Lobt018597.1
Basic Information
- Insect
- Leucophora obtusa
- Gene Symbol
- RHOBTB1
- Assembly
- GCA_949987735.1
- Location
- OX465296.1:994648-999556[+]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 3 3.7e-09 2.8e-06 29.2 0.0 3 45 256 300 254 323 0.80 2 3 1.3e-05 0.0098 17.8 0.1 57 102 398 443 388 448 0.89 3 3 4.3e-18 3.2e-15 58.0 0.1 7 103 476 571 471 578 0.91
Sequence Information
- Coding Sequence
- ATGGATAACGAACAACCACACCAGGAACTTGTTAAGTGTGTGCTTGTTGGTGATACAGCCGTAGGCAAGACACGTTTAATATGTGCTCGAGCATGCAACAAACATGTTTCCCTTTCACAGTTGTTGTCCACTCATGTTCCCACTGTTTGGGCTATAGACCAATATCGTATCTATAAAGATGTTCTAGAACGTTCATGGGAGGTGGTTGATGGTGTGAACGTATCCCTGCGCCTTTGGGACACGTTTGGCGATCATGACAAGGATAGACGTTTTGCATATGGACGTTCGGATGTCGTGTTGCTGTGTTTCTCCATTGCCAGTCCGATTTCGTTGCGCAACTGTAAGGCAATGTGGTATCCAGAGATACGTAGATTTTGCCCTGATGTTCCAGTGATACTAGTTGGCTGTAAAAATGATTTGCGTTACATGTATCGCGATGAGACATATCTCTCATACTTTGGTGAGAGAAGTACATTTGTAAGAGCTGCACTTAAGAGTGATCTTGTTATGCCGGATGAGGCACGTGCTGTAGCCCGAGAACTGGGAGTGGCCTATTACGAAACCAGTGTCTTTACTTATTTCGGGGTGAATGAAGTTTTTGAAAATGCAATACGCTCGGCATTAATAGCTCGTCGTCAACAACGTTTCTGGATGACTAACCTTAAGAAGGTTCAGAAGCCTCTGTTACAGGCACCTTTTCGTCCACCCAAACCACCACCACCAGAGGTGACAGTAGTCGTGGGAAACTTTCGTCAGGACATGTACAATATGTTTCTAGCTCAAACATATACAGATCTCATTCTTGTTGTTGGCACAATTAAATTTCCGGTACACAAGTTTATGGTCGCCGCCGCGTCCAATGTATTCAATCGTCTATTGAATACTGATATTACAGACATGGGAGGACGAAGTAGCAGTGAGTCGAGTATGATAAGTTCCACTTTTGGGGAAGCGACAACTGCCGATTTCAATGACGATACAGAGTGCCTGATACGCAATGAATCGCGTGCACAAAGaaTGTGGGAGCAAATCAAGCGAAGATCGAGCTACCAAGCTCTACCTCTTATCGACTCAAAAAAGCCAAATGAGCTCTATAAAGATTTGCACCATCCTGTATTCCTGAATATACGCATAATTAAAGTAGATAATGGTCGAGGCATCATTTTCAATCAAACAATATTATCACTAACTAAGGCCATAACAACACAGGCTTTGCACCAATGCCTCAAGTTCATTTACACTGGCACCGTTGAAAAAGAATTGAACTGCATTCAGGATATCAAACAAGCTGCGGAGCTTTTGGAACTGCCGCAACTGTCACAATTGCTTGCGAAACCACAAAATGTGTTATCCAGCATAAGTGATGATCCAAATTCTCATATATGTCTAAGTATTAAGGAAAATATGGAAAAACATTGCATGGGCGACGGATGCTTTACGGATATAACTTTTGAACTAGACGATGGTCAAATGAAGGCTCATCGTGCCATATTGGTAGCGCGATGCGACGTGATGCGAGCAATGTTGGCCGGAGATTTTCGAGAAGCCCATTCGAGCGTGATTGTTTTTCCTGGCGTCACTATTTATACATTCCACAAATTGCTTTGCTATTTATATACTGATGAAATACCACATATTTCTGCTGTTAAATGTCTTAATCTCTTGGAATTGGCAAATCGTTTATGTCTGCCCCGTTTGTTAAATTTGGTTGAGTGTCGAGTTATCGAAGATTTAACCATGATTTCACAGAGTGAAACCAATGAAACCGTAGATCACTGTTTGAAACTTTTGGAACCAGTAAAGCTTCACAATGCTCATCAGTTAGCCGAATGGTGCATGTCTTATTTGTGCGTCAACTACAACATAATTTGCAAATATTCAATTAAAGGCCTGAGATCTTTGCATCAGGATAATCAAGAGTATTTGCGTGAGCATAGATGGCCGCCAGTGTGGTATTTAAAAGACTACGATTACTATCAACGTTGTATAaatgaaatgaataaagaatTAAAAAACTCCCGTCGAGATTCACGCAGTGACGACGAGGGTTGTCTTTGTTTTACAGGCGTATTTTCTTGGATGTTAGGCAAACCAAAACAACAGCGGATCACGTCTGGAAATGTGAGTGGAGAAAGCACAAACGATAATCAAATTTTCAACACATTGGGGCACCGAAAATCACTGCGTTTTATTGTGATCTTGCCCGTATTGATTTGTTTCATTTGCACTATTTTGAGTATTTTAATACTATTTCAAATCTACACATAA
- Protein Sequence
- MDNEQPHQELVKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVSLRLWDTFGDHDKDRRFAYGRSDVVLLCFSIASPISLRNCKAMWYPEIRRFCPDVPVILVGCKNDLRYMYRDETYLSYFGERSTFVRAALKSDLVMPDEARAVARELGVAYYETSVFTYFGVNEVFENAIRSALIARRQQRFWMTNLKKVQKPLLQAPFRPPKPPPPEVTVVVGNFRQDMYNMFLAQTYTDLILVVGTIKFPVHKFMVAAASNVFNRLLNTDITDMGGRSSSESSMISSTFGEATTADFNDDTECLIRNESRAQRMWEQIKRRSSYQALPLIDSKKPNELYKDLHHPVFLNIRIIKVDNGRGIIFNQTILSLTKAITTQALHQCLKFIYTGTVEKELNCIQDIKQAAELLELPQLSQLLAKPQNVLSSISDDPNSHICLSIKENMEKHCMGDGCFTDITFELDDGQMKAHRAILVARCDVMRAMLAGDFREAHSSVIVFPGVTIYTFHKLLCYLYTDEIPHISAVKCLNLLELANRLCLPRLLNLVECRVIEDLTMISQSETNETVDHCLKLLEPVKLHNAHQLAEWCMSYLCVNYNIICKYSIKGLRSLHQDNQEYLREHRWPPVWYLKDYDYYQRCINEMNKELKNSRRDSRSDDEGCLCFTGVFSWMLGKPKQQRITSGNVSGESTNDNQIFNTLGHRKSLRFIVILPVLICFICTILSILILFQIYT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01300978;
- 90% Identity
- iTF_01165621;
- 80% Identity
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