Basic Information

Insect: Leuctra nigra
Gene Symbol: Nr2e1
Assembly: GCA_934046545.1
Location: CAKOHC010002422.1:43327-49951[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 3.3e-06 0.034 14.8 0.0 212 247 282 317 188 320 0.94

2 8 4.6e-06 0.048 14.3 0.1 212 247 331 366 325 368 0.92

3 8 4.6e-06 0.048 14.3 0.1 212 247 380 415 374 417 0.92

4 8 4.6e-06 0.048 14.3 0.1 212 247 429 464 423 466 0.92

5 8 4.6e-06 0.048 14.3 0.1 212 247 478 513 472 515 0.92

6 8 4.6e-06 0.048 14.3 0.1 212 247 527 562 521 564 0.92

7 8 4.2e-11 4.4e-07 30.9 0.1 212 257 576 621 570 627 0.93

8 8 2.4e-19 2.5e-15 58.0 0.0 298 407 648 774 630 776 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	3.3e-06	0.034	14.8	0.0	212	247	282	317	188	320	0.94
2	8	4.6e-06	0.048	14.3	0.1	212	247	331	366	325	368	0.92
3	8	4.6e-06	0.048	14.3	0.1	212	247	380	415	374	417	0.92
4	8	4.6e-06	0.048	14.3	0.1	212	247	429	464	423	466	0.92
5	8	4.6e-06	0.048	14.3	0.1	212	247	478	513	472	515	0.92
6	8	4.6e-06	0.048	14.3	0.1	212	247	527	562	521	564	0.92
7	8	4.2e-11	4.4e-07	30.9	0.1	212	257	576	621	570	627	0.93
8	8	2.4e-19	2.5e-15	58.0	0.0	298	407	648	774	630	776	0.96

