; iTF_01232980; iTF_00360195; iTF_00360887; iTF_00625476; iTF_00232585; iTF_00676001; iTF_00217730; iTF_00221891; iTF_00215687; iTF_00227944; iTF_00222506; iTF_00220559; iTF_00219091; iTF_00229331; iTF_00231298; iTF_01418979; iTF_00873774; iTF_00088804; iTF_00085356; iTF_00982948; iTF_01512164; iTF_00117989; iTF_00214373; iTF_00231963; iTF_00228645; iTF_00306245; iTF_00087143; iTF_01424359; iTF_01066922; iTF_01070346; iTF_01255530; iTF_00087979; iTF_00393580; iTF_00223854; iTF_00223169; iTF_00230670; iTF_01065551; iTF_00226576; iTF_00225217; iTF_00733937; iTF_01417683; iTF_00084532; iTF_00086260; iTF_00140564; iTF_00684148; iTF_00214999; iTF_00230008; iTF_00233208; iTF_00221242; iTF_00218396; iTF_01068956; iTF_00982270; iTF_01539584; iTF_01067593; iTF_01405674; iTF_01122414; iTF_00963170; iTF_01420258; iTF_01123043; iTF_01419621; iTF_00961805; iTF_01420913; iTF_00962491; iTF_00865985; iTF_00763206; iTF_00864617; iTF_00860365; iTF_00865294; iTF_00863248; iTF_00183923; iTF_00024599; iTF_00866682; iTF_00966010; iTF_00863931; iTF_00861116; iTF_00861853; iTF_00183264; iTF_00762528; iTF_00391272; iTF_00633610; iTF_00963830; iTF_01520206; iTF_01422210; iTF_01423638; iTF_01422904; iTF_01421536; iTF_00385296; iTF_00264977; iTF_01077443; iTF_00868774; iTF_01523339; iTF_01245198; iTF_00867375; iTF_00730037; iTF_01254774; iTF_01355287; iTF_00264249; iTF_00730716; iTF_01354588; iTF_00729279; iTF_00769602; iTF_00126691; iTF_00303011; iTF_00898723; iTF_01269028; iTF_01270480; iTF_01267542; iTF_01268250; iTF_00127434; iTF_00128953; iTF_00129722; iTF_00109804; iTF_01087180; iTF_01513452; iTF_00125904; iTF_00141808; iTF_00128180; iTF_01514805; iTF_01514135; iTF_01089978; iTF_01099165; iTF_01069649; iTF_01068279; iTF_01066237; iTF_00216370; iTF_01454068; iTF_00765558; iTF_00885085; iTF_00015352; iTF_00417538; iTF_01476900; iTF_00182597; iTF_00014701; iTF_00016019; iTF_00181943; iTF_01476152; iTF_00181285; iTF_01477545; iTF_01015792; iTF_00016662; iTF_01261815; iTF_01407256; iTF_01408185; iTF_01498202; iTF_01169148; iTF_00983581; iTF_01071005; iTF_00773792; iTF_01228352; iTF_01228997;
80% Identity
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