Sequence Information

Coding Sequence: ATGAAGCAAGGTCTCCACTTGTTTACATATTATTGCACCTTGTTGCTAGCACTAGACTTAACTCCCCTGCAGAATGAATGCACGTCACCTGTAACTCCTTCCGCTAACAACAATCCCAATCATCCAGAAAAGACGCCGAATTGCTCTGTTGGGGTTCGCAAAACTGATTTCAAAACACCGGAAGTAGGAAGTACCGAGAGGAAACAACAACTCCCTGCGATCCAAGATGGAGCGGCCACTTGCAGCCCATTGAATCTCGCCGCCCTAAGCTGGGGGAGGGCGGGACGCTTAATCACCTACCTGATTTATACGTCGATTAAACTAATCAAGGGCGGCCAAATAACATGTCGAATTCTGTACGACATTCCTTGCAAAGTCTGTCAGGACCACTCTTCAGGGAAACACTACGGGATATTCGCATGTGACGGTTGCGCTGGATTCTTCAAGCGCTCGATCAGAAGGGCGAGACAGTACGTGTGCAAAGCCAAGTCCGAGGGGGGATGCATGGTGGACAAGACTCACAGGAACCAATGTCGCGCCTGCAGGCTCACCAAGTGTGTGCAAGCCGGCATGAACAAGGAAGCCGTGCAGCACGAACGCGGTCCTCGCAACTCGACGCTGCGCCGCCAGATGGCTCTGTACTTCAAGGAGCCGGAGTCGCCGACGTCTAGTGACGTGAtctcgacgtcgcgacgcacGCCGCCGCACCACGTGCTGGACCTGGCGCTGCCCAAGACGCCCCACCGCCCCCCGCCGCCACCGCATCACCTCCTCCAGCAGGCGGCGTACCTGTGTGCCAGAGCGCCGGCGCCAGTGTTCCAGCTGCCACAGCACAGCGCTGACACGGTGTGCGAGAGCGCTGCTCGCCTGCTGTTCATGAACGTGCAGTGGGCAAAGAGTGTTCCCGCCTTCACACAGCTGCACTACCGCGACCAACTGTTGCTGCTACTGTCCATGACACTTATCCAGCTGCCACAGCACAGCGCTGACACGGTGTGCGAGAGCGCTGCTCGCCTGCTGTTCATGAACGTGCAGTGGGCAAAGAGTGTTCCCGCCTTCACACAGCTGCACTACCGCGACCAACTGTTGCTGCTACTGTCCATGACACTTTTCCAGCTGCCACAGCACAGCGCTGACACGGTGTGCGAGAGCGCTGCTCGCCTGCTGTTCATGAACGTGCAGTGGGCAAAGAGTGTTCCCGCCTTCACACAGCTGCACTACCGCGACCAACTGTTGCTGCTACTGTCCATGACACTTTTCCAGCTGCCACAGCACAGCGCTGACACGGTGTGCGAGAGCGCTGCTCGCCTGCTGTTCATGAACGTGCAGTGGGCAAAGAGTGTTCCCGCCTTCACACAGCTGCACTACCGCGACCAACTGTTGCTGCTACTGTCCATGACACTTTTCCAGCTGCCACAGCACAGCGCTGACACGGTGTGCGAGAGCGCTGCTCGCCTGCTGTTCATGAACGTGCAGTGGGCAAAGAGTGTTCCCGCCTTCACACAGCTGCACTACCGCGACCAACTGTTGCTGCTACTGTCCATGACACTTTTCCAGCTGCCACAGCACAGCGCTGACACGGTGTGCGAGAGCGCTGCTCGCCTGCTGTTCATGAACGTGCAGTGGGCAAAGAGTGTTCCCGCCTTCACACAGCTGCACTACCGCGACCAACTGTTGCTGCTACTGTCCATGACACTTTTCCAGCTGCCACAGCACAGCGCTGACACGGTGTGCGAGAGCGCTGCTCGCCTGCTGTTCATGAACGTGCAGTGGGCAAAGAGTGTTCCCGCCTTCACACAGCTGCATTACCGCGACCAACTGTTGCTGCTGGAAGAGAGTTGGCGCGAGCTGTTCGTCTTGGGCGCCGCGCAGTTCCTGCTGCCCCTGGAGGTCGGCGCGCGCAGCCTCGGCCGCCACGACGCCCTCCTGCACGAGctgagagtgttccaggagacgCTGAGCAAGTTCGAGGCGCTCAGCGTCGACCCCCACGAGTACGCTTGTCTCAGAGCCATCGTGCTCTTCAAGACAGCGTTCGAGAACCAGTCGTCCGTGTCCTCTACATCTGGAAGTCCCGCGTGCGACAGCAAGAGCCTGCGCGAACCCAGTGCTGTCGCCGCGTTGCAAGATCACACGCAGCTGACGCTCAGCAAGTACATCAGCACTGCGCACCCCGCGCAGCCGTTCCGCTTCGGCAAGCTGCTGCTCCTGCTGCCCGCCCTGCGCGCCGTCTCCGCAGCGACCATCGAGGAGCTGTTCTTCAGGAGGACAATAGGACTCATTCCCATCGAGAGGATCATATGTGACATGTACAAGGCCACGGACTTGTAA
Protein Sequence: MKQGLHLFTYYCTLLLALDLTPLQNECTSPVTPSANNNPNHPEKTPNCSVGVRKTDFKTPEVGSTERKQQLPAIQDGAATCSPLNLAALSWGRAGRLITYLIYTSIKLIKGGQITCRILYDIPCKVCQDHSSGKHYGIFACDGCAGFFKRSIRRARQYVCKAKSEGGCMVDKTHRNQCRACRLTKCVQAGMNKEAVQHERGPRNSTLRRQMALYFKEPESPTSSDVISTSRRTPPHHVLDLALPKTPHRPPPPPHHLLQQAAYLCARAPAPVFQLPQHSADTVCESAARLLFMNVQWAKSVPAFTQLHYRDQLLLLLSMTLIQLPQHSADTVCESAARLLFMNVQWAKSVPAFTQLHYRDQLLLLLSMTLFQLPQHSADTVCESAARLLFMNVQWAKSVPAFTQLHYRDQLLLLLSMTLFQLPQHSADTVCESAARLLFMNVQWAKSVPAFTQLHYRDQLLLLLSMTLFQLPQHSADTVCESAARLLFMNVQWAKSVPAFTQLHYRDQLLLLLSMTLFQLPQHSADTVCESAARLLFMNVQWAKSVPAFTQLHYRDQLLLLLSMTLFQLPQHSADTVCESAARLLFMNVQWAKSVPAFTQLHYRDQLLLLEESWRELFVLGAAQFLLPLEVGARSLGRHDALLHELRVFQETLSKFEALSVDPHEYACLRAIVLFKTAFENQSSVSSTSGSPACDSKSLREPSAVAALQDHTQLTLSKYISTAHPAQPFRFGKLLLLLPALRAVSAATIEELFFRRTIGLIPIERIICDMYKATDL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00894817;
90% Identity: iTF_00894817;
80% Identity: iTF_00894817